The cytolethal distending toxin subunit CdtB of Helicobacter hepaticus promotes senescence and endoreplication in xenograft mouse models of hepatic and intestinal cell lines

Frontiers in Cellular and Infection Microbiology

Volumn 7, Issue JUN, 2017, Pages

  Péré Védrenne, Christelle ^a,b   Prochazkova Carlotti, Martina ^a,b   Rousseau, Benoit ^b   He, Wencan ^a,b   Chambonnier, Lucie ^a,b   Sifré, Elodie ^a,b   Buissonnière, Alice ^a,b   Dubus, Pierre ^a,b,c   Mégraud, Francis ^a,b   Varon, Christine ^a,b   Ménard, Armelle ^a,b  

^a INSERM   (France)

^b UNIVERSITÉ DE BORDEAUX   (France)

^c BORDEAUX UNIVERSITY HOSPITAL   (France)

Author keywords

Apoptosis; Cytolethal distending toxin; Endoreplication; Helicobacter hepaticus; Mitosis; Senescence

Indexed keywords

CYTOKERATIN; CYTOLETHAL DISTENDING TOXIN; CYTOLETHAL DISTENDING TOXIN SUBUNIT CDTB; KI 67 ANTIGEN; PROTEIN P21; UNCLASSIFIED DRUG; BACTERIAL TOXIN; DOXYCYCLINE; GAMMA-H2AX PROTEIN, MOUSE; HISTONE; MKI67 PROTEIN, MOUSE; PHOTOPROTEIN; RED FLUORESCENT PROTEIN;

AGGRESSIVENESS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CATALYSIS; CELL CYCLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOSKELETON; ENDOREDUPLICATION; FLUORESCENCE IN SITU HYBRIDIZATION; GENE MUