Liposomal Methotrexate hydrogel for treatment of localized psoriasis: Preparation, characterization and laser targeting

Medical Science Monitor

Volumn 14, Issue 12, 2008, Pages

  Ali, Maha Fadel Mohamed ^a   Salah, Manal ^a   Rafea, Maha ^a   Saleh, Nadia ^b  

^a Cairo University   (Egypt)

^b CAIRO UNIVERSITY   (Egypt)

Author keywords

Diode laser; Hydrogel; Liposomes; Methotrexate; Psoriasis

Indexed keywords

LIPOSOME; METHOTREXATE; PLACEBO;

ADULT; AGED; ANIMAL EXPERIMENT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DIODE LASER; DRUG DOSAGE FORM COMPARISON; DRUG EFFICACY; DRUG FORMULATION; DRUG RELEASE; DRUG WITHDRAWAL; ENCAPSULATION; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; HYDROGEL; LASER; MALE; MOUSE; NONHUMAN; PSORIASIS; PSORIASIS VULGARIS; SKIN IRRITATION; SKIN PERMEABILITY; THERMAL ANALYSIS; TREATMENT RESPONSE;

ADMINISTRATION, TOPICAL; ADOLESCENT; ADULT; AGED; ANIMALS; DOUBLE-BLIND METHOD; FEMALE; HUMANS; HYDROGELS; IMMUNOSUPPRESSIVE AGENTS; LIPOSOMES; MALE; METHOTREXATE; MICE; MIDDLE AGED; PLACEBOS; PSORIASIS;

EID: 57349096426     PISSN: 12341010     EISSN: 16433750     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Lotti TM, Delescluse J, Hercogova J: Established treatment for psoriasis. A critical review. Inter J Immunopath Pharmacol, 2001; 13: 1-6
2. Weinstein GD, McCullough JL, Olsen E: Topical methotrexate therapy for psoriasis. Arch Dermatol, 1989; 125: 227-30
3. Eskicirak B, Zemberi E, Cerkezoglu A: The treatment of psoriasis vulgaris: 1% topical methotrexate gel. Int J dermatol, 2006; 45(8): 965-69
4. Kumar B, Sandhu K, Kaur I: Topical 0.25% methotrexate gel in a hydrogel base for palmoplantar Psoriasis. J Dermatol, 2004; 31(10): 798-801
5. Avarez-Figueroa MJ, Blanco-Mendez J: Transdermal delivery of methotrexate: iontophoric delivery from hydrogel and passive delivery from microemulsion. Int J Pharm, 2001; 215: 57-65
6. Hong MS, Lim Sj, Lee MK, Kim CK: Prolonged blood circulation of methotrexate by modulation of liposomal composition. J Drug delivery, 2001; 8: 231-37
7. Westhaus E, Messersmith PB: Triggered release of calcium from lipid vesicles: a bioinspired strategy for rapid gelation of polysaccharide and protein hydrogels. Biomaterials, 2001; 22: 453-62
8. Kosloski MJ, Rosen F, Mlholland RJ, Papahadjopoulos D: Effect of Lipid Vesicles (liposomes) Encapsulation of methorexate on its chemotherapeutic efficacy in solid roden tumors. Can Res, 1978; 38: 2848-53
9. Subramanian N, Arulsudar N, Chuttani K et al: Radiolabeling, Biodistribution and Tumor Imaging of Stealth Liposomes Containing Methotrexate. Alasbimn Journal (serial online), 2003; 22
10. Drummond DC, Myeyer O, Hong K et al: Optimizing liposomes for delivery of chemotherapeutic agents to solid tumours. Pharmcol Rev, 1999; 5: 691-744
11. Tiwari Sandip B, Udupa N, Rao BSS, Uma Devi P: Thermosensitive liposomes and localized hyperthermia. Indian J pharmacol, 2000; 32: 214-20
12. Trotta M, Peir E, Carlotti ME, Gallarate M: Deformable liposomes for dermal administration of methotrexate. Int J Pharm, 2004; 270: 119-25
13. Lasic DD: Lpiosomes: From Physics to Applications. Part III Application of liposomes in Pharmacology and Medicin, Elsevier Science Pub BV, Amesterdam, 1993; 320
14. Bisby RH, Mead C, Morgan CG: Wavelength- programmed solute release from photosensitive liposomes. Biochem Biophys Res Commun, 2000; 276(1): 169-73
15. Stevenson RW, Patel HM, Parsons JA, Ryman B: Prolonged hypoglycemic effect in diabetic dogs due to subcutaneous administration of insulin liposomes. Diabetes, 1982; 31: 506-11
16. Ali MFM: Study effect of laser on the chemical stability and release kinetics of methotrexate loaded in low cost liposomes. Egypt J Biomed Sci, 2005; 17: 254-67
17. Ali MFM: Laser targeting to topically applied gel containing low cost liposomes loaded with methotrexate. In vitro and In vivo study. Bull Fac Pharm Cairo Univ, 2005; 43: 61-67
18. Bangham AD, Standish MM, Watkins JC: Diffusion of univalent ions across lamellae of swollen phospholipids. J Mol Biol, 1965; 13: 238-52
19. Bruce M, Victoria M, Vanderkem R et al (eds.): Laser in Plastic Surgery and Dermatology, Thiem Med Publishers Inc, NewYork, 1992; 1-30
20. Shade VP, Tymes NW, Yamamoto LA, Skelly JP: In vitro dissolution profile of transdermal nitroglycerin patches using paddle method, Int J Pharm, 1986; 32: 243-50
21. Tardiff RG, Hubner RP, Graves CG: Harmonization of thresholds for primary skin irritation from results of human repeated insult patch tests and laboratory animal skin irritation tests. J Appl Toxicol, 2003; 23: 279-81
22. Cammarata F, Wautell T: Medical lasers and laser-tissue interactions. Phys Education, 1999; 34: 156-61
23. Ghannam MM, Al-Talhan MS, Al-Ayed MS, Azeer AM: Study of the physical properties of laser exposed liposomes. Egypt J Biophysics, 2003; 9: 9-29
24. Callen JP, Kulpshorten CL: Methotrexate. In: Stephen E, Wolverton and Jonathan K Wilkin (eds). Systemic drugs for skin diseases. W.B Saunder Company Harcourt Brace Jovanovich Inc, 1991; 152-66
25. Jing Z: Shanghai International Conference on Laser Medicine and Surgery, 2005; Proceedings of the SPIE, 2004; 5967: 286-90