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Volumn 7, Issue 1, 2017, Pages

Atp6ap2 ablation in adult mice impairs viability through multiple organ deficiencies

Author keywords

[No Author keywords available]

Indexed keywords

ATP6AP2 PROTEIN, MOUSE; CELL SURFACE RECEPTOR; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATASE;

EID: 85028469036     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/s41598-017-08845-7     Document Type: Article
Times cited : (22)

References (57)
  • 1
    • 33750592956 scopus 로고    scopus 로고
    • Prorenin and its ancient receptor
    • Burckle, C. & Bader, M. Prorenin and its ancient receptor. Hypertension 48, 549-551, doi: 10. 1161/01. HYP. 0000241132. 48495. df (2006).
    • (2006) Hypertension , vol.48 , pp. 549-551
    • Burckle, C.1    Bader, M.2
  • 2
    • 84892468787 scopus 로고    scopus 로고
    • Prorenin receptor and V-ATPase: From Drosophila to humans
    • Rousselle, A., Sihn, G., Rotteveel, M. & Bader, M. (Pro)renin receptor and V-ATPase: from Drosophila to humans. Clin Sci (Lond) 126, 529-536, doi: 10. 1042/CS20130307 (2014).
    • (2014) Clin Sci (Lond) , vol.126 , pp. 529-536
    • Rousselle, A.1    Sihn, G.2    Rotteveel, M.3    Bader, M.4
  • 3
    • 33646160993 scopus 로고    scopus 로고
    • Nonproteolytic activation of prorenin contributes to development of cardiac fibrosis in genetic hypertension
    • Ichihara, A. et al. Nonproteolytic activation of prorenin contributes to development of cardiac fibrosis in genetic hypertension. Hypertension 47, 894-900, doi: 10. 1161/01. HYP. 0000215838. 48170. 0b (2006).
    • (2006) Hypertension , vol.47 , pp. 894-900
    • Ichihara, A.1
  • 4
    • 0036266596 scopus 로고    scopus 로고
    • Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin
    • Nguyen, G. et al. Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin. J Clin Invest 109, 1417-1427, doi: 10. 1172/JCI14276 (2002).
    • (2002) J Clin Invest , vol.109 , pp. 1417-1427
    • Nguyen, G.1
  • 5
    • 84884534005 scopus 로고    scopus 로고
    • Prorenin receptor and insulin resistance: Possible roles of angiotensin II-dependent and-independent pathways
    • Rafiq, K., Mori, H., Masaki, T. & Nishiyama, A. (Pro)renin receptor and insulin resistance: possible roles of angiotensin II-dependent and-independent pathways. Mol Cell Endocrinol 378, 41-45, doi: 10. 1016/j. mce. 2012. 05. 016 (2013).
    • (2013) Mol Cell Endocrinol , vol.378 , pp. 41-45
    • Rafiq, K.1    Mori, H.2    Masaki, T.3    Nishiyama, A.4
  • 6
    • 33747060126 scopus 로고    scopus 로고
    • Increased expression of cyclooxygenase-2 in the renal cortex of human prorenin receptor gene-transgenic rats
    • Kaneshiro, Y. et al. Increased expression of cyclooxygenase-2 in the renal cortex of human prorenin receptor gene-transgenic rats. Kidney Int 70, 641-646, doi: 10. 1038/sj. ki. 5001627 (2006).
    • (2006) Kidney Int , vol.70 , pp. 641-646
    • Kaneshiro, Y.1
  • 7
    • 33745824649 scopus 로고    scopus 로고
    • Prorenin receptor blockade inhibits development of glomerulosclerosis in diabetic angiotensin II type 1a receptordeficient mice
    • Ichihara, A. et al. Prorenin receptor blockade inhibits development of glomerulosclerosis in diabetic angiotensin II type 1a receptordeficient mice. J Am Soc Nephrol 17, 1950-1961, doi: 10. 1681/ASN. 2006010029 (2006).
