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Volumn 34, Issue , 2017, Pages 61-67

Drug nanocarriers to treat autoimmunity and chronic inflammatory diseases

Author keywords

Autoimmune diseases; Dendritic cells; Inflammatory diseases; Innate immune cells; Macrophages; Nanomedicine; Nanoparticles

Indexed keywords

NANOCARRIER; NANOPARTICLE;

EID: 85028365308     PISSN: 10445323     EISSN: 10963618     Source Type: Journal    
DOI: 10.1016/j.smim.2017.08.010     Document Type: Review
Times cited : (75)

References (79)
  • 1
    • 14644439267 scopus 로고    scopus 로고
    • Cancer nanotechnology: opportunities and challenges
    • Ferrari, M., Cancer nanotechnology: opportunities and challenges. Nat. Rev. Cancer 5 (2005), 161–171.
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 161-171
    • Ferrari, M.1
  • 3
    • 84915749562 scopus 로고    scopus 로고
    • Editorial: are we entering the nano era?
    • Xia, Y., Editorial: are we entering the nano era?. Angew. Chem. Int. Ed. Engl. 53 (2014), 12268–12271.
    • (2014) Angew. Chem. Int. Ed. Engl. , vol.53 , pp. 12268-12271
    • Xia, Y.1
  • 4
    • 79959784406 scopus 로고    scopus 로고
    • Nanoparticle therapeutics: FDA approval, clinical trials, regulatory pathways, and case study
    • Eifler, A.C., Thaxton, C.S., Nanoparticle therapeutics: FDA approval, clinical trials, regulatory pathways, and case study. Methods Mol. Biol. 726 (2011), 325–338.
    • (2011) Methods Mol. Biol. , vol.726 , pp. 325-338
    • Eifler, A.C.1    Thaxton, C.S.2
  • 5
    • 51049090204 scopus 로고    scopus 로고
    • Nanoparticle therapeutics: an emerging treatment modality for cancer
    • Davis, M.E., Chen, Z.G., Shin, D.M., Nanoparticle therapeutics: an emerging treatment modality for cancer. Nat. Rev. Drug Discov. 7 (2008), 771–782.
    • (2008) Nat. Rev. Drug Discov. , vol.7 , pp. 771-782
    • Davis, M.E.1    Chen, Z.G.2    Shin, D.M.3
  • 7
    • 74449092896 scopus 로고    scopus 로고
    • Silencing of proinflammatory genes targeted to peritoneal-residing macrophages using siRNA encapsulated in biodegradable microspheres
    • Brunner, T., Cohen, S., Monsonego, A., Silencing of proinflammatory genes targeted to peritoneal-residing macrophages using siRNA encapsulated in biodegradable microspheres. Biomaterials 31 (2010), 2627–2636.
    • (2010) Biomaterials , vol.31 , pp. 2627-2636
    • Brunner, T.1    Cohen, S.2    Monsonego, A.3
  • 8
    • 38349154138 scopus 로고    scopus 로고
    • Nano/micro technologies for delivering macromolecular therapeutics using poly(D,L-lactide-co-glycolide) and its derivatives
    • Mundargi, R.C., Babu, V.R., Rangaswamy, V., Patel, P., Aminabhavi, T.M., Nano/micro technologies for delivering macromolecular therapeutics using poly(D,L-lactide-co-glycolide) and its derivatives. J. Control. Release 125 (2008), 193–209.
    • (2008) J. Control. Release , vol.125 , pp. 193-209
    • Mundargi, R.C.1    Babu, V.R.2    Rangaswamy, V.3    Patel, P.4    Aminabhavi, T.M.5
  • 10
    • 84864140479 scopus 로고    scopus 로고
    • Engineering nano- and microparticles to tune immunity
    • Moon, J.J., Huang, B., Irvine, D.J., Engineering nano- and microparticles to tune immunity. Adv. Mater. 24 (2012), 3724–3746.
    • (2012) Adv. Mater. , vol.24 , pp. 3724-3746
    • Moon, J.J.1    Huang, B.2    Irvine, D.J.3
  • 13
    • 84864385195 scopus 로고    scopus 로고
    • Updated assessment of the prevalence, spectrum and case definition of autoimmune disease
    • Hayter, S.M., Cook, M.C., Updated assessment of the prevalence, spectrum and case definition of autoimmune disease. Autoimmun. Rev. 11 (2012), 754–765.
    • (2012) Autoimmun. Rev. , vol.11 , pp. 754-765
    • Hayter, S.M.1    Cook, M.C.2
  • 14
    • 0024955886 scopus 로고
    • Approaching the asymptote? Evolution and revolution in immunology
    • Janeway, C.A. Jr., Approaching the asymptote? Evolution and revolution in immunology. Cold Spring Harb. Symp. Quant. Biol. 54:Pt. 1 (1989), 1–13.
    • (1989) Cold Spring Harb. Symp. Quant. Biol. , vol.54 , pp. 1-13
    • Janeway, C.A.1
  • 15
    • 84927639135 scopus 로고    scopus 로고
    • Innate immune pattern recognition: a cell biological perspective
    • Brubaker, S.W., Bonham, K.S., Zanoni, I., Kagan, J.C., Innate immune pattern recognition: a cell biological perspective. Annu. Rev. Immunol. 33 (2015), 257–290.
    • (2015) Annu. Rev. Immunol. , vol.33 , pp. 257-290
    • Brubaker, S.W.1    Bonham, K.S.2    Zanoni, I.3    Kagan, J.C.4
  • 16
    • 84856655642 scopus 로고    scopus 로고
    • Targeted nanotherapy for induction of therapeutic immune responses
    • Metcalfe, S.M., Fahmy, T.M., Targeted nanotherapy for induction of therapeutic immune responses. Trends Mol. Med. 18 (2012), 72–80.
    • (2012) Trends Mol. Med. , vol.18 , pp. 72-80
    • Metcalfe, S.M.1    Fahmy, T.M.2
  • 17
    • 84864297173 scopus 로고    scopus 로고
    • Microparticle surface modifications targeting dendritic cells for non-activating applications
    • Lewis, J.S., Zaveri, T.D., Crooks, C.P. 2nd, Keselowsky, B.G., Microparticle surface modifications targeting dendritic cells for non-activating applications. Biomaterials 33 (2012), 7221–7232.
    • (2012) Biomaterials , vol.33 , pp. 7221-7232
    • Lewis, J.S.1    Zaveri, T.D.2    Crooks, C.P.3    Keselowsky, B.G.4
  • 19
    • 0029559927 scopus 로고
    • Molecular mechanisms of immunosuppression by cyclosporine, FK506, and rapamycin
    • Cardenas, M.E., Zhu, D., Heitman, J., Molecular mechanisms of immunosuppression by cyclosporine, FK506, and rapamycin. Curr. Opin. Nephrol. Hypertens. 4 (1995), 472–477.
    • (1995) Curr. Opin. Nephrol. Hypertens. , vol.4 , pp. 472-477
    • Cardenas, M.E.1    Zhu, D.2    Heitman, J.3
  • 21
    • 78049288264 scopus 로고    scopus 로고
    • Vaccine delivery: a matter of size, geometry, kinetics and molecular patterns
    • Bachmann, M.F., Jennings, G.T., Vaccine delivery: a matter of size, geometry, kinetics and molecular patterns. Nat. Rev. Immunol. 10 (2010), 787–796.
    • (2010) Nat. Rev. Immunol. , vol.10 , pp. 787-796
    • Bachmann, M.F.1    Jennings, G.T.2
  • 23
    • 84863949288 scopus 로고    scopus 로고
    • Nanoparticle-mediated codelivery of myelin antigen and a tolerogenic small molecule suppresses experimental autoimmune encephalomyelitis
    • Yeste, A., Nadeau, M., Burns, E.J., Weiner, H.L., Quintana, F.J., Nanoparticle-mediated codelivery of myelin antigen and a tolerogenic small molecule suppresses experimental autoimmune encephalomyelitis. Proc. Natl. Acad. Sci. U. S. A. 109 (2012), 11270–11275.
    • (2012) Proc. Natl. Acad. Sci. U. S. A. , vol.109 , pp. 11270-11275
    • Yeste, A.1    Nadeau, M.2    Burns, E.J.3    Weiner, H.L.4    Quintana, F.J.5
  • 28
    • 84930162556 scopus 로고    scopus 로고
    • Paracrine co-delivery of TGF-beta and IL-2 using CD4-targeted NPs for induction and maintenance of regulatory T cells
    • McHugh, M.D., Park, J., Uhrich, R., Gao, W., Horwitz, D.A., Fahmy, T.M., Paracrine co-delivery of TGF-beta and IL-2 using CD4-targeted NPs for induction and maintenance of regulatory T cells. Biomaterials 59 (2015), 172–181.
    • (2015) Biomaterials , vol.59 , pp. 172-181
    • McHugh, M.D.1    Park, J.2    Uhrich, R.3    Gao, W.4    Horwitz, D.A.5    Fahmy, T.M.6
  • 29
    • 34248136828 scopus 로고    scopus 로고
    • Inflammatory bowel disease: cause and immunobiology
    • Baumgart, D.C., Carding, S.R., Inflammatory bowel disease: cause and immunobiology. Lancet 369 (2007), 1627–1640.
    • (2007) Lancet , vol.369 , pp. 1627-1640
    • Baumgart, D.C.1    Carding, S.R.2
  • 30
    • 34248136340 scopus 로고    scopus 로고
    • Inflammatory bowel disease: clinical aspects and established and evolving therapies
    • Baumgart, D.C., Sandborn, W.J., Inflammatory bowel disease: clinical aspects and established and evolving therapies. Lancet 369 (2007), 1641–1657.
    • (2007) Lancet , vol.369 , pp. 1641-1657
    • Baumgart, D.C.1    Sandborn, W.J.2
  • 32
    • 84977591302 scopus 로고    scopus 로고
    • NPs for oral delivery: design, evaluation and state-of-the-art
    • Date, A.A., Hanes, J., Ensign, L.M., NPs for oral delivery: design, evaluation and state-of-the-art. J. Control. Release 240 (2016), 504–526.
    • (2016) J. Control. Release , vol.240 , pp. 504-526
    • Date, A.A.1    Hanes, J.2    Ensign, L.M.3
  • 33
    • 84942304401 scopus 로고    scopus 로고
    • Intestinal epithelium in inflammatory bowel disease
    • Coskun, M., Intestinal epithelium in inflammatory bowel disease. Front. Med., 1, 2014, 24.
    • (2014) Front. Med. , vol.1 , pp. 24
    • Coskun, M.1
  • 35
    • 52049084593 scopus 로고    scopus 로고
    • The targeting of surface modified silica NPs to inflamed tissue in experimental colitis
    • Moulari, B., Pertuit, D., Pellequer, Y., Lamprecht, A., The targeting of surface modified silica NPs to inflamed tissue in experimental colitis. Biomaterials 29 (2008), 4554–4560.
    • (2008) Biomaterials , vol.29 , pp. 4554-4560
    • Moulari, B.1    Pertuit, D.2    Pellequer, Y.3    Lamprecht, A.4
  • 37
    • 77958494386 scopus 로고    scopus 로고
    • Orally delivered thioketal NPs loaded with TNF-alpha-siRNA target inflammation and inhibit gene expression in the intestines
    • Wilson, D.S., Dalmasso, G., Wang, L., Sitaraman, S.V., Merlin, D., Murthy, N., Orally delivered thioketal NPs loaded with TNF-alpha-siRNA target inflammation and inhibit gene expression in the intestines. Nat. Mater. 9 (2010), 923–928.
