-
1
-
-
45149125881
-
Design opportunities for actively targeted nanoparticle vaccines
-
Fahmy T.M., et al. Design opportunities for actively targeted nanoparticle vaccines. Nanomedicine (Lond.) 2008, 3:343-355.
-
(2008)
Nanomedicine (Lond.)
, vol.3
, pp. 343-355
-
-
Fahmy, T.M.1
-
2
-
-
2342487329
-
Advances in vaccine adjuvants for infectious diseases
-
Singh M., Srivastava I. Advances in vaccine adjuvants for infectious diseases. Curr. HIV Res. 2003, 1:309-320.
-
(2003)
Curr. HIV Res.
, vol.1
, pp. 309-320
-
-
Singh, M.1
Srivastava, I.2
-
3
-
-
2942620283
-
European union regulatory developments for new vaccine adjuvants and delivery systems
-
Sesardic D., Dobbelaer R. European union regulatory developments for new vaccine adjuvants and delivery systems. Vaccine 2004, 22:2452-2456.
-
(2004)
Vaccine
, vol.22
, pp. 2452-2456
-
-
Sesardic, D.1
Dobbelaer, R.2
-
5
-
-
17644416719
-
Targeting the innate immune response with improved vaccine adjuvants
-
Pashine A., et al. Targeting the innate immune response with improved vaccine adjuvants. Nat. Med. 2005, 11:S63-S68.
-
(2005)
Nat. Med.
, vol.11
-
-
Pashine, A.1
-
6
-
-
4243187214
-
Aluminium adjuvants - in retrospect and prospect
-
Lindblad E.B. Aluminium adjuvants - in retrospect and prospect. Vaccine 2004, 22:3658-3668.
-
(2004)
Vaccine
, vol.22
, pp. 3658-3668
-
-
Lindblad, E.B.1
-
7
-
-
0027522991
-
Adjuvants - a balance between toxicity and adjuvanticity
-
Gupta R.K., et al. Adjuvants - a balance between toxicity and adjuvanticity. Vaccine 1993, 11:293-306.
-
(1993)
Vaccine
, vol.11
, pp. 293-306
-
-
Gupta, R.K.1
-
8
-
-
0028884598
-
Adjuvants for human vaccines - current status, problems and future prospects
-
Gupta R.K., Siber G.R. Adjuvants for human vaccines - current status, problems and future prospects. Vaccine 1995, 13:1263-1276.
-
(1995)
Vaccine
, vol.13
, pp. 1263-1276
-
-
Gupta, R.K.1
Siber, G.R.2
-
9
-
-
71849103233
-
Financing the delivery of vaccines to children and adolescents: challenges to the current system
-
Lindley M.C., et al. Financing the delivery of vaccines to children and adolescents: challenges to the current system. Pediatrics 2009, 124(Suppl. 5):S548-S557.
-
(2009)
Pediatrics
, vol.124
, Issue.SUPPL. 5
-
-
Lindley, M.C.1
-
10
-
-
67349117322
-
Current challenges in implementing cell-derived influenza vaccines: implications for production and regulation, July 2007, NIBSC, Potters Bar, UK
-
Minor P.D., et al. Current challenges in implementing cell-derived influenza vaccines: implications for production and regulation, July 2007, NIBSC, Potters Bar, UK. Vaccine 2009, 27:2907-2913.
-
(2009)
Vaccine
, vol.27
, pp. 2907-2913
-
-
Minor, P.D.1
-
11
-
-
33745987658
-
Rotavirus vaccines: current prospects and future challenges
-
Glass R.I., et al. Rotavirus vaccines: current prospects and future challenges. Lancet 2006, 368:323-332.
-
(2006)
Lancet
, vol.368
, pp. 323-332
-
-
Glass, R.I.1
-
12
-
-
33646439910
-
Current advances and challenges in HIV-1 vaccines
-
Rodriguez-Chavez I.R., et al. Current advances and challenges in HIV-1 vaccines. Curr. HIV/AIDS Rep. 2006, 3:39-47.
