메뉴 건너뛰기




Volumn 126, Issue 2, 2013, Pages 165-182

Developmental vulnerability of synapses and circuits associated with neuropsychiatric disorders

Author keywords

Alzheimer's disease; autism; dendritic spine; dopamine; ErbB4; GABAergic interneuron

Indexed keywords

ACYLTRANSFERASE; AMYLOID BETA PROTEIN; DISRUPTED IN SCHIZOPHRENIA 1 PROTEIN; DOPAMINE; EPIDERMAL GROWTH FACTOR RECEPTOR 4; INTERLEUKIN 1 RECEPTOR ACCESSORY PROTEIN; INTERLEUKIN 1 RECEPTOR ACCESSORY PROTEIN LIKE 1; MEMBRANE PROTEIN; NEU DIFFERENTIATION FACTOR; NUCLEAR PROTEIN; OLIGOPHRENIN 1; PROTEIN DGCR8; PROTEIN TSPAN7; PROTEIN ZDHHC8; RHO FACTOR; SCAFFOLD PROTEIN; SHANK PROTEIN; TETRASPANIN; UNCLASSIFIED DRUG;

EID: 84879956588     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.12261     Document Type: Review
Times cited : (99)

References (217)
  • 2
    • 33747872904 scopus 로고    scopus 로고
    • Molecular and cellular mechanisms of altered GAD1/GAD67 expression in schizophrenia and related disorders
    • Akbarian S., and, Huang H. S., (2006) Molecular and cellular mechanisms of altered GAD1/GAD67 expression in schizophrenia and related disorders. Brain Res. Rev. 52, 293-304.
    • (2006) Brain Res. Rev. , vol.52 , pp. 293-304
    • Akbarian, S.1    Huang, H.S.2
  • 3
    • 0028948389 scopus 로고
    • Gene expression for glutamic acid decarboxylase is reduced without loss of neurons in prefrontal cortex of schizophrenics
    • Akbarian S., Kim J. J., Potkin S. G., Hagman J. O., Tafazzoli A., Bunney W. E. Jr, and, Jones E. G., (1995) Gene expression for glutamic acid decarboxylase is reduced without loss of neurons in prefrontal cortex of schizophrenics. Arch. Gen. Psychiatry 52, 258-266.
    • (1995) Arch. Gen. Psychiatry , vol.52 , pp. 258-266
    • Akbarian, S.1    Kim, J.J.2    Potkin, S.G.3    Hagman, J.O.4    Tafazzoli, A.5    Bunney, Jr.W.E.6    Jones, E.G.7
  • 4
    • 34249933552 scopus 로고    scopus 로고
    • Anatomical and physiological plasticity of dendritic spines
    • Alvarez V. A., and, Sabatini B. L., (2007) Anatomical and physiological plasticity of dendritic spines. Annu. Rev. Neurosci. 30, 79-97.
    • (2007) Annu. Rev. Neurosci. , vol.30 , pp. 79-97
    • Alvarez, V.A.1    Sabatini, B.L.2
  • 7
    • 79951813355 scopus 로고    scopus 로고
    • Differential effects of prenatal and postnatal expressions of mutant human DISC1 on neurobehavioral phenotypes in transgenic mice: Evidence for neurodevelopmental origin of major psychiatric disorders
    • Ayhan Y., Abazyan B., and, Nomura J., et al,. (2011) Differential effects of prenatal and postnatal expressions of mutant human DISC1 on neurobehavioral phenotypes in transgenic mice: evidence for neurodevelopmental origin of major psychiatric disorders. Mol. Psychiatry 16, 293-306.
    • (2011) Mol. Psychiatry , vol.16 , pp. 293-306
    • Ayhan, Y.1    Abazyan, B.2    Nomura, J.3
  • 9
    • 34147113363 scopus 로고    scopus 로고
    • Dendritic and spinal pathology in the acoustic cortex in Alzheimer's disease: Morphological and morphometric estimation by Golgi technique and electron microscopy
    • Baloyannis S. J., Costa V., Mauroudis I., Psaroulis D., Manolides S. L., and, Manolides L. S., (2007) Dendritic and spinal pathology in the acoustic cortex in Alzheimer's disease: morphological and morphometric estimation by Golgi technique and electron microscopy. Acta Otolaryngol. 127, 351-354.
    • (2007) Acta Otolaryngol. , vol.127 , pp. 351-354
    • Baloyannis, S.J.1    Costa, V.2    Mauroudis, I.3    Psaroulis, D.4    Manolides, S.L.5    Manolides, L.S.6
  • 11
    • 0025185109 scopus 로고
    • Auditory hallucinations and smaller superior temporal gyral volume in schizophrenia
    • Barta P. E., Pearlson G. D., Powers R. E., Richards S. S., and, Tune L. E., (1990) Auditory hallucinations and smaller superior temporal gyral volume in schizophrenia. Am. J. Psychiatry 147, 1457-1462.
    • (1990) Am. J. Psychiatry , vol.147 , pp. 1457-1462
    • Barta, P.E.1    Pearlson, G.D.2    Powers, R.E.3    Richards, S.S.4    Tune, L.E.5
  • 12
    • 33845794324 scopus 로고    scopus 로고
    • Synaptic mechanisms of synchronized gamma oscillations in inhibitory interneuron networks
    • Bartos M., Vida I., and, Jonas P., (2007) Synaptic mechanisms of synchronized gamma oscillations in inhibitory interneuron networks. Nat. Rev. Neurosci. 8, 45-56.
    • (2007) Nat. Rev. Neurosci. , vol.8 , pp. 45-56
    • Bartos, M.1    Vida, I.2    Jonas, P.3
  • 13
    • 84858684894 scopus 로고    scopus 로고
    • The X-Linked Intellectual Disability Protein TSPAN7 Regulates Excitatory Synapse Development and AMPAR Trafficking
    • Bassani S., Cingolani L. A., Valnegri P., Folci A., Zapata J., Gianfelice A., Sala C., Goda Y., and, Passafaro M., (2012) The X-Linked Intellectual Disability Protein TSPAN7 Regulates Excitatory Synapse Development and AMPAR Trafficking. Neuron 73, 1143-1158.
    • (2012) Neuron , vol.73 , pp. 1143-1158
    • Bassani, S.1    Cingolani, L.A.2    Valnegri, P.3    Folci, A.4    Zapata, J.5    Gianfelice, A.6    Sala, C.7    Goda, Y.8    Passafaro, M.9
  • 14
    • 34248995257 scopus 로고    scopus 로고
    • The action potential in mammalian central neurons
    • Bean B. P., (2007) The action potential in mammalian central neurons. Nat. Rev. Neurosci. 8, 451-465.
    • (2007) Nat. Rev. Neurosci. , vol.8 , pp. 451-465
    • Bean, B.P.1
  • 15
    • 73949136265 scopus 로고    scopus 로고
    • Postnatal NMDA receptor ablation in corticolimbic interneurons confers schizophrenia-like phenotypes
    • Belforte J. E., Zsiros V., Sklar E. R., Jiang Z., Yu G., Li Y., Quinlan E. M., and, Nakazawa K., (2010) Postnatal NMDA receptor ablation in corticolimbic interneurons confers schizophrenia-like phenotypes. Nat. Neurosci. 13, 76-83.
    • (2010) Nat. Neurosci. , vol.13 , pp. 76-83
    • Belforte, J.E.1    Zsiros, V.2    Sklar, E.R.3    Jiang, Z.4    Yu, G.5    Li, Y.6    Quinlan, E.M.7    Nakazawa, K.8
  • 16
    • 84858146355 scopus 로고    scopus 로고
    • NAAG, NMDA receptor and psychosis
    • Bergeron R., and, Coyle J. T., (2012) NAAG, NMDA receptor and psychosis. Curr. Med. Chem. 19, 1360-1364.
    • (2012) Curr. Med. Chem. , vol.19 , pp. 1360-1364
    • Bergeron, R.1    Coyle, J.T.2
  • 17
    • 77952827032 scopus 로고    scopus 로고
    • Mutations in the SHANK2 synaptic scaffolding gene in autism spectrum disorder and mental retardation
    • Berkel S., Marshall C. R., Weiss B., et al,. (2010) Mutations in the SHANK2 synaptic scaffolding gene in autism spectrum disorder and mental retardation. Nat. Genet. 42, 489-491.
    • (2010) Nat. Genet. , vol.42 , pp. 489-491
    • Berkel, S.1    Marshall, C.R.2    Weiss, B.3
  • 21
    • 17144466355 scopus 로고    scopus 로고
    • Differential expression and dendritic transcript localization of Shank family members: Identification of a dendritic targeting element in the 3′ untranslated region of Shank1 mRNA
    • Bockers T. M., Segger-Junius M., Iglauer P., Bockmann J., Gundelfinger E. D., Kreutz M. R., Richter D., Kindler S., and, Kreienkamp H. J., (2004) Differential expression and dendritic transcript localization of Shank family members: identification of a dendritic targeting element in the 3′ untranslated region of Shank1 mRNA. Mol. Cell. Neurosci. 26, 182-190.
    • (2004) Mol. Cell. Neurosci. , vol.26 , pp. 182-190
    • Bockers, T.M.1    Segger-Junius, M.2    Iglauer, P.3    Bockmann, J.4    Gundelfinger, E.D.5    Kreutz, M.R.6    Richter, D.7    Kindler, S.8    Kreienkamp, H.J.9
  • 23
    • 80054889797 scopus 로고    scopus 로고
    • Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication
    • Bozdagi O., Sakurai T., Papapetrou D., et al,. (2010) Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication. Mol. Autism 1, 15.
    • (2010) Mol. Autism , vol.1 , pp. 15
    • Bozdagi, O.1    Sakurai, T.2    Papapetrou, D.3
  • 24
    • 50849127099 scopus 로고    scopus 로고
    • Neuroanatomical correlates of neuropsychiatric symptoms in Alzheimer's disease
    • Bruen P. D., McGeown W. J., Shanks M. F., and, Venneri A., (2008) Neuroanatomical correlates of neuropsychiatric symptoms in Alzheimer's disease. Brain 131, 2455-2463.
    • (2008) Brain , vol.131 , pp. 2455-2463
    • Bruen, P.D.1    McGeown, W.J.2    Shanks, M.F.3    Venneri, A.4
  • 25
    • 77956647781 scopus 로고    scopus 로고
    • The neuregulin signaling pathway and schizophrenia: From genes to synapses and neural circuits
    • Buonanno A., (2010) The neuregulin signaling pathway and schizophrenia: from genes to synapses and neural circuits. Brain Res. Bull. 83, 122-131.
    • (2010) Brain Res. Bull. , vol.83 , pp. 122-131
    • Buonanno, A.1
  • 26
    • 0035368610 scopus 로고    scopus 로고
    • Neuregulin and ErbB receptor signaling pathways in the nervous system
    • Buonanno A., and, Fischbach G. D., (2001) Neuregulin and ErbB receptor signaling pathways in the nervous system. Curr. Opin. Neurobiol. 11, 287-296.
    • (2001) Curr. Opin. Neurobiol. , vol.11 , pp. 287-296
    • Buonanno, A.1    Fischbach, G.D.2
  • 27
    • 58949088309 scopus 로고    scopus 로고
    • Contact in the genetics of autism and schizophrenia
    • Burbach J. P., and, van der Zwaag B., (2009) Contact in the genetics of autism and schizophrenia. Trends Neurosci. 32, 69-72.
    • (2009) Trends Neurosci. , vol.32 , pp. 69-72
    • Burbach, J.P.1    Van Der Zwaag, B.2
  • 28
    • 69149090572 scopus 로고    scopus 로고
    • Kalirin regulates cortical spine morphogenesis and disease-related behavioral phenotypes
    • Cahill M. E., Xie Z., Day M., et al,. (2009) Kalirin regulates cortical spine morphogenesis and disease-related behavioral phenotypes. Proc. Natl Acad. Sci. USA 106, 13058-13063.
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 13058-13063
    • Cahill, M.E.1    Xie, Z.2    Day, M.3
  • 29
    • 0032819848 scopus 로고    scopus 로고
    • A new member of the IL-1 receptor family highly expressed in hippocampus and involved in X-linked mental retardation
    • Carrie A., Jun L., Bienvenu T., et al,. (1999) A new member of the IL-1 receptor family highly expressed in hippocampus and involved in X-linked mental retardation. Nat. Genet. 23, 25-31.
    • (1999) Nat. Genet. , vol.23 , pp. 25-31
    • Carrie, A.1    Jun, L.2    Bienvenu, T.3
  • 31
    • 84866778001 scopus 로고    scopus 로고
    • GABAergic circuit dysfunctions in neurodevelopmental disorders
    • Chattopadhyaya B., and, Cristo G. D., (2012) GABAergic circuit dysfunctions in neurodevelopmental disorders. Front. Psychiatry 3, 51.
    • (2012) Front. Psychiatry , vol.3 , pp. 51
    • Chattopadhyaya, B.1    Cristo, G.D.2
  • 32
    • 49049113745 scopus 로고    scopus 로고
    • Type III neuregulin-1 is required for normal sensorimotor gating, memory-related behaviors, and corticostriatal circuit components
    • Chen Y. J., Johnson M. A., Lieberman M. D., et al,. (2008) Type III neuregulin-1 is required for normal sensorimotor gating, memory-related behaviors, and corticostriatal circuit components. J. Neurosci. 28, 6872-6883.
    • (2008) J. Neurosci. , vol.28 , pp. 6872-6883
    • Chen, Y.J.1    Johnson, M.A.2    Lieberman, M.D.3
  • 33
    • 77954510804 scopus 로고    scopus 로고
    • Intramembranous valine linked to schizophrenia is required for neuregulin 1 regulation of the morphological development of cortical neurons
    • Chen Y., Hancock M. L., Role L. W., and, Talmage D. A., (2010) Intramembranous valine linked to schizophrenia is required for neuregulin 1 regulation of the morphological development of cortical neurons. J. Neurosci. 30, 9199-9208.
    • (2010) J. Neurosci. , vol.30 , pp. 9199-9208
    • Chen, Y.1    Hancock, M.L.2    Role, L.W.3    Talmage, D.A.4
  • 35
    • 0028846119 scopus 로고
    • Synchronization of neuronal activity in hippocampus by individual GABAergic interneurons
    • Cobb S. R., Buhl E. H., Halasy K., Paulsen O., and, Somogyi P., (1995) Synchronization of neuronal activity in hippocampus by individual GABAergic interneurons. Nature 378, 75-78.
    • (1995) Nature , vol.378 , pp. 75-78
    • Cobb, S.R.1    Buhl, E.H.2    Halasy, K.3    Paulsen, O.4    Somogyi, P.5
  • 36
    • 33746056445 scopus 로고    scopus 로고
    • Investigation of autism and GABA receptor subunit genes in multiple ethnic groups
    • Collins A. L., Ma D., Whitehead P. L., et al,. (2006) Investigation of autism and GABA receptor subunit genes in multiple ethnic groups. Neurogenetics 7, 167-174.
    • (2006) Neurogenetics , vol.7 , pp. 167-174
    • Collins, A.L.1    Ma, D.2    Whitehead, P.L.3
  • 37
    • 34248145469 scopus 로고    scopus 로고
    • Gene expression profiling in Brodmann's area 46 from subjects with schizophrenia
    • Dean B., Keriakous D., Scarr E., and, Thomas E. A., (2007) Gene expression profiling in Brodmann's area 46 from subjects with schizophrenia. Aust. N. Z. J. Psychiatry 41, 308-320.
    • (2007) Aust. N. Z. J. Psychiatry , vol.41 , pp. 308-320
    • Dean, B.1    Keriakous, D.2    Scarr, E.3    Thomas, E.A.4
  • 39
    • 79959224807 scopus 로고    scopus 로고
    • Psychosis in Alzheimer's disease in the national Alzheimer's disease coordinating center uniform data set: Clinical correlates and association with apolipoprotein e1
    • DeMichele-Sweet M. A., Lopez O. L., and, Sweet R. A., (2011a) Psychosis in Alzheimer's disease in the national Alzheimer's disease coordinating center uniform data set: clinical correlates and association with apolipoprotein e1. Int. J. Alzheimers Dis. 2011, 926597.
    • (2011) Int. J. Alzheimers Dis. , vol.2011 , pp. 926597
    • Demichele-Sweet, M.A.1    Lopez, O.L.2    Sweet, R.A.3
  • 42
    • 84855793269 scopus 로고    scopus 로고
    • Increased expression of Kalirin-9 in the auditory cortex of schizophrenia subjects: Its role in dendritic pathology
    • Deo A. J., Cahill M. E., Li S., et al,. (2011) Increased expression of Kalirin-9 in the auditory cortex of schizophrenia subjects: Its role in dendritic pathology. Neurobiol. Dis. 45, 796-803.
    • (2011) Neurobiol. Dis. , vol.45 , pp. 796-803
    • Deo, A.J.1    Cahill, M.E.2    Li, S.3
  • 43
    • 0037223609 scopus 로고    scopus 로고
    • Dopamine genes and attention-deficit hyperactivity disorder: A review
    • DiMaio S., Grizenko N., and, Joober R., (2003) Dopamine genes and attention-deficit hyperactivity disorder: a review. J. Psychiatry Neurosci. 28, 27-38.
    • (2003) J. Psychiatry Neurosci. , vol.28 , pp. 27-38
    • Dimaio, S.1    Grizenko, N.2    Joober, R.3
  • 44
    • 33845889998 scopus 로고    scopus 로고
    • Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders
    • Durand C. M., Betancur C., Boeckers T. M., et al,. (2007) Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders. Nat. Genet. 39, 25-27.
    • (2007) Nat. Genet. , vol.39 , pp. 25-27
    • Durand, C.M.1    Betancur, C.2    Boeckers, T.M.3
  • 46
    • 0035147986 scopus 로고    scopus 로고
    • Temporal binding and the neural correlates of sensory awareness
    • Engel A. K., and, Singer W., (2001) Temporal binding and the neural correlates of sensory awareness. Trends Cogn. Sci. 5, 16-25.
    • (2001) Trends Cogn. Sci. , vol.5 , pp. 16-25
    • Engel, A.K.1    Singer, W.2
  • 47
    • 0037108019 scopus 로고    scopus 로고
    • Glutamic acid decarboxylase 65 and 67 kDa proteins are reduced in autistic parietal and cerebellar cortices
    • Fatemi S. H., Halt A. R., Stary J. M., Kanodia R., Schulz S. C., and, Realmuto G. R., (2002) Glutamic acid decarboxylase 65 and 67 kDa proteins are reduced in autistic parietal and cerebellar cortices. Biol. Psychiatry 52, 805-810.
    • (2002) Biol. Psychiatry , vol.52 , pp. 805-810
    • Fatemi, S.H.1    Halt, A.R.2    Stary, J.M.3    Kanodia, R.4    Schulz, S.C.5    Realmuto, G.R.6
  • 50
    • 79960224900 scopus 로고    scopus 로고
    • Regulation of long-term plasticity induction by the channel and C-terminal domains of GluN2 subunits
    • Fetterolf F., and, Foster K. A., (2011) Regulation of long-term plasticity induction by the channel and C-terminal domains of GluN2 subunits. Mol. Neurobiol. 44, 71-82.
    • (2011) Mol. Neurobiol. , vol.44 , pp. 71-82
    • Fetterolf, F.1    Foster, K.A.2
  • 51
    • 59749094475 scopus 로고    scopus 로고
    • Neuregulin-1 modulates hippocampal gamma oscillations: Implications for schizophrenia
    • Fisahn A., Neddens J., Yan L., and, Buonanno A., (2009) Neuregulin-1 modulates hippocampal gamma oscillations: implications for schizophrenia. Cereb. Cortex 19, 612-618.
    • (2009) Cereb. Cortex , vol.19 , pp. 612-618
    • Fisahn, A.1    Neddens, J.2    Yan, L.3    Buonanno, A.4
  • 52
    • 16444383812 scopus 로고    scopus 로고
    • Developmental profile of ErbB receptors in murine central nervous system: Implications for functional interactions
    • Fox I. J., and, Kornblum H. I., (2005) Developmental profile of ErbB receptors in murine central nervous system: implications for functional interactions. J. Neurosci. Res. 79, 584-597.
    • (2005) J. Neurosci. Res. , vol.79 , pp. 584-597
    • Fox, I.J.1    Kornblum, H.I.2
  • 53
    • 79955025731 scopus 로고    scopus 로고
    • Deletion of the immunoglobulin domain of IL1RAPL1 results in nonsyndromic X-linked intellectual disability associated with behavioral problems and mild dysmorphism
    • Franek K. J., Butler J., Johnson J., et al,. (2011) Deletion of the immunoglobulin domain of IL1RAPL1 results in nonsyndromic X-linked intellectual disability associated with behavioral problems and mild dysmorphism. Am. J. Med. Genet. A 155A, 1109-1114.
    • (2011) Am. J. Med. Genet. A , vol.155 A , pp. 1109-1114
    • Franek, K.J.1    Butler, J.2    Johnson, J.3
  • 54
    • 67651113905 scopus 로고    scopus 로고
    • Genome-wide association studies in ADHD
    • Franke B., Neale B. M., and, Faraone S. V., (2009) Genome-wide association studies in ADHD. Hum. Genet. 126, 13-50.
    • (2009) Hum. Genet. , vol.126 , pp. 13-50
    • Franke, B.1    Neale, B.M.2    Faraone, S.V.3
  • 55
    • 33846849432 scopus 로고    scopus 로고
    • Recruitment of parvalbumin-positive interneurons determines hippocampal function and associated behavior
    • Fuchs E. C., Zivkovic A. R., Cunningham M. O., et al,. (2007) Recruitment of parvalbumin-positive interneurons determines hippocampal function and associated behavior. Neuron 53, 591-604.
    • (2007) Neuron , vol.53 , pp. 591-604
    • Fuchs, E.C.1    Zivkovic, A.R.2    Cunningham, M.O.3
  • 56
    • 84859009895 scopus 로고    scopus 로고
    • Rare structural variation of synapse and neurotransmission genes in autism
    • Gai X., Xie H. M., Perin J. C., et al,. (2012) Rare structural variation of synapse and neurotransmission genes in autism. Mol. Psychiatry 17, 402-411.
    • (2012) Mol. Psychiatry , vol.17 , pp. 402-411
    • Gai, X.1    Xie, H.M.2    Perin, J.C.3
  • 57
    • 0034724391 scopus 로고    scopus 로고
    • The neuregulin receptor ErbB-4 interacts with PDZ-containing proteins at neuronal synapses
    • Garcia R. A., Vasudevan K., and, Buonanno A., (2000) The neuregulin receptor ErbB-4 interacts with PDZ-containing proteins at neuronal synapses. Proc. Natl Acad. Sci. USA 97, 3596-3601.