    • (2010) Nat. Mater. , vol.9 , pp. 923-928
    • Wilson, D.S.1    Dalmasso, G.2    Wang, L.3    Sitaraman, S.V.4    Merlin, D.5    Murthy, N.6
  • 38
    • 78649445973 scopus 로고    scopus 로고
    • Functional TNFalpha gene silencing mediated by polyethyleneimine/TNFalpha siRNA nanocomplexes in inflamed colon
    • Laroui, H., Theiss, A.L., Yan, Y., Dalmasso, G., Nguyen, H.T., Sitaraman, S.V., Merlin, D., Functional TNFalpha gene silencing mediated by polyethyleneimine/TNFalpha siRNA nanocomplexes in inflamed colon. Biomaterials 32 (2011), 1218–1228.
    • (2011) Biomaterials , vol.32 , pp. 1218-1228
    • Laroui, H.1    Theiss, A.L.2    Yan, Y.3    Dalmasso, G.4    Nguyen, H.T.5    Sitaraman, S.V.6    Merlin, D.7
  • 39
    • 29244442282 scopus 로고    scopus 로고
    • Formulation optimization for the NPs-in-microsphere hybrid oral delivery system using factorial design
    • Bhavsar, M.D., Tiwari, S.B., Amiji, M.M., Formulation optimization for the NPs-in-microsphere hybrid oral delivery system using factorial design. J. Control. Release 110 (2006), 422–430.
    • (2006) J. Control. Release , vol.110 , pp. 422-430
    • Bhavsar, M.D.1    Tiwari, S.B.2    Amiji, M.M.3
  • 40
    • 84878880199 scopus 로고    scopus 로고
    • Multi-compartmental oral delivery systems for nucleic acid therapy in the gastrointestinal tract
    • Kriegel, C., Attarwala, H., Amiji, M., Multi-compartmental oral delivery systems for nucleic acid therapy in the gastrointestinal tract. Adv. Drug Deliv. Rev. 65 (2013), 891–901.
    • (2013) Adv. Drug Deliv. Rev. , vol.65 , pp. 891-901
    • Kriegel, C.1    Attarwala, H.2    Amiji, M.3
  • 41
    • 34248676278 scopus 로고    scopus 로고
    • Gastrointestinal distribution and in vivo gene transfection studies with NPs-in-microsphere oral system (NiMOS)
    • Bhavsar, M.D., Amiji, M.M., Gastrointestinal distribution and in vivo gene transfection studies with NPs-in-microsphere oral system (NiMOS). J. Control. Release 119 (2007), 339–348.
    • (2007) J. Control. Release , vol.119 , pp. 339-348
    • Bhavsar, M.D.1    Amiji, M.M.2
  • 42
    • 44849127344 scopus 로고    scopus 로고
    • Development of novel biodegradable polymeric NPs-in-microsphere formulation for local plasmid DNA delivery in the gastrointestinal tract
    • Bhavsar, M.D., Amiji, M.M., Development of novel biodegradable polymeric NPs-in-microsphere formulation for local plasmid DNA delivery in the gastrointestinal tract. AAPS PharmSciTech 9 (2008), 288–294.
    • (2008) AAPS PharmSciTech , vol.9 , pp. 288-294
    • Bhavsar, M.D.1    Amiji, M.M.2
  • 43
    • 79951955176 scopus 로고    scopus 로고
    • Oral TNF-alpha gene silencing using a polymeric microsphere-based delivery system for the treatment of inflammatory bowel disease
    • Kriegel, C., Amiji, M., Oral TNF-alpha gene silencing using a polymeric microsphere-based delivery system for the treatment of inflammatory bowel disease. J. Control. Release 150 (2011), 77–86.