    • (2006) J Am Soc Nephrol , vol.17 , pp. 1950-1961
    • Ichihara, A.1
  • 8
    • 84951309908 scopus 로고    scopus 로고
    • ZT-25, a new vacuolar H-ATPase inhibitor, induces apoptosis and protective autophagy through ROS generation in HepG2 cells
    • Lu, Y. et al. ZT-25, a new vacuolar H-ATPase inhibitor, induces apoptosis and protective autophagy through ROS generation in HepG2 cells. Eur J Pharmacol 771, 130-138, doi: 10. 1016/j. ejphar. 2015. 12. 026 (2015).
    • (2015) Eur J Pharmacol , vol.771 , pp. 130-138
    • Lu, Y.1
  • 9
    • 84885671482 scopus 로고    scopus 로고
    • The R740S mutation in the V-ATPase a3 subunit results in osteoclast apoptosis and defective early-stage autophagy
    • Ochotny, N., Voronov, I., Owen, C., Aubin, J. E. & Manolson, M. F. The R740S mutation in the V-ATPase a3 subunit results in osteoclast apoptosis and defective early-stage autophagy. J Cell Biochem 114, 2823-2833, doi: 10. 1002/jcb. 24630 (2013).
    • (2013) J Cell Biochem , vol.114 , pp. 2823-2833
    • Ochotny, N.1    Voronov, I.2    Owen, C.3    Aubin, J.E.4    Manolson, M.F.5
  • 10
    • 84901003560 scopus 로고    scopus 로고
    • Autophagy and the (Pro)renin Receptor
    • Binger, K. J. & Muller, D. N. Autophagy and the (Pro)renin Receptor. Front Endocrinol (Lausanne) 4, 155, doi: 10. 3389/fendo. 2013. 00155 (2013).
    • (2013) Front Endocrinol (Lausanne) , vol.4 , pp. 155
    • Binger, K.J.1    Muller, D.N.2
  • 11
    • 85013662528 scopus 로고    scopus 로고
    • Renal Atp6ap2/(Pro)renin Receptor is Required for Normal Vacuolar H+-ATPase Function but Not for the Renin-Angiotensin System
    • Trepiccione, F. et al. Renal Atp6ap2/(Pro)renin Receptor Is Required for Normal Vacuolar H+-ATPase Function but Not for the Renin-Angiotensin System. J Am Soc Nephrol 27, 3320-3330, doi: 10. 1681/ASN. 2015080915 (2016).
    • (2016) J Am Soc Nephrol , vol.27 , pp. 3320-3330
    • Trepiccione, F.1
  • 12
    • 84859980878 scopus 로고    scopus 로고
    • Mutations in vacuolar H+-ATPase subunits lead to biliary developmental defects in zebrafish
    • EauClaire, S. F. et al. Mutations in vacuolar H+-ATPase subunits lead to biliary developmental defects in zebrafish. Dev Biol 365, 434-444, doi: 10. 1016/j. ydbio. 2012. 03. 009 (2012).
    • (2012) Dev Biol , vol.365 , pp. 434-444
    • EauClaire, S.F.1
  • 13
    • 77956635784 scopus 로고    scopus 로고
    • Wnt/Frizzled signaling requires dPRR, the Drosophila homolog of the prorenin receptor
    • Buechling, T. et al. Wnt/Frizzled signaling requires dPRR, the Drosophila homolog of the prorenin receptor. Curr Biol 20, 1263-1268, doi: 10. 1016/j. cub. 2010. 05. 028 (2010).
    • (2010) Curr Biol , vol.20 , pp. 1263-1268
    • Buechling, T.1
  • 14
    • 75649120756 scopus 로고    scopus 로고
    • Requirement of prorenin receptor and vacuolar H+-ATPase-mediated acidification for Wnt signaling
    • Cruciat, C. M. et al. Requirement of prorenin receptor and vacuolar H+-ATPase-mediated acidification for Wnt signaling. Science 327, 459-463, doi: 10. 1126/science. 1179802 (2010).
    • (2010) Science , vol.327 , pp. 459-463
    • Cruciat, C.M.1
  • 15
    • 77956644597 scopus 로고    scopus 로고
    • Trafficking, acidification, and growth factor signaling
    • Niehrs, C. & Boutros, M. Trafficking, acidification, and growth factor signaling. Sci Signal 3, pe26, doi: 10. 1126/scisignal. 3134pe26 (2010).
