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Volumn 7, Issue 2, 2005, Pages 165-179

Intermediate phenotypes in schizophrenia: A selective review

Author keywords

Cognition; Electrophysiology; Genetics; Morphometry; Neuroimaging; Neuropsychology; Phenotype; Schizophrenia

Indexed keywords

CATECHOL METHYLTRANSFERASE; RGS PROTEIN; RGS4 PROTEIN; UNCLASSIFIED DRUG;

EID: 21844450880     PISSN: 12948322     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (54)

References (124)
  • 2
    • 0038823525 scopus 로고    scopus 로고
    • The endophenotype concept in psychiatry: Etymology and strategic intentions
    • Gottesman, II, Gould TD. The endophenotype concept in psychiatry: etymology and strategic intentions. Am J Psychiatry. 2003;160:636-645.
    • (2003) Am J Psychiatry , vol.160 , pp. 636-645
    • Gottesman, I.I.1    Gould, T.D.2
  • 3
    • 0027484221 scopus 로고
    • Use of a neurophysiological trait in linkage analysis of schizophrenia
    • Coon H, Plaetke R, Holik J, et al. Use of a neurophysiological trait in linkage analysis of schizophrenia. Biol Psychiatry. 1993;34:277-289.
    • (1993) Biol Psychiatry , vol.34 , pp. 277-289
    • Coon, H.1    Plaetke, R.2    Holik, J.3
  • 4
    • 0028107369 scopus 로고
    • Event-related potential abnormalities correlate with structural brain alterations and clinical features in patients with chronic schizophrenia
    • Egan MF, Duncan CC, Suddath RL, Kirch DG, Mirsky AF, Wyatt RJ. Event-related potential abnormalities correlate with structural brain alterations and clinical features in patients with chronic schizophrenia. Schizophr Res. 1994;11:259-271.
    • (1994) Schizophr Res , vol.11 , pp. 259-271
    • Egan, M.F.1    Duncan, C.C.2    Suddath, R.L.3    Kirch, D.G.4    Mirsky, A.F.5    Wyatt, R.J.6
  • 7
    • 0036773740 scopus 로고    scopus 로고
    • Twin and family studies of the human electroencephalogram: A review and meta-analysis
    • van Beijsterveldt CEM, van Baal GCM. Twin and family studies of the human electroencephalogram: a review and meta-analysis. Biol Psychol. 2002;61:111-138.
    • (2002) Biol Psychol , vol.61 , pp. 111-138
    • Van Beijsterveldt, C.E.M.1    Van Baal, G.C.M.2
  • 8
    • 0035825219 scopus 로고    scopus 로고
    • Endophenotypes as quantitative risk factors for psychiatric disease: Rationale and study design
    • Almasy L, Blangero J. Endophenotypes as quantitative risk factors for psychiatric disease: rationale and study design. Am J Med Genet. 2001;105:42-44.
    • (2001) Am J Med Genet , vol.105 , pp. 42-44
    • Almasy, L.1    Blangero, J.2
  • 9
    • 0035825211 scopus 로고    scopus 로고
    • Impaired attention as an endophenotype for molecular genetic studies of schizophrenia
    • Cornblatt BA, Malhotra AK. Impaired attention as an endophenotype for molecular genetic studies of schizophrenia. Am J Med Genet. 2001;105:11.
    • (2001) Am J Med Genet , vol.105 , pp. 11
    • Cornblatt, B.A.1    Malhotra, A.K.2
  • 10
    • 12344327212 scopus 로고    scopus 로고
    • Schizophrenia genes, gene expression, and neuropathology: On the matter of their convergence
    • Harrison PJ, Weinberger DR. Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence. Mol Psychiatry. 2005;10:40-68.
    • (2005) Mol Psychiatry , vol.10 , pp. 40-68
    • Harrison, P.J.1    Weinberger, D.R.2
  • 11
    • 0032924127 scopus 로고    scopus 로고
    • The neuropathology of schizophrenia. A critical review of the data and their interpretation
    • Harrison PJ. The neuropathology of schizophrenia. A critical review of the data and their interpretation. Brain. 1999;122(Pt 4):593-624.
    • (1999) Brain , vol.122 , Issue.PART 4 , pp. 593-624
    • Harrison, P.J.1
  • 12
    • 2342538196 scopus 로고    scopus 로고
    • The hippocampus in schizophrenia: A review of the neuropathological evidence and its pathophysiological implications
    • Harrison PJ. The hippocampus in schizophrenia: a review of the neuropathological evidence and its pathophysiological implications. Psychopharmacology (Berl). 2004;174:151-162.
    • (2004) Psychopharmacology (Berl) , vol.174 , pp. 151-162
    • Harrison, P.J.1
  • 13
    • 12344310981 scopus 로고    scopus 로고
    • Schizophrenia genes within cortical neural circuits
    • Harrison PJ, Weinberger DR. Schizophrenia genes within cortical neural circuits. Mol Psychiatry. 2005;10:1-4.
    • (2005) Mol Psychiatry , vol.10 , pp. 1-4
    • Harrison, P.J.1    Weinberger, D.R.2
  • 14
    • 0037209127 scopus 로고    scopus 로고
    • Intermediate cognitive phenotypes associated with schizophrenia
    • Egan MF, Goldberg TE. Intermediate cognitive phenotypes associated with schizophrenia. Methods Mol Med. 2003;77:163-197.
    • (2003) Methods Mol Med , vol.77 , pp. 163-197
    • Egan, M.F.1    Goldberg, T.E.2
  • 18
    • 0029118785 scopus 로고
    • Genetic risk of neuropsychological impairment in schizophrenia: A study of monozygotic twins discordant and concordant for the disorder
    • Goldberg TE, Torrey EF, Gold JM, et al. Genetic risk of neuropsychological impairment in schizophrenia: a study of monozygotic twins discordant and concordant for the disorder. Schizophr Res. 1995;17:77-84.
    • (1995) Schizophr Res , vol.17 , pp. 77-84
    • Goldberg, T.E.1    Torrey, E.F.2    Gold, J.M.3
  • 19
    • 2342504605 scopus 로고    scopus 로고
    • A polymorphism in the cyclooxygenase 2 gene as an inherited protective factor against myocardial infarction and stroke
    • Cipollone F, Toniato E, Martinotti S, et al. A polymorphism in the cyclooxygenase 2 gene as an inherited protective factor against myocardial infarction and stroke. JAMA. 2004;291:2221-2285.
    • (2004) JAMA , vol.291 , pp. 2221-2285
    • Cipollone, F.1    Toniato, E.2    Martinotti, S.3
  • 21
    • 14744289046 scopus 로고    scopus 로고
    • Role of the FOXC2 -512C>T polymorphism in type 2 diabetes: Possible association with the dysmetabolic syndrome
    • Carlsson E, Groop L, Ridderstrale M. Role of the FOXC2 -512C>T polymorphism in type 2 diabetes: possible association with the dysmetabolic syndrome. Int J Obes Relat Metab Disord. 2005;29:268-274.