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 3596-3601
    • Garcia, R.A.1    Vasudevan, K.2    Buonanno, A.3
  • 58
    • 0028047856 scopus 로고
    • Anterograde and retrograde tracing of projections from the ventral tegmental area to the hippocampal formation in the rat
    • Gasbarri A., Packard M. G., Campana E., and, Pacitti C., (1994) Anterograde and retrograde tracing of projections from the ventral tegmental area to the hippocampal formation in the rat. Brain Res. Bull. 33, 445-452.
    • (1994) Brain Res. Bull. , vol.33 , pp. 445-452
    • Gasbarri, A.1    Packard, M.G.2    Campana, E.3    Pacitti, C.4
  • 59
  • 61
    • 0035938429 scopus 로고    scopus 로고
    • ErbB transmembrane tyrosine kinase receptors are differentially expressed throughout the adult rat central nervous system
    • Gerecke K. M., Wyss J. M., Karavanova I., Buonanno A., and, Carroll S. L., (2001) ErbB transmembrane tyrosine kinase receptors are differentially expressed throughout the adult rat central nervous system. J. Comp. Neurol. 433, 86-100.
    • (2001) J. Comp. Neurol. , vol.433 , pp. 86-100
    • Gerecke, K.M.1    Wyss, J.M.2    Karavanova, I.3    Buonanno, A.4    Carroll, S.L.5
  • 62
    • 79958035893 scopus 로고    scopus 로고
    • Rare de novo variants associated with autism implicate a large functional network of genes involved in formation and function of synapses
    • Gilman S. R., Iossifov I., Levy D., Ronemus M., Wigler M., and, Vitkup D., (2011) Rare de novo variants associated with autism implicate a large functional network of genes involved in formation and function of synapses. Neuron 70, 898-907.
    • (2011) Neuron , vol.70 , pp. 898-907
    • Gilman, S.R.1    Iossifov, I.2    Levy, D.3    Ronemus, M.4    Wigler, M.5    Vitkup, D.6
  • 63
    • 78650808443 scopus 로고    scopus 로고
    • Phenotypic variability and genetic susceptibility to genomic disorders
    • Girirajan S., and, Eichler E. E,. (2010) Phenotypic variability and genetic susceptibility to genomic disorders. Hum. Mol. Genet. 19, R176-R187.
    • (2010) Hum. Mol. Genet. , vol.19
    • Girirajan, S.1    Eichler, E.E.2
  • 64
    • 0033985644 scopus 로고    scopus 로고
    • Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia
    • Glantz L. A., and, Lewis D. A., (2000) Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia. Arch. Gen. Psychiatry 57, 65-73.
    • (2000) Arch. Gen. Psychiatry , vol.57 , pp. 65-73
    • Glantz, L.A.1    Lewis, D.A.2
  • 66
    • 54149109208 scopus 로고    scopus 로고
    • GABA neurons and the mechanisms of network oscillations: Implications for understanding cortical dysfunction in schizophrenia
    • Gonzalez-Burgos G., and, Lewis D. A., (2008) GABA neurons and the mechanisms of network oscillations: implications for understanding cortical dysfunction in schizophrenia. Schizophr. Bull. 34, 944-961.
    • (2008) Schizophr. Bull. , vol.34 , pp. 944-961
    • Gonzalez-Burgos, G.1    Lewis, D.A.2
  • 67
    • 84863201711 scopus 로고    scopus 로고
    • NMDA receptor hypofunction, parvalbumin-positive neurons, and cortical gamma oscillations in schizophrenia
    • Gonzalez-Burgos G., and, Lewis D. A., (2012) NMDA receptor hypofunction, parvalbumin-positive neurons, and cortical gamma oscillations in schizophrenia. Schizophr. Bull. 38, 950-957.
    • (2012) Schizophr. Bull. , vol.38 , pp. 950-957
    • Gonzalez-Burgos, G.1    Lewis, D.A.2
  • 68
    • 1842455769 scopus 로고    scopus 로고
    • The X-linked mental retardation protein oligophrenin-1 is required for dendritic spine morphogenesis
    • Govek E. E., Newey S. E., Akerman C. J., Cross J. R., Van der Veken L., and, Van Aelst L., (2004) The X-linked mental retardation protein oligophrenin-1 is required for dendritic spine morphogenesis. Nat. Neurosci. 7, 364-372.
    • (2004) Nat. Neurosci. , vol.7 , pp. 364-372
    • Govek, E.E.1    Newey, S.E.2    Akerman, C.J.3    Cross, J.R.4    Van Der Veken, L.5    Van Aelst, L.6
  • 69
    • 77957135975 scopus 로고    scopus 로고
    • Dopamine enhances the excitability of somatosensory thalamocortical neurons
    • Govindaiah G., Wang Y., and, Cox C. L., (2010) Dopamine enhances the excitability of somatosensory thalamocortical neurons. Neuroscience 170, 981-991.
    • (2010) Neuroscience , vol.170 , pp. 981-991
    • Govindaiah, G.1    Wang, Y.2    Cox, C.L.3
  • 70
    • 80051953863 scopus 로고    scopus 로고
    • Analysis of 94 candidate genes and 12 endophenotypes for schizophrenia from the Consortium on the Genetics of Schizophrenia
    • Greenwood T. A., Lazzeroni L. C., Murray S. S., et al,. (2011) Analysis of 94 candidate genes and 12 endophenotypes for schizophrenia from the Consortium on the Genetics of Schizophrenia. Am. J. Psychiat. 168, 930-946.
    • (2011) Am. J. Psychiat. , vol.168 , pp. 930-946
    • Greenwood, T.A.1    Lazzeroni, L.C.2    Murray, S.S.3
  • 71
    • 84855858727 scopus 로고    scopus 로고
    • Association analysis of 94 candidate genes and schizophrenia-related endophenotypes
    • Greenwood T. A., Light G. A., Swerdlow N. R., Radant A. D., and, Braff D. L., (2012) Association analysis of 94 candidate genes and schizophrenia-related endophenotypes. PLoS ONE 7, e29630.
    • (2012) PLoS ONE , vol.7
    • Greenwood, T.A.1    Light, G.A.2    Swerdlow, N.R.3    Radant, A.D.4    Braff, D.L.5
  • 72
    • 34247639567 scopus 로고    scopus 로고
    • Various dendritic abnormalities are associated with fibrillar amyloid deposits in Alzheimer's disease
    • Grutzendler J., Helmin K., Tsai J., and, Gan W. B., (2007) Various dendritic abnormalities are associated with fibrillar amyloid deposits in Alzheimer's disease. Ann. N. Y. Acad. Sci. 1097, 30-39.
    • (2007) Ann. N. Y. Acad. Sci. , vol.1097 , pp. 30-39
    • Grutzendler, J.1    Helmin, K.2    Tsai, J.3    Gan, W.B.4
  • 73
    • 69949177829 scopus 로고    scopus 로고
    • Recurrent rearrangements in synaptic and neurodevelopmental genes and shared biologic pathways in schizophrenia, autism, and mental retardation
    • Guilmatre A., Dubourg C., Mosca A. L., et al,. (2009) Recurrent rearrangements in synaptic and neurodevelopmental genes and shared biologic pathways in schizophrenia, autism, and mental retardation. Arch. Gen. Psychiatry 66, 947-956.
    • (2009) Arch. Gen. Psychiatry , vol.66 , pp. 947-956
    • Guilmatre, A.1    Dubourg, C.2    Mosca, A.L.3
  • 74
    • 34249036179 scopus 로고    scopus 로고
    • [3H]-flunitrazepam-labeled benzodiazepine binding sites in the hippocampal formation in autism: A multiple concentration autoradiographic study
    • Guptill J. T., Booker A. B., Gibbs T. T., Kemper T. L., Bauman M. L., and, Blatt G. J., (2007) [3H]-flunitrazepam-labeled benzodiazepine binding sites in the hippocampal formation in autism: a multiple concentration autoradiographic study. J. Autism Dev. Disord. 37, 911-920.
    • (2007) J. Autism Dev. Disord. , vol.37 , pp. 911-920
    • Guptill, J.T.1    Booker, A.B.2    Gibbs, T.T.3    Kemper, T.L.4    Bauman, M.L.5    Blatt, G.J.6
  • 75
    • 33845260095 scopus 로고    scopus 로고
    • A neuregulin 1 variant associated with abnormal cortical function and psychotic symptoms
    • Hall J., Whalley H. C., Job D. E., et al,. (2006) A neuregulin 1 variant associated with abnormal cortical function and psychotic symptoms. Nat. Neurosci. 9, 1477-1478.
    • (2006) Nat. Neurosci. , vol.9 , pp. 1477-1478
    • Hall, J.1    Whalley, H.C.2    Job, D.E.3
  • 76
    • 12344327212 scopus 로고    scopus 로고
    • Schizophrenia genes, gene expression, and neuropathology: On the matter of their convergence
    • image 45.
    • Harrison P. J., and, Weinberger D. R,. (2005) Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence. Mol. Psychiatry 10, 40-68; image 45.
    • (2005) Mol. Psychiatry , vol.10 , pp. 40-68
    • Harrison, P.J.1    Weinberger, D.R.2
  • 77
    • 77649192502 scopus 로고    scopus 로고
    • Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1
    • Hayashi-Takagi A., Takaki M., Graziane N., et al,. (2010) Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1. Nat. Neurosci. 13, 327-332.
    • (2010) Nat. Neurosci. , vol.13 , pp. 327-332
    • Hayashi-Takagi, A.1    Takaki, M.2    Graziane, N.3
  • 78
    • 28244449618 scopus 로고    scopus 로고
    • Human EEG gamma oscillations in neuropsychiatric disorders
    • Herrmann C. S., and, Demiralp T., (2005) Human EEG gamma oscillations in neuropsychiatric disorders. Clin. Neurophysiol. 116, 2719-2733.
    • (2005) Clin. Neurophysiol. , vol.116 , pp. 2719-2733
    • Herrmann, C.S.1    Demiralp, T.2
  • 79
    • 33745698814 scopus 로고    scopus 로고
    • Molecular mechanisms contributing to dendritic spine alterations in the prefrontal cortex of subjects with schizophrenia
    • Hill J. J., Hashimoto T., and, Lewis D. A., (2006) Molecular mechanisms contributing to dendritic spine alterations in the prefrontal cortex of subjects with schizophrenia. Mol. Psychiatry 11, 557-566.
    • (2006) Mol. Psychiatry , vol.11 , pp. 557-566
    • Hill, J.J.1    Hashimoto, T.2    Lewis, D.A.3
  • 80
    • 35148876475 scopus 로고    scopus 로고
    • Increased familial risk and genomewide significant linkage for Alzheimer's disease with psychosis
    • Hollingworth P., Hamshere M. L., Holmans P. A., et al,. (2007) Increased familial risk and genomewide significant linkage for Alzheimer's disease with psychosis. Am. J. Med. Genet. B Neuropsychiatr. Genet. 144B, 841-848.
    • (2007) Am. J. Med. Genet. B Neuropsychiatr. Genet. , vol.144 B , pp. 841-848
    • Hollingworth, P.1    Hamshere, M.L.2    Holmans, P.A.3
  • 81
    • 84869998396 scopus 로고    scopus 로고
    • Genome-wide association study of Alzheimer's disease with psychotic symptoms
    • Hollingworth P., Sweet R., Sims R., et al,. (2011) Genome-wide association study of Alzheimer's disease with psychotic symptoms. Mol. Psychiatry 17, 1316-1327.
    • (2011) Mol. Psychiatry , vol.17 , pp. 1316-1327
    • Hollingworth, P.1    Sweet, R.2    Sims, R.3
  • 82
    • 69249100460 scopus 로고    scopus 로고
    • Experience-dependent structural synaptic plasticity in the mammalian brain
    • Holtmaat A., and, Svoboda K., (2009) Experience-dependent structural synaptic plasticity in the mammalian brain. Nat. Rev. 10, 647-658.
    • (2009) Nat. Rev. , vol.10 , pp. 647-658
    • Holtmaat, A.1    Svoboda, K.2
  • 83
    • 33845411954 scopus 로고    scopus 로고
    • AMPAR removal underlies Abeta-induced synaptic depression and dendritic spine loss
    • Hsieh H., Boehm J., Sato C., Iwatsubo T., Tomita T., Sisodia S., and, Malinow R., (2006) AMPAR removal underlies Abeta-induced synaptic depression and dendritic spine loss. Neuron 52, 831-843.
    • (2006) Neuron , vol.52 , pp. 831-843
    • Hsieh, H.1    Boehm, J.2    Sato, C.3    Iwatsubo, T.4    Tomita, T.5    Sisodia, S.6    Malinow, R.7
  • 84
    • 0033697710 scopus 로고    scopus 로고
    • Regulation of neuregulin signaling by PSD-95 interacting with ErbB4 at CNS synapses
    • Huang Y. Z., Won S., Ali D. W., et al,. (2000) Regulation of neuregulin signaling by PSD-95 interacting with ErbB4 at CNS synapses. Neuron 26, 443-455.
    • (2000) Neuron , vol.26 , pp. 443-455
    • Huang, Y.Z.1    Won, S.2    Ali, D.W.3
  • 85
    • 39549100993 scopus 로고    scopus 로고
    • Smaller dendritic spines, weaker synaptic transmission, but enhanced spatial learning in mice lacking Shank1
    • Hung A. Y., Futai K., Sala C., et al,. (2008) Smaller dendritic spines, weaker synaptic transmission, but enhanced spatial learning in mice lacking Shank1. J. Neurosci. 28, 1697-1708.
    • (2008) J. Neurosci. , vol.28 , pp. 1697-1708
    • Hung, A.Y.1    Futai, K.2    Sala, C.3
  • 86
    • 77953615507 scopus 로고    scopus 로고
    • Altered Cortical CDC42 Signaling Pathways in Schizophrenia: Implications for Dendritic Spine Deficits
    • Ide M., and, Lewis D. A., (2010) Altered Cortical CDC42 Signaling Pathways in Schizophrenia: Implications for Dendritic Spine Deficits. Biol. Psychiatry 68, 25-32.
    • (2010) Biol. Psychiatry , vol.68 , pp. 25-32
    • Ide, M.1    Lewis, D.A.2
  • 87
    • 84867006349 scopus 로고    scopus 로고
    • Neuregulin directly decreases voltage-gated sodium current in hippocampal ErbB4-expressing interneurons
    • Janssen M. J., Leiva-Salcedo E., and, Buonanno A., (2012) Neuregulin directly decreases voltage-gated sodium current in hippocampal ErbB4-expressing interneurons. J. Neurosci. 32, 13889-13895.
    • (2012) J. Neurosci. , vol.32 , pp. 13889-13895
    • Janssen, M.J.1    Leiva-Salcedo, E.2    Buonanno, A.3
  • 88
    • 0038445711 scopus 로고    scopus 로고
    • Dopamine: A potential substrate for synaptic plasticity and memory mechanisms
    • Jay T. M., (2003) Dopamine: a potential substrate for synaptic plasticity and memory mechanisms. Prog. Neurobiol. 69, 375-390.
    • (2003) Prog. Neurobiol. , vol.69 , pp. 375-390
    • Jay, T.M.1
  • 89
    • 0037117736 scopus 로고    scopus 로고
    • Cell-type specific alterations of cortical interneurons in schizophrenic patients
    • Kalus P., Bondzio J., Federspiel A., Muller T. J., and, Zuschratter W., (2002) Cell-type specific alterations of cortical interneurons in schizophrenic patients. NeuroReport 13, 713-717.
    • (2002) NeuroReport , vol.13 , pp. 713-717
    • Kalus, P.1    Bondzio, J.2    Federspiel, A.3    Muller, T.J.4    Zuschratter, W.5
  • 90
    • 77956648156 scopus 로고    scopus 로고
    • N-methyl-d-aspartate (NMDA) receptor dysfunction or dysregulation: The final common pathway on the road to schizophrenia?
    • Kantrowitz J. T., and, Javitt D. C., (2010) N-methyl-d-aspartate (NMDA) receptor dysfunction or dysregulation: the final common pathway on the road to schizophrenia? Brain Res. Bull. 83, 108-121.
    • (2010) Brain Res. Bull. , vol.83 , pp. 108-121
    • Kantrowitz, J.T.1    Javitt, D.C.2
  • 91
    • 33744985583 scopus 로고    scopus 로고
    • DISC1 immunoreactivity at the light and ultrastructural level in the human neocortex
    • Kirkpatrick B., Xu L., Cascella N., Ozeki Y., Sawa A., and, Roberts R. C., (2006) DISC1 immunoreactivity at the light and ultrastructural level in the human neocortex. J. Comp. Neurol. 497, 436-450.
    • (2006) J. Comp. Neurol. , vol.497 , pp. 436-450
    • Kirkpatrick, B.1    Xu, L.2    Cascella, N.3    Ozeki, Y.4    Sawa, A.5    Roberts, R.C.6
  • 92
    • 84856225986 scopus 로고    scopus 로고
    • De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia
    • Kirov G., Pocklington A. J., Holmans P., et al,. (2012) De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia. Mol. Psychiatry 17, 142-153.
    • (2012) Mol. Psychiatry , vol.17 , pp. 142-153
    • Kirov, G.1    Pocklington, A.J.2    Holmans, P.3
  • 93
    • 62649174753 scopus 로고    scopus 로고
    • Oligomeric amyloid beta associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques
    • Koffie R. M., Meyer-Luehmann M., Hashimoto T., et al,. (2009) Oligomeric amyloid beta associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques. Proc. Natl Acad. Sci. USA 106, 4012-4017.
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 4012-4017
    • Koffie, R.M.1    Meyer-Luehmann, M.2    Hashimoto, T.3
  • 95
    • 19944397113 scopus 로고    scopus 로고
    • Ultrastructural alterations in hippocampal mossy fiber synapses in schizophrenia: A postmortem morphometric study
    • Kolomeets N. S., Orlovskaya D. D., Rachmanova V. I., and, Uranova N. A., (2005) Ultrastructural alterations in hippocampal mossy fiber synapses in schizophrenia: a postmortem morphometric study. Synapse 57, 47-55.
    • (2005) Synapse , vol.57 , pp. 47-55
    • Kolomeets, N.S.1    Orlovskaya, D.D.2    Rachmanova, V.I.3    Uranova, N.A.4
  • 96
    • 34250643126 scopus 로고    scopus 로고
    • Decreased numerical density of CA3 hippocampal mossy fiber synapses in schizophrenia
    • Kolomeets N. S., Orlovskaya D. D., and, Uranova N. A., (2007) Decreased numerical density of CA3 hippocampal mossy fiber synapses in schizophrenia. Synapse 61, 615-621.
    • (2007) Synapse , vol.61 , pp. 615-621
    • Kolomeets, N.S.1    Orlovskaya, D.D.2    Uranova, N.A.3
  • 98
    • 44349132300 scopus 로고    scopus 로고
    • A mutation in mouse Disc1 that models a schizophrenia risk allele leads to specific alterations in neuronal architecture and cognition
    • Kvajo M., McKellar H., Arguello P. A., Drew L. J., Moore H., MacDermott A. B., Karayiorgou M., and, Gogos J. A., (2008) A mutation in mouse Disc1 that models a schizophrenia risk allele leads to specific alterations in neuronal architecture and cognition. Proc. Natl Acad. Sci. USA 105, 7076-7081.
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 7076-7081
    • Kvajo, M.1    McKellar, H.2    Arguello, P.A.3    Drew, L.J.4    Moore, H.5    MacDermott, A.B.6    Karayiorgou, M.7    Gogos, J.A.8
  • 101
    • 0025805606 scopus 로고
    • An extended family of protein-tyrosine kinase genes differentially expressed in the vertebrate nervous system
    • Lai C., and, Lemke G., (1991) An extended family of protein-tyrosine kinase genes differentially expressed in the vertebrate nervous system. Neuron 6, 691-704.
    • (1991) Neuron , vol.6 , pp. 691-704
    • Lai, C.1    Lemke, G.2
  • 102
    • 33846619125 scopus 로고    scopus 로고
    • The role of neuronal complexes in human X-linked brain diseases
    • Laumonnier F., Cuthbert P. C., and, Grant S. G., (2007) The role of neuronal complexes in human X-linked brain diseases. Am. J. Hum. Genet. 80, 205-220.
    • (2007) Am. J. Hum. Genet. , vol.80 , pp. 205-220
    • Laumonnier, F.1    Cuthbert, P.C.2    Grant, S.G.3
  • 103
    • 2342508828 scopus 로고    scopus 로고
    • Reduced spinophilin but not microtubule-associated protein 2 expression in the hippocampal formation in schizophrenia and mood disorders: Molecular evidence for a pathology of dendritic spines
    • Law A. J., Weickert C. S., Hyde T. M., Kleinman J. E., and, Harrison P. J., (2004) Reduced spinophilin but not microtubule-associated protein 2 expression in the hippocampal formation in schizophrenia and mood disorders: molecular evidence for a pathology of dendritic spines. Am. J. Psychiatry 161, 1848-1855.
    • (2004) Am. J. Psychiatry , vol.161 , pp. 1848-1855
    • Law, A.J.1    Weickert, C.S.2    Hyde, T.M.3    Kleinman, J.E.4    Harrison, P.J.5
  • 104
    • 33846589304 scopus 로고    scopus 로고
    • Disease-associated intronic variants in the ErbB4 gene are related to altered ErbB4 splice-variant expression in the brain in schizophrenia
    • Law A. J., Kleinman J. E., Weinberger D. R., and, Weickert C. S., (2007) Disease-associated intronic variants in the ErbB4 gene are related to altered ErbB4 splice-variant expression in the brain in schizophrenia. Hum. Mol. Genet. 16, 129-141.
    • (2007) Hum. Mol. Genet. , vol.16 , pp. 129-141
    • Law, A.J.1    Kleinman, J.E.2    Weinberger, D.R.3    Weickert, C.S.4
  • 106
    • 36549081914 scopus 로고    scopus 로고
    • Neuroplasticity of neocortical circuits in schizophrenia
    • Lewis D. A., and, Gonzalez-Burgos G., (2008) Neuroplasticity of neocortical circuits in schizophrenia. Neuropsychopharmacology 33, 141-165.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 141-165
    • Lewis, D.A.1    Gonzalez-Burgos, G.2
  • 107
    • 0036308284 scopus 로고    scopus 로고
    • Schizophrenia as a disorder of neurodevelopment
    • Lewis D. A., and, Levitt P., (2002) Schizophrenia as a disorder of neurodevelopment. Annu. Rev. Neurosci. 25, 409-432.