    • (2011) J. Control. Release , vol.150 , pp. 77-86
    • Kriegel, C.1    Amiji, M.2
  • 44
    • 25644442467 scopus 로고    scopus 로고
    • NPs enhance therapeutic efficiency by selectively increased local drug dose in experimental colitis in rats
    • Lamprecht, A., Yamamoto, H., Takeuchi, H., Kawashima, Y., NPs enhance therapeutic efficiency by selectively increased local drug dose in experimental colitis in rats. J. Pharmacol. Exp. Ther. 315 (2005), 196–202.
    • (2005) J. Pharmacol. Exp. Ther. , vol.315 , pp. 196-202
    • Lamprecht, A.1    Yamamoto, H.2    Takeuchi, H.3    Kawashima, Y.4
  • 45
    • 19444381516 scopus 로고    scopus 로고
    • A pH-sensitive microsphere system for the colon delivery of tacrolimus containing NPs
    • Lamprecht, A., Yamamoto, H., Takeuchi, H., Kawashima, Y., A pH-sensitive microsphere system for the colon delivery of tacrolimus containing NPs. J. Control. Release 104 (2005), 337–346.
    • (2005) J. Control. Release , vol.104 , pp. 337-346
    • Lamprecht, A.1    Yamamoto, H.2    Takeuchi, H.3    Kawashima, Y.4
  • 47
    • 84888389605 scopus 로고    scopus 로고
    • PEG-functionalized microparticles selectively target inflamed mucosa in inflammatory bowel disease
    • Lautenschlager, C., Schmidt, C., Lehr, C.M., Fischer, D., Stallmach, A., PEG-functionalized microparticles selectively target inflamed mucosa in inflammatory bowel disease. Eur. J. Pharm. Biopharm. 85 (2013), 578–586.
    • (2013) Eur. J. Pharm. Biopharm. , vol.85 , pp. 578-586
    • Lautenschlager, C.1    Schmidt, C.2    Lehr, C.M.3    Fischer, D.4    Stallmach, A.5
  • 49
    • 84923093767 scopus 로고    scopus 로고
    • T cell responses in psoriasis and psoriatic arthritis
    • Diani, M., Altomare, G., Reali, E., T cell responses in psoriasis and psoriatic arthritis. Autoimmun. Rev. 14 (2015), 286–292.
    • (2015) Autoimmun. Rev. , vol.14 , pp. 286-292
    • Diani, M.1    Altomare, G.2    Reali, E.3
  • 50
    • 85035084559 scopus 로고    scopus 로고
    • Cardiovascular morbidity and mortality of cutaneous psoriasis (PsC) and psoriatic arthritis (PsA) are well documented, with increased risks of myocardial infarction, ischemic heart disease, and the metabolic syndrome in these patients
    • Chung, Y., Eder, L., Chandran, V., Gladman, D., Cardiovascular morbidity and mortality of cutaneous psoriasis (PsC) and psoriatic arthritis (PsA) are well documented, with increased risks of myocardial infarction, ischemic heart disease, and the metabolic syndrome in these patients. J. Rheumatol. 42 (2015), 1344–1345.
    • (2015) J. Rheumatol. , vol.42 , pp. 1344-1345
    • Chung, Y.1    Eder, L.2    Chandran, V.3    Gladman, D.4
  • 51
    • 84876816203 scopus 로고    scopus 로고
    • IL-17 in psoriasis: implications for therapy and cardiovascular co-morbidities
    • Golden, J.B., McCormick, T.S., Ward, N.L., IL-17 in psoriasis: implications for therapy and cardiovascular co-morbidities. Cytokine 62 (2013), 195–201.
    • (2013) Cytokine , vol.62 , pp. 195-201
    • Golden, J.B.1    McCormick, T.S.2    Ward, N.L.3
  • 52
    • 84856017799 scopus 로고    scopus 로고
    • Cardiovascular and other comorbidities in patients with psoriatic arthritis: a comparison with patients with psoriasis
    • Husted, J.A., Thavaneswaran, A., Chandran, V., Eder, L., Rosen, C.F., Cook, R.J., Gladman, D.D., Cardiovascular and other comorbidities in patients with psoriatic arthritis: a comparison with patients with psoriasis. Arthritis Care Res. 63 (2011), 1729–1735.
    • (2011) Arthritis Care Res. , vol.63 , pp. 1729-1735
    • Husted, J.A.1    Thavaneswaran, A.2    Chandran, V.3    Eder, L.4    Rosen, C.F.5    Cook, R.J.6    Gladman, D.D.7
  • 56
    • 84866330023 scopus 로고    scopus 로고
    • Nanocarrier-based hydrogel of betamethasone dipropionate and salicylic acid for treatment of psoriasis
    • Baboota, S., Alam, M.S., Sharma, S., Sahni, J.K., Kumar, A., Ali, J., Nanocarrier-based hydrogel of betamethasone dipropionate and salicylic acid for treatment of psoriasis. Int. J. Pharm. Invest. 1 (2011), 139–147.
    • (2011) Int. J. Pharm. Invest. , vol.1 , pp. 139-147
    • Baboota, S.1    Alam, M.S.2    Sharma, S.3    Sahni, J.K.4    Kumar, A.5    Ali, J.6
  • 57
    • 80052588682 scopus 로고    scopus 로고
    • Microparticulate based topical delivery system of clobetasol propionate
    • Badilli, U., Sen, T., Tarimci, N., Microparticulate based topical delivery system of clobetasol propionate. AAPS PharmSciTech 12 (2011), 949–957.
    • (2011) AAPS PharmSciTech , vol.12 , pp. 949-957
    • Badilli, U.1    Sen, T.2    Tarimci, N.3
  • 58
    • 2442622597 scopus 로고    scopus 로고
    • Hydrocortisone and dexamethasone in very deformable drug carriers have increased biological potency, prolonged effect, and reduced therapeutic dosage
    • Cevc, G., Blume, G., Hydrocortisone and dexamethasone in very deformable drug carriers have increased biological potency, prolonged effect, and reduced therapeutic dosage. BBA–Biomembranes 1663 (2004), 61–73.
    • (2004) BBA–Biomembranes , vol.1663 , pp. 61-73
    • Cevc, G.1    Blume, G.2
  • 59
    • 0025114527 scopus 로고
    • Liposome encapsulation improves efficacy of betamethasone dipropionate in atopic eczema but not in psoriasis-vulgaris
    • Korting, H.C., Zienicke, H., Schaferkorting, M., Braunfalco, O., Liposome encapsulation improves efficacy of betamethasone dipropionate in atopic eczema but not in psoriasis-vulgaris. Eur. J. Clin. Pharmacol. 39 (1990), 349–351.
    • (1990) Eur. J. Clin. Pharmacol. , vol.39 , pp. 349-351
    • Korting, H.C.1    Zienicke, H.2    Schaferkorting, M.3    Braunfalco, O.4
  • 60
    • 79251551386 scopus 로고    scopus 로고
    • Percutaneous permeation of betamethasone 17-valerate incorporated in lipid NPs
    • Zhang, J., Smith, E., Percutaneous permeation of betamethasone 17-valerate incorporated in lipid NPs. J. Pharm. Sci. 100 (2011), 896–903.
    • (2011) J. Pharm. Sci. , vol.100 , pp. 896-903
    • Zhang, J.1    Smith, E.2
  • 61
    • 77951186087 scopus 로고    scopus 로고
    • Combination of calcipotriol and methotrexate in nanostructured lipid carriers for topical delivery
    • Lin, Y.K., Huang, Z.R., Zhuo, R.Z., Fang, J.Y., Combination of calcipotriol and methotrexate in nanostructured lipid carriers for topical delivery. Int. J. Nanomed. 5 (2010), 117–128.
    • (2010) Int. J. Nanomed. , vol.5 , pp. 117-128
    • Lin, Y.K.1    Huang, Z.R.2    Zhuo, R.Z.3    Fang, J.Y.4
  • 62
    • 85001976365 scopus 로고    scopus 로고
    • Solid lipid NPs and nanostructured lipid carrier-based nanotherapeutics in treatment of psoriasis: a comparative study
    • Arora, R., Katiyar, S.S., Kushwah, V., Jain, S., Solid lipid NPs and nanostructured lipid carrier-based nanotherapeutics in treatment of psoriasis: a comparative study. Expert Opin. Drug Deliv. 14 (2017), 165–177.
    • (2017) Expert Opin. Drug Deliv. , vol.14 , pp. 165-177
    • Arora, R.1    Katiyar, S.S.2    Kushwah, V.3    Jain, S.4
  • 63
    • 85014344841 scopus 로고    scopus 로고
    • Effects of NPs with hydrotropic nicotinamide on tacrolimus: permeability through psoriatic skin and antipsoriatic and antiproliferative activities
    • Wan, T., Pan, W., Long, Y., Yu, K., Liu, S., Ruan, W., Pan, J., Qin, M., Wu, C., Xu, Y., Effects of NPs with hydrotropic nicotinamide on tacrolimus: permeability through psoriatic skin and antipsoriatic and antiproliferative activities. Int. J. Nanomed. 12 (2017), 1485–1497.
    • (2017) Int. J. Nanomed. , vol.12 , pp. 1485-1497
    • Wan, T.1    Pan, W.2    Long, Y.3    Yu, K.4    Liu, S.5    Ruan, W.6    Pan, J.7    Qin, M.8    Wu, C.9    Xu, Y.10
  • 64
    • 57349096426 scopus 로고    scopus 로고
    • Liposomal methotrexate hydrogel for treatment of localized psoriasis: preparation, characterization and laser targeting
    • Ali, M.F.M., Salah, M., Rafea, M., Saleh, N., Liposomal methotrexate hydrogel for treatment of localized psoriasis: preparation, characterization and laser targeting. Med. Sci. Monit. 14 (2008), Pi66–Pi74.
    • (2008) Med. Sci. Monit. , vol.14 , pp. Pi66-Pi74
    • Ali, M.F.M.1    Salah, M.2    Rafea, M.3    Saleh, N.4
  • 65
    • 34250310393 scopus 로고    scopus 로고
    • Niosomal methotrexate gel in the treatment of localized psoriasis: phase I and phase II studies
    • Lakshmi, P.K., Devi, G.S., Bhaskaran, S., Sacchidanand, S., Niosomal methotrexate gel in the treatment of localized psoriasis: phase I and phase II studies. Indian J. Dermatol. Venereol. Leprol. 73 (2007), 157–161.
    • (2007) Indian J. Dermatol. Venereol. Leprol. , vol.73 , pp. 157-161
    • Lakshmi, P.K.1    Devi, G.S.2    Bhaskaran, S.3    Sacchidanand, S.4
  • 66
    • 0345761185 scopus 로고    scopus 로고
    • Deformable liposomes for dermal administration of methotrexate
    • Trotta, M., Peira, E., Carlotti, M.E., Gallarate, M., Deformable liposomes for dermal administration of methotrexate. Int. J. Pharm. 270 (2004), 119–125.
    • (2004) Int. J. Pharm. , vol.270 , pp. 119-125
    • Trotta, M.1    Peira, E.2    Carlotti, M.E.3    Gallarate, M.4
  • 67
    • 0037173516 scopus 로고    scopus 로고
    • Elastic liposomes for skin delivery of dipotassium glycyrrhizinate
    • Trotta, M., Peira, E., Debernardi, F., Gallarate, M., Elastic liposomes for skin delivery of dipotassium glycyrrhizinate. Int. J. Pharm. 241 (2002), 319–327.
    • (2002) Int. J. Pharm. , vol.241 , pp. 319-327
    • Trotta, M.1    Peira, E.2    Debernardi, F.3    Gallarate, M.4
  • 68
    • 0025304539 scopus 로고
    • Rheumatoid arthritis. Pathophysiology and implications for therapy
    • Harris, E.D. Jr., Rheumatoid arthritis. Pathophysiology and implications for therapy. N. Engl. J. Med. 322 (1990), 1277–1289.
    • (1990) N. Engl. J. Med. , vol.322 , pp. 1277-1289
    • Harris, E.D.1
  • 69
    • 0034993240 scopus 로고    scopus 로고
    • The enhanced permeability and retention (EPR) effect in tumor vasculature: the key role of tumor-selective macromolecular drug targeting
    • Maeda, H., The enhanced permeability and retention (EPR) effect in tumor vasculature: the key role of tumor-selective macromolecular drug targeting. Adv. Enzyme Regul. 41 (2001), 189–207.
    • (2001) Adv. Enzyme Regul. , vol.41 , pp. 189-207
    • Maeda, H.1
  • 71
    • 0038002438 scopus 로고    scopus 로고
    • Complete remission of experimental arthritis by joint targeting of glucocorticoids with long-circulating liposomes
    • Metselaar, J.M., Wauben, M.H.M., Wagenaar-Hilbers, J.P.A., Boerman, O.C., Storm, G., Complete remission of experimental arthritis by joint targeting of glucocorticoids with long-circulating liposomes. Arthritis Rheum. 48 (2003), 2059–2066.
    • (2003) Arthritis Rheum. , vol.48 , pp. 2059-2066
    • Metselaar, J.M.1    Wauben, M.H.M.2    Wagenaar-Hilbers, J.P.A.3    Boerman, O.C.4    Storm, G.5
  • 75
    • 84872870773 scopus 로고    scopus 로고
    • Targeted chemo-photothermal treatments of rheumatoid arthritis using gold half-shell multifunctional NPs
    • Lee, S.M., Kim, H.J., Ha, Y.J., Park, Y.N., Lee, S.K., Park, Y.B., Yoo, K.H., Targeted chemo-photothermal treatments of rheumatoid arthritis using gold half-shell multifunctional NPs. ACS Nano 7 (2013), 50–57.
    • (2013) ACS Nano , vol.7 , pp. 50-57
    • Lee, S.M.1    Kim, H.J.2    Ha, Y.J.3    Park, Y.N.4    Lee, S.K.5    Park, Y.B.6    Yoo, K.H.7
  • 78
    • 3042698264 scopus 로고    scopus 로고
    • Methotrexate (MTX) and albumin coupled with MTX (MTX-HSA) suppress synovial fibroblast invasion and cartilage degradation in vivo
    • Fiehn, C., Neumann, E., Wunder, A., Krienke, S., Gay, S., Muller-Ladner, U., Methotrexate (MTX) and albumin coupled with MTX (MTX-HSA) suppress synovial fibroblast invasion and cartilage degradation in vivo. Ann. Rheum. Dis. 63 (2004), 884–886.
    • (2004) Ann. Rheum. Dis. , vol.63 , pp. 884-886
    • Fiehn, C.1    Neumann, E.2    Wunder, A.3    Krienke, S.4    Gay, S.5    Muller-Ladner, U.6
  • 79
    • 84949571103 scopus 로고    scopus 로고
    • Pharmaceutical potential of tacrolimus-loaded albumin NPs having targetability to rheumatoid arthritis tissues
    • Thao, L.Q., Byeon, H.J., Lee, C., Lee, S., Lee, E.S., Choi, H.G., Park, E.S., Youn, Y.S., Pharmaceutical potential of tacrolimus-loaded albumin NPs having targetability to rheumatoid arthritis tissues. Int. J. Pharm. 497 (2016), 268–276.
    • (2016) Int. J. Pharm. , vol.497 , pp. 268-276
    • Thao, L.Q.1    Byeon, H.J.2    Lee, C.3    Lee, S.4    Lee, E.S.5    Choi, H.G.6    Park, E.S.7    Youn, Y.S.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.