-
(2006)
Curr. HIV/AIDS Rep.
, vol.3
, pp. 39-47
-
-
Rodriguez-Chavez, I.R.1
-
13
-
-
20344369807
-
Antigen processing and presentation by dendritic cells: cell biological mechanisms
-
Mellman I. Antigen processing and presentation by dendritic cells: cell biological mechanisms. Adv. Exp. Med. Biol. 2005, 560:63-67.
-
(2005)
Adv. Exp. Med. Biol.
, vol.560
, pp. 63-67
-
-
Mellman, I.1
-
14
-
-
0035838984
-
Dendritic cells: specialized and regulated antigen processing machines
-
Mellman I., Steinman R.M. Dendritic cells: specialized and regulated antigen processing machines. Cell 2001, 106:255-258.
-
(2001)
Cell
, vol.106
, pp. 255-258
-
-
Mellman, I.1
Steinman, R.M.2
-
15
-
-
34848837386
-
Taking dendritic cells into medicine
-
Steinman R.M., Banchereau J. Taking dendritic cells into medicine. Nature 2007, 449:419-426.
-
(2007)
Nature
, vol.449
, pp. 419-426
-
-
Steinman, R.M.1
Banchereau, J.2
-
16
-
-
33750934617
-
Dendritic cells: translating innate to adaptive immunity
-
Steinman R.M., Hemmi H. Dendritic cells: translating innate to adaptive immunity. Curr. Top Microbiol. Immunol. 2006, 311:17-58.
-
(2006)
Curr. Top Microbiol. Immunol.
, vol.311
, pp. 17-58
-
-
Steinman, R.M.1
Hemmi, H.2
-
17
-
-
79956114010
-
Pathogen-associated molecular patterns on biomaterials: a paradigm for engineering new vaccines
-
Demento S.L., et al. Pathogen-associated molecular patterns on biomaterials: a paradigm for engineering new vaccines. Trends Biotechnol. 2011, 29:294-306.
-
(2011)
Trends Biotechnol.
, vol.29
, pp. 294-306
-
-
Demento, S.L.1
-
18
-
-
0037375713
-
The use of dendritic cells in cancer immunotherapy
-
Schuler G., et al. The use of dendritic cells in cancer immunotherapy. Curr. Opin. Immunol. 2003, 15:138-147.
-
(2003)
Curr. Opin. Immunol.
, vol.15
, pp. 138-147
-
-
Schuler, G.1
-
19
-
-
34547152610
-
Tolerogenic dendritic cells and the quest for transplant tolerance
-
Morelli A., Thomson A. Tolerogenic dendritic cells and the quest for transplant tolerance. Nat. Rev. Immunol. 2007, 7:610-621.
-
(2007)
Nat. Rev. Immunol.
, vol.7
, pp. 610-621
-
-
Morelli, A.1
Thomson, A.2
-
20
-
-
0037080938
-
Manipulation of dendritic cells for tolerance induction in transplantation and autoimmune disease
-
Lu L., Thomson A.W. Manipulation of dendritic cells for tolerance induction in transplantation and autoimmune disease. Transplantation 2002, 73(Suppl. 1):S19-S22.
-
(2002)
Transplantation
, vol.73
, Issue.SUPPL. 1
-
-
Lu, L.1
Thomson, A.W.2
-
21
-
-
13144256708
-
Rapamycin-treated, alloantigen-pulsed host dendritic cells induce Ag-specific T cell regulation and prolong graft survival
-
Taner T., et al. Rapamycin-treated, alloantigen-pulsed host dendritic cells induce Ag-specific T cell regulation and prolong graft survival. Am. J. Transplant. 2005, 5:228-236.
-
(2005)
Am. J. Transplant.