    • (2010) Sci Signal , vol.3 , pp. pe26
    • Niehrs, C.1    Boutros, M.2
  • 16
    • 60649085140 scopus 로고    scopus 로고
    • Association of (pro)renin receptor gene polymorphism with blood pressure in Japanese men: The Ohasama study
    • Hirose, T. et al. Association of (pro)renin receptor gene polymorphism with blood pressure in Japanese men: the Ohasama study. Am J Hypertens 22, 294-299, doi: 10. 1038/ajh. 2008. 357 (2009).
    • (2009) Am J Hypertens , vol.22 , pp. 294-299
    • Hirose, T.1
  • 17
    • 79955886634 scopus 로고    scopus 로고
    • Association of (pro)renin receptor gene polymorphism with blood pressure in Caucasian men
    • Ott, C. et al. Association of (pro)renin receptor gene polymorphism with blood pressure in Caucasian men. Pharmacogenet Genomics 21, 347-349, doi: 10. 1097/FPC. 0b013e328344cdd2 (2011).
    • (2011) Pharmacogenet Genomics , vol.21 , pp. 347-349
    • Ott, C.1
  • 18
    • 84943742313 scopus 로고    scopus 로고
    • A Novel GLP1 receptor interacting protein atp6ap2 regulates insulin secretion in pancreatic beta cells
    • Dai, F. F. et al. A Novel GLP1 Receptor Interacting Protein ATP6ap2 Regulates Insulin Secretion in Pancreatic Beta Cells. J Biol Chem 290, 25045-25061, doi: 10. 1074/jbc. M115. 648592 (2015).
    • (2015) J Biol Chem , vol.290 , pp. 25045-25061
    • Dai, F.F.1
  • 19
    • 84955685325 scopus 로고    scopus 로고
    • A splice site mutation in ATP6AP2 causes X-linked intellectual disability, epilepsy, and parkinsonism
    • Gupta, H. V., Vengoechea, J., Sahaya, K. & Virmani, T. A splice site mutation in ATP6AP2 causes X-linked intellectual disability, epilepsy, and parkinsonism. Parkinsonism & Related Disorders 21, 1473-1475, doi: 10. 1016/j. parkreldis. 2015. 10. 001 (2015).
    • (2015) Parkinsonism & Related Disorders , vol.21 , pp. 1473-1475
    • Gupta, H.V.1    Vengoechea, J.2    Sahaya, K.3    Virmani, T.4
  • 20
    • 84881230554 scopus 로고    scopus 로고
    • Altered splicing of ATP6AP2 causes X-linked parkinsonism with spasticity (XPDS)
    • Korvatska, O. et al. Altered splicing of ATP6AP2 causes X-linked parkinsonism with spasticity (XPDS). Hum Mol Genet 22, 3259-3268, doi: 10. 1093/hmg/ddt180 (2013).
    • (2013) Hum Mol Genet , vol.22 , pp. 3259-3268
    • Korvatska, O.1
  • 21
    • 20244369597 scopus 로고    scopus 로고
    • A unique exonic splice enhancer mutation in a family with X-linked mental retardation and epilepsy points to a novel role of the renin receptor
    • Ramser, J. et al. A unique exonic splice enhancer mutation in a family with X-linked mental retardation and epilepsy points to a novel role of the renin receptor. Hum Mol Genet 14, 1019-1027, doi: 10. 1093/hmg/ddi094 (2005).
    • (2005) Hum Mol Genet , vol.14 , pp. 1019-1027
    • Ramser, J.1
  • 22
    • 84971238702 scopus 로고    scopus 로고
    • ATP6AP1 deficiency causes an immunodeficiency with hepatopathy, cognitive impairment and abnormal protein glycosylation
    • Jansen, E. J. et al. ATP6AP1 deficiency causes an immunodeficiency with hepatopathy, cognitive impairment and abnormal protein glycosylation. Nat Commun 7, 11600, doi: 10. 1038/ncomms11600 (2016).