    • (2005) Int J Obes Relat Metab Disord , vol.29 , pp. 268-274
    • Carlsson, E.1    Groop, L.2    Ridderstrale, M.3
  • 22
    • 12944308811 scopus 로고    scopus 로고
    • Common polymorphisms of the PPAR-gamma2 (Pro12Ala) and PGC-1alpha (Gly482Ser) genes are associated with the conversion from impaired glucose tolerance to type 2 diabetes in the STOP-NIDDM trial
    • Andrulionyte L, Zacharova J, Chiasson JL, Laakso M. Common polymorphisms of the PPAR-gamma2 (Pro12Ala) and PGC-1alpha (Gly482Ser) genes are associated with the conversion from impaired glucose tolerance to type 2 diabetes in the STOP-NIDDM trial. Diabetologia. 2004;47:2176-2184.
    • (2004) Diabetologia , vol.47 , pp. 2176-2184
    • Andrulionyte, L.1    Zacharova, J.2    Chiasson, J.L.3    Laakso, M.4
  • 23
    • 2542560427 scopus 로고    scopus 로고
    • Hereditary hemochromatosis-A new look at an old disease
    • Pietrangelo A. Hereditary hemochromatosis-a new look at an old disease. N Engl J Med. 2004;350:2383-2397.
    • (2004) N Engl J Med , vol.350 , pp. 2383-2397
    • Pietrangelo, A.1
  • 24
    • 0023751711 scopus 로고
    • A screening test for detecting iron overload in population studies
    • Baynes RD, Meyer TE, Bothwell TH, McNamara L. A screening test for detecting iron overload in population studies. S Afr Med J. 1988;74:167-169.
    • (1988) S Afr Med J , vol.74 , pp. 167-169
    • Baynes, R.D.1    Meyer, T.E.2    Bothwell, T.H.3    McNamara, L.4
  • 25
    • 0038542813 scopus 로고    scopus 로고
    • The HFE Cys282Tyr mutation as a necessary but not sufficient cause of clinical hereditary hemochromatosis
    • Beutler E. The HFE Cys282Tyr mutation as a necessary but not sufficient cause of clinical hereditary hemochromatosis. Blood. 2003;101:3347-3350.
    • (2003) Blood , vol.101 , pp. 3347-3350
    • Beutler, E.1
  • 26
    • 17044421761 scopus 로고    scopus 로고
    • Haptoglobin modifies the hemochromatosis phenotype in mice
    • Tolosano E, Fagoonee S, Garuti C, et al. Haptoglobin modifies the hemochromatosis phenotype in mice. Blood. 2005;105:3353-3355.
    • (2005) Blood , vol.105 , pp. 3353-3355
    • Tolosano, E.1    Fagoonee, S.2    Garuti, C.3
  • 27
    • 0042130064 scopus 로고    scopus 로고
    • Cognitive and symptom predictors of work outcomes for clients with schizophrenia in supported employment
    • McGurk SR, Mueser KT, Harvey PD, LaPuglia R, Marder J. Cognitive and symptom predictors of work outcomes for clients with schizophrenia in supported employment. Psychiatr Serv. 2003;54:1129-1135.
    • (2003) Psychiatr Serv , vol.54 , pp. 1129-1135
    • McGurk, S.R.1    Mueser, K.T.2    Harvey, P.D.3    Lapuglia, R.4    Marder, J.5
  • 28
    • 0034122979 scopus 로고    scopus 로고
    • Relationship of cognitive functioning, adaptive life skills, and negative symptom severity in poor-outcome geriatric schizophrenia patients
    • McGurk SR, Moriarty PJ, Harvey PD, et al. Relationship of cognitive functioning, adaptive life skills, and negative symptom severity in poor-outcome geriatric schizophrenia patients. J Neuropsychiatry Clin Neurosci. 2000;12:257-264.
    • (2000) J Neuropsychiatry Clin Neurosci , vol.12 , pp. 257-264
    • McGurk, S.R.1    Moriarty, P.J.2    Harvey, P.D.3
  • 29
    • 0034000111 scopus 로고    scopus 로고
    • The longitudinal relationship of clinical symptoms, cognitive functioning, and adaptive life in geriatric schizophrenia
    • McGurk SR, Moriarty PJ, Harvey PD, Parrella M, White L, Davis KL. The longitudinal relationship of clinical symptoms, cognitive functioning, and adaptive life in geriatric schizophrenia. Schizophr Res. 2000;42:47-55.
    • (2000) Schizophr Res , vol.42 , pp. 47-55
    • McGurk, S.R.1    Moriarty, P.J.2    Harvey, P.D.3    Parrella, M.4    White, L.5    Davis, K.L.6
  • 30
    • 0037329184 scopus 로고    scopus 로고
    • Initial and final work performance in schizophrenia: Cognitive and symptom predictors
    • Bryson G, Bell MD. Initial and final work performance in schizophrenia: cognitive and symptom predictors. J Nerv Ment Dis. 2003;191:8-92.
    • (2003) J Nerv Ment Dis , vol.191 , pp. 8-92
    • Bryson, G.1    Bell, M.D.2
  • 32
    • 0033866340 scopus 로고    scopus 로고
    • The inheritance of neuropsychological dysfunction in twins discordant for schizophrenia
    • Cannon TD, Huttunen MO, Lonnqvist J, et al. The inheritance of neuropsychological dysfunction in twins discordant for schizophrenia. Am J Hum Genet. 2000;67:369-382.
    • (2000) Am J Hum Genet , vol.67 , pp. 369-382
    • Cannon, T.D.1    Huttunen, M.O.2    Lonnqvist, J.3
  • 33
    • 3042778314 scopus 로고    scopus 로고
    • Genes and the parsing of cognitive processes
    • Goldberg TE, Weinberger DR. Genes and the parsing of cognitive processes. Trends Cogn Sci. 2004;8:325-335.
    • (2004) Trends Cogn Sci , vol.8 , pp. 325-335
    • Goldberg, T.E.1    Weinberger, D.R.2
  • 34
    • 0033843102 scopus 로고    scopus 로고
    • Relative risk of attention deficits in siblings of patients with schizophrenia
    • Egan MF. Relative risk of attention deficits in siblings of patients with schizophrenia. Am J Psychiatry. 2000;157:1309-1316.
    • (2000) Am J Psychiatry , vol.157 , pp. 1309-1316
    • Egan, M.F.1
  • 35
    • 0035878548 scopus 로고    scopus 로고
    • Relative risk for cognitive impairments in siblings of patients with schizophrenia
    • Egan MF, Goldberg TE, Gscheidle T, et al. Relative risk for cognitive impairments in siblings of patients with schizophrenia. Biol Psychiatry. 2001;50:98-107.
    • (2001) Biol Psychiatry , vol.50 , pp. 98-107
    • Egan, M.F.1    Goldberg, T.E.2    Gscheidle, T.3
  • 37
    • 0343924491 scopus 로고    scopus 로고
    • Attentional dysfunctions in neuroleptic-naive and neuroleptic-withdrawn schizophrenic patients and their siblings
    • Finkelstein JR, Cannon TD, Gur RE, Gur RC, Moberg P. Attentional dysfunctions in neuroleptic-naive and neuroleptic-withdrawn schizophrenic patients and their siblings. J Abnorm Psychol. 1997;106:203-212.
    • (1997) J Abnorm Psychol , vol.106 , pp. 203-212
    • Finkelstein, J.R.1    Cannon, T.D.2    Gur, R.E.3    Gur, R.C.4    Moberg, P.5
  • 38
    • 0033763181 scopus 로고    scopus 로고
    • Neuropsychological deficit in siblings discordant for schizophrenia
    • Saoud M, d'Amato T, Gutknecht C, et al. Neuropsychological deficit in siblings discordant for schizophrenia. Schizophr Bull. 2000;26:893-902.
    • (2000) Schizophr Bull , vol.26 , pp. 893-902
    • Saoud, M.1    D'Amato, T.2    Gutknecht, C.3
  • 39
    • 0031907796 scopus 로고    scopus 로고
    • Performance of the continuous performance test among community samples
    • Chen WJ, Hsiao CK, Hsiao LL, Hwu HG. Performance of the continuous performance test among community samples. Schizophr Bull. 1998;24:1-74.
    • (1998) Schizophr Bull , vol.24 , pp. 1-74
    • Chen, W.J.1    Hsiao, C.K.2    Hsiao, L.L.3    Hwu, H.G.4
  • 42
    • 0029042834 scopus 로고
    • Neuropsychological functioning among the nonpsychotic relatives of schizophrenic patients: A diagnostic efficiency analysis
    • Faraone SV, Seidman LJ, Kremen WS, Pepple JR, Lyons MJ, Tsuang MT. Neuropsychological functioning among the nonpsychotic relatives of schizophrenic patients: a diagnostic efficiency analysis. J Abnorm Psychol. 1995;104:286-304.
    • (1995) J Abnorm Psychol , vol.104 , pp. 286-304
    • Faraone, S.V.1    Seidman, L.J.2    Kremen, W.S.3    Pepple, J.R.4    Lyons, M.J.5    Tsuang, M.T.6
  • 44
    • 0026558228 scopus 로고
    • Using vulnerability indicators to compare conceptual models of genetic heterogeneity in schizophrenia
    • Kremen WS, Tsuang MT, Faraone SV, Lyons MJ. Using vulnerability indicators to compare conceptual models of genetic heterogeneity in schizophrenia. J Nerv Ment Dis. 1992;180:141-152.
    • (1992) J Nerv Ment Dis , vol.180 , pp. 141-152
    • Kremen, W.S.1    Tsuang, M.T.2    Faraone, S.V.3    Lyons, M.J.4
  • 45
    • 3242813609 scopus 로고    scopus 로고
    • Critical evaluation of cognitive dysfunctions as endophenotypes of schizophrenia
    • Keri S, Janka Z. Critical evaluation of cognitive dysfunctions as endophenotypes of schizophrenia. Acta Psychiatr Scand. 2004;110:83-91.
    • (2004) Acta Psychiatr Scand , vol.110 , pp. 83-91
    • Keri, S.1    Janka, Z.2
  • 46
    • 84921009118 scopus 로고
    • Cerebral ventricular size and cognitive impairment in chronic schizophrenia
    • Johnstone EC, Crow TJ, Frith CD, Husband J, Kreel L. Cerebral ventricular size and cognitive impairment in chronic schizophrenia. Lancet. 1976;2:924-926.
    • (1976) Lancet , vol.2 , pp. 924-926
    • Johnstone, E.C.1    Crow, T.J.2    Frith, C.D.3    Husband, J.4    Kreel, L.5
  • 48
    • 0020073394 scopus 로고
    • Cerebral ventricular size in twins discordant for schizophrenia
    • Reveley AM, Reveley MA, Clifford CA, Murray RM. Cerebral ventricular size in twins discordant for schizophrenia. Lancet. 1982;8271:540-541.
    • (1982) Lancet , vol.8271 , pp. 540-541
    • Reveley, A.M.1    Reveley, M.A.2    Clifford, C.A.3    Murray, R.M.4
  • 49
    • 1442284210 scopus 로고    scopus 로고
    • Gray and white matter volume abnormalities in monozygotic and same-gender dizygotic twins discordant for schizophrenia
    • Hulshoff Pol HE, Brans RG, van Haren NE, et al. Gray and white matter volume abnormalities in monozygotic and same-gender dizygotic twins discordant for schizophrenia. Biol Psychiatry. 2004;55:126-130.
    • (2004) Biol Psychiatry , vol.55 , pp. 126-130
    • Hulshoff Pol, H.E.1    Brans, R.G.2    Van Haren, N.E.3
  • 50
    • 0029940479 scopus 로고    scopus 로고
    • Fetal brain development of twins assessed in utero by ultrasound: Implications for schizophrenia
    • Gilmore JH, Perkins DO, Kliewer MA, et al. Fetal brain development of twins assessed in utero by ultrasound: implications for schizophrenia. Schizophr Res. 1996;19:141-149.
    • (1996) Schizophr Res , vol.19 , pp. 141-149
    • Gilmore, J.H.1    Perkins, D.O.2    Kliewer, M.A.3
  • 52
    • 0029853927 scopus 로고    scopus 로고
    • Regionally specific pattern of neurochemical pathology in schizophrenia as assessed by multislice proton magnetic resonance spectroscopic imaging
    • Bertolino A, Nawroz S, Mattay VS, et al. Regionally specific pattern of neurochemical pathology in schizophrenia as assessed by multislice proton magnetic resonance spectroscopic imaging. Am J Psychiatry. 1996;153:1554-1563.
    • (1996) Am J Psychiatry , vol.153 , pp. 1554-1563
    • Bertolino, A.1    Nawroz, S.2    Mattay, V.S.3
  • 53
    • 0033961240 scopus 로고    scopus 로고
    • Specific relationship between prefrontal neuronal N-acetylaspartate and activation of the working memory cortical network in schizophrenia
    • Bertolino A, Esposito G, Callicott JH, et al. Specific relationship between prefrontal neuronal N-acetylaspartate and activation of the working memory cortical network in schizophrenia. Am J Psychiatry. 2000;157:26-33.
    • (2000) Am J Psychiatry , vol.157 , pp. 26-33
    • Bertolino, A.1    Esposito, G.2    Callicott, J.H.3
  • 54
    • 0032533636 scopus 로고    scopus 로고
    • Hippocampal N-acetyl aspartate in unaffected siblings of patients with schizophrenia: A possible intermediate neurobiological phenotype
    • Callicott JH, Egan MF, Bertolino A, et al. Hippocampal N-acetyl aspartate in unaffected siblings of patients with schizophrenia: a possible intermediate neurobiological phenotype. Biol Psychiatry. 1998;44:941-950.
    • (1998) Biol Psychiatry , vol.44 , pp. 941-950
    • Callicott, J.H.1    Egan, M.F.2    Bertolino, A.3
  • 55
    • 0038734204 scopus 로고    scopus 로고
    • An expanded role for functional neuroimaging in schizophrenia
    • Callicott JH. An expanded role for functional neuroimaging in schizophrenia. Curr Opin Neurobiol. 2003;13:256-260.
    • (2003) Curr Opin Neurobiol , vol.13 , pp. 256-260
    • Callicott, J.H.1
  • 56
    • 0038474159 scopus 로고    scopus 로고
    • Abnormal fMRI response of the dorsolateral prefrontal cortex in cognitively intact siblings of patients with schizophrenia
    • Callicott JH, Egan MF, Mattay VS, et al. Abnormal fMRI response of the dorsolateral prefrontal cortex in cognitively intact siblings of patients with schizophrenia Am J Psychiatry. 2003;160:709-719.
    • (2003) Am J Psychiatry , vol.160 , pp. 709-719
    • Callicott, J.H.1    Egan, M.F.2    Mattay, V.S.3
  • 57
    • 0038182459 scopus 로고    scopus 로고
    • An FMRI study of episodic encoding and recognition of words in patients with schizophrenia in remission
    • Hofer A, Weiss EM, Golaszewski SM, et al. An FMRI study of episodic encoding and recognition of words in patients with schizophrenia in remission. Am J Psychiatry. 2003;160:911-918.
    • (2003) Am J Psychiatry , vol.160 , pp. 911-918
    • Hofer, A.1    Weiss, E.M.2    Golaszewski, S.M.3
  • 58
    • 2942564078 scopus 로고    scopus 로고
    • Event-related fMRI of frontotemporal activity during word encoding and recognition in schizophrenia
    • Ragland JD, Gur RC, Valdez J, et al. Event-related fMRI of frontotemporal activity during word encoding and recognition in schizophrenia. Am J Psychiatry. 2004;161:1004-1015.
    • (2004) Am J Psychiatry , vol.161 , pp. 1004-1015
    • Ragland, J.D.1    Gur, R.C.2    Valdez, J.3
  • 59
    • 13844299198 scopus 로고    scopus 로고
    • The effect of working memory performance on functional MRI in schizophrenia
    • Thermenos HW, Goldstein JM, Buka SL, et al. The effect of working memory performance on functional MRI in schizophrenia. Schizophr Res. 2005;74:179-194.
    • (2005) Schizophr Res , vol.74 , pp. 179-194
    • Thermenos, H.W.1    Goldstein, J.M.2    Buka, S.L.3
  • 60
    • 0019995306 scopus 로고
    • Neurophysiological evidence for a defect in neuronal mechanisms involved in sensory gating in schizophrenia
    • Adler LE PE, Franks RD, Pecevich M, Waldo MC, Freedman R. Neurophysiological evidence for a defect in neuronal mechanisms involved in sensory gating in schizophrenia. Biol Psychiatry. 1982;17:639-654.
    • (1982) Biol Psychiatry , vol.17 , pp. 639-654
    • Adler, L.E.P.E.1    Franks, R.D.2    Pecevich, M.3    Waldo, M.C.4    Freedman, R.5
  • 61
    • 0021234214 scopus 로고
    • Deficits in sensory gating in schizophrenic patients and their relatives. Evidence obtained with auditory evoked responses
    • Siegel C, Waldo M, Mizner G, Adler LE, Freedman R. Deficits in sensory gating in schizophrenic patients and their relatives. Evidence obtained with auditory evoked responses. Arch Gen Psychiatry. 1984;41:607-612.
    • (1984) Arch Gen Psychiatry , vol.41 , pp. 607-612
    • Siegel, C.1    Waldo, M.2    Mizner, G.3    Adler, L.E.4    Freedman, R.5
  • 62
    • 0023551453 scopus 로고
    • Neurobiological studies of sensory gating in schizophrenia
    • Freedman R, Adler LE, Gerhardt GA, et al. Neurobiological studies of sensory gating in schizophrenia. Schizophr Bull. 1987;13:669-678.
    • (1987) Schizophr Bull , vol.13 , pp. 669-678
    • Freedman, R.1    Adler, L.E.2    Gerhardt, G.A.3
  • 63
    • 0036897083 scopus 로고    scopus 로고
    • P50 sensory gating in multiplex schizophrenia families from a Pacific island isolate
    • Myles-Worsley M. P50 sensory gating in multiplex schizophrenia families from a Pacific island isolate. Am J Psychiatry. 2002;159:2007-2012.
    • (2002) Am J Psychiatry , vol.159 , pp. 2007-2012
    • Myles-Worsley, M.1
  • 64
    • 0032724777 scopus 로고    scopus 로고
    • Comparison of four components of sensory gating in schizophrenia and normal subjects: A preliminary report
    • Boutros NN, Belger A, Campbell D, D'Souza C, Krystal J. Comparison of four components of sensory gating in schizophrenia and normal subjects: a preliminary report. Psychiatry Res. 1999;88:119-130.
    • (1999) Psychiatry Res , vol.88 , pp. 119-130
    • Boutros, N.N.1    Belger, A.2    Campbell, D.3    D'Souza, C.4    Krystal, J.5
  • 65
    • 0034895958 scopus 로고    scopus 로고
    • Multichannel electroencephalographic assessment of auditory evoked response suppression in schizophrenia
    • Clementz BA, Blumenfeld LD. Multichannel electroencephalographic assessment of auditory evoked response suppression in schizophrenia. Exp Brain Res. 2001;139:377-390.
    • (2001) Exp Brain Res , vol.139 , pp. 377-390
    • Clementz, B.A.1    Blumenfeld, L.D.2
  • 67
    • 0034013468 scopus 로고    scopus 로고
    • Inhibitory neurophysiological deficit as a phenotype for genetic investigation of schizophrenia
    • Freedman R, Adams CE, Adler LE, et al. Inhibitory neurophysiological deficit as a phenotype for genetic investigation of schizophrenia. Am J Med Genet. 2000;97:58-64.
    • (2000) Am J Med Genet , vol.97 , pp. 58-64
    • Freedman, R.1    Adams, C.E.2    Adler, L.E.3
  • 68
    • 0026472046 scopus 로고
    • Normalization by nicotine of deficient auditory sensory gating in the relatives of schizophrenics
    • Adler LE, Hoffer U, Griffith J, Waldo MC, Freedman R. Normalization by nicotine of deficient auditory sensory gating in the relatives of schizophrenics. Biol Psychiatry. 1992;32:607-616.