, vol.5
, pp. 228-236
-
-
Taner, T.1
-
22
-
-
34249805413
-
Rapamycin-conditioned dendritic cells are poor stimulators of allogeneic CD4+ T cells, but enrich for antigen-specific Foxp3+ T regulatory cells and promote organ transplant tolerance
-
Turnquist H.R., et al. Rapamycin-conditioned dendritic cells are poor stimulators of allogeneic CD4+ T cells, but enrich for antigen-specific Foxp3+ T regulatory cells and promote organ transplant tolerance. J. Immunol. 2007, 178:7018-7031.
-
(2007)
J. Immunol.
, vol.178
, pp. 7018-7031
-
-
Turnquist, H.R.1
-
23
-
-
79952320231
-
The evolving role of mTOR inhibition in transplantation tolerance
-
McMahon G., et al. The evolving role of mTOR inhibition in transplantation tolerance. J. Am. Soc. Nephrol. 2011, 22:408-415.
-
(2011)
J. Am. Soc. Nephrol.
, vol.22
, pp. 408-415
-
-
McMahon, G.1
-
24
-
-
39749116753
-
Delivery of rapamycin by PLGA nanoparticles enhances its suppressive activity on dendritic cells
-
Haddadi A., et al. Delivery of rapamycin by PLGA nanoparticles enhances its suppressive activity on dendritic cells. J. Biomed. Mater. Res. A. 2008, 84A:885-898.
-
(2008)
J. Biomed. Mater. Res. A.
, vol.84 A
, pp. 885-898
-
-
Haddadi, A.1
-
25
-
-
82455164104
-
Nanoparticle delivery of mycophenolic acid upregulates PD-L1 on dendritic cells to prolong murine allograft survival
-
Look M., et al. Nanoparticle delivery of mycophenolic acid upregulates PD-L1 on dendritic cells to prolong murine allograft survival. Am. J. Transplant. 2011, 10.1111/j.1600-6143.2011.03725.x.
-
(2011)
Am. J. Transplant.
-
-
Look, M.1
-
26
-
-
67349114782
-
FOXP3 and the regulation of Treg/Th17 differentiation
-
Ziegler S.F., Buckner J.H. FOXP3 and the regulation of Treg/Th17 differentiation. Microbes Infect. 2009, 11:594-598.
-
(2009)
Microbes Infect.
, vol.11
, pp. 594-598
-
-
Ziegler, S.F.1
Buckner, J.H.2
-
27
-
-
77950349016
-
Th17 and regulatory T cells in mediating and restraining inflammation
-
Littman D.R., Rudensky A.Y. Th17 and regulatory T cells in mediating and restraining inflammation. Cell 2010, 140:845-858.
-
(2010)
Cell
, vol.140
, pp. 845-858
-
-
Littman, D.R.1
Rudensky, A.Y.2
-
28
-
-
3242787209
-
Role for CD4(+) CD25(+) regulatory T cells in reactivation of persistent leishmaniasis and control of concomitant immunity
-
Mendez S., et al. Role for CD4(+) CD25(+) regulatory T cells in reactivation of persistent leishmaniasis and control of concomitant immunity. J. Exp. Med. 2004, 200:201-210.
-
(2004)
J. Exp. Med.
, vol.200
, pp. 201-210
-
-
Mendez, S.1
-
29
-
-
30144442053
-
Immunotherapy: suppressing regulatory T cells
-
McCarthy N. Immunotherapy: suppressing regulatory T cells. Nat. Rev. Cancer 2006, 6:6.
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 6
-
-
McCarthy, N.1
-
30
-
-
16244415192
-
Leukemia inhibitory factor is linked to regulatory transplantation tolerance
-
Metcalfe S.M., et al. Leukemia inhibitory factor is linked to regulatory transplantation tolerance. Transplantation 2005, 79:726-730.
-
(2005)
Transplantation
, vol.79
, pp. 726-730
-
-
Metcalfe, S.M.1
-
31
-
-
67650032868
-
A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells
-
Niwa H., et al. A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells. Nature 2009, 460:118-122.
-
(2009)
Nature
, vol.460
, pp. 118-122
-
-
Niwa, H.1
-
32
-
-
65949124869
-
Treg versus Th17 lymphocyte lineages are cross-regulated by LIF versus IL-6
-
Gao W., et al. Treg versus Th17 lymphocyte lineages are cross-regulated by LIF versus IL-6. Cell Cycle 2009, 8:1444-1450.
-
(2009)
Cell Cycle
, vol.8
, pp. 1444-1450
-
-
Gao, W.1
-
33
-
-
10344231444
-
Transplantation tolerance: gene expression profiles comparing allotolerance vs. allorejection
-
Metcalfe, S.M. and De S Muthukumarana, P.A. (2005) Transplantation tolerance: gene expression profiles comparing allotolerance vs. allorejection. Int. Immunopharmacol. 5, 33-39.
-
(2005)
Int. Immunopharmacol.
, vol.5
, pp. 33-39
-
-
Metcalfe, S.M.1
De S Muthukumarana, P.A.2
-
34
-
-
12744262051
-
Leukaemia inhibitory factor (LIF) is functionally linked to axotrophin and both LIF and axotrophin are linked to regulatory immune tolerance
-
Metcalfe S.M., et al. Leukaemia inhibitory factor (LIF) is functionally linked to axotrophin and both LIF and axotrophin are linked to regulatory immune tolerance. FEBS Lett. 2005, 579:609-614.
-
(2005)
FEBS Lett.
, vol.579
, pp. 609-614
-
-
Metcalfe, S.M.1
-
35
-
-
46249111235
-
Functional immobilization of signaling proteins enables control of stem cell fate
-
Alberti K., et al. Functional immobilization of signaling proteins enables control of stem cell fate. Nat. Methods 2008, 5:645-650.
-
(2008)
Nat. Methods
, vol.5
, pp. 645-650
-
-
Alberti, K.1
-
36
-
-
79952934026
-
Modulation of CD4+ T lymphocyte lineage outcomes with targeted, nanoparticle-mediated cytokine delivery
-
Park J., et al. Modulation of CD4+ T lymphocyte lineage outcomes with targeted, nanoparticle-mediated cytokine delivery. Mol. Pharm. 2011, 8:143-152.
-
(2011)
Mol. Pharm.
, vol.8
, pp. 143-152
-
-
Park, J.1
-
37
-
-
79952915024
-
Sub-optimal CD4+ T-cell activation triggers autonomous TGF-beta-dependent conversion to Foxp3+ regulatory T cells
-
Oliveira V.G., et al. Sub-optimal CD4+ T-cell activation triggers autonomous TGF-beta-dependent conversion to Foxp3+ regulatory T cells. Eur. J. Immunol. 2011, 41:1249-1255.
-
(2011)
Eur. J. Immunol.
, vol.41
, pp. 1249-1255
-
-
Oliveira, V.G.1
-
38
-
-
79960369458
-
HIF1{alpha}-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells
-
Shi L.Z., et al. HIF1{alpha}-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells. J. Exp. Med. 2011, 208:1367-1376.
-
(2011)
J. Exp. Med.
, vol.208
, pp. 1367-1376
-
-
Shi, L.Z.1
-
39
-
-
79551594322
-
An epigenetic Tet a Tet with pluripotency
-
Walter J. An epigenetic Tet a Tet with pluripotency. Cell Stem Cell 2011, 8:121-122.
-
(2011)
Cell Stem Cell
, vol.8
, pp. 121-122
-
-
Walter, J.1
-
40
-
-
0037350661
-
TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10;11)(q22;q23)
-
Lorsbach R.B., et al. TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10;11)(q22;q23). Leukemia 2003, 17:637-641.