    • (2016) Nat Commun , vol.7 , pp. 11600
    • Jansen, E.J.1
  • 23
    • 82655181484 scopus 로고    scopus 로고
    • Prorenin receptor is essential for podocyte autophagy and survival
    • Riediger, F. et al. Prorenin receptor is essential for podocyte autophagy and survival. J Am Soc Nephrol 22, 2193-2202, doi: 10. 1681/ASN. 2011020200 (2011).
    • (2011) J Am Soc Nephrol , vol.22 , pp. 2193-2202
    • Riediger, F.1
  • 24
    • 77954762963 scopus 로고    scopus 로고
    • The (pro)renin receptor/ATP6AP2 is essential for vacuolar H+-ATPase assembly in murine cardiomyocytes
    • Kinouchi, K. et al. The (pro)renin receptor/ATP6AP2 is essential for vacuolar H+-ATPase assembly in murine cardiomyocytes. Circ Res 107, 30-34, doi: 10. 1161/CIRCRESAHA. 110. 224667 (2010).
    • (2010) Circ Res , vol.107 , pp. 30-34
    • Kinouchi, K.1
  • 25
    • 84958709411 scopus 로고    scopus 로고
    • Conditional depletion of intellectual disability and Parkinsonism candidate gene ATP6AP2 in fly and mouse induces cognitive impairment and neurodegeneration
    • Dubos, A. et al. Conditional depletion of intellectual disability and Parkinsonism candidate gene ATP6AP2 in fly and mouse induces cognitive impairment and neurodegeneration. Hum Mol Genet, doi: 10. 1093/hmg/ddv380 (2015).
    • (2015) Hum Mol Genet
    • Dubos, A.1
  • 26
    • 84877976034 scopus 로고    scopus 로고
    • Deletion of the prorenin receptor from the ureteric bud causes renal hypodysplasia
    • Song, R., Preston, G., Ichihara, A. & Yosypiv, I. V. Deletion of the prorenin receptor from the ureteric bud causes renal hypodysplasia. PLoS One 8, e63835, doi: 10. 1371/journal. pone. 0063835 (2013).
    • (2013) PLoS One , vol.8 , pp. e63835
    • Song, R.1    Preston, G.2    Ichihara, A.3    Yosypiv, I.V.4
  • 27
    • 84937796668 scopus 로고    scopus 로고
    • New role for the (pro)renin receptor in T-cell development
    • Geisberger, S. et al. New role for the (pro)renin receptor in T-cell development. Blood 126, 504-507, doi: 10. 1182/blood-2015-03-635292 (2015).
    • (2015) Blood , vol.126 , pp. 504-507
    • Geisberger, S.1
  • 28
    • 84889046552 scopus 로고    scopus 로고
    • Atp6ap2/(pro)renin receptor interacts with Par3 as a cell polarity determinant required for laminar formation during retinal development in mice
    • Kanda, A. et al. Atp6ap2/(pro)renin receptor interacts with Par3 as a cell polarity determinant required for laminar formation during retinal development in mice. J Neurosci 33, 19341-19351, doi: 10. 1523/JNEUROSCI. 1362-13. 2013 (2013).
    • (2013) J Neurosci , vol.33 , pp. 19341-19351
    • Kanda, A.1
  • 29
    • 84966784611 scopus 로고    scopus 로고
    • Adipocyte (Pro)Renin-Receptor Deficiency Induces Lipodystrophy, Liver Steatosis and Increases Blood Pressure in Male Mice
    • Wu, C. H. et al. Adipocyte (Pro)Renin-Receptor Deficiency Induces Lipodystrophy, Liver Steatosis and Increases Blood Pressure in Male Mice. Hypertension 68, 213-219, doi: 10. 1161/HYPERTENSIONAHA. 115. 06954 (2016).
    • (2016) Hypertension , vol.68 , pp. 213-219
    • Wu, C.H.1
  • 30
    • 84936080026 scopus 로고    scopus 로고
    • Nephron-specific deletion of the prorenin receptor causes a urine concentration defect
    • Ramkumar, N. et al. Nephron-specific deletion of the prorenin receptor causes a urine concentration defect. Am J Physiol Renal Physiol 309, F48-56, doi: 10. 1152/ajprenal. 00126. 2015 (2015).