    • (2002) Annu. Rev. Neurosci. , vol.25 , pp. 409-432
    • Lewis, D.A.1    Levitt, P.2
  • 108
    • 16344372645 scopus 로고    scopus 로고
    • Cortical inhibitory neurons and schizophrenia
    • Lewis D. A., Hashimoto T., and, Volk D. W., (2005) Cortical inhibitory neurons and schizophrenia. Nat. Rev. Neurosci. 6, 312-324.
    • (2005) Nat. Rev. Neurosci. , vol.6 , pp. 312-324
    • Lewis, D.A.1    Hashimoto, T.2    Volk, D.W.3
  • 109
    • 34248531426 scopus 로고    scopus 로고
    • The neuregulin-1 receptor erbB4 controls glutamatergic synapse maturation and plasticity
    • Li B., Woo R. S., Mei L., and, Malinow R., (2007) The neuregulin-1 receptor erbB4 controls glutamatergic synapse maturation and plasticity. Neuron 54, 583-597.
    • (2007) Neuron , vol.54 , pp. 583-597
    • Li, B.1    Woo, R.S.2    Mei, L.3    Malinow, R.4
  • 110
    • 84856293318 scopus 로고    scopus 로고
    • Neuregulin 1 regulates excitability of fast-spiking neurons through Kv1.1 and acts in epilepsy
    • Li K. X., Lu Y. M., Xu Z. H., et al,. (2012) Neuregulin 1 regulates excitability of fast-spiking neurons through Kv1.1 and acts in epilepsy. Nat. Neurosci. 15, 267-273.
    • (2012) Nat. Neurosci. , vol.15 , pp. 267-273
    • Li, K.X.1    Lu, Y.M.2    Xu, Z.H.3
  • 111
    • 33645828206 scopus 로고    scopus 로고
    • Expression of DISC1 binding partners is reduced in schizophrenia and associated with DISC1 SNPs
    • Lipska B. K., Peters T., Hyde T. M., et al,. (2006) Expression of DISC1 binding partners is reduced in schizophrenia and associated with DISC1 SNPs. Hum. Mol. Genet. 15, 1245-1258.
    • (2006) Hum. Mol. Genet. , vol.15 , pp. 1245-1258
    • Lipska, B.K.1    Peters, T.2    Hyde, T.M.3
  • 112
    • 19544370227 scopus 로고    scopus 로고
    • The hippocampal-VTA loop: Controlling the entry of information into long-term memory
    • Lisman J. E., and, Grace A. A., (2005) The hippocampal-VTA loop: controlling the entry of information into long-term memory. Neuron 46, 703-713.
    • (2005) Neuron , vol.46 , pp. 703-713
    • Lisman, J.E.1    Grace, A.A.2
  • 113
    • 42749095376 scopus 로고    scopus 로고
    • Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia
    • Lisman J. E., Coyle J. T., Green R. W., Javitt D. C., Benes F. M., Heckers S., and, Grace A. A., (2008) Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia. Trends Neurosci. 31, 234-242.
    • (2008) Trends Neurosci. , vol.31 , pp. 234-242
    • Lisman, J.E.1    Coyle, J.T.2    Green, R.W.3    Javitt, D.C.4    Benes, F.M.5    Heckers, S.6    Grace, A.A.7
  • 114
  • 117
    • 0026495288 scopus 로고
    • Na+ conductance and the threshold for repetitive neuronal firing
    • Matzner O., and, Devor M., (1992) Na+ conductance and the threshold for repetitive neuronal firing. Brain Res. 597, 92-98.
    • (1992) Brain Res. , vol.597 , pp. 92-98
    • Matzner, O.1    Devor, M.2
  • 119
    • 43949084738 scopus 로고    scopus 로고
    • Neuregulin 1 in neural development, synaptic plasticity and schizophrenia
    • Mei L., and, Xiong W. C., (2008) Neuregulin 1 in neural development, synaptic plasticity and schizophrenia. Nat. Rev. Neurosci. 9, 437-452.
    • (2008) Nat. Rev. Neurosci. , vol.9 , pp. 437-452
    • Mei, L.1    Xiong, W.C.2
  • 120
    • 84866606706 scopus 로고    scopus 로고
    • SCN1A affects brain structure and the neural activity of the aging brain
    • Meier S., Demirakca T., Brusniak W., et al,. (2012) SCN1A affects brain structure and the neural activity of the aging brain. Biol. Psychiatry 72, 677-683.
    • (2012) Biol. Psychiatry , vol.72 , pp. 677-683
    • Meier, S.1    Demirakca, T.2    Brusniak, W.3
  • 121
    • 0028783527 scopus 로고
    • Abnormal brain glucose metabolism in the delusional misidentification syndromes: A positron emission tomography study in Alzheimer disease
    • Mentis M. J., Weinstein E. A., Horwitz B., McIntosh A. R., Pietrini P., Alexander G. E., Furey M., and, Murphy D. G., (1995) Abnormal brain glucose metabolism in the delusional misidentification syndromes: a positron emission tomography study in Alzheimer disease. Biol. Psychiatry 38, 438-449.
    • (1995) Biol. Psychiatry , vol.38 , pp. 438-449
    • Mentis, M.J.1    Weinstein, E.A.2    Horwitz, B.3    McIntosh, A.R.4    Pietrini, P.5    Alexander, G.E.6    Furey, M.7    Murphy, D.G.8
  • 122
    • 69249248178 scopus 로고    scopus 로고
    • Neural basis of psychosis-related behaviour in the infection model of schizophrenia
    • Meyer U., and, Feldon J., (2009) Neural basis of psychosis-related behaviour in the infection model of schizophrenia. Behav. Brain Res. 204, 322-334.
    • (2009) Behav. Brain Res. , vol.204 , pp. 322-334
    • Meyer, U.1    Feldon, J.2
  • 123
    • 77956594956 scopus 로고    scopus 로고
    • Kinetic properties and functional dynamics of sodium channels during repetitive spiking in a slow pacemaker neuron
    • Milescu L. S., Yamanishi T., Ptak K., and, Smith J. C., (2010) Kinetic properties and functional dynamics of sodium channels during repetitive spiking in a slow pacemaker neuron. J. Neurosci. 30, 12113-12127.
    • (2010) J. Neurosci. , vol.30 , pp. 12113-12127
    • Milescu, L.S.1    Yamanishi, T.2    Ptak, K.3    Smith, J.C.4
  • 124
    • 0242437914 scopus 로고    scopus 로고
    • Yeast two-hybrid screens implicate DISC1 in brain development and function
    • Millar J. K., Christie S., and, Porteous D. J., (2003) Yeast two-hybrid screens implicate DISC1 in brain development and function. Biochem. Biophys. Res. Commun. 311, 1019-1025.
    • (2003) Biochem. Biophys. Res. Commun. , vol.311 , pp. 1019-1025
    • Millar, J.K.1    Christie, S.2    Porteous, D.J.3
  • 125
    • 36749040875 scopus 로고    scopus 로고
    • Contribution of SHANK3 mutations to autism spectrum disorder
    • Moessner R., Marshall C. R., Sutcliffe J. S., et al,. (2007) Contribution of SHANK3 mutations to autism spectrum disorder. Am. J. Hum. Genet. 81, 1289-1297.
    • (2007) Am. J. Hum. Genet. , vol.81 , pp. 1289-1297
    • Moessner, R.1    Marshall, C.R.2    Sutcliffe, J.S.3
  • 126
    • 0033588176 scopus 로고    scopus 로고
    • Mice with reduced NMDA receptor expression display behaviors related to schizophrenia
    • Mohn A. R., Gainetdinov R. R., Caron M. G., and, Koller B. H., (1999) Mice with reduced NMDA receptor expression display behaviors related to schizophrenia. Cell 98, 427-436.
    • (1999) Cell , vol.98 , pp. 427-436
    • Mohn, A.R.1    Gainetdinov, R.R.2    Caron, M.G.3    Koller, B.H.4
  • 129
    • 33745712841 scopus 로고    scopus 로고
    • Association of the NRG1 gene and schizophrenia: A meta-analysis
    • Munafo M. R., Thiselton D. L., Clark T. G., and, Flint J., (2006) Association of the NRG1 gene and schizophrenia: a meta-analysis. Mol. Psychiatry 11, 539-546.
    • (2006) Mol. Psychiatry , vol.11 , pp. 539-546
    • Munafo, M.R.1    Thiselton, D.L.2    Clark, T.G.3    Flint, J.4
  • 130
  • 132
    • 84866759278 scopus 로고    scopus 로고
    • Beta-Amyloid 42/40 ratio and kalirin expression in Alzheimer disease with psychosis
    • Murray P. S., Kirkwood C. M., Gray M. C., et al,. (2012) beta-Amyloid 42/40 ratio and kalirin expression in Alzheimer disease with psychosis. Neurobiol. Aging 33, 2807-2816.
    • (2012) Neurobiol. Aging , vol.33 , pp. 2807-2816
    • Murray, P.S.1    Kirkwood, C.M.2    Gray, M.C.3
  • 134
    • 37449016136 scopus 로고    scopus 로고
    • Rho-linked genes and neurological disorders
    • Nadif Kasri N., and, Van Aelst L., (2008) Rho-linked genes and neurological disorders. Pflugers Arch. 455, 787-797.
    • (2008) Pflugers Arch. , vol.455 , pp. 787-797
    • Nadif Kasri, N.1    Van Aelst, L.2
  • 135
    • 0038117796 scopus 로고    scopus 로고
    • Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline
    • Naslund J., Haroutunian V., Mohs R., Davis K. L., Davies P., Greengard P., and, Buxbaum J. D., (2000) Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline. JAMA 283, 1571-1577.
    • (2000) JAMA , vol.283 , pp. 1571-1577
    • Naslund, J.1    Haroutunian, V.2    Mohs, R.3    Davis, K.L.4    Davies, P.5    Greengard, P.6    Buxbaum, J.D.7
  • 136
    • 77953053247 scopus 로고    scopus 로고
    • Selective populations of hippocampal interneurons express ErbB4 and their number and distribution is altered in ErbB4 knockout mice
    • Neddens J., and, Buonanno A., (2009) Selective populations of hippocampal interneurons express ErbB4 and their number and distribution is altered in ErbB4 knockout mice. Hippocampus 20, 724-744.
    • (2009) Hippocampus , vol.20 , pp. 724-744
    • Neddens, J.1    Buonanno, A.2
  • 137
    • 80555145249 scopus 로고    scopus 로고
    • Expression of the neuregulin receptor ErbB4 in the brain of the rhesus monkey (Macaca mulatta)
    • Neddens J., and, Buonanno A., (2011) Expression of the neuregulin receptor ErbB4 in the brain of the rhesus monkey (Macaca mulatta). PLoS ONE 6, e27337.
    • (2011) PLoS ONE , vol.6
    • Neddens, J.1    Buonanno, A.2
  • 138
    • 80052863881 scopus 로고    scopus 로고
    • Conserved interneuron-specific ErbB4 expression in frontal cortex of rodents, monkeys, and humans: Implications for schizophrenia
    • Neddens J., Fish K. N., Tricoire L., Vullhorst D., Shamir A., Chung W., Lewis D. A., McBain C. J., and, Buonanno A., (2011) Conserved interneuron-specific ErbB4 expression in frontal cortex of rodents, monkeys, and humans: implications for schizophrenia. Biol. Psychiatry 70, 636-645.