-
(2003)
Leukemia
, vol.17
, pp. 637-641
-
-
Lorsbach, R.B.1
-
41
-
-
0037068752
-
FR901228, an inhibitor of histone deacetylases, increases the cellular responsiveness to IL-6 type cytokines by enhancing the expression of receptor proteins
-
Blanchard F., et al. FR901228, an inhibitor of histone deacetylases, increases the cellular responsiveness to IL-6 type cytokines by enhancing the expression of receptor proteins. Oncogene 2002, 21:6264-6277.
-
(2002)
Oncogene
, vol.21
, pp. 6264-6277
-
-
Blanchard, F.1
-
42
-
-
33750499991
-
A role for Dicer in immune regulation
-
Cobb B.S., et al. A role for Dicer in immune regulation. J. Exp. Med. 2006, 203:2519-2527.
-
(2006)
J. Exp. Med.
, vol.203
, pp. 2519-2527
-
-
Cobb, B.S.1
-
43
-
-
34247555353
-
Differentiation and function of Th17 T cells
-
Stockinger B., Veldhoen M. Differentiation and function of Th17 T cells. Curr. Opin. Immunol. 2007, 19:281-286.
-
(2007)
Curr. Opin. Immunol.
, vol.19
, pp. 281-286
-
-
Stockinger, B.1
Veldhoen, M.2
-
44
-
-
68249160054
-
Blockade of interleukin-6 signaling augments regulatory T-cell reconstitution and attenuates the severity of graft-versus-host disease
-
Chen X., et al. Blockade of interleukin-6 signaling augments regulatory T-cell reconstitution and attenuates the severity of graft-versus-host disease. Blood 2009, 114:891-900.
-
(2009)
Blood
, vol.114
, pp. 891-900
-
-
Chen, X.1
-
45
-
-
77957054466
-
The mammalian target of rapamycin: linking T cell differentiation, function, and metabolism
-
Powell J.D., Delgoffe G.M. The mammalian target of rapamycin: linking T cell differentiation, function, and metabolism. Immunity 2010, 33:301-311.
-
(2010)
Immunity
, vol.33
, pp. 301-311
-
-
Powell, J.D.1
Delgoffe, G.M.2
-
46
-
-
33644828066
-
Axotrophin and leukaemia inhibitory factor (LIF) in transplantation tolerance
-
Metcalfe S.M. Axotrophin and leukaemia inhibitory factor (LIF) in transplantation tolerance. Philos. Trans. R. Soc. Lond. B. Biol. Sci. 2005, 360:1687-1694.
-
(2005)
Philos. Trans. R. Soc. Lond. B. Biol. Sci.
, vol.360
, pp. 1687-1694
-
-
Metcalfe, S.M.1
-
47
-
-
77958486275
-
A LIF/Nanog axis is revealed in T lymphocytes that lack MARCH-7, a RINGv E3 ligase that regulates the LIF-receptor
-
Thompson L.H., et al. A LIF/Nanog axis is revealed in T lymphocytes that lack MARCH-7, a RINGv E3 ligase that regulates the LIF-receptor. Cell Cycle 2010, 9:4213-4221.
-
(2010)
Cell Cycle
, vol.9
, pp. 4213-4221
-
-
Thompson, L.H.1
-
48
-
-
33646577466
-
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
-
Bettelli E., et al. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 2006, 441:235-238.
-
(2006)
Nature
, vol.441
, pp. 235-238
-
-
Bettelli, E.1
-
49
-
-
34250330368
-
Hypoxia-inducible factor-1 alpha inhibits self-renewal of mouse embryonic stem cells in vitro via negative regulation of the leukemia inhibitory factor-STAT3 pathway
-
Jeong C.H., et al. Hypoxia-inducible factor-1 alpha inhibits self-renewal of mouse embryonic stem cells in vitro via negative regulation of the leukemia inhibitory factor-STAT3 pathway. J. Biol. Chem. 2007, 282:13672-13679.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 13672-13679
-
-
Jeong, C.H.1
-
50
-
-
73649140983
-
Quantitative phosphoproteomic analysis of the STAT3/IL-6/HIF1alpha signaling network: an initial study in GSC11 glioblastoma stem cells
-
Nilsson C.L., et al. Quantitative phosphoproteomic analysis of the STAT3/IL-6/HIF1alpha signaling network: an initial study in GSC11 glioblastoma stem cells. J. Proteome Res. 2010, 9:430-443.