    • (2015) Am J Physiol Renal Physiol , vol.309 , pp. F48-56
    • Ramkumar, N.1
  • 31
    • 84984600809 scopus 로고    scopus 로고
    • Renal tubular epithelial cell prorenin receptor regulates blood pressure and sodium transport
    • Ramkumar, N. et al. Renal tubular epithelial cell prorenin receptor regulates blood pressure and sodium transport. Am J Physiol Renal Physiol 311, F186-194, doi: 10. 1152/ajprenal. 00088. 2016 (2016).
    • (2016) Am J Physiol Renal Physiol , vol.311 , pp. F186-194
    • Ramkumar, N.1
  • 32
    • 0031040738 scopus 로고    scopus 로고
    • In vivo functional analysis of the Hoxa-1 3 retinoic acid response element (3RARE)
    • Dupe, V. et al. In vivo functional analysis of the Hoxa-1 3 retinoic acid response element (3RARE). Development 124, 399-410 (1997).
    • (1997) Development , vol.124 , pp. 399-410
    • Dupe, V.1
  • 33
    • 0037441645 scopus 로고    scopus 로고
    • Rapid generation of inducible mouse mutants
    • Seibler, J. et al. Rapid generation of inducible mouse mutants. Nucleic Acids Res 31, e12 (2003).
    • (2003) Nucleic Acids Res , vol.31 , pp. e12
    • Seibler, J.1
  • 34
    • 84888422103 scopus 로고    scopus 로고
    • Characterization and validation of cre-driver mouse lines
    • Gofflot, F. et al. Characterization and Validation of Cre-Driver Mouse Lines. Curr Protoc Mouse Biol 1, 1-15, doi: 10. 1002/9780470942390. mo100103 (2011).
    • (2011) Curr Protoc Mouse Biol , vol.1 , pp. 1-15
    • Gofflot, F.1
  • 35
    • 33644975004 scopus 로고    scopus 로고
    • RNA integrity and the effect on the real-time qRT-PCR performance
    • Fleige, S. & Pfaffl, M. W. RNA integrity and the effect on the real-time qRT-PCR performance. Mol Aspects Med 27, 126-139, doi: 10. 1016/j. mam. 2005. 12. 003 (2006).
    • (2006) Mol Aspects Med , vol.27 , pp. 126-139
    • Fleige, S.1    Pfaffl, M.W.2
  • 37
    • 33750475626 scopus 로고    scopus 로고
    • Quantitative real-time RT-PCR data analysis: Current concepts and the novel "gene expression's CT difference" formula
    • Schefe, J. H., Lehmann, K. E., Buschmann, I. R., Unger, T. & Funke-Kaiser, H. Quantitative real-time RT-PCR data analysis: current concepts and the novel "gene expression's CT difference" formula. J Mol Med (Berl) 84, 901-910, doi: 10. 1007/s00109-006-0097-6 (2006).
    • (2006) J Mol Med (Berl) , vol.84 , pp. 901-910
    • Schefe, J.H.1    Lehmann, K.E.2    Buschmann, I.R.3    Unger, T.4    Funke-Kaiser, H.5
  • 38
    • 34548817270 scopus 로고    scopus 로고
    • Toxicity of ligand-dependent Cre recombinases and generation of a conditional Cre deleter mouse allowing mosaic recombination in peripheral tissues
    • Hameyer, D. et al. Toxicity of ligand-dependent Cre recombinases and generation of a conditional Cre deleter mouse allowing mosaic recombination in peripheral tissues. Physiol Genomics 31, 32-41, doi: 10. 1152/physiolgenomics. 00019. 2007 (2007).
    • (2007) Physiol Genomics , vol.31 , pp. 32-41
    • Hameyer, D.1
  • 39
    • 0035029433 scopus 로고    scopus 로고
    • A highly efficient ligand-regulated Cre recombinase mouse line shows that LoxP recombination is position dependent
    • Vooijs, M., Jonkers, J. & Berns, A. A highly efficient ligand-regulated Cre recombinase mouse line shows that LoxP recombination is position dependent. EMBO Rep 2, 292-297, doi: 10. 1093/embo-reports/kve064 (2001).
