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Volumn 7, Issue 1, 2017, Pages

Transcriptome-based network analysis reveals renal cell type-specific dysregulation of hypoxia-associated transcripts

Author keywords

[No Author keywords available]

Indexed keywords

BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; TRANSCRIPTOME;

EID: 85027878248     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/s41598-017-08492-y     Document Type: Article
Times cited : (58)

References (65)
  • 1
    • 65249160167 scopus 로고    scopus 로고
    • Systematic review of the evidence underlying the association between mineral metabolism disturbances and risk of all-cause mortality, cardiovascular mortality and cardiovascular events in chronic kidney disease
    • Covic, A. et al. Systematic review of the evidence underlying the association between mineral metabolism disturbances and risk of all-cause mortality, cardiovascular mortality and cardiovascular events in chronic kidney disease. Nephrol Dial Transplant 24, 1506-1523, doi:10.1093/ndt/gfn613 (2009).
    • (2009) Nephrol Dial Transplant , vol.24 , pp. 1506-1523
    • Covic, A.1
  • 3
    • 84855854046 scopus 로고    scopus 로고
    • Chronic kidney disease
    • Levey, A. S. & Coresh, J. Chronic kidney disease. Lancet 379, 165-180, doi:10.1016/S0140-6736(11)60178-5 (2012).
    • (2012) Lancet , vol.379 , pp. 165-180
    • Levey, A.S.1    Coresh, J.2
  • 4
    • 77952743230 scopus 로고    scopus 로고
    • Spread of glomerular to tubulointerstitial disease with a focus on proteinuria
    • Theilig, F. Spread of glomerular to tubulointerstitial disease with a focus on proteinuria. Ann Anat 192, 125-132, doi:10.1016/j. aanat.2010.03.003 (2010).
    • (2010) Ann Anat , vol.192 , pp. 125-132
    • Theilig, F.1
  • 5
    • 0032731318 scopus 로고    scopus 로고
    • The tubulointerstitium in progressive diabetic kidney disease: More than an aftermath of glomerular injury?
    • Gilbert, R. E. & Cooper, M. E. The tubulointerstitium in progressive diabetic kidney disease: more than an aftermath of glomerular injury? Kidney international 56, 1627-1637, doi:10.1046/j.1523-1755.1999.00721.x (1999).
    • (1999) Kidney International , vol.56 , pp. 1627-1637
    • Gilbert, R.E.1    Cooper, M.E.2
  • 6
    • 51849094304 scopus 로고    scopus 로고
    • Chronic hypoxia as a mechanism of progression of chronic kidney diseases: From hypothesis to novel therapeutics
    • Fine, L. G. & Norman, J. T. Chronic hypoxia as a mechanism of progression of chronic kidney diseases: from hypothesis to novel therapeutics. Kidney international 74, 867-872, doi:10.1038/ki.2008.350 (2008).
    • (2008) Kidney International , vol.74 , pp. 867-872
    • Fine, L.G.1    Norman, J.T.2
  • 7
    • 78649364332 scopus 로고    scopus 로고
    • Hypoxia-inducible factors and the response to hypoxic stress
    • Majmundar, A. J., Wong, W. J. & Simon, M. C. Hypoxia-inducible factors and the response to hypoxic stress. Molecular cell 40, 294-309, doi:10.1016/j.molcel.2010.09.022 (2010).
    • (2010) Molecular Cell , vol.40 , pp. 294-309
    • Majmundar, A.J.1    Wong, W.J.2    Simon, M.C.3
  • 8
    • 18444380862 scopus 로고    scopus 로고
    • Expression of hypoxia-inducible factor-1alpha and -2alpha in hypoxic and ischemic rat kidneys
    • Rosenberger, C. et al. Expression of hypoxia-inducible factor-1alpha and -2alpha in hypoxic and ischemic rat kidneys. Journal of the American Society of Nephrology: JASN 13, 1721-1732 (2002).
    • (2002) Journal of the American Society of Nephrology: JASN , vol.13 , pp. 1721-1732
    • Rosenberger, C.1
  • 10
    • 0031949073 scopus 로고    scopus 로고
    • Progressive renal disease: The chronic hypoxia hypothesis
    • Fine, L. G., Orphanides, C. & Norman, J. T. Progressive renal disease: the chronic hypoxia hypothesis. Kidney Int Suppl 65, S74-78 (1998).
    • (1998) Kidney Int Suppl , vol.65 , pp. S74-S78
    • Fine, L.G.1    Orphanides, C.2    Norman, J.T.3
  • 11
    • 10744229444 scopus 로고    scopus 로고
    • Transdifferentiation of cultured tubular cells induced by hypoxia
    • Manotham, K. et al. Transdifferentiation of cultured tubular cells induced by hypoxia. Kidney international 65, 871-880, doi:10.1111/j.1523-1755.2004.00461.x (2004).
    • (2004) Kidney International , vol.65 , pp. 871-880
    • Manotham, K.1
  • 12
    • 0042235096 scopus 로고    scopus 로고
    • Hypoxia induces apoptosis in SV40-immortalized rat proximal tubular cells through the mitochondrial pathways, devoid of HIF1-mediated upregulation of bax
    • Tanaka, T. et al. Hypoxia induces apoptosis in SV40-immortalized rat proximal tubular cells through the mitochondrial pathways, devoid of HIF1-mediated upregulation of Bax. Biochemical and biophysical research communications 309, 222-231 (2003).
    • (2003) Biochemical and Biophysical Research Communications , vol.309 , pp. 222-231
    • Tanaka, T.1
  • 13
    • 36849021771 scopus 로고    scopus 로고
    • Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition
    • Higgins, D. F. et al. Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition. The Journal of clinical investigation 117, 3810-3820, doi:10.1172/JCI30487 (2007).
    • (2007) The Journal of Clinical Investigation , vol.117 , pp. 3810-3820
    • Higgins, D.F.1
  • 14
    • 34247864018 scopus 로고    scopus 로고
    • Involvement of hypoxia-inducible transcription factors in polycystic kidney disease
    • Bernhardt, W. M. et al. Involvement of hypoxia-inducible transcription factors in polycystic kidney disease. The American journal of pathology 170, 830-842, doi:10.2353/ajpath.2007.060455 (2007).
    • (2007) The American Journal of Pathology , vol.170 , pp. 830-842
    • Bernhardt, W.M.1
  • 15
    • 34249901258 scopus 로고    scopus 로고
    • Interstitial vascular rarefaction and reduced VEGF-A expression in human diabetic nephropathy
    • Lindenmeyer, M. T. et al. Interstitial vascular rarefaction and reduced VEGF-A expression in human diabetic nephropathy. Journal of the American Society of Nephrology: JASN 18, 1765-1776, doi:10.1681/ASN.2006121304 (2007).
    • (2007) Journal of the American Society of Nephrology: JASN , vol.18 , pp. 1765-1776
    • Lindenmeyer, M.T.1
  • 16
    • 76149112291 scopus 로고    scopus 로고
    • Human nephrosclerosis triggers a hypoxia-related glomerulopathy
    • Neusser, M. A. et al. Human nephrosclerosis triggers a hypoxia-related glomerulopathy. The American journal of pathology 176, 594-607, doi:10.2353/ajpath.2010.090268 (2010).
    • (2010) The American Journal of Pathology , vol.176 , pp. 594-607
    • Neusser, M.A.1
  • 18
    • 84939568249 scopus 로고    scopus 로고
    • Evaluation of renal blood flow and oxygenation in CKD using magnetic resonance imaging
    • Khatir, D. S., Pedersen, M., Jespersen, B. & Buus, N. H. Evaluation of Renal Blood Flow and Oxygenation in CKD Using Magnetic Resonance Imaging. Am J Kidney Dis 66, 402-411, doi:10.1053/j.ajkd.2014.11.022 (2015).
    • (2015) Am J Kidney Dis , vol.66 , pp. 402-411
    • Khatir, D.S.1    Pedersen, M.2    Jespersen, B.3    Buus, N.H.4
  • 20
    • 84861339790 scopus 로고    scopus 로고
    • Non-canonical HIF-2alpha function drives autonomous breast cancer cell growth via an AREG-EGFR/ErbB4 autocrine loop
    • Stiehl, D. P. et al. Non-canonical HIF-2alpha function drives autonomous breast cancer cell growth via an AREG-EGFR/ErbB4 autocrine loop. Oncogene 31, 2283-2297, doi:10.1038/onc.2011.417 (2012).