    • (2011) Biol. Psychiatry , vol.70 , pp. 636-645
    • Neddens, J.1    Fish, K.N.2    Tricoire, L.3    Vullhorst, D.4    Shamir, A.5    Chung, W.6    Lewis, D.A.7    McBain, C.J.8    Buonanno, A.9
  • 139
    • 77957719415 scopus 로고    scopus 로고
    • Biological validation of increased schizophrenia risk with NRG1, ERBB4, and AKT1 epistasis via functional neuroimaging in healthy controls
    • Nicodemus K. K., Law A. J., Radulescu E., et al,. (2010) Biological validation of increased schizophrenia risk with NRG1, ERBB4, and AKT1 epistasis via functional neuroimaging in healthy controls. Arch. Gen. Psychiatry 67, 991-1001.
    • (2010) Arch. Gen. Psychiatry , vol.67 , pp. 991-1001
    • Nicodemus, K.K.1    Law, A.J.2    Radulescu, E.3
  • 140
    • 77955170379 scopus 로고    scopus 로고
    • Decreased GABA(B) receptors in the cingulate cortex and fusiform gyrus in autism
    • Oblak A. L., Gibbs T. T., and, Blatt G. J., (2010) Decreased GABA(B) receptors in the cingulate cortex and fusiform gyrus in autism. J. Neurochem. 114, 1414-1423.
    • (2010) J. Neurochem. , vol.114 , pp. 1414-1423
    • Oblak, A.L.1    Gibbs, T.T.2    Blatt, G.J.3
  • 141
    • 42649096881 scopus 로고    scopus 로고
    • Autism genetics: Strategies, challenges, and opportunities
    • O'Roak B. J., and, State M. W., (2008) Autism genetics: strategies, challenges, and opportunities. Autism. Res. 1, 4-17.
    • (2008) Autism. Res. , vol.1 , pp. 4-17
    • O'Roak, B.J.1    State, M.W.2
  • 143
    • 74849134916 scopus 로고    scopus 로고
    • A postsynaptic signaling pathway that may account for the cognitive defect due to IL1RAPL1 mutation
    • Pavlowsky A., Gianfelice A., Pallotto M., et al,. (2010) A postsynaptic signaling pathway that may account for the cognitive defect due to IL1RAPL1 mutation. Curr. Biol. 20, 103-115.
    • (2010) Curr. Biol. , vol.20 , pp. 103-115
    • Pavlowsky, A.1    Gianfelice, A.2    Pallotto, M.3
  • 145
    • 47649093892 scopus 로고    scopus 로고
    • Dendritic spine dynamics-a key role for kalirin-7
    • Penzes P., and, Jones K. A., (2008) Dendritic spine dynamics-a key role for kalirin-7. Trends Neurosci. 31, 419-427.
    • (2008) Trends Neurosci. , vol.31 , pp. 419-427
    • Penzes, P.1    Jones, K.A.2
  • 146
    • 49849092490 scopus 로고    scopus 로고
    • Convergent CaMK and RacGEF signals control dendritic structure and function
    • Penzes P., Cahill M. E., Jones K. A., and, Srivastava D. P., (2008) Convergent CaMK and RacGEF signals control dendritic structure and function. Trends Cell Biol. 18, 405-413.
    • (2008) Trends Cell Biol. , vol.18 , pp. 405-413
    • Penzes, P.1    Cahill, M.E.2    Jones, K.A.3    Srivastava, D.P.4
  • 148
    • 77954657070 scopus 로고    scopus 로고
    • Functional impact of global rare copy number variation in autism spectrum disorders
    • Pinto D., Pagnamenta A. T., Klei L., et al,. (2010) Functional impact of global rare copy number variation in autism spectrum disorders. Nature 466, 368-372.
    • (2010) Nature , vol.466 , pp. 368-372
    • Pinto, D.1    Pagnamenta, A.T.2    Klei, L.3
  • 149
    • 57049170205 scopus 로고    scopus 로고
    • Mutations in the calcium-related gene IL1RAPL1 are associated with autism
    • Piton A., Michaud J. L., Peng H., et al,. (2008) Mutations in the calcium-related gene IL1RAPL1 are associated with autism. Hum. Mol. Genet. 17, 3965-3974.
    • (2008) Hum. Mol. Genet. , vol.17 , pp. 3965-3974
    • Piton, A.1    Michaud, J.L.2    Peng, H.3
  • 150
    • 83555168191 scopus 로고    scopus 로고
    • Disentangling the myriad genomics of complex disorders, specifically focusing on autism, epilepsy, and schizophrenia
    • Poot M., van der Smagt J. J., Brilstra E. H., and, Bourgeron T., (2011) Disentangling the myriad genomics of complex disorders, specifically focusing on autism, epilepsy, and schizophrenia. Cytogenet. Genome Res. 135, 228-240.
    • (2011) Cytogenet. Genome Res. , vol.135 , pp. 228-240
    • Poot, M.1    Van Der Smagt, J.J.2    Brilstra, E.H.3    Bourgeron, T.4
  • 151
    • 84856863574 scopus 로고    scopus 로고
    • Rapid reversal of impaired inhibitory and excitatory transmission but not spine dysgenesis in a mouse model of mental retardation
    • Powell A. D., Gill K. K., Saintot P. P., Jiruska P., Chelly J., Billuart P., and, Jefferys J. G., (2012) Rapid reversal of impaired inhibitory and excitatory transmission but not spine dysgenesis in a mouse model of mental retardation. J. Physiol. 590, 763-776.
    • (2012) J. Physiol. , vol.590 , pp. 763-776
    • Powell, A.D.1    Gill, K.K.2    Saintot, P.P.3    Jiruska, P.4    Chelly, J.5    Billuart, P.6    Jefferys, J.G.7
  • 152
    • 0022450104 scopus 로고
    • Concurrent overproduction of synapses in diverse regions of the primate cerebral cortex
    • Rakic P., Bourgeois J. P., Eckenhoff M. F., Zecevic N., and, Goldman-Rakic P. S., (1986) Concurrent overproduction of synapses in diverse regions of the primate cerebral cortex. Science 232, 232-235.
    • (1986) Science , vol.232 , pp. 232-235
    • Rakic, P.1    Bourgeois, J.P.2    Eckenhoff, M.F.3    Zecevic, N.4    Goldman-Rakic, P.S.5
  • 153
    • 18444385647 scopus 로고    scopus 로고
    • (2005) the neurodevelopmental model of schizophrenia: Update
    • Rapoport J. L., Addington A. M., Frangou S., and, Psych M. R., (2005) (2005) The neurodevelopmental model of schizophrenia: update. Mol. Psychiatry 10, 434-449.
    • (2005) Mol. Psychiatry , vol.10 , pp. 434-449
    • Rapoport, J.L.1    Addington, A.M.2    Frangou, S.3    Psych, M.R.4
  • 154
    • 33749465589 scopus 로고    scopus 로고
    • Diagnostic yield of various genetic approaches in patients with unexplained developmental delay or mental retardation
    • Rauch A., Hoyer J., Guth S., et al,. (2006) Diagnostic yield of various genetic approaches in patients with unexplained developmental delay or mental retardation. Am. J. Med. Genet. A 140, 2063-2074.
    • (2006) Am. J. Med. Genet. A , vol.140 , pp. 2063-2074
    • Rauch, A.1    Hoyer, J.2    Guth, S.3
  • 155
    • 27744593088 scopus 로고    scopus 로고
    • Epidemiology of and risk factors for psychosis of Alzheimer's disease: A review of 55 studies published from 1990 to 2003
    • Ropacki S. A., and, Jeste D. V., (2005) Epidemiology of and risk factors for psychosis of Alzheimer's disease: a review of 55 studies published from 1990 to 2003. Am. J. Psychiatry 162, 2022-2030.
    • (2005) Am. J. Psychiatry , vol.162 , pp. 2022-2030
    • Ropacki, S.A.1    Jeste, D.V.2
  • 156
    • 10644243538 scopus 로고    scopus 로고
    • X-linked mental retardation
    • Ropers H. H., and, Hamel B. C., (2005) X-linked mental retardation. Nat. Rev. Genet. 6, 46-57.
    • (2005) Nat. Rev. Genet. , vol.6 , pp. 46-57
    • Ropers, H.H.1    Hamel, B.C.2
  • 157
    • 79952115634 scopus 로고    scopus 로고
    • The role of the classical complement cascade in synapse loss during development and glaucoma
    • Rosen A. M., and, Stevens B., (2010) The role of the classical complement cascade in synapse loss during development and glaucoma. Adv. Exp. Med. Biol. 703, 75-93.
    • (2010) Adv. Exp. Med. Biol. , vol.703 , pp. 75-93
    • Rosen, A.M.1    Stevens, B.2
  • 158
    • 84860739976 scopus 로고    scopus 로고
    • SHANK1 Deletions in Males with Autism Spectrum Disorder
    • Sato D., Lionel A. C., Leblond C. S., et al,. (2012) SHANK1 Deletions in Males with Autism Spectrum Disorder. Am. J. Hum. Genet. 90, 879-887.
    • (2012) Am. J. Hum. Genet. , vol.90 , pp. 879-887
    • Sato, D.1    Lionel, A.C.2    Leblond, C.S.3
  • 159
    • 0345276568 scopus 로고    scopus 로고
    • Synaptic pathology in Alzheimer's disease: A review of ultrastructural studies
    • Scheff S. W., and, Price D. A., (2003) Synaptic pathology in Alzheimer's disease: a review of ultrastructural studies. Neurobiol. Aging 24, 1029-1046.
    • (2003) Neurobiol. Aging , vol.24 , pp. 1029-1046
    • Scheff, S.W.1    Price, D.A.2
  • 160
    • 84862274500 scopus 로고    scopus 로고
    • Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2
    • Schmeisser M. J., Ey E., Wegener S., et al,. (2012) Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2. Nature 486, 256-260.
    • (2012) Nature , vol.486 , pp. 256-260
    • Schmeisser, M.J.1    Ey, E.2    Wegener, S.3
  • 161
    • 67649832375 scopus 로고    scopus 로고
    • The DISC locus and schizophrenia: Evidence from an association study in a central European sample and from a meta-analysis across different European populations
    • Schumacher J., Laje G., Abou Jamra R., et al,. (2009) The DISC locus and schizophrenia: evidence from an association study in a central European sample and from a meta-analysis across different European populations. Hum. Mol. Genet. 18, 2719-2727.
    • (2009) Hum. Mol. Genet. , vol.18 , pp. 2719-2727
    • Schumacher, J.1    Laje, G.2    Abou Jamra, R.3
  • 162
    • 65649083782 scopus 로고    scopus 로고
    • Glutamate and dopamine components in schizophrenia
    • Seeman P., (2009) Glutamate and dopamine components in schizophrenia. J. Psychiatry Neurosci. 34, 143-149.
    • (2009) J. Psychiatry Neurosci. , vol.34 , pp. 143-149
    • Seeman, P.1
  • 163
    • 0032967531 scopus 로고    scopus 로고
    • The reduced neuropil hypothesis: A circuit based model of schizophrenia
    • Selemon L. D., and, Goldman-Rakic P. S., (1999) The reduced neuropil hypothesis: a circuit based model of schizophrenia. Biol. Psychiatry 45, 17-25.
    • (1999) Biol. Psychiatry , vol.45 , pp. 17-25
    • Selemon, L.D.1    Goldman-Rakic, P.S.2
  • 164
    • 0037174618 scopus 로고    scopus 로고
    • Alzheimer's disease is a synaptic failure
    • Selkoe D. J., (2002) Alzheimer's disease is a synaptic failure. Science 298, 789-791.
    • (2002) Science , vol.298 , pp. 789-791
    • Selkoe, D.J.1
  • 165
    • 44549087765 scopus 로고    scopus 로고
    • Soluble oligomers of the amyloid beta-protein impair synaptic plasticity and behavior
    • Selkoe D. J., (2008) Soluble oligomers of the amyloid beta-protein impair synaptic plasticity and behavior. Behav. Brain Res. 192, 106-113.
    • (2008) Behav. Brain Res. , vol.192 , pp. 106-113
    • Selkoe, D.J.1
  • 166
    • 84857622035 scopus 로고    scopus 로고
    • The importance of the NRG-1/ErbB4 pathway for synaptic plasticity and behaviors associated with psychiatric disorders
    • Shamir A., Kwon O. B., Karavanova I., Vullhorst D., Leiva-Salcedo E., Janssen M. J., and, Buonanno A., (2012) The importance of the NRG-1/ErbB4 pathway for synaptic plasticity and behaviors associated with psychiatric disorders. J. Neurosci. 32, 2988-2997.
    • (2012) J. Neurosci. , vol.32 , pp. 2988-2997
    • Shamir, A.1    Kwon, O.B.2    Karavanova, I.3    Vullhorst, D.4    Leiva-Salcedo, E.5    Janssen, M.J.6    Buonanno, A.7
  • 167
    • 79551510136 scopus 로고    scopus 로고
    • Tau protein is required for amyloid {beta}-induced impairment of hippocampal long-term potentiation
    • Shipton O. A., Leitz J. R., Dworzak J., et al,. (2011) Tau protein is required for amyloid {beta}-induced impairment of hippocampal long-term potentiation. J. Neurosci. 31, 1688-1692.
    • (2011) J. Neurosci. , vol.31 , pp. 1688-1692
    • Shipton, O.A.1    Leitz, J.R.2    Dworzak, J.3
  • 168
    • 32244444322 scopus 로고    scopus 로고
    • The involvement of ErbB4 with schizophrenia: Association and expression studies. American journal of medical genetics. Part B, Neuropsychiatric genetics: The official publication of the International Society of
    • Silberberg G., Darvasi A., Pinkas-Kramarski R., and, Navon R., (2006) The involvement of ErbB4 with schizophrenia: association and expression studies. American journal of medical genetics. Part B, Neuropsychiatric genetics: the official publication of the International Society of. Psychiatr. Genet. 141B, 142-148.
    • (2006) Psychiatr. Genet. , vol.141 B , pp. 142-148
    • Silberberg, G.1    Darvasi, A.2    Pinkas-Kramarski, R.3    Navon, R.4
  • 169
    • 77956650298 scopus 로고    scopus 로고
    • The functional consequences of cortical circuit abnormalities on gamma oscillations in schizophrenia: Insights from computational modeling
    • Spencer K. M., (2009) The functional consequences of cortical circuit abnormalities on gamma oscillations in schizophrenia: insights from computational modeling. Front. Hum. Neurosci. 3, 33.
    • (2009) Front. Hum. Neurosci. , vol.3 , pp. 33
    • Spencer, K.M.1
  • 172
    • 77954891060 scopus 로고    scopus 로고
    • Synapse pathology in psychiatric and neurologic disease
    • van Spronsen M., and, Hoogenraad C. C., (2010) Synapse pathology in psychiatric and neurologic disease. Curr. Neurol. Neurosci. Rep. 10, 207-214.
    • (2010) Curr. Neurol. Neurosci. Rep. , vol.10 , pp. 207-214
    • Van Spronsen, M.1    Hoogenraad, C.C.2
  • 173
    • 43949124669 scopus 로고    scopus 로고
    • Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model
    • Stark K. L., Xu B., Bagchi A., et al,. (2008) Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model. Nat. Genet. 40, 751-760.
    • (2008) Nat. Genet. , vol.40 , pp. 751-760
    • Stark, K.L.1    Xu, B.2    Bagchi, A.3
  • 175
    • 33744901419 scopus 로고    scopus 로고
    • Brain volume in first-episode schizophrenia: Systematic review and meta-analysis of magnetic resonance imaging studies
    • Steen R. G., Mull C., McClure R., Hamer R. M., and, Lieberman J. A., (2006) Brain volume in first-episode schizophrenia: systematic review and meta-analysis of magnetic resonance imaging studies. Br. J. Psychiatry 188, 510-518.
    • (2006) Br. J. Psychiatry , vol.188 , pp. 510-518
    • Steen, R.G.1    Mull, C.2    McClure, R.3    Hamer, R.M.4    Lieberman, J.A.5
  • 178
    • 0032849480 scopus 로고    scopus 로고
    • Differential expression of ErbB3 and ErbB4 neuregulin receptors in dopamine neurons and forebrain areas of the adult rat
    • Steiner H., Blum M., Kitai S. T., and, Fedi P., (1999) Differential expression of ErbB3 and ErbB4 neuregulin receptors in dopamine neurons and forebrain areas of the adult rat. Exp. Neurol. 159, 494-503.
    • (1999) Exp. Neurol. , vol.159 , pp. 494-503
    • Steiner, H.1    Blum, M.2    Kitai, S.T.3    Fedi, P.4
  • 180
    • 0037177079 scopus 로고    scopus 로고
    • Increased familial risk of the psychotic phenotype of Alzheimer disease
    • Sweet R. A., Nimgaonkar V. L., Devlin B., Lopez O. L., and, DeKosky S. T., (2002a) Increased familial risk of the psychotic phenotype of Alzheimer disease. Neurology 58, 907-911.
    • (2002) Neurology , vol.58 , pp. 907-911
    • Sweet, R.A.1    Nimgaonkar, V.L.2    Devlin, B.3    Lopez, O.L.4    Dekosky, S.T.5
  • 182
  • 183
    • 77950799868 scopus 로고    scopus 로고
    • Assessment and familial aggregation of psychosis in Alzheimer's disease from the National Institute on Aging Late Onset Alzheimer's Disease Family Study
    • Sweet R. A., Bennett D. A., Graff-Radford N. R., and, Mayeux R., (2010) Assessment and familial aggregation of psychosis in Alzheimer's disease from the National Institute on Aging Late Onset Alzheimer's Disease Family Study. Brain 133, 1155-1162.
    • (2010) Brain , vol.133 , pp. 1155-1162
    • Sweet, R.A.1    Bennett, D.A.2    Graff-Radford, N.R.3    Mayeux, R.4
  • 185
    • 32344435520 scopus 로고    scopus 로고
    • Molecular mechanisms of dendritic spine morphogenesis
    • Tada T., and, Sheng M., (2006) Molecular mechanisms of dendritic spine morphogenesis. Curr. Opin. Neurobiol. 16, 95-101.
    • (2006) Curr. Opin. Neurobiol. , vol.16 , pp. 95-101
    • Tada, T.1    Sheng, M.2
  • 186
    • 77958550106 scopus 로고    scopus 로고
    • Molecular cloning and characterization of the human ErbB4 gene: Identification of novel splice isoforms in the developing and adult brain
    • Tan W., Dean M., and, Law A. J., (2010) Molecular cloning and characterization of the human ErbB4 gene: identification of novel splice isoforms in the developing and adult brain. PLoS ONE 5, e12924.
    • (2010) PLoS ONE , vol.5
    • Tan, W.1    Dean, M.2    Law, A.J.3
  • 187
    • 0025987048 scopus 로고
    • Physical basis of cognitive alterations in Alzheimer's disease: Synapse loss is the major correlate of cognitive impairment
    • Terry R. D., Masliah E., Salmon D. P., Butters N., DeTeresa R., Hill R., Hansen L. A., and, Katzman R., (1991) Physical basis of cognitive alterations in Alzheimer's disease: Synapse loss is the major correlate of cognitive impairment. Ann. Neurol. 30, 572-580.
    • (1991) Ann. Neurol. , vol.30 , pp. 572-580
    • Terry, R.D.1    Masliah, E.2    Salmon, D.P.3    Butters, N.4    Deteresa, R.5    Hill, R.6    Hansen, L.A.7    Katzman, R.8
  • 189
    • 34547687648 scopus 로고    scopus 로고
    • Cell type-specific tuning of hippocampal interneuron firing during gamma oscillations in vivo
    • Tukker J. J., Fuentealba P., Hartwich K., Somogyi P., and, Klausberger T., (2007) Cell type-specific tuning of hippocampal interneuron firing during gamma oscillations in vivo. J. Neurosci. 27, 8184-8189.
    • (2007) J. Neurosci. , vol.27 , pp. 8184-8189
    • Tukker, J.J.1    Fuentealba, P.2    Hartwich, K.3    Somogyi, P.4    Klausberger, T.5
  • 190
    • 80053293745 scopus 로고    scopus 로고
    • A circadian clock in hippocampus is regulated by interaction between oligophrenin-1 and Rev-erbα
    • Valnegri P., Khelfaoui M., Dorseuil O., et al,. (2011a) A circadian clock in hippocampus is regulated by interaction between oligophrenin-1 and Rev-erbα. Nat. Neurosci. 14, 1293-1301.
    • (2011) Nat. Neurosci. , vol.14 , pp. 1293-1301
    • Valnegri, P.1    Khelfaoui, M.2    Dorseuil, O.3
  • 191
    • 81855173451 scopus 로고    scopus 로고
    • The X-linked intellectual disability protein IL1RAPL1 regulates excitatory synapse formation by binding PTPδ and RhoGAP2
    • Valnegri P., Montrasio C., Brambilla D., Ko J. W., Passafaro M., and, Sala C., (2011b) The X-linked intellectual disability protein IL1RAPL1 regulates excitatory synapse formation by binding PTPδ and RhoGAP2. Hum. Mol. Genet. 20, 4797-4809.
    • (2011) Hum. Mol. Genet. , vol.20 , pp. 4797-4809
    • Valnegri, P.1    Montrasio, C.2    Brambilla, D.3    Ko, J.W.4    Passafaro, M.5    Sala, C.6
  • 192
    • 80053423590 scopus 로고    scopus 로고
    • Importance of shank3 in regulating metabotropic glutamate receptor 5 (mGluR5) expression and signaling at synapses
    • Verpelli C., Dvoretskova E., Vicidomini C., et al,. (2011) Importance of shank3 in regulating metabotropic glutamate receptor 5 (mGluR5) expression and signaling at synapses. J. Biol. Chem. 286, 34839-34850.
    • (2011) J. Biol. Chem. , vol.286 , pp. 34839-34850
    • Verpelli, C.1    Dvoretskova, E.2    Vicidomini, C.3
  • 194
    • 34248190279 scopus 로고    scopus 로고
    • A beta oligomers - A decade of discovery
    • Walsh D. M., and, Selkoe D. J., (2007) A beta oligomers-a decade of discovery. J. Neurochem. 101, 1172-1184.
    • (2007) J. Neurochem. , vol.101 , pp. 1172-1184
    • Walsh, D.M.1    Selkoe, D.J.2
  • 196
    • 79960111638 scopus 로고    scopus 로고
    • Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3
    • Wang X., McCoy P. A., Rodriguiz R. M., et al,. (2011) Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3. Hum. Mol. Genet. 20, 3093-3108.