    • (2001) EMBO Rep , vol.2 , pp. 292-297
    • Vooijs, M.1    Jonkers, J.2    Berns, A.3
  • 40
    • 11144358198 scopus 로고    scopus 로고
    • A gene atlas of the mouse and human protein-encoding transcriptomes
    • Su, A. I. et al. A gene atlas of the mouse and human protein-encoding transcriptomes. Proc Natl Acad Sci USA 101, 6062-6067, doi: 10. 1073/pnas. 0400782101 (2004).
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 6062-6067
    • Su, A.I.1
  • 41
    • 76249090489 scopus 로고    scopus 로고
    • BioGPS: An extensible and customizable portal for querying and organizing gene annotation resources
    • Wu, C. et al. BioGPS: an extensible and customizable portal for querying and organizing gene annotation resources. Genome Biol 10, R130, doi: 10. 1186/gb-2009-10-11-r130 (2009).
    • (2009) Genome Biol , vol.10 , pp. R130
    • Wu, C.1
  • 42
    • 84888434853 scopus 로고    scopus 로고
    • Immunological Genome Project and systems immunology
    • Shay, T. & Kang, J. Immunological Genome Project and systems immunology. Trends Immunol 34, 602-609, doi: 10. 1016/j. it. 2013. 03. 004 (2013).
    • (2013) Trends Immunol , vol.34 , pp. 602-609
    • Shay, T.1    Kang, J.2
  • 43
    • 40349093250 scopus 로고    scopus 로고
    • Histopathology in mouse metabolic investigations
    • Unit 29B 24
    • Mark, M. et al. Histopathology in mouse metabolic investigations. Curr Protoc Mol Biol Chapter 29, Unit 29B 24, doi: 10. 1002/0471142727. mb29b04s78 (2007).
    • (2007) Curr Protoc Mol Biol Chapter , vol.29
    • Mark, M.1
  • 44
    • 84904314069 scopus 로고    scopus 로고
    • Wnt some lose some: Transcriptional governance of stem cells by Wnt/beta-catenin signaling
    • Lien, W. H. & Fuchs, E. Wnt some lose some: transcriptional governance of stem cells by Wnt/beta-catenin signaling. Genes Dev 28, 1517-1532, doi: 10. 1101/gad. 244772. 114 (2014).
    • (2014) Genes Dev , vol.28 , pp. 1517-1532
    • Lien, W.H.1    Fuchs, E.2
  • 45
    • 84892938899 scopus 로고    scopus 로고
    • Comprehensive analysis of beta-catenin target genes in colorectal carcinoma cell lines with deregulated Wnt/betacatenin signaling
    • Herbst, A. et al. Comprehensive analysis of beta-catenin target genes in colorectal carcinoma cell lines with deregulated Wnt/betacatenin signaling. BMC Genomics 15, 74, doi: 10. 1186/1471-2164-15-74 (2014).
    • (2014) BMC Genomics , vol.15 , pp. 74
    • Herbst, A.1
  • 46
    • 79955681163 scopus 로고    scopus 로고
    • The intestinal stem cell signature identifies colorectal cancer stem cells and predicts disease relapse
    • Merlos-Suarez, A. et al. The intestinal stem cell signature identifies colorectal cancer stem cells and predicts disease relapse. Cell Stem Cell 8, 511-524, doi: 10. 1016/j. stem. 2011. 02. 020 (2011).
    • (2011) Cell Stem Cell , vol.8 , pp. 511-524
    • Merlos-Suarez, A.1
  • 47
    • 0037737728 scopus 로고    scopus 로고
    • A role for Wnt signalling in self-renewal of haematopoietic stem cells
    • Reya, T. et al. A role for Wnt signalling in self-renewal of haematopoietic stem cells. Nature 423, 409-414, doi: 10. 1038/nature01593 (2003).