-
(2010)
J. Proteome Res.
, vol.9
, pp. 430-443
-
-
Nilsson, C.L.1
-
51
-
-
78651462023
-
Modeling the cumulative genetic risk for multiple sclerosis from genome-wide association data
-
Wang J.H., et al. Modeling the cumulative genetic risk for multiple sclerosis from genome-wide association data. Genome Med. 2011, 3:3.
-
(2011)
Genome Med.
, vol.3
, pp. 3
-
-
Wang, J.H.1
-
52
-
-
33847111695
-
The neuropoietic cytokine family in development, plasticity, disease and injury
-
Bauer S., et al. The neuropoietic cytokine family in development, plasticity, disease and injury. Nat. Rev. Neurosci. 2007, 8:221-232.
-
(2007)
Nat. Rev. Neurosci.
, vol.8
, pp. 221-232
-
-
Bauer, S.1
-
53
-
-
78049299952
-
Therapeutic potential of LIF in multiple sclerosis
-
Slaets H., et al. Therapeutic potential of LIF in multiple sclerosis. Trends Mol. Med. 2010, 16:493-500.
-
(2010)
Trends Mol. Med.
, vol.16
, pp. 493-500
-
-
Slaets, H.1
-
54
-
-
79955479260
-
LIF in the regulation of T-cell fate and as a potential therapeutic
-
Metcalfe S.M. LIF in the regulation of T-cell fate and as a potential therapeutic. Genes Immun. 2011, 12:157-168.
-
(2011)
Genes Immun.
, vol.12
, pp. 157-168
-
-
Metcalfe, S.M.1
-
55
-
-
80051869587
-
Leukemia inhibitory factor inhibits T helper 17 cell differentiation and confers treatment effects of neural progenitor cell therapy in autoimmune disease
-
Cao W., et al. Leukemia inhibitory factor inhibits T helper 17 cell differentiation and confers treatment effects of neural progenitor cell therapy in autoimmune disease. Immunity 2011, 35:273-284.
-
(2011)
Immunity
, vol.35
, pp. 273-284
-
-
Cao, W.1
-
56
-
-
80052846766
-
Multiple sclerosis: one protein, two healing properties
-
Metcalfe S.M. Multiple sclerosis: one protein, two healing properties. Nature 2011, 477:287-288.
-
(2011)
Nature
, vol.477
, pp. 287-288
-
-
Metcalfe, S.M.1
-
57
-
-
77957044257
-
Improvement in disability after alemtuzumab treatment of multiple sclerosis is associated with neuroprotective autoimmunity
-
Jones J.L., et al. Improvement in disability after alemtuzumab treatment of multiple sclerosis is associated with neuroprotective autoimmunity. Brain 2010, 133:2232-2247.
-
(2010)
Brain
, vol.133
, pp. 2232-2247
-
-
Jones, J.L.1
-
58
-
-
34447568535
-
Regulatory transplantation tolerance and " stemness" : evidence that Foxp3 may play a regulatory role in SOCS-3 gene transcription
-
Muthukumarana P., et al. Regulatory transplantation tolerance and " stemness" : evidence that Foxp3 may play a regulatory role in SOCS-3 gene transcription. Transplantation 2007, 84(Suppl. 1):S6-S11.
-
(2007)
Transplantation
, vol.84
, Issue.SUPPL. 1
-
-
Muthukumarana, P.1
|