    • (2011) Hum. Mol. Genet. , vol.20 , pp. 3093-3108
    • Wang, X.1    McCoy, P.A.2    Rodriguiz, R.M.3
  • 197
    • 84859791378 scopus 로고    scopus 로고
    • Schizophrenia-associated HapICE haplotype is associated with increased NRG1 type III expression and high nucleotide diversity
    • Weickert C. S., Tiwari Y., Schofield P. R., Mowry B. J., and, Fullerton J. M., (2012) Schizophrenia-associated HapICE haplotype is associated with increased NRG1 type III expression and high nucleotide diversity. Transl. Psychiatry 2, e104.
    • (2012) Transl. Psychiatry , vol.2
    • Weickert, C.S.1    Tiwari, Y.2    Schofield, P.R.3    Mowry, B.J.4    Fullerton, J.M.5
  • 198
    • 84879356091 scopus 로고    scopus 로고
    • KCNIP4 as a candidate gene for personality disorders and adult ADHD
    • Weissflog L., Scholz C. J., Jacob C. P., et al,. (2012) KCNIP4 as a candidate gene for personality disorders and adult ADHD. Eur. Neuropsychopharmacol. S0924-977X, 00214-3.
    • (2012) Eur. Neuropsychopharmacol. , pp. 214-213
    • Weissflog, L.1    Scholz, C.J.2    Jacob, C.P.3
  • 199
    • 75749110218 scopus 로고    scopus 로고
    • Neuregulin 1 regulates pyramidal neuron activity via ErbB4 in parvalbumin-positive interneurons
    • Wen L., Lu Y. S., Zhu X. H., et al,. (2010) Neuregulin 1 regulates pyramidal neuron activity via ErbB4 in parvalbumin-positive interneurons. Proc. Natl Acad. Sci. USA 107, 1211-1216.
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 1211-1216
    • Wen, L.1    Lu, Y.S.2    Zhu, X.H.3
  • 200
    • 0042828948 scopus 로고    scopus 로고
    • Molecular characterisation of the 22q13 deletion syndrome supports the role of haploinsufficiency of SHANK3/PROSAP2 in the major neurological symptoms
    • Wilson H. L., Wong A. C., Shaw S. R., Tse W. Y., Stapleton G. A., Phelan M. C., Hu S., Marshall J., and, McDermid H. E., (2003) Molecular characterisation of the 22q13 deletion syndrome supports the role of haploinsufficiency of SHANK3/PROSAP2 in the major neurological symptoms. J. Med. Genet. 40, 575-584.
    • (2003) J. Med. Genet. , vol.40 , pp. 575-584
    • Wilson, H.L.1    Wong, A.C.2    Shaw, S.R.3    Tse, W.Y.4    Stapleton, G.A.5    Phelan, M.C.6    Hu, S.7    Marshall, J.8    McDermid, H.E.9
  • 201
    • 38849108713 scopus 로고    scopus 로고
    • Cortical gamma generators suggest abnormal auditory circuitry in early-onset psychosis
    • Wilson T. W., Hernandez O. O., Asherin R. M., Teale P. D., Reite M. L., and, Rojas D. C., (2008) Cortical gamma generators suggest abnormal auditory circuitry in early-onset psychosis. Cereb. Cortex 18, 371-378.
    • (2008) Cereb. Cortex , vol.18 , pp. 371-378
    • Wilson, T.W.1    Hernandez, O.O.2    Asherin, R.M.3    Teale, P.D.4    Reite, M.L.5    Rojas, D.C.6
  • 202
    • 5044225291 scopus 로고    scopus 로고
    • Genes, dopamine and cortical signal-to-noise ratio in schizophrenia
    • Winterer G., and, Weinberger D. R., (2004) Genes, dopamine and cortical signal-to-noise ratio in schizophrenia. Trends Neurosci. 27, 683-690.
    • (2004) Trends Neurosci. , vol.27 , pp. 683-690
    • Winterer, G.1    Weinberger, D.R.2
  • 203
    • 79958260360 scopus 로고    scopus 로고
    • Communication impairments in mice lacking Shank1: Reduced levels of ultrasonic vocalizations and scent marking behavior
    • Wöhr M., Roullet F. I., Hung A. Y., Sheng M., and, Crawley J. N., (2011) Communication impairments in mice lacking Shank1: reduced levels of ultrasonic vocalizations and scent marking behavior. PLoS ONE 6, e20631.
    • (2011) PLoS ONE , vol.6
    • Wöhr, M.1    Roullet, F.I.2    Hung, A.Y.3    Sheng, M.4    Crawley, J.N.5
  • 204
    • 84862297282 scopus 로고    scopus 로고
    • Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function
    • Won H., Lee H. R., Gee H. Y., et al,. (2012) Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function. Nature 486, 261-265.
    • (2012) Nature , vol.486 , pp. 261-265
    • Won, H.1    Lee, H.R.2    Gee, H.Y.3
  • 205
    • 0032574841 scopus 로고    scopus 로고
    • A subclass of prefrontal gamma-aminobutyric acid axon terminals are selectively altered in schizophrenia
    • Woo T. U., Whitehead R. E., Melchitzky D. S., and, Lewis D. A., (1998) A subclass of prefrontal gamma-aminobutyric acid axon terminals are selectively altered in schizophrenia. Proc. Natl Acad. Sci. USA 95, 5341-5346.
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 5341-5346
    • Woo, T.U.1    Whitehead, R.E.2    Melchitzky, D.S.3    Lewis, D.A.4
  • 206
    • 3042782805 scopus 로고    scopus 로고
    • Density of glutamic acid decarboxylase 67 messenger RNA-containing neurons that express the N-methyl-D-aspartate receptor subunit NR2A in the anterior cingulate cortex in schizophrenia and bipolar disorder
    • Woo T. U., Walsh J. P., and, Benes F. M., (2004) Density of glutamic acid decarboxylase 67 messenger RNA-containing neurons that express the N-methyl-D-aspartate receptor subunit NR2A in the anterior cingulate cortex in schizophrenia and bipolar disorder. Arch. Gen. Psychiatry 61, 649-657.
    • (2004) Arch. Gen. Psychiatry , vol.61 , pp. 649-657
    • Woo, T.U.1    Walsh, J.P.2    Benes, F.M.3
  • 208
    • 72149094050 scopus 로고    scopus 로고
    • Kalirin loss results in cortical morphological alterations
    • Xie Z., Cahill M. E., and, Penzes P., (2010) Kalirin loss results in cortical morphological alterations. Mol. Cell. Neurosci. 43, 81-89.
    • (2010) Mol. Cell. Neurosci. , vol.43 , pp. 81-89
    • Xie, Z.1    Cahill, M.E.2    Penzes, P.3
  • 209
    • 0037369224 scopus 로고    scopus 로고
    • Neural development of the neuregulin receptor ErbB4 in the cerebral cortex and the hippocampus: Preferential expression by interneurons tangentially migrating from the ganglionic eminences
    • Yau H. J., Wang H. F., Lai C., and, Liu F. C., (2003) Neural development of the neuregulin receptor ErbB4 in the cerebral cortex and the hippocampus: preferential expression by interneurons tangentially migrating from the ganglionic eminences. Cereb. Cortex 13, 252-264.
    • (2003) Cereb. Cortex , vol.13 , pp. 252-264
    • Yau, H.J.1    Wang, H.F.2    Lai, C.3    Liu, F.C.4
  • 210
    • 34247631067 scopus 로고    scopus 로고
    • Decreased GAD67 mRNA levels in cerebellar Purkinje cells in autism: Pathophysiological implications
    • Yip J., Soghomonian J. J., and, Blatt G. J., (2007) Decreased GAD67 mRNA levels in cerebellar Purkinje cells in autism: pathophysiological implications. Acta Neuropathol. 113, 559-568.
    • (2007) Acta Neuropathol. , vol.113 , pp. 559-568
    • Yip, J.1    Soghomonian, J.J.2    Blatt, G.J.3
  • 211
    • 80052563319 scopus 로고    scopus 로고
    • Neocortical excitation/inhibition balance in information processing and social dysfunction
    • Yizhar O., Fenno L. E., Prigge M., et al,. (2011) Neocortical excitation/inhibition balance in information processing and social dysfunction. Nature 477, 171-178.
    • (2011) Nature , vol.477 , pp. 171-178
    • Yizhar, O.1    Fenno, L.E.2    Prigge, M.3
  • 212
    • 80053025841 scopus 로고    scopus 로고
    • IL-1 Receptor Accessory Protein-Like 1 Associated with Mental Retardation and Autism Mediates Synapse Formation by Trans-Synaptic Interaction with Protein Tyrosine Phosphatase {delta}
    • Yoshida T., Yasumura M., Uemura T., Lee S. J., Ra M., Taguchi R., Iwakura Y., and, Mishina M., (2011) IL-1 Receptor Accessory Protein-Like 1 Associated with Mental Retardation and Autism Mediates Synapse Formation by Trans-Synaptic Interaction with Protein Tyrosine Phosphatase {delta}. J. Neurosci. 31, 13485-13499.
    • (2011) J. Neurosci. , vol.31 , pp. 13485-13499
    • Yoshida, T.1    Yasumura, M.2    Uemura, T.3    Lee, S.J.4    Ra, M.5    Taguchi, R.6    Iwakura, Y.7    Mishina, M.8
  • 214
    • 0033968407 scopus 로고    scopus 로고
    • A new gene involved in X-linked mental retardation identified by analysis of an X;2 balanced translocation
    • Zemni R., Bienvenu T., Vinet M. C., et al,. (2000) A new gene involved in X-linked mental retardation identified by analysis of an X;2 balanced translocation. Nat. Genet. 24, 167-170.
    • (2000) Nat. Genet. , vol.24 , pp. 167-170
    • Zemni, R.1    Bienvenu, T.2    Vinet, M.C.3
  • 215
    • 77956587739 scopus 로고    scopus 로고
    • Abeta oligomers cause localized Ca(2+) elevation, missorting of endogenous Tau into dendrites, Tau phosphorylation, and destruction of microtubules and spines
    • Zempel H., Thies E., Mandelkow E., and, Mandelkow E. M., (2010) Abeta oligomers cause localized Ca(2+) elevation, missorting of endogenous Tau into dendrites, Tau phosphorylation, and destruction of microtubules and spines. J. Neurosci. 30, 11938-11950.
    • (2010) J. Neurosci. , vol.30 , pp. 11938-11950
    • Zempel, H.1    Thies, E.2    Mandelkow, E.3    Mandelkow, E.M.4
  • 216
    • 31544476561 scopus 로고    scopus 로고
    • Role of p21-activated kinase pathway defects in the cognitive deficits of Alzheimer disease
    • Zhao L., Ma Q. L., Calon F., et al,. (2006) Role of p21-activated kinase pathway defects in the cognitive deficits of Alzheimer disease. Nat. Neurosci. 9, 234-242.
    • (2006) Nat. Neurosci. , vol.9 , pp. 234-242
    • Zhao, L.1    Ma, Q.L.2    Calon, F.3
  • 217
    • 17444373481 scopus 로고    scopus 로고
    • Development of long-term dendritic spine stability in diverse regions of cerebral cortex
    • Zuo Y., Lin A., Chang P., and, Gan W. B., (2005) Development of long-term dendritic spine stability in diverse regions of cerebral cortex. Neuron 46, 181-189.
    • (2005) Neuron , vol.46 , pp. 181-189
    • Zuo, Y.1    Lin, A.2    Chang, P.3    Gan, W.B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.