Hypoxia inhibits nephrogenesis through paracrine Vegfa despite the ability to enhance tubulogenesis

Kidney International

Volumn 88, Issue 6, 2015, Pages 1283-1292

  Schley, Gunnar ^a   Scholz, Holger ^b   Kraus, Andre ^a   Hackenbeck, Thomas ^a   Klanke, Bernd ^a   Willam, Carsten ^a   Wiesener, Michael S ^a   Heinze, Eva ^a   Burzlaff, Nicolai ^a   Eckardt, Kai Uwe ^a   Buchholz, Bjoern ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Hypoxia; Hypoxia inducible factor 1 ; Kidney development; Metanephric mesenchyme; Nephrogenesis; Vegfa

Indexed keywords

BONE MORPHOGENETIC PROTEIN 4; HYPOXIA INDUCIBLE FACTOR 1ALPHA; VASCULOTROPIN A;

ADULT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRANCHING MORPHOGENESIS; CELL GROWTH; CELL SPECIFICITY; CONTROLLED STUDY; EMBRYO; GENE INACTIVATION; HYPOXIA; KIDNEY CELL CULTURE; KIDNEY DEVELOPMENT; KIDNEY MESENCHYME CELL; MALE; MDCK CELL LINE; MOUSE; NONHUMAN; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN STABILITY; URETER;

EID: 84951566665     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2015.214     Document Type: Article

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