    • (2012) Oncogene , vol.31 , pp. 2283-2297
    • Stiehl, D.P.1
  • 22
    • 84879696354 scopus 로고    scopus 로고
    • PodNet, a protein-protein interaction network of the podocyte
    • Warsow, G. et al. PodNet, a protein-protein interaction network of the podocyte. Kidney international 84, 104-115, doi:10.1038/ki.2013.64 (2013).
    • (2013) Kidney International , vol.84 , pp. 104-115
    • Warsow, G.1
  • 24
    • 33645452371 scopus 로고    scopus 로고
    • Chronic hypoxia and tubulointerstitial injury: A final common pathway to end-stage renal failure
    • Nangaku, M. Chronic hypoxia and tubulointerstitial injury: a final common pathway to end-stage renal failure. Journal of the American Society of Nephrology: JASN 17, 17-25, doi:10.1681/ASN.2005070757 (2006).
    • (2006) Journal of the American Society of Nephrology: JASN , vol.17 , pp. 17-25
    • Nangaku, M.1
  • 25
    • 79960957297 scopus 로고    scopus 로고
    • Noninvasive evaluation of kidney hypoxia and fibrosis using magnetic resonance imaging
    • Inoue, T. et al. Noninvasive evaluation of kidney hypoxia and fibrosis using magnetic resonance imaging. Journal of the American Society of Nephrology: JASN 22, 1429-1434, doi:10.1681/ASN.2010111143 (2011).
    • (2011) Journal of the American Society of Nephrology: JASN , vol.22 , pp. 1429-1434
    • Inoue, T.1
  • 26
    • 84861651942 scopus 로고    scopus 로고
    • Noninvasive evaluation of renal oxygenation in diabetic nephropathy by BOLD-MRI
    • Yin, W. J. et al. Noninvasive evaluation of renal oxygenation in diabetic nephropathy by BOLD-MRI. European journal of radiology 81, 1426-1431, doi:10.1016/j.ejrad.2011.03.045 (2012).
    • (2012) European Journal of Radiology , vol.81 , pp. 1426-1431
    • Yin, W.J.1
  • 27
    • 79952253559 scopus 로고    scopus 로고
    • Blood oxygen level-dependent (BOLD) MRI of diabetic nephropathy: Preliminary experience
    • Wang, Z. J., Kumar, R., Banerjee, S. & Hsu, C. Y. Blood oxygen level-dependent (BOLD) MRI of diabetic nephropathy: preliminary experience. Journal of magnetic resonance imaging: JMRI 33, 655-660, doi:10.1002/jmri.22501 (2011).
    • (2011) Journal of Magnetic Resonance Imaging: JMRI , vol.33 , pp. 655-660
    • Wang, Z.J.1    Kumar, R.2    Banerjee, S.3    Hsu, C.Y.4
  • 28
    • 0036511165 scopus 로고    scopus 로고
    • Effect of diabetes on renal medullary oxygenation during water diuresis
    • Epstein, F. H., Veves, A. & Prasad, P. V. Effect of diabetes on renal medullary oxygenation during water diuresis. Diabetes care 25, 575-578 (2002).
    • (2002) Diabetes Care , vol.25 , pp. 575-578
    • Epstein, F.H.1    Veves, A.2    Prasad, P.V.3
  • 29
    • 84858331247 scopus 로고    scopus 로고
    • Renal BOLD-MRI does not reflect renal function in chronic kidney disease
    • Michaely, H. J. et al. Renal BOLD-MRI does not reflect renal function in chronic kidney disease. Kidney international 81, 684-689, doi:10.1038/ki.2011.455 (2012).
    • (2012) Kidney International , vol.81 , pp. 684-689
    • Michaely, H.J.1
  • 30
    • 84885154459 scopus 로고    scopus 로고
    • Indoxyl sulfate signals for rapid mRNA stabilization of Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 2 (CITED2) and suppresses the expression of hypoxiainducible genes in experimental CKD and uremia
    • Tanaka, T., Yamaguchi, J., Higashijima, Y. & Nangaku, M. Indoxyl sulfate signals for rapid mRNA stabilization of Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 2 (CITED2) and suppresses the expression of hypoxiainducible genes in experimental CKD and uremia. FASEB journal: official publication of the Federation of American Societies for Experimental Biology 27, 4059-4075, doi:10.1096/fj.13-231837 (2013).
    • (2013) FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology , vol.27 , pp. 4059-4075
    • Tanaka, T.1    Yamaguchi, J.2    Higashijima, Y.3    Nangaku, M.4
  • 31
    • 84885188064 scopus 로고    scopus 로고
    • Hypoxia: A master regulator of microRNA biogenesis and activity
    • Nallamshetty, S., Chan, S. Y. & Loscalzo, J. Hypoxia: a master regulator of microRNA biogenesis and activity. Free radical biology & medicine 64, 20-30, doi:10.1016/j.freeradbiomed.2013.05.022 (2013).
    • (2013) Free Radical Biology & Medicine , vol.64 , pp. 20-30
    • Nallamshetty, S.1    Chan, S.Y.2    Loscalzo, J.3
  • 32
    • 84908453071 scopus 로고    scopus 로고
    • MiR-21 in ischemia/reperfusion injury: A double-edged sword?
    • Xu, X. et al. miR-21 in ischemia/reperfusion injury: a double-edged sword? Physiological genomics 46, 789-797, doi:10.1152/physiolgenomics.00020.2014 (2014).
    • (2014) Physiological Genomics , vol.46 , pp. 789-797
    • Xu, X.1
  • 33
    • 0035142809 scopus 로고    scopus 로고
    • Determination of hypoxic region by hypoxia marker in developing mouse embryos in vivo: A possible signal for vessel development
    • Lee, Y. M. et al. Determination of hypoxic region by hypoxia marker in developing mouse embryos in vivo: a possible signal for vessel development. Developmental dynamics: an official publication of the American Association of Anatomists 220, 175-186, doi: 10.1002/1097-0177(20010201)220:2<175::AID-DVDY1101>3.0.CO;2-F (2001).
    • (2001) Developmental Dynamics: An Official Publication of the American Association of Anatomists , vol.220 , pp. 175-186
    • Lee, Y.M.1
  • 34
    • 84951566665 scopus 로고    scopus 로고
    • Hypoxia inhibits nephrogenesis through paracrine vegfa despite the ability to enhance tubulogenesis
    • Schley, G. et al. Hypoxia inhibits nephrogenesis through paracrine Vegfa despite the ability to enhance tubulogenesis. Kidney international. doi:10.1038/ki.2015.214 (2015).
    • (2015) Kidney International
    • Schley, G.1
  • 35
    • 0347131117 scopus 로고    scopus 로고
    • TGF-beta superfamily members modulate growth, branching, shaping, and patterning of the ureteric bud
    • Bush, K. T. et al. TGF-beta superfamily members modulate growth, branching, shaping, and patterning of the ureteric bud. Developmental biology 266, 285-298 (2004).
    • (2004) Developmental Biology , vol.266 , pp. 285-298
    • Bush, K.T.1
  • 36
    • 33748062324 scopus 로고    scopus 로고
    • Renal bone morphogenetic protein-7 protects against diabetic nephropathy
    • Wang, S. et al. Renal bone morphogenetic protein-7 protects against diabetic nephropathy. Journal of the American Society of Nephrology: JASN 17, 2504-2512, doi:10.1681/ASN.2006030278 (2006).
    • (2006) Journal of the American Society of Nephrology: JASN , vol.17 , pp. 2504-2512
    • Wang, S.1
  • 37
    • 47749136233 scopus 로고    scopus 로고
    • Reversal of experimental renal fibrosis by BMP7 provides insights into novel therapeutic strategies for chronic kidney disease
    • Zeisberg, M. & Kalluri, R. Reversal of experimental renal fibrosis by BMP7 provides insights into novel therapeutic strategies for chronic kidney disease. Pediatr Nephrol 23, 1395-1398, doi:10.1007/s00467-008-0818-x (2008).
    • (2008) Pediatr Nephrol , vol.23 , pp. 1395-1398
    • Zeisberg, M.1    Kalluri, R.2
  • 38
    • 84994253012 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1alpha promotes glomerulosclerosis and regulates COL1A2 expression through interactions with smad3
    • Baumann, B., Hayashida, T., Liang, X. & Schnaper, H. W. Hypoxia-inducible factor-1alpha promotes glomerulosclerosis and regulates COL1A2 expression through interactions with Smad3. Kidney international 90, 797-808, doi:10.1016/j.kint.2016.05.026 (2016).
    • (2016) Kidney International , vol.90 , pp. 797-808
    • Baumann, B.1    Hayashida, T.2    Liang, X.3    Schnaper, H.W.4
  • 39
    • 84988428975 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1alpha activates the transforming growth factor-beta/SMAD3 pathway in kidney tubular epithelial cells
    • Kushida, N. et al. Hypoxia-Inducible Factor-1alpha Activates the Transforming Growth Factor-beta/SMAD3 Pathway in Kidney Tubular Epithelial Cells. American journal of nephrology 44, 276-285, doi:10.1159/000449323 (2016).
    • (2016) American Journal of Nephrology , vol.44 , pp. 276-285
    • Kushida, N.1
  • 40
    • 0032929050 scopus 로고    scopus 로고
    • The dysregulated podocyte phenotype: A novel concept in the pathogenesis of collapsing idiopathic focal segmental glomerulosclerosis and HIV-associated nephropathy
    • Barisoni, L., Kriz, W., Mundel, P. & D'Agati, V. The dysregulated podocyte phenotype: a novel concept in the pathogenesis of collapsing idiopathic focal segmental glomerulosclerosis and HIV-associated nephropathy. Journal of the American Society of Nephrology: JASN 10, 51-61 (1999).
    • (1999) Journal of the American Society of Nephrology: JASN , vol.10 , pp. 51-61
    • Barisoni, L.1    Kriz, W.2    Mundel, P.3    D'Agati, V.4
  • 41
    • 84855537673 scopus 로고    scopus 로고
    • Reversible cell-cycle entry in adult kidney podocytes through regulated control of telomerase and wnt signaling
    • Shkreli, M. et al. Reversible cell-cycle entry in adult kidney podocytes through regulated control of telomerase and Wnt signaling. Nature medicine 18, 111-119, doi:10.1038/nm.2550 (2012).
    • (2012) Nature Medicine , vol.18 , pp. 111-119
    • Shkreli, M.1
  • 43
    • 40449112321 scopus 로고    scopus 로고
    • The notch pathway in podocytes plays a role in the development of glomerular disease
    • Niranjan, T. et al. The Notch pathway in podocytes plays a role in the development of glomerular disease. Nature medicine 14, 290-298, doi:10.1038/nm1731 (2008).
    • (2008) Nature Medicine , vol.14 , pp. 290-298
    • Niranjan, T.1
  • 44
    • 84878644138 scopus 로고    scopus 로고
    • Inhibition of notch pathway attenuates the progression of human immunodeficiency virus-associated nephropathy
    • Sharma, M. et al. Inhibition of Notch pathway attenuates the progression of human immunodeficiency virus-associated nephropathy. Am J Physiol Renal Physiol 304, F1127-1136, doi:10.1152/ajprenal.00475.2012 (2013).
    • (2013) Am J Physiol Renal Physiol , vol.304 , pp. F1127-F1136
    • Sharma, M.1
  • 45
    • 33646471404 scopus 로고    scopus 로고
    • Hypoxia-regulated differentiation: Let's step it up a notch
    • Sainson, R. C. & Harris, A. L. Hypoxia-regulated differentiation: let's step it up a Notch. Trends in molecular medicine 12, 141-143, doi:10.1016/j.molmed.2006.02.001 (2006).
    • (2006) Trends in Molecular Medicine , vol.12 , pp. 141-143
    • Sainson, R.C.1    Harris, A.L.2
  • 46
    • 84903551813 scopus 로고    scopus 로고
    • Lipid biology of the podocyte-new perspectives offer new opportunities
    • Fornoni, A., Merscher, S. & Kopp, J. B. Lipid biology of the podocyte-new perspectives offer new opportunities. Nature reviews. Nephrology 10, 379-388, doi:10.1038/nrneph.2014.87 (2014).
    • (2014) Nature Reviews. Nephrology , vol.10 , pp. 379-388
    • Fornoni, A.1    Merscher, S.2    Kopp, J.B.3
  • 47
    • 84907681499 scopus 로고    scopus 로고
    • Metabolism, energetics, and lipid biology in the podocyte-cellular cholesterol-mediated glomerular injury
    • Merscher, S., Pedigo, C. E. & Mendez, A. J. Metabolism, energetics, and lipid biology in the podocyte-cellular cholesterol-mediated glomerular injury. Frontiers in endocrinology 5, 169, doi:10.3389/fendo.2014.00169 (2014).
    • (2014) Frontiers in Endocrinology , vol.5 , pp. 169
    • Merscher, S.1    Pedigo, C.E.2    Mendez, A.J.3
  • 48
    • 0036070015 scopus 로고    scopus 로고
    • VEGF expression in hypoxia and hyperglycemia: Reciprocal effect on branching angiogenesis in epithelial-endothelial co-cultures
    • Kim, B. S., Chen, J., Weinstein, T., Noiri, E. & Goligorsky, M. S. VEGF expression in hypoxia and hyperglycemia: reciprocal effect on branching angiogenesis in epithelial-endothelial co-cultures. Journal of the American Society of Nephrology: JASN 13, 2027-2036 (2002).
    • (2002) Journal of the American Society of Nephrology: JASN , vol.13 , pp. 2027-2036
    • Kim, B.S.1    Chen, J.2    Weinstein, T.3    Noiri, E.4    Goligorsky, M.S.5
  • 49
    • 48649093670 scopus 로고    scopus 로고
    • EGFR signalling as a negative regulator of notch1 gene transcription and function in proliferating keratinocytes and cancer
    • Kolev, V. et al. EGFR signalling as a negative regulator of Notch1 gene transcription and function in proliferating keratinocytes and cancer. Nature cell biology 10, 902-911, doi:10.1038/ncb1750 (2008).
    • (2008) Nature Cell Biology , vol.10 , pp. 902-911
    • Kolev, V.1
  • 50
    • 84866172766 scopus 로고    scopus 로고
    • HIF-1 versus HIF-2-is one more important than the other?
    • Loboda, A., Jozkowicz, A. & Dulak, J. HIF-1 versus HIF-2-is one more important than the other? Vascular pharmacology 56, 245-251, doi:10.1016/j.vph.2012.02.006 (2012).
    • (2012) Vascular Pharmacology , vol.56 , pp. 245-251
    • Loboda, A.1    Jozkowicz, A.2    Dulak, J.3
  • 51
    • 35848938945 scopus 로고    scopus 로고
    • The N-terminal transactivation domain confers target gene specificity of hypoxia-inducible factors HIF-1alpha and HIF-2alpha
    • Hu, C. J., Sataur, A., Wang, L., Chen, H. & Simon, M. C. The N-terminal transactivation domain confers target gene specificity of hypoxia-inducible factors HIF-1alpha and HIF-2alpha. Molecular biology of the cell 18, 4528-4542, doi:10.1091/mbc.E06-05-0419 (2007).
    • (2007) Molecular Biology of the Cell , vol.18 , pp. 4528-4542
    • Hu, C.J.1    Sataur, A.2    Wang, L.3    Chen, H.4    Simon, M.C.5
  • 52
    • 0036147231 scopus 로고    scopus 로고
    • Quantitative gene expression analysis in renal biopsies: A novel protocol for a high-throughput multicenter application
    • Cohen, C. D., Frach, K., Schlondorff, D. & Kretzler, M. Quantitative gene expression analysis in renal biopsies: a novel protocol for a high-throughput multicenter application. Kidney international 61, 133-140, doi:10.1046/j.1523-1755.2002.00113.x (2002).
    • (2002) Kidney International , vol.61 , pp. 133-140
    • Cohen, C.D.1    Frach, K.2    Schlondorff, D.3    Kretzler, M.4
  • 53
    • 84924009565 scopus 로고    scopus 로고
    • Integrative biology identifies shared transcriptional networks in CKD
    • Martini, S. et al. Integrative biology identifies shared transcriptional networks in CKD. Journal of the American Society of Nephrology: JASN 25, 2559-2572, doi:10.1681/ASN.2013080906 (2014).
    • (2014) Journal of the American Society of Nephrology: JASN , vol.25 , pp. 2559-2572
    • Martini, S.1
  • 54
    • 33645807621 scopus 로고    scopus 로고
    • Comparative promoter analysis allows de novo identification of specialized cell junction-associated proteins
    • Cohen, C. D. et al. Comparative promoter analysis allows de novo identification of specialized cell junction-associated proteins. Proceedings of the National Academy of Sciences of the United States of America 103, 5682-5687, doi:10.1073/pnas.0511257103 (2006).
    • (2006) Proceedings of the National Academy of Sciences of the United States of America , vol.103 , pp. 5682-5687
    • Cohen, C.D.1
  • 55
    • 33845432928 scopus 로고    scopus 로고
    • Adjusting batch effects in microarray expression data using empirical bayes methods
    • Johnson, W. E., Li, C. & Rabinovic, A. Adjusting batch effects in microarray expression data using empirical Bayes methods. Biostatistics 8, 118-127, doi:10.1093/biostatistics/kxj037 (2007).
    • (2007) Biostatistics , vol.8 , pp. 118-127
    • Johnson, W.E.1    Li, C.2    Rabinovic, A.3
  • 56
    • 65649142017 scopus 로고    scopus 로고
    • A new equation to estimate glomerular filtration rate
    • Levey, A. S. et al. A new equation to estimate glomerular filtration rate. Ann Intern Med 150, 604-612 (2009).
    • (2009) Ann Intern Med , vol.150 , pp. 604-612
    • Levey, A.S.1
  • 57
    • 33747660292 scopus 로고    scopus 로고
    • Increased prolyl 4-hydroxylase domain proteins compensate for decreased oxygen levels. Evidence for an autoregulatory oxygen-sensing system
    • Stiehl, D. P. et al. Increased prolyl 4-hydroxylase domain proteins compensate for decreased oxygen levels. Evidence for an autoregulatory oxygen-sensing system. The Journal of biological chemistry 281, 23482-23491, doi:10.1074/jbc.M601719200 (2006).
    • (2006) The Journal of Biological Chemistry , vol.281 , pp. 23482-23491
    • Stiehl, D.P.1
  • 59
    • 55749105700 scopus 로고    scopus 로고
    • Proteinuria and hyperglycemia induce endoplasmic reticulum stress
    • Lindenmeyer, M. T. et al. Proteinuria and hyperglycemia induce endoplasmic reticulum stress. Journal of the American Society of Nephrology: JASN 19, 2225-2236, doi:10.1681/ASN.2007121313 (2008).
    • (2008) Journal of the American Society of Nephrology: JASN , vol.19 , pp. 2225-2236
    • Lindenmeyer, M.T.1
  • 60
    • 60549111634 scopus 로고    scopus 로고
    • WGCNA: An R package for weighted correlation network analysis
    • Langfelder, P. & Horvath, S. WGCNA: an R package for weighted correlation network analysis. BMC bioinformatics 9, 559, doi:10.1186/1471-2105-9-559 (2008).
    • (2008) BMC Bioinformatics , vol.9 , pp. 559
    • Langfelder, P.1    Horvath, S.2
  • 61
    • 24044440971 scopus 로고    scopus 로고
    • BiNGO: A cytoscape plugin to assess overrepresentation of gene ontology categories in biological networks
    • Maere, S., Heymans, K. & Kuiper, M. BiNGO: a Cytoscape plugin to assess overrepresentation of gene ontology categories in biological networks. Bioinformatics 21, 3448-3449, doi:10.1093/bioinformatics/bti551 (2005).
    • (2005) Bioinformatics , vol.21 , pp. 3448-3449
    • Maere, S.1    Heymans, K.2    Kuiper, M.3
  • 62
    • 84883147423 scopus 로고    scopus 로고
    • Elucidating functional context within microarray data by integrated transcription factor-focused gene-interaction and regulatory network analysis
    • Werner, T. et al. Elucidating functional context within microarray data by integrated transcription factor-focused gene-interaction and regulatory network analysis. European cytokine network 24, 75-90, doi:10.1684/ecn.2013.0336 (2013).
    • (2013) European Cytokine Network , vol.24 , pp. 75-90
    • Werner, T.1
  • 63
    • 0242490780 scopus 로고    scopus 로고
    • Cytoscape: A software environment for integrated models of biomolecular interaction networks
    • Shannon, P. et al. Cytoscape: a software environment for integrated models of biomolecular interaction networks. Genome research 13, 2498-2504, doi:10.1101/gr.1239303 (2003).
    • (2003) Genome Research , vol.13 , pp. 2498-2504
    • Shannon, P.1


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