    • (1992) Biol Psychiatry , vol.32 , pp. 607-616
    • Adler, L.E.1    Hoffer, U.2    Griffith, J.3    Waldo, M.C.4    Freedman, R.5
  • 69
    • 1642417429 scopus 로고    scopus 로고
    • P50 sensory gating in adolescents from a pacific island isolate with elevated risk for schizophrenia
    • Myles-Worsley M, Ord L, Blailes F, Ngiralmau H, Freedman R. P50 sensory gating in adolescents from a pacific island isolate with elevated risk for schizophrenia. Biol Psychiatry. 2004;55:663-667.
    • (2004) Biol Psychiatry , vol.55 , pp. 663-667
    • Myles-Worsley, M.1    Ord, L.2    Blailes, F.3    Ngiralmau, H.4    Freedman, R.5
  • 70
    • 0036897309 scopus 로고    scopus 로고
    • 7 nicotinic acetylcholine receptor subunit gene with an inhibitory deficit found in schizophrenia
    • 7 nicotinic acetylcholine receptor subunit gene with an inhibitory deficit found in schizophrenia. Arch Gen Psychiatry. 2002;59:1085-1096.
    • (2002) Arch Gen Psychiatry , vol.59 , pp. 1085-1096
    • Leonard, S.1    Gault, J.2    Hopkins, J.3
  • 71
    • 0036428860 scopus 로고    scopus 로고
    • 7-like" nicotinic receptor subunit gene is a risk factor for the P50 sensory gating deficit
    • 7-like" nicotinic receptor subunit gene is a risk factor for the P50 sensory gating deficit. Mol Psychiatry. 2002;7:1006-1011.
    • (2002) Mol Psychiatry , vol.7 , pp. 1006-1011
    • Raux, G.1    Bonnet-Brilhault, F.2    Louchant, S.3
  • 72
    • 11144356494 scopus 로고    scopus 로고
    • The promoter -194 C polymorphism of the nicotinic α7 receptor gene has a protective effect against the P50 sensory gating deficit
    • Houy E, Raux G, Thibaut F, et al. The promoter -194 C polymorphism of the nicotinic α7 receptor gene has a protective effect against the P50 sensory gating deficit. Mol Pyschiatry. 2004;9:320-322.
    • (2004) Mol Pyschiatry , vol.9 , pp. 320-322
    • Houy, E.1    Raux, G.2    Thibaut, F.3
  • 73
    • 3242806757 scopus 로고    scopus 로고
    • Clinical phenotypes associated with DISC1, a candidate gene for schizophrenia
    • Blackwood DH, Muir MW. Clinical phenotypes associated with DISC1, a candidate gene for schizophrenia. Neurotox Res. 2004;6:35-41.
    • (2004) Neurotox Res , vol.6 , pp. 35-41
    • Blackwood, D.H.1    Muir, M.W.2
  • 75
    • 0032747786 scopus 로고    scopus 로고
    • Schizophrenia: The broken P300 and beyond
    • Ford JM. Schizophrenia: the broken P300 and beyond. Psychophysiology. 1999;36:667-682.
    • (1999) Psychophysiology , vol.36 , pp. 667-682
    • Ford, J.M.1
  • 76
    • 0033968525 scopus 로고    scopus 로고
    • Alteration of event related potentials in siblings discordant for schizophrenia
    • Karoumi B, Laurent A, Rosenfeld F, et al. Alteration of event related potentials in siblings discordant for schizophrenia. Schizophr Res. 2000;41:325-334.
    • (2000) Schizophr Res , vol.41 , pp. 325-334
    • Karoumi, B.1    Laurent, A.2    Rosenfeld, F.3
  • 78
    • 0031974865 scopus 로고    scopus 로고
    • P300 subcomponent abnormalities in schizophrenia: II. Longitudinal stability and relationship to symptom change
    • Turetsky B, Colbath EA, Gur RE. P300 subcomponent abnormalities in schizophrenia: II. Longitudinal stability and relationship to symptom change. Biol Psychiatry. 1998;43:31-39.
    • (1998) Biol Psychiatry , vol.43 , pp. 31-39
    • Turetsky, B.1    Colbath, E.A.2    Gur, R.E.3
  • 79
    • 0033951983 scopus 로고    scopus 로고
    • P300 subcomponent abnormalities in schizophrenia: III. Deficits in unaffected siblings of schizophrenic probands
    • Turetsky Bl, Cannon TD, Gur RE. P300 subcomponent abnormalities in schizophrenia: III. Deficits in unaffected siblings of schizophrenic probands. Biol Psychiatry. 2000;47:380-390.
    • (2000) Biol Psychiatry , vol.47 , pp. 380-390
    • Bl, T.1    Cannon, T.D.2    Gur, R.E.3
  • 80
    • 5044225291 scopus 로고    scopus 로고
    • Genes, dopamine and cortical signal-to-noise ratio in schizophrenia
    • Winterer G, Weinberger DR. Genes, dopamine and cortical signal-to-noise ratio in schizophrenia. Trends Neurosci. 2004;27:683-690.
    • (2004) Trends Neurosci , vol.27 , pp. 683-690
    • Winterer, G.1    Weinberger, D.R.2
  • 81
    • 0035177944 scopus 로고    scopus 로고
    • Neuropathological studies of synaptic connectivity in the hippocampal formation in schizophrenia
    • Harrison PJ, Eastwood SL. Neuropathological studies of synaptic connectivity in the hippocampal formation in schizophrenia. Hippocampus. 2001;11:508-519.
    • (2001) Hippocampus , vol.11 , pp. 508-519
    • Harrison, P.J.1    Eastwood, S.L.2
  • 82
    • 0034098526 scopus 로고    scopus 로고
    • GABAergic local circuit neurons and prefrontal cortical dysfunction in schizophrenia
    • Lewis DA. GABAergic local circuit neurons and prefrontal cortical dysfunction in schizophrenia. Brain Res Brain Res Rev. 2000;31:270-276.
    • (2000) Brain Res Brain Res Rev , vol.31 , pp. 270-276
    • Lewis, D.A.1
  • 83
    • 2342522657 scopus 로고    scopus 로고
    • Presynaptic proteins and schizophrenia
    • Amsterdam, The Netherlands: Elsevier
    • Honer WG. Presynaptic proteins and schizophrenia. In: Disorders of Synaptic Plasticity and Schizophrenia. Vol 59. Amsterdam, The Netherlands: Elsevier; 2004.
    • (2004) Disorders of Synaptic Plasticity and Schizophrenia , vol.59
    • Honer, W.G.1
  • 84
    • 0035426751 scopus 로고    scopus 로고
    • Analysis of complex brain disorders with gene expression microarrays: Schizophrenia as a disease of the synapse
    • Mimics K, Middleton FA, Lewis DA, Levitt P. Analysis of complex brain disorders with gene expression microarrays: schizophrenia as a disease of the synapse. Trends Neurosci. 2001;24:479-486.
    • (2001) Trends Neurosci , vol.24 , pp. 479-486
    • Mimics, K.1    Middleton, F.A.2    Lewis, D.A.3    Levitt, P.4
  • 85
    • 0002820468 scopus 로고    scopus 로고
    • The glial growth factors deficiency and synaptic destabilization hypothesis of schizophrenia
    • Moises HW, Zoega T, Gottesman II. The glial growth factors deficiency and synaptic destabilization hypothesis of schizophrenia. BMC Psychiatry. 2002;2:8.
    • (2002) BMC Psychiatry , vol.2 , pp. 8
    • Moises, H.W.1    Zoega, T.2    Gottesman, I.I.3
  • 86
    • 0042848912 scopus 로고    scopus 로고
    • The synaptic hypothesis of schizophrenia
    • Frankle WG, Lerma J, Laruelle M. The synaptic hypothesis of schizophrenia. Neuron. 2003;39:205-216.
    • (2003) Neuron , vol.39 , pp. 205-216
    • Frankle, W.G.1    Lerma, J.2    Laruelle, M.3
  • 87
    • 0038003196 scopus 로고    scopus 로고
    • Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia
    • Lewis CM, Levinson DF, Wise LH, et al. Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: schizophrenia. Am J Hum Genet. 2003;73:34-48.
    • (2003) Am J Hum Genet , vol.73 , pp. 34-48
    • Lewis, C.M.1    Levinson, D.F.2    Wise, L.H.3
  • 88
    • 0036258079 scopus 로고    scopus 로고
    • Meta-analysis of whole-genome linkage scans of bipolar disorder and schizophrenia
    • Badner JA, Gershon ES. Meta-analysis of whole-genome linkage scans of bipolar disorder and schizophrenia. Mol Psychiatry. 2002;7:405-411.
    • (2002) Mol Psychiatry , vol.7 , pp. 405-411
    • Badner, J.A.1    Gershon, E.S.2
  • 89
    • 0035810850 scopus 로고    scopus 로고
    • Effect of COMT Val108/158Met genotype on frontal lobe function and risk for schizophrenia
    • Egan MF, Goldberg TE, Kolachana BS, et al. Effect of COMT Val108/158Met genotype on frontal lobe function and risk for schizophrenia. Proc Natl Acad Sci U S A. 2001;98:6917-6922.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 6917-6922
    • Egan, M.F.1    Goldberg, T.E.2    Kolachana, B.S.3
  • 90
    • 0141791141 scopus 로고    scopus 로고
    • Executive subprocesses in working memory: Relationship to catechol-O-methyltransferase Val158Met genotype and schizophrenia
    • Goldberg TE, Egan MF, Gscheidle T, et al. Executive subprocesses in working memory: relationship to catechol-O-methyltransferase Val158Met genotype and schizophrenia. Arch Gen Psychiatry. 2003;60:889-896.
    • (2003) Arch Gen Psychiatry , vol.60 , pp. 889-896
    • Goldberg, T.E.1    Egan, M.F.2    Gscheidle, T.3
  • 91
    • 0034727878 scopus 로고    scopus 로고
    • Gene expression of metabotropic glutamate receptor 5 and excitatory amino acid transporter 2 in the schizophrenic hippocampus
    • Ohnuma T, Tessler S, Arai H, Faull RL, McKenna PJ, Emson PC. Gene expression of metabotropic glutamate receptor 5 and excitatory amino acid transporter 2 in the schizophrenic hippocampus. Brain Res Mol Brain Res. 2000;85:24-31.
    • (2000) Brain Res Mol Brain Res , vol.85 , pp. 24-31
    • Ohnuma, T.1    Tessler, S.2    Arai, H.3    Faull, R.L.4    McKenna, P.J.5    Emson, P.C.6
  • 92
    • 13244255399 scopus 로고    scopus 로고
    • Genetic polymorphisms of the RGS4 and dorsolateral prefrontal cortex morphometry among first episode schizophrenia patients
    • Prasad KM, Chowdari KV, Nimgaonkar VL, Talkowski ME, Lewis DA, Keshavan MS. Genetic polymorphisms of the RGS4 and dorsolateral prefrontal cortex morphometry among first episode schizophrenia patients. Mol Psychiatry. 2005;10:213-219.
    • (2005) Mol Psychiatry , vol.10 , pp. 213-219
    • Prasad, K.M.1    Chowdari, K.V.2    Nimgaonkar, V.L.3    Talkowski, M.E.4    Lewis, D.A.5    Keshavan, M.S.6
  • 93
    • 4344624909 scopus 로고    scopus 로고
    • Variation in GRM3 affects cognition, prefrontal glutamate, and risk for schizophrenia
    • Egan MF, Straub RE, Goldberg TE, et al. Variation in GRM3 affects cognition, prefrontal glutamate, and risk for schizophrenia. Proc Natl Acad Sci U S A. 2004;101:12604-12609.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 12604-12609
    • Egan, M.F.1    Straub, R.E.2    Goldberg, T.E.3
  • 94
    • 0024392625 scopus 로고
    • Frontal cortical and left temporal glutamatergic dysfunction in schizophrenia
    • Deakin JF, Slater P, Simpson MD, et al. Frontal cortical and left temporal glutamatergic dysfunction in schizophrenia. J Neurochem. 1989;52:1781-1786.
    • (1989) J Neurochem , vol.52 , pp. 1781-1786
    • Deakin, J.F.1    Slater, P.2    Simpson, M.D.3
  • 95
    • 0032819210 scopus 로고    scopus 로고
    • Lamina-specific alterations in the dopamine innervation of the prefrontal cortex in schizophrenic subjects
    • Akil M, Pierri JN, Whitehead RE, et al. Lamina-specific alterations in the dopamine innervation of the prefrontal cortex in schizophrenic subjects. Am J Psychiatry. 1999;156:1580-1589.
    • (1999) Am J Psychiatry , vol.156 , pp. 1580-1589
    • Akil, M.1    Pierri, J.N.2    Whitehead, R.E.3
  • 96
    • 0036327663 scopus 로고    scopus 로고
    • Evidence for decreased DARPP-32 in the prefrontal cortex of patients with schizophrenia
    • Albert KA, Hemmings HC, Jr, Adamo AI, et al. Evidence for decreased DARPP-32 in the prefrontal cortex of patients with schizophrenia. Arch Gen Psychiatry. 2002;59:705-712.
    • (2002) Arch Gen Psychiatry , vol.59 , pp. 705-712
    • Albert, K.A.1    Hemmings Jr., H.C.2    Adamo, A.I.3
  • 97
    • 0028875197 scopus 로고
    • Abnormal excitatory neurotransmitter metabolism in schizophrenic brains
    • Tsai G, Passani LA, Slusher BS, et al. Abnormal excitatory neurotransmitter metabolism in schizophrenic brains. Arch Gen Psychiatry. 1995;52:829-836.
    • (1995) Arch Gen Psychiatry , vol.52 , pp. 829-836
    • Tsai, G.1    Passani, L.A.2    Slusher, B.S.3
  • 98
    • 0033844601 scopus 로고    scopus 로고
    • Regulation of neurotransmitter release by metabotropic glutamate receptors
    • Cartmell J, Schoepp DD. Regulation of neurotransmitter release by metabotropic glutamate receptors. J Neurochem. 2000;75:889-907.
    • (2000) J Neurochem , vol.75 , pp. 889-907
    • Cartmell, J.1    Schoepp, D.D.2
  • 99
    • 0032967531 scopus 로고    scopus 로고
    • The reduced neuropil hypothesis: A circuit-based model of schizophrenia
    • Selemon LD, Goldman-Rakic PS. The reduced neuropil hypothesis: a circuit-based model of schizophrenia. Biol Psychiatry. 1999;45:17-25.
    • (1999) Biol Psychiatry , vol.45 , pp. 17-25
    • Selemon, L.D.1    Goldman-Rakic, P.S.2
  • 100
    • 0038433234 scopus 로고    scopus 로고
    • Association of the G1947A COMT (Val(108/158)Met) gene polymorphism with prefrontal P300 during information processing
    • Gallinat J, Bajbouj M, Sander T, et al. Association of the G1947A COMT (Val(108/158)Met) gene polymorphism with prefrontal P300 during information processing. Biol Psychiatry. 2003;54:40-48.
    • (2003) Biol Psychiatry , vol.54 , pp. 40-48
    • Gallinat, J.1    Bajbouj, M.2    Sander, T.3
  • 101
    • 6044246071 scopus 로고    scopus 로고
    • Variants in the catechol-O-methyltransferase (COMT) gene are associated with schizophrenia in Irish high-density families
    • Chen X, Wang X, O'Neill AF, Walsh D, Kendler KS. Variants in the catechol-O-methyltransferase (COMT) gene are associated with schizophrenia in Irish high-density families. Mol Psychiatry. 2004;9:962-967.
    • (2004) Mol Psychiatry , vol.9 , pp. 962-967
    • Chen, X.1    Wang, X.2    O'Neill, A.F.3    Walsh, D.4    Kendler, K.S.5
  • 102
    • 0037365978 scopus 로고    scopus 로고
    • Association between a functional catechol O-methyltransferase gene polymorphism and schizophrenia: Metaanalysis of case-control and family-based studies
    • Glatt SJ, Faraone SV, Tsuang MT. Association between a functional catechol O-methyltransferase gene polymorphism and schizophrenia: metaanalysis of case-control and family-based studies. Am J Psychiatry. 2003;160:469-476.
    • (2003) Am J Psychiatry , vol.160 , pp. 469-476
    • Glatt, S.J.1    Faraone, S.V.2    Tsuang, M.T.3
  • 103
    • 0033569736 scopus 로고    scopus 로고
    • Linkage disequilibrium on the COMT gene in French schizophrenics and controls
    • de Chaldée M, Laurent C, Thibaut F, et al. Linkage disequilibrium on the COMT gene in French schizophrenics and controls. Am J Med Genet. 1999;88:452-457.
    • (1999) Am J Med Genet , vol.88 , pp. 452-457
    • Chaldée, M.1    Laurent, C.2    Thibaut, F.3
  • 104
    • 0038810014 scopus 로고    scopus 로고
    • Expression and functional role of mGluR3 and mGluRS in human astrocytes and glioma cells: Opposite regulation of glutamate transporter proteins
    • Aronica E, Gorter JA, Ijlst-Keizers H, et al. Expression and functional role of mGluR3 and mGluRS in human astrocytes and glioma cells: opposite regulation of glutamate transporter proteins. Eur J Neurosci. 2003;17:2106-2118.
    • (2003) Eur J Neurosci , vol.17 , pp. 2106-2118
    • Aronica, E.1    Gorter, J.A.2    Ijlst-Keizers, H.3
  • 105
    • 13344286293 scopus 로고    scopus 로고
    • Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate
    • Rothstein JD, Dykes-Hoberg M, Pardo CA, et al. Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate. Neuron. 1996;16:675-686.
    • (1996) Neuron , vol.16 , pp. 675-686
    • Rothstein, J.D.1    Dykes-Hoberg, M.2    Pardo, C.A.3
  • 106
    • 38149138747 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor 3 (GRM3) gene variation is not associated with schizophrenia or bipolar affective disorder in the German population
    • Marti SB, Cichon S, Propping P, Nöthen M. Metabotropic glutamate receptor 3 (GRM3) gene variation is not associated with schizophrenia or bipolar affective disorder in the German population. Am J Med Genet. 2002;114:46-50.
    • (2002) Am J Med Genet , vol.114 , pp. 46-50
    • Marti, S.B.1    Cichon, S.2    Propping, P.3    Nöthen, M.4
  • 107
    • 12444314603 scopus 로고    scopus 로고
    • Positive associations of polymorphisms in the metabotropic glutamate receptor type 3 gene (GRM3) with schizophrenia
    • Fujii Y, Shibata H, Kikuta R, et al. Positive associations of polymorphisms in the metabotropic glutamate receptor type 3 gene (GRM3) with schizophrenia. Psychiatr Genet 2003;13:71-76.
    • (2003) Psychiatr Genet , vol.13 , pp. 71-76
    • Fujii, Y.1    Shibata, H.2    Kikuta, R.3
  • 108
    • 0032078391 scopus 로고    scopus 로고
    • Expression of the human excitatory amino acid transporter 2 and metabotropic glutamate receptors 3 and 5 in the prefrontal cortex from normal individuals and patients with schizophrenia
    • Ohnuma T, Augood SJ, Arai H, McKenna PJ, Emson PC. Expression of the human excitatory amino acid transporter 2 and metabotropic glutamate receptors 3 and 5 in the prefrontal cortex from normal individuals and patients with schizophrenia. Brain Res Mol Brain Res. 1998;56:207-217.
    • (1998) Brain Res Mol Brain Res , vol.56 , pp. 207-217
    • Ohnuma, T.1    Augood, S.J.2    Arai, H.3    McKenna, P.J.4    Emson, P.C.5
  • 109
    • 0034068655 scopus 로고    scopus 로고
    • Attenuation of specific PCP-evoked behaviors by the potent mGlu2/3 receptor agonist, LY379268 and comparison with the atypical antipsychotic, clozapine
    • Cartmell J, Monn JA, Schoepp DD. Attenuation of specific PCP-evoked behaviors by the potent mGlu2/3 receptor agonist, LY379268 and comparison with the atypical antipsychotic, clozapine. Psychopharmacology (Berl). 2000;148:423-429.
    • (2000) Psychopharmacology (Berl) , vol.148 , pp. 423-429
    • Cartmell, J.1    Monn, J.A.2    Schoepp, D.D.3
  • 110
    • 0032575715 scopus 로고    scopus 로고
    • Reversal of phencyclidine effects by a group II metabotropic glutamate receptor agonist in rats
    • Moghaddam B, Adams BW. Reversal of phencyclidine effects by a group II metabotropic glutamate receptor agonist in rats. Science. 1998;281:1349-1352.
    • (1998) Science , vol.281 , pp. 1349-1352
    • Moghaddam, B.1    Adams, B.W.2
  • 111
    • 0030044865 scopus 로고    scopus 로고
    • Localization of two metabotropic glutamate receptor genes, GRM3 and GRM8, to human chromosome 7q
    • Scherer SW, Duvoisin RM, Kuhn R, Heng HH, Belloni E, Tsui LC. Localization of two metabotropic glutamate receptor genes, GRM3 and GRM8, to human chromosome 7q. Genomics. 1996;31:230-233.
    • (1996) Genomics , vol.31 , pp. 230-233
    • Scherer, S.W.1    Duvoisin, R.M.2    Kuhn, R.3    Heng, H.H.4    Belloni, E.5    Tsui, L.C.6
  • 112
    • 0037219325 scopus 로고    scopus 로고
    • Prefrontal-posterior parietal networks in schizophrenia: Primary dysfunctions and secondary compensations
    • Quintana J, Wong T, Ortiz-Portillo E, et al. Prefrontal-posterior parietal networks in schizophrenia: primary dysfunctions and secondary compensations. Biol Psychiatry. 2003;53:12-24.
    • (2003) Biol Psychiatry , vol.53 , pp. 12-24
    • Quintana, J.1    Wong, T.2    Ortiz-Portillo, E.3
  • 113
    • 9644291602 scopus 로고    scopus 로고
    • A case-control study of the relationship between the metabotropic glutamate receptor 3 gene and schizophrenia in the Chinese population
    • Chen Q, He G, Chen Q, et al. A case-control study of the relationship between the metabotropic glutamate receptor 3 gene and schizophrenia in the Chinese population. Schizophr Res. 2005;73:21-26.
    • (2005) Schizophr Res , vol.73 , pp. 21-26
    • Chen, Q.1    He, G.2    Chen, Q.3
  • 114
    • 2342550552 scopus 로고    scopus 로고
    • Variant brain-derived neurotrophic factor (BDNF) (Met66) alters the intracellular trafficking and activity-dependent secretion of wild-type BDNF in neurosecretory cells and cortical neurons
    • Chen ZY, Patel PD, Sant G, et al. Variant brain-derived neurotrophic factor (BDNF) (Met66) alters the intracellular trafficking and activity-dependent secretion of wild-type BDNF in neurosecretory cells and cortical neurons. J Neurosci. 2004;24:4401-4411.
    • (2004) J Neurosci , vol.24 , pp. 4401-4411
    • Chen, Z.Y.1    Patel, P.D.2    Sant, G.3
  • 115
    • 0027319085 scopus 로고
    • Brain morphology, dopamine, and eye-tracking abnormalities in first-episode schizophrenia. Prevalence and clinical correlates
    • Lieberman JA, Jody D, Alvir JM, et al. Brain morphology, dopamine, and eye-tracking abnormalities in first-episode schizophrenia. Prevalence and clinical correlates. Arch Gen Psychiatry. 1993;50:357-368.
    • (1993) Arch Gen Psychiatry , vol.50 , pp. 357-368
    • Lieberman, J.A.1    Jody, D.2    Alvir, J.M.3
  • 116
    • 0038474162 scopus 로고    scopus 로고
    • Deficits in gain of smooth pursuit eye movements in schizophrenia and affective disorder patients and their unaffected relatives
    • Kathmann N, Hochrein A, Uwer R, Bondy B. Deficits in gain of smooth pursuit eye movements in schizophrenia and affective disorder patients and their unaffected relatives. Am J Psychiatry. 2003;160:696-702.
    • (2003) Am J Psychiatry , vol.160 , pp. 696-702
    • Kathmann, N.1    Hochrein, A.2    Uwer, R.3    Bondy, B.4
  • 117
    • 0025213410 scopus 로고
    • Sensory gating in normals and schizophrenics: A failure to find strong P50 suppression in normals
    • Kathmann N, Engel RR. Sensory gating in normals and schizophrenics: a failure to find strong P50 suppression in normals. Biol Psychiatry. 1990;27:1216-1226.
    • (1990) Biol Psychiatry , vol.27 , pp. 1216-1226
    • Kathmann, N.1    Engel, R.R.2
  • 118
    • 0345708059 scopus 로고    scopus 로고
    • Interpreting abnormality: An EEG and MEG study of P50 and the auditory paired-stimulus paradigm
    • Edgar JC, Huang MX, Weisend MP, et al. Interpreting abnormality: an EEG and MEG study of P50 and the auditory paired-stimulus paradigm. Biol Psychol. 2003;65:1-20.
    • (2003) Biol Psychol , vol.65 , pp. 1-20
    • Edgar, J.C.1    Huang, M.X.2    Weisend, M.P.3
  • 119
    • 0033822176 scopus 로고    scopus 로고
    • Neurophysiological measures of working memory and individual differences in cognitive ability and cognitive style
    • Gevins A, Smith ME. Neurophysiological measures of working memory and individual differences in cognitive ability and cognitive style. Cereb Cortex. 2000;10:829-839.
    • (2000) Cereb Cortex , vol.10 , pp. 829-839
    • Gevins, A.1    Smith, M.E.2
  • 121
    • 7544237708 scopus 로고    scopus 로고
    • NIMH-MATRICS survey on assessment of neurocognition in schizophrenia
    • Kern RS, Green MF, Nuechterlein KH, Deng BH. NIMH-MATRICS survey on assessment of neurocognition in schizophrenia. Schizophr Res. 2004;72:11-19.
    • (2004) Schizophr Res , vol.72 , pp. 11-19
    • Kern, R.S.1    Green, M.F.2    Nuechterlein, K.H.3    Deng, B.H.4
  • 122
    • 2342526545 scopus 로고    scopus 로고
    • Cognitive functioning in schizophrenia: A consensus statement on its role in the definition and evaluation of effective treatments for the illness
    • Harvey PD, Green MF, Keefe RS, Velligan DI. Cognitive functioning in schizophrenia: a consensus statement on its role in the definition and evaluation of effective treatments for the illness. J Clin Psychiatry. 2004;65:361-372.
    • (2004) J Clin Psychiatry , vol.65 , pp. 361-372
    • Harvey, P.D.1    Green, M.F.2    Keefe, R.S.3    Velligan, D.I.4
  • 123
    • 4444220908 scopus 로고    scopus 로고
    • Approaching a consensus cognitive battery for clinical trials in schizophrenia: The NIMH-MATRICS conference to select cognitive domains and test criteria
    • Green MF, Nuechterlein KH, Gold JM, et al. Approaching a consensus cognitive battery for clinical trials in schizophrenia: the NIMH-MATRICS conference to select cognitive domains and test criteria. Biol Psychiatry. 2004;56:301-307.
    • (2004) Biol Psychiatry , vol.56 , pp. 301-307
    • Green, M.F.1    Nuechterlein, K.H.2    Gold, J.M.3


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