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Volumn 7, Issue 2, 2017, Pages

DNA methylation as a putative mechanism for reduced dendritic spine density in the superior temporal gyrus of subjects with schizophrenia

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN SPECIFIC ANGIOGENESIS INHIBITOR 1 ASSOCIATED PROTEIN 2; LONG UNTRANSLATED RNA; PROTEIN; UNCLASSIFIED DRUG; BAIAP2 PROTEIN, HUMAN; DLG1 PROTEIN, HUMAN; MEMBRANE PROTEIN; NERVE PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

EID: 85027575917     PISSN: None     EISSN: 21583188     Source Type: Journal    
DOI: 10.1038/tp.2016.297     Document Type: Article
Times cited : (27)

References (72)
  • 1
    • 65249107131 scopus 로고    scopus 로고
    • Schizophrenia from a neural circuitry perspective: Advancing toward rational pharmacological therapies
    • Lewis DA, Sweet RA. Schizophrenia from a neural circuitry perspective: advancing toward rational pharmacological therapies. J Clin Invest 2009; 119: 706-716.
    • (2009) J Clin Invest , vol.119 , pp. 706-716
    • Lewis, D.A.1    Sweet, R.A.2
  • 2
    • 84939798927 scopus 로고    scopus 로고
    • Auditory dysfunction in schizophrenia: Integrating clinical and basic features
    • Javitt DC, Sweet RA. Auditory dysfunction in schizophrenia: integrating clinical and basic features. Nat Rev Neurosci 2015; 16: 535-550.
    • (2015) Nat Rev Neurosci , vol.16 , pp. 535-550
    • Javitt, D.C.1    Sweet, R.A.2
  • 3
    • 84884288041 scopus 로고    scopus 로고
    • Dendritic spine pathology in schizophrenia
    • Glausier JR, Lewis DA. Dendritic spine pathology in schizophrenia. Neuroscience 2013; 251: 90-107.
    • (2013) Neuroscience , vol.251 , pp. 90-107
    • Glausier, J.R.1    Lewis, D.A.2
  • 4
    • 84949824308 scopus 로고    scopus 로고
    • Dendritic spine alterations in schizophrenia
    • Moyer CE, Shelton MA, Sweet RA. Dendritic spine alterations in schizophrenia. Neurosci Lett 2015; 601: 46-53.
    • (2015) Neurosci Lett , vol.601 , pp. 46-53
    • Moyer, C.E.1    Shelton, M.A.2    Sweet, R.A.3
  • 5
    • 84939555858 scopus 로고    scopus 로고
    • Loss of microtubule-associated protein 2 immunoreactivity linked to dendritic spine loss in schizophrenia
    • Shelton MA, Newman JT, Gu H, Sampson AR, Fish KN, MacDonald ML et al. Loss of microtubule-associated protein 2 immunoreactivity linked to dendritic spine loss in schizophrenia. Biol Psychiatry 2015; 78: 374-385.
    • (2015) Biol Psychiatry , vol.78 , pp. 374-385
    • Shelton, M.A.1    Newman, J.T.2    Gu, H.3    Sampson, A.R.4    Fish, K.N.5    MacDonald, M.L.6
  • 7
    • 21844450880 scopus 로고    scopus 로고
    • Intermediate phenotypes in schizophrenia: A selective review
    • Preston GA, Weinberger DR. Intermediate phenotypes in schizophrenia: a selective review. Dialogues Clin Neurosci 2005; 7: 165-179.
    • (2005) Dialogues Clin Neurosci , vol.7 , pp. 165-179
    • Preston, G.A.1    Weinberger, D.R.2
  • 9
    • 84861198820 scopus 로고    scopus 로고
    • Neuronal D-serine regulates dendritic architecture in the somatosensory cortex
    • Balu DT, Coyle JT. Neuronal D-serine regulates dendritic architecture in the somatosensory cortex. Neurosci Lett 2012; 517: 77-81.
    • (2012) Neurosci Lett , vol.517 , pp. 77-81
    • Balu, D.T.1    Coyle, J.T.2
  • 10
    • 84879518895 scopus 로고    scopus 로고
    • Multiple risk pathways for schizophrenia converge in serine racemase knockout mice, a mouse model of NMDA receptor hypofunction
    • Balu DT, Li Y, Puhl MD, Benneyworth MA, Basu AC, Takagi S et al. Multiple risk pathways for schizophrenia converge in serine racemase knockout mice, a mouse model of NMDA receptor hypofunction. Proc Natl Acad Sci U S A 2013; 110: E2400-E2409.
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. E2400-E2409
    • Balu, D.T.1    Li, Y.2    Puhl, M.D.3    Benneyworth, M.A.4    Basu, A.C.5    Takagi, S.6
  • 11
    • 84904815902 scopus 로고    scopus 로고
    • Schizophrenia Working Group of the Psychiatric Genomics C. Schizophreniaassociated genetic loci
    • Schizophrenia Working Group of the Psychiatric Genomics C. schizophreniaassociated genetic loci. Nature 2014; 511: 421-427.
    • (2014) Nature , vol.511 , pp. 421-427
  • 13
    • 84898412528 scopus 로고    scopus 로고
    • Abnormal kalirin signaling in neuropsychiatric disorders
    • Remmers C, Sweet RA, Penzes P. Abnormal kalirin signaling in neuropsychiatric disorders. Brain Res Bull 2014; 103: 29-38.
    • (2014) Brain Res Bull , vol.103 , pp. 29-38
    • Remmers, C.1    Sweet, R.A.2    Penzes, P.3
  • 14
    • 84860130779 scopus 로고    scopus 로고
    • Resequencing and association analysis of the KALRN and EPHB1 genes and their contribution to schizophrenia susceptibility
    • Kushima I, Nakamura Y, Aleksic B, Ikeda M, Ito Y, Shiino T et al. Resequencing and association analysis of the KALRN and EPHB1 genes and their contribution to schizophrenia susceptibility. Schizophr Bull 2012; 38: 552-560.
    • (2012) Schizophr Bull , vol.38 , pp. 552-560
    • Kushima, I.1    Nakamura, Y.2    Aleksic, B.3    Ikeda, M.4    Ito, Y.5    Shiino, T.6
  • 15
    • 84923250088 scopus 로고    scopus 로고
    • A sequence variant in human KALRN impairs protein function and coincides with reduced cortical thickness
    • Russell TA, Blizinsky KD, Cobia DJ, Cahill ME, Xie Z, Sweet RA et al. A sequence variant in human KALRN impairs protein function and coincides with reduced cortical thickness. Nat Commun 2014; 5: 4858.
    • (2014) Nat Commun , vol.5 , pp. 4858
    • Russell, T.A.1    Blizinsky, K.D.2    Cobia, D.J.3    Cahill, M.E.4    Xie, Z.5    Sweet, R.A.6
  • 17
    • 84942333302 scopus 로고    scopus 로고
    • IRSp53/BAIAP2 in dendritic spine development, NMDA receptor regulation, and psychiatric disorders
    • Kang J, Park H, Kim E. IRSp53/BAIAP2 in dendritic spine development, NMDA receptor regulation, and psychiatric disorders. Neuropharmacology 2016; 100: 27-39.
    • (2016) Neuropharmacology , vol.100 , pp. 27-39
    • Kang, J.1    Park, H.2    Kim, E.3
  • 19
    • 80051924099 scopus 로고    scopus 로고
    • Ultrastructural modifications of spine and synapse morphology by SAP97
    • Poglia L, Muller D, Nikonenko I. Ultrastructural modifications of spine and synapse morphology by SAP97. Hippocampus 2011; 21: 990-998.
    • (2011) Hippocampus , vol.21 , pp. 990-998
    • Poglia, L.1    Muller, D.2    Nikonenko, I.3
  • 20
    • 50649124440 scopus 로고    scopus 로고
    • An association analysis of synapseassociated protein 97 (SAP97) gene in schizophrenia
    • Sato J, Shimazu D, Yamamoto N, Nishikawa T. An association analysis of synapseassociated protein 97 (SAP97) gene in schizophrenia. J Neural Transm (Vienna) 2008; 115: 1355-1365.
    • (2008) J Neural Transm (Vienna) , vol.115 , pp. 1355-1365
    • Sato, J.1    Shimazu, D.2    Yamamoto, N.3    Nishikawa, T.4
  • 21
    • 84855455351 scopus 로고    scopus 로고
    • Further evidence for a male-selective genetic association of synapse-associated protein 97 (SAP97) gene with schizophrenia
    • Uezato A, Kimura-Sato J, Yamamoto N, Iijima Y, Kunugi H, Nishikawa T. Further evidence for a male-selective genetic association of synapse-associated protein 97 (SAP97) gene with schizophrenia. Behav Brain Funct 2012; 8: 2.
    • (2012) Behav Brain Funct , vol.8 , pp. 2
    • Uezato, A.1    Kimura-Sato, J.2    Yamamoto, N.3    Iijima, Y.4    Kunugi, H.5    Nishikawa, T.6
  • 22
    • 84920646061 scopus 로고    scopus 로고
    • Genetic risk for schizophrenia: Convergence on synaptic pathways involved in plasticity
    • Hall J, Trent S, Thomas KL, O'Donovan MC, Owen MJ. Genetic risk for schizophrenia: convergence on synaptic pathways involved in plasticity. Biol Psychiatry 2015; 77: 52-58.
    • (2015) Biol Psychiatry , vol.77 , pp. 52-58
    • Hall, J.1    Trent, S.2    Thomas, K.L.3    O'Donovan, M.C.4    Owen, M.J.5
  • 23
    • 69249100460 scopus 로고    scopus 로고
    • Experience-dependent structural synaptic plasticity in the mammalian brain
    • Holtmaat A, Svoboda K. Experience-dependent structural synaptic plasticity in the mammalian brain. Nat Rev Neurosci 2009; 10: 647-658.
    • (2009) Nat Rev Neurosci , vol.10 , pp. 647-658
    • Holtmaat, A.1    Svoboda, K.2
  • 24
    • 84900558583 scopus 로고    scopus 로고
    • Spatiotemporal dynamics of dendritic spines in the living brain
    • Chen CC, Lu J, Zuo Y. Spatiotemporal dynamics of dendritic spines in the living brain. Front Neuroanat 2014; 8: 28.
    • (2014) Front Neuroanat , vol.8 , pp. 28
    • Chen, C.C.1    Lu, J.2    Zuo, Y.3
  • 25
    • 84879956588 scopus 로고    scopus 로고
    • Developmental vulnerability of synapses and circuits associated with neuropsychiatric disorders
    • Penzes P, Buonanno A, Passafaro M, Sala C, Sweet RA. Developmental vulnerability of synapses and circuits associated with neuropsychiatric disorders. J Neurochem 2013; 126: 165-182.
    • (2013) J Neurochem , vol.126 , pp. 165-182
    • Penzes, P.1    Buonanno, A.2    Passafaro, M.3    Sala, C.4    Sweet, R.A.5
  • 26
    • 79960925535 scopus 로고    scopus 로고
    • Functional mapping of single spines in cortical neurons in vivo
    • Chen X, Leischner U, Rochefort NL, Nelken I, Konnerth A. Functional mapping of single spines in cortical neurons in vivo. Nature 2011; 475: 501-505.
    • (2011) Nature , vol.475 , pp. 501-505
    • Chen, X.1    Leischner, U.2    Rochefort, N.L.3    Nelken, I.4    Konnerth, A.5
  • 27
    • 84926152584 scopus 로고    scopus 로고
    • Developmental regulation of human cortex transcription and its clinical relevance at single base resolution
    • Jaffe AE, Shin J, Collado-Torres L, Leek JT, Tao R, Li C et al. Developmental regulation of human cortex transcription and its clinical relevance at single base resolution. Nat Neurosci 2015; 18: 154-161.
    • (2015) Nat Neurosci , vol.18 , pp. 154-161
    • Jaffe, A.E.1    Shin, J.2    Collado-Torres, L.3    Leek, J.T.4    Tao, R.5    Li, C.6
  • 28
    • 41149140859 scopus 로고    scopus 로고
    • Epigenomic profiling reveals DNA-methylation changes associated with major psychosis
    • Mill J, Tang T, Kaminsky Z, Khare T, Yazdanpanah S, Bouchard L et al. Epigenomic profiling reveals DNA-methylation changes associated with major psychosis. Am J Hum Genet 2008; 82: 696-711.
    • (2008) Am J Hum Genet , vol.82 , pp. 696-711
    • Mill, J.1    Tang, T.2    Kaminsky, Z.3    Khare, T.4    Yazdanpanah, S.5    Bouchard, L.6
  • 29
    • 84899733036 scopus 로고    scopus 로고
    • The DNA methylome and transcriptome of different brain regions in schizophrenia and bipolar disorder
    • Xiao Y, Camarillo C, Ping Y, Arana TB, Zhao H, Thompson PM et al. The DNA methylome and transcriptome of different brain regions in schizophrenia and bipolar disorder. PLoS ONE 2014; 9: e95875.
    • (2014) PLoS ONE , vol.9 , pp. e95875
    • Xiao, Y.1    Camarillo, C.2    Ping, Y.3    Arana, T.B.4    Zhao, H.5    Thompson, P.M.6
  • 30
    • 47149112211 scopus 로고    scopus 로고
    • DNA methylation changes in schizophrenia and bipolar disorder
    • Connor CM, Akbarian S. DNA methylation changes in schizophrenia and bipolar disorder. Epigenetics 2008; 3: 55-58.
    • (2008) Epigenetics , vol.3 , pp. 55-58
    • Connor, C.M.1    Akbarian, S.2
  • 31
    • 84953729873 scopus 로고    scopus 로고
    • Methylation QTLs in the developing brain and their enrichment in schizophrenia risk loci
    • Hannon E, Spiers H, Viana J, Pidsley R, Burrage J, Murphy TM et al. Methylation QTLs in the developing brain and their enrichment in schizophrenia risk loci. Nat Neurosci 2016; 19: 48-54.
    • (2016) Nat Neurosci , vol.19 , pp. 48-54
    • Hannon, E.1    Spiers, H.2    Viana, J.3    Pidsley, R.4    Burrage, J.5    Murphy, T.M.6
  • 32
    • 84953762043 scopus 로고    scopus 로고
    • Mapping DNA methylation across development, genotype and schizophrenia in the human frontal cortex
    • Jaffe AE, Gao Y, Deep-Soboslay A, Tao R, Hyde TM, Weinberger DR et al. Mapping DNA methylation across development, genotype and schizophrenia in the human frontal cortex. Nat Neurosci 2016; 19: 40-47.
    • (2016) Nat Neurosci , vol.19 , pp. 40-47
    • Jaffe, A.E.1    Gao, Y.2    Deep-Soboslay, A.3    Tao, R.4    Hyde, T.M.5    Weinberger, D.R.6
  • 33
    • 84906270288 scopus 로고    scopus 로고
    • DNA methylation changes in the postmortem dorsolateral prefrontal cortex of patients with schizophrenia
    • Numata S, Ye T, Herman M, Lipska BK. DNA methylation changes in the postmortem dorsolateral prefrontal cortex of patients with schizophrenia. Front Genet 2014; 5: 280.
    • (2014) Front Genet , vol.5 , pp. 280
    • Numata, S.1    Ye, T.2    Herman, M.3    Lipska, B.K.4
  • 34
    • 84931073968 scopus 로고    scopus 로고
    • Circuit-and diagnosis-specific DNA methylation changes at gamma-aminobutyric acid-related genes in postmortem human hippocampus in schizophrenia and bipolar disorder
    • Ruzicka WB, Subburaju S, Benes FM. Circuit-and diagnosis-specific DNA methylation changes at gamma-aminobutyric acid-related genes in postmortem human hippocampus in schizophrenia and bipolar disorder. JAMA Psychiatry 2015; 72: 541-551.
    • (2015) JAMA Psychiatry , vol.72 , pp. 541-551
    • Ruzicka, W.B.1    Subburaju, S.2    Benes, F.M.3
  • 35
    • 84929193210 scopus 로고    scopus 로고
    • Altered glutamate protein co-expression network topology linked to spine loss in the auditory cortex of schizophrenia
    • MacDonald ML, Ding Y, Newman J, Hemby S, Penzes P, Lewis DA et al. Altered glutamate protein co-expression network topology linked to spine loss in the auditory cortex of schizophrenia. Biol Psychiatry 2015; 77: 959-968.
    • (2015) Biol Psychiatry , vol.77 , pp. 959-968
    • MacDonald, M.L.1    Ding, Y.2    Newman, J.3    Hemby, S.4    Penzes, P.5    Lewis, D.A.6
  • 37
    • 46249088370 scopus 로고    scopus 로고
    • Lin SM. Lumi: A pipeline for processing Illumina microarray
    • Du P, Kibbe WA, Lin SM. lumi: a pipeline for processing Illumina microarray. Bioinformatics 2008; 24: 1547-1548.
    • (2008) Bioinformatics , vol.24 , pp. 1547-1548
    • Du, P.1    Kibbe, W.A.2
  • 38
    • 84872564830 scopus 로고    scopus 로고
    • A beta-mixture quantile normalization method for correcting probe design bias in Illumina Infinium 450 k DNA methylation data
    • Teschendorff AE, Marabita F, Lechner M, Bartlett T, Tegner J, Gomez-Cabrero D et al. A beta-mixture quantile normalization method for correcting probe design bias in Illumina Infinium 450 k DNA methylation data. Bioinformatics 2013; 29: 189-196.
    • (2013) Bioinformatics , vol.29 , pp. 189-196
    • Teschendorff, A.E.1    Marabita, F.2    Lechner, M.3    Bartlett, T.4    Tegner, J.5    Gomez-Cabrero, D.6
  • 40
  • 42
    • 77956874880 scopus 로고    scopus 로고
    • Toward a more uniform sampling of human genetic diversity: A survey of worldwide populations by high-density genotyping
    • Xing J, Watkins WS, Shlien A, Walker E, Huff CD, Witherspoon DJ et al. Toward a more uniform sampling of human genetic diversity: a survey of worldwide populations by high-density genotyping. Genomics 2010; 96: 199-210.
    • (2010) Genomics , vol.96 , pp. 199-210
    • Xing, J.1    Watkins, W.S.2    Shlien, A.3    Walker, E.4    Huff, C.D.5    Witherspoon, D.J.6
  • 43
    • 84886111619 scopus 로고    scopus 로고
    • DNA methylation age of human tissues and cell types
    • Horvath S. DNA methylation age of human tissues and cell types. Genome Biol 2013; 14: R115.
    • (2013) Genome Biol , vol.14 , pp. R115
    • Horvath, S.1
  • 44
    • 84878798054 scopus 로고    scopus 로고
    • Epigenetic determinants of healthy and diseased brain aging and cognition
    • Akbarian S, Beeri MS, Haroutunian V. Epigenetic determinants of healthy and diseased brain aging and cognition. JAMA Neurol 2013; 70: 711-718.
    • (2013) JAMA Neurol , vol.70 , pp. 711-718
    • Akbarian, S.1    Beeri, M.S.2    Haroutunian, V.3
  • 45
    • 84941313544 scopus 로고    scopus 로고
    • Hypermethylation of BDNF and SST genes in the orbital frontal cortex of older individuals: A putative mechanism for declining gene expression with age
    • McKinney BC, Lin CW, Oh H, Tseng GC, Lewis DA, Sibille E. Hypermethylation of BDNF and SST genes in the orbital frontal cortex of older individuals: a putative mechanism for declining gene expression with age. Neuropsychopharmacology 2015; 40: 2604-2613.
    • (2015) Neuropsychopharmacology , vol.40 , pp. 2604-2613
    • McKinney, B.C.1    Lin, C.W.2    Oh, H.3    Tseng, G.C.4    Lewis, D.A.5    Sibille, E.6
  • 46
    • 0036146670 scopus 로고    scopus 로고
    • The human brain revisited: Opportunities and challenges in postmortem studies of psychiatric disorders
    • Lewis DA. The human brain revisited: opportunities and challenges in postmortem studies of psychiatric disorders. Neuropsychopharmacology 2002; 26: 143-154.
    • (2002) Neuropsychopharmacology , vol.26 , pp. 143-154
    • Lewis, D.A.1
  • 48
    • 84891766375 scopus 로고    scopus 로고
    • Differences in DNA methylation between human neuronal and glial cells are concentrated in enhancers and non-CpG sites
    • Kozlenkov A, Roussos P, Timashpolsky A, Barbu M, Rudchenko S, Bibikova M et al. Differences in DNA methylation between human neuronal and glial cells are concentrated in enhancers and non-CpG sites. Nucleic Acids Res 2014; 42: 109-127.
    • (2014) Nucleic Acids Res , vol.42 , pp. 109-127
    • Kozlenkov, A.1    Roussos, P.2    Timashpolsky, A.3    Barbu, M.4    Rudchenko, S.5    Bibikova, M.6
  • 49
    • 84875700729 scopus 로고    scopus 로고
    • A cell epigenotype specific model for the correction of brain cellular heterogeneity bias and its application to age, brain region and major depression
    • Guintivano J, Aryee MJ, Kaminsky ZA. A cell epigenotype specific model for the correction of brain cellular heterogeneity bias and its application to age, brain region and major depression. Epigenetics 2013; 8: 290-302.
    • (2013) Epigenetics , vol.8 , pp. 290-302
    • Guintivano, J.1    Aryee, M.J.2    Kaminsky, Z.A.3
  • 51
    • 77957895378 scopus 로고    scopus 로고
    • Autistic and psychiatric findings associated with the 3q29 microdeletion syndrome: Case report and review
    • Quintero-Rivera F, Sharifi-Hannauer P, Martinez-Agosto JA. Autistic and psychiatric findings associated with the 3q29 microdeletion syndrome: case report and review. Am J Med Genet A 2010; 152A: 2459-2467.
    • (2010) Am J Med Genet A , vol.152 , pp. 2459-2467
    • Quintero-Rivera, F.1    Sharifi-Hannauer, P.2    Martinez-Agosto, J.A.3
  • 52
    • 84892183692 scopus 로고    scopus 로고
    • The anchoring protein SAP97 influences the trafficking and localisation of multiple membrane channels
    • Fourie C, Li D, Montgomery JM. The anchoring protein SAP97 influences the trafficking and localisation of multiple membrane channels. Biochim Biophys Acta 2014; 1838: 589-594.
    • (2014) Biochim Biophys Acta , vol.1838 , pp. 589-594
    • Fourie, C.1    Li, D.2    Montgomery, J.M.3
  • 53
    • 77956132014 scopus 로고    scopus 로고
    • Epigenetic regulation of neuronal dendrite and dendritic spine development
    • Smrt RD, Zhao X. Epigenetic regulation of neuronal dendrite and dendritic spine development. Front Biol (Beijing) 2010; 5: 304-323.
    • (2010) Front Biol (Beijing) , vol.5 , pp. 304-323
    • Smrt, R.D.1    Zhao, X.2
  • 54
    • 77956139754 scopus 로고    scopus 로고
    • Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens
    • LaPlant Q, Vialou V, Covington HE 3rd, Dumitriu D, Feng J, Warren BL et al. Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens. Nat Neurosci 2010; 13: 1137-1143.
    • (2010) Nat Neurosci , vol.13 , pp. 1137-1143
    • LaPlant, Q.1    Vialou, V.2    Covington, H.E.3    Dumitriu, D.4    Feng, J.5    Warren, B.L.6
  • 56
    • 84896732939 scopus 로고    scopus 로고
    • Methylome-wide association study of schizophrenia: Identifying blood biomarker signatures of environmental insults
    • Aberg KA, McClay JL, Nerella S, Clark S, Kumar G, Chen W et al. Methylome-wide association study of schizophrenia: identifying blood biomarker signatures of environmental insults. JAMA Psychiatry 2014; 71: 255-264.
    • (2014) JAMA Psychiatry , vol.71 , pp. 255-264
    • Aberg, K.A.1    McClay, J.L.2    Nerella, S.3    Clark, S.4    Kumar, G.5    Chen, W.6
  • 58
    • 84875422528 scopus 로고    scopus 로고
    • Comprehensive DNA methylation analysis of peripheral blood cells derived from patients with first-episode schizophrenia
    • Nishioka M, Bundo M, Koike S, Takizawa R, Kakiuchi C, Araki T et al. Comprehensive DNA methylation analysis of peripheral blood cells derived from patients with first-episode schizophrenia. J Hum Genet 2013; 58: 91-97.
    • (2013) J Hum Genet , vol.58 , pp. 91-97
    • Nishioka, M.1    Bundo, M.2    Koike, S.3    Takizawa, R.4    Kakiuchi, C.5    Araki, T.6
  • 59
    • 84947019946 scopus 로고    scopus 로고
    • Antipsychotic drugs attenuate aberrant DNA methylation of DTNBP1 (dysbindin) promoter in saliva and post-mortem brain of patients with schizophrenia and Psychotic bipolar disorder
    • Abdolmaleky HM, Pajouhanfar S, Faghankhani M, Joghataei MT, Mostafavi A, Thiagalingam S. Antipsychotic drugs attenuate aberrant DNA methylation of DTNBP1 (dysbindin) promoter in saliva and post-mortem brain of patients with schizophrenia and Psychotic bipolar disorder. Am J Med Genet B Neuropsychiatr Genet 2015; 168: 687-696.
    • (2015) Am J Med Genet B Neuropsychiatr Genet , vol.168 , pp. 687-696
    • Abdolmaleky, H.M.1    Pajouhanfar, S.2    Faghankhani, M.3    Joghataei, M.T.4    Mostafavi, A.5    Thiagalingam, S.6
  • 60
    • 84863986133 scopus 로고    scopus 로고
    • Functions of DNA methylation: Islands, start sites, gene bodies and beyond
    • Jones PA. Functions of DNA methylation: islands, start sites, gene bodies and beyond. Nat Rev Genet 2012; 13: 484-492.
    • (2012) Nat Rev Genet , vol.13 , pp. 484-492
    • Jones, P.A.1
  • 61
    • 84884759753 scopus 로고    scopus 로고
    • Intragenic DNA methylation in transcriptional regulation, normal differentiation and cancer
    • Kulis M, Queiros AC, Beekman R, Martin-Subero JI. Intragenic DNA methylation in transcriptional regulation, normal differentiation and cancer. Biochim Biophys Acta 2013; 1829: 1161-1174.
    • (2013) Biochim Biophys Acta , vol.1829 , pp. 1161-1174
    • Kulis, M.1    Queiros, A.C.2    Beekman, R.3    Martin-Subero, J.I.4
  • 62
    • 84928761297 scopus 로고    scopus 로고
    • The alternative role of DNA methylation in splicing regulation
    • Lev Maor G, Yearim A, Ast G. The alternative role of DNA methylation in splicing regulation. Trends Genet 2015; 31: 274-280.
    • (2015) Trends Genet , vol.31 , pp. 274-280
    • Lev Maor, G.1    Yearim, A.2    Ast, G.3
  • 64
    • 84895801889 scopus 로고    scopus 로고
    • Genomic patterns and context specific interpretation of DNA methylation
    • Baubec T, Schubeler D. Genomic patterns and context specific interpretation of DNA methylation. Curr Opin Genet Dev 2014; 25: 85-92.
    • (2014) Curr Opin Genet Dev , vol.25 , pp. 85-92
    • Baubec, T.1    Schubeler, D.2
  • 67
    • 84922311751 scopus 로고    scopus 로고
    • Neighboring gene regulation by antisense long non-coding RNAs
    • Villegas VE, Zaphiropoulos PG. Neighboring gene regulation by antisense long non-coding RNAs. Int J Mol Sci 2015; 16: 3251-3266.
    • (2015) Int J Mol Sci , vol.16 , pp. 3251-3266
    • Villegas, V.E.1    Zaphiropoulos, P.G.2
  • 69
    • 84960799274 scopus 로고    scopus 로고
    • Altered expression of CDC42 signaling pathway components in cortical layer 3 pyramidal cells in schizophrenia
    • Datta D, Arion D, Corradi JP, Lewis DA. Altered expression of CDC42 signaling pathway components in cortical layer 3 pyramidal cells in schizophrenia. Biol Psychiatry 2015; 78: 775-785.
    • (2015) Biol Psychiatry , vol.78 , pp. 775-785
    • Datta, D.1    Arion, D.2    Corradi, J.P.3    Lewis, D.A.4
  • 70
    • 84963801071 scopus 로고    scopus 로고
    • Substantial DNA methylation differences between two major neuronal subtypes in human brain
    • Kozlenkov A, Wang M, Roussos P, Rudchenko S, Barbu M, Bibikova M et al. Substantial DNA methylation differences between two major neuronal subtypes in human brain. Nucleic Acids Res 2016; 44: 2593-2612.
    • (2016) Nucleic Acids Res , vol.44 , pp. 2593-2612
    • Kozlenkov, A.1    Wang, M.2    Roussos, P.3    Rudchenko, S.4    Barbu, M.5    Bibikova, M.6
  • 71
    • 79960936836 scopus 로고    scopus 로고
    • Region-specific in situ hybridization-guided lasercapture microdissection on postmortem human brain tissue coupled with gene expression quantification
    • Bernard R, Burke S, Kerman IA. Region-specific in situ hybridization-guided lasercapture microdissection on postmortem human brain tissue coupled with gene expression quantification. Methods Mol Biol 2011; 755: 345-361.
    • (2011) Methods Mol Biol , vol.755 , pp. 345-361
    • Bernard, R.1    Burke, S.2    Kerman, I.A.3


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