Conditional depletion of intellectual disability and Parkinsonism candidate gene ATP6AP2 in fly and mouse induces cognitive impairment and neurodegeneration

Human Molecular Genetics

Volumn 24, Issue 23, 2015, Pages 6736-6755

  Dubos, Aline ^a,i,j,k   Castells Nobau, Anna ^b   Meziane, Hamid ^a   Oortveld, Merel A W ^b   Houbaert, Xander ^c   Iacono, Giovanni ^d   Martin, Christelle ^c   Mittelhaeuser, Christophe ^a   Lalanne, Valérie ^a   Kramer, Jamie M ^b   Bhukel, Anuradha ^e   Quentin, Christine ^e,f   Slabbert, Jan ^g,h   Verstreken, Patrik ^g,h   Sigrist, Stefan J ^e,f   Messaddeq, Nadia ^i,j,k   Birling, Marie Christine ^a   Selloum, Mohammed ^a   Stunnenberg, Henk G ^d   Humeau, Yann ^c   Schenck, Annette ^b   Herault, Yann ^a,i,j,k   more..

^a INSTITUT CLINIQUE DE LA SOURIS   (France)

^b RADBOUD UNIVERSITY   (Netherlands)

^c University of Bordeaux   (France)

^d RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^e FREIE UNIVERSITÄT BERLIN   (Germany)

^f CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^g DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^h UNIVERSITY OF LEUVEN   (Belgium)

ⁱ INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^j CNRS   (France)

^k UNIVERSITÉ DE STRASBOURG   (France)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATP6AP2 GENE; BEHAVIOR ASSESSMENT; DEPLETION; DIPTERA; DROSOPHILA; ELECTROENCEPHALOGRAPHY; ELECTRON MICROSCOPY; ELECTROPHYSIOLOGY; ELECTRORETINOGRAM; FEMALE; GENE; GENE KNOCKDOWN; HISTOLOGY; IMMUNODETECTION; IMMUNOHISTOCHEMISTRY; INTELLECTUAL IMPAIRMENT; LOCOMOTION; LONG TERM MEMORY; MALE; MOUSE; MUSHROOM BODY; NERVE DEGENERATION; NEUROLOGIC EXAMINATION; NEUROPATHOLOGY; NEUROTRANSMISSION; NONHUMAN; NOVEL OBJECT RECOGNITION TEST; PARKINSONISM; PHENOTYPE; PHOTORECEPTOR; PHOTOTAXIS; PIGMENT CELL; REAL TIME POLYMERASE CHAIN REACTION; RNA SEQUENCING; SHORT TERM MEMORY; SOCIAL RECOGNITION TEST; SYNAPTIC TRANSMISSION; ANIMAL; BRAIN; COGNITION DISORDERS; DISEASE MODEL; GENE SILENCING; GENETICS; METABOLISM; NERVE CELL; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SYNAPSE; ULTRASTRUCTURE;

ATP6AP2 PROTEIN, MOUSE; CELL SURFACE RECEPTOR; DROSOPHILA PROTEIN; MEMBRANE PROTEIN; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATASE; VHAPRR PROTEIN, DROSOPHILA;

ANIMALS; BRAIN; COGNITION DISORDERS; DISEASE MODELS, ANIMAL; DROSOPHILA; DROSOPHILA PROTEINS; FEMALE; GENE KNOCKDOWN TECHNIQUES; INTELLECTUAL DISABILITY; MALE; MEMBRANE PROTEINS; MICE; NERVE DEGENERATION; NEURONS; PARKINSONIAN DISORDERS; PROTON-TRANSLOCATING ATPASES; RECEPTORS, CELL SURFACE; SYNAPSES;

EID: 84958709411     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddv380     Document Type: Article

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