    • (2003) Nature , vol.423 , pp. 409-414
    • Reya, T.1
  • 48
    • 32144449094 scopus 로고    scopus 로고
    • Aberrant crypt foci
    • Alrawi, S. J. et al. Aberrant crypt foci. Anticancer Res 26, 107-119 (2006).
    • (2006) Anticancer Res , vol.26 , pp. 107-119
    • Alrawi, S.J.1
  • 50
    • 58149478511 scopus 로고    scopus 로고
    • Aberrant crypt foci in colon cancer epidemiology
    • Khare, S., Chaudhary, K., Bissonnette, M. & Carroll, R. Aberrant crypt foci in colon cancer epidemiology. Methods Mol Biol 472, 373-386, doi: 10. 1007/978-1-60327-492-0-17 (2009).
    • (2009) Methods Mol Biol , vol.472 , pp. 373-386
    • Khare, S.1    Chaudhary, K.2    Bissonnette, M.3    Carroll, R.4
  • 51
    • 59049106578 scopus 로고    scopus 로고
    • Crypt stem cells as the cells-of-origin of intestinal cancer
    • Barker, N. et al. Crypt stem cells as the cells-of-origin of intestinal cancer. Nature 457, 608-611, doi: 10. 1038/nature07602 (2009).
    • (2009) Nature , vol.457 , pp. 608-611
    • Barker, N.1
  • 52
    • 0039964948 scopus 로고    scopus 로고
    • Renin-dependent cardiovascular functions and renin-independent blood-brain barrier functions revealed by renindeficient mice
    • Yanai, K. et al. Renin-dependent cardiovascular functions and renin-independent blood-brain barrier functions revealed by renindeficient mice. J Biol Chem 275, 5-8 (2000).
    • (2000) J Biol Chem , vol.275 , pp. 5-8
    • Yanai, K.1
  • 53
    • 0028152913 scopus 로고
    • Angiotensinogen-deficient mice with hypotension
    • Tanimoto, K. et al. Angiotensinogen-deficient mice with hypotension. J Biol Chem 269, 31334-31337 (1994).
    • (1994) J Biol Chem , vol.269 , pp. 31334-31337
    • Tanimoto, K.1
  • 54
    • 84855264059 scopus 로고    scopus 로고
    • Acute multiple organ failure in adult mice deleted for the developmental regulator Wt1
    • Chau, Y. Y. et al. Acute multiple organ failure in adult mice deleted for the developmental regulator Wt1. PLoS Genet 7, e1002404, doi: 10. 1371/journal. pgen. 1002404 (2011).
    • (2011) PLoS Genet , vol.7 , pp. e1002404
    • Chau, Y.Y.1
  • 55
    • 84892426577 scopus 로고    scopus 로고
    • The role of individual domains and the significance of shedding of ATP6AP2/(pro)renin receptor in vacuolar H(+)-ATPase biogenesis
    • Kinouchi, K. et al. The role of individual domains and the significance of shedding of ATP6AP2/(pro)renin receptor in vacuolar H(+)-ATPase biogenesis. PLoS One 8, e78603, doi: 10. 1371/journal. pone. 0078603 (2013).
    • (2013) PLoS One , vol.8 , pp. e78603
    • Kinouchi, K.1
  • 56
    • 67049144916 scopus 로고    scopus 로고
    • Soluble form of the (pro)renin receptor generated by intracellular cleavage by furin is secreted in plasma
    • Cousin, C. et al. Soluble form of the (pro)renin receptor generated by intracellular cleavage by furin is secreted in plasma. Hypertension 53, 1077-1082, doi: 10. 1161/HYPERTENSIONAHA. 108. 127258 (2009).
    • (2009) Hypertension , vol.53 , pp. 1077-1082
    • Cousin, C.1
  • 57
    • 77749239824 scopus 로고    scopus 로고
    • Possible roles of human (pro)renin receptor suggested by recent clinical and experimental findings
    • Ichihara, A. et al. Possible roles of human (pro)renin receptor suggested by recent clinical and experimental findings. Hypertens Res 33, 177-180, doi: 10. 1038/hr. 2009. 214 (2010).
    • (2010) Hypertens Res , vol.33 , pp. 177-180
    • Ichihara, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.