Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types

EMBO Reports

Volumn 17, Issue 2, 2016, Pages 178-187

  Li, Jin ^a   Klughammer, Johanna ^a   Farlik, Matthias ^a   Penz, Thomas ^a   Spittler, Andreas ^b   Barbieux, Charlotte ^c   Berishvili, Ekaterine ^c   Bock, Christoph ^a,b,d   Kubicek, Stefan ^a  

^a ERICH SCHMID INSTITUTE OF MATERIALS SCIENCE   (Austria)

^b MEDICAL UNIVERSITY OF VIENNA   (Austria)

^c GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^d MAX PLANCK INSTITUTE FOR INFORMATICS   (Germany)

Author keywords

alpha cells; beta cells; diabetes; marker genes; single cell RNA seq

Indexed keywords

BETA ACTIN; CYTOKERATIN 18; CYTOKERATIN 8; GLUCAGON; HEPATOCYTE NUCLEAR FACTOR 1ALPHA; HISTONE DEMETHYLASE; NEUROGENIC DIFFERENTIATION FACTOR; PANCREAS POLYPEPTIDE; PREALBUMIN; SOMATOSTATIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR PAX4; TRANSCRIPTION FACTOR PAX6; TRANSCRIPTOME; GENETIC MARKER;

ACINAR CELL; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL HETEROGENEITY; CELL LEVEL; CELL SELECTION; CELL SPECIFICITY; CONTROLLED STUDY; DIABETES MELLITUS; ENDOCRINE CELL; GENE EXPRESSION; GENETIC ASSOCIATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE; MARKER GENE; MOUSE; MULTIDIMENSIONAL SCALING; NEXT GENERATION SEQUENCING; NONHUMAN; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SEQUENCE; ADULT; CELL CULTURE; CLASSIFICATION; GENE EXPRESSION PROFILING; GENETIC MARKER; MALE; METABOLISM; PROCEDURES; SINGLE CELL ANALYSIS; STANDARDS;

ADULT; CELLS, CULTURED; GENE EXPRESSION PROFILING; GENETIC MARKERS; HUMANS; INSULIN-SECRETING CELLS; MALE; SINGLE-CELL ANALYSIS; TRANSCRIPTOME;

EID: 84957432156     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.15252/embr.201540946     Document Type: Article

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