Hypermethylation of BDNF and SST Genes in the Orbital Frontal Cortex of Older Individuals: A Putative Mechanism for Declining Gene Expression with Age

Neuropsychopharmacology

Volumn 40, Issue 11, 2015, Pages 2604-2613

  McKinney, Brandon C ^a   Lin, Chien Wei ^b   Oh, Hyunjung ^a,c   Tseng, George C ^b   Lewis, David A ^a,c   Sibille, Etienne ^a,c,d  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

^d CENTRE FOR ADDICTION AND MENTAL HEALTH   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; BRAIN DERIVED NEUROTROPHIC FACTOR; SOMATOSTATIN; BRAIN-DERIVED NEUROTROPHIC FACTOR, HUMAN; MESSENGER RNA;

ADULT; AGE; AGED; ARTICLE; BRAIN CORTEX; CORRELATIONAL STUDY; DNA METHYLATION; EXON; FEMALE; GENE EXPRESSION; HUMAN; INTRON; MALE; ORBITAL CORTEX; PRIORITY JOURNAL; PROTEIN EXPRESSION; AGING; BRAIN; COHORT ANALYSIS; GENE EXPRESSION PROFILING; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MIDDLE AGED; PHYSIOLOGY; PREFRONTAL CORTEX;

ADULT; AGED; AGING; BRAIN; BRAIN-DERIVED NEUROTROPHIC FACTOR; COHORT STUDIES; DNA METHYLATION; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMANS; MALE; MIDDLE AGED; PREFRONTAL CORTEX; RNA, MESSENGER; SOMATOSTATIN;

EID: 84941313544     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2015.107     Document Type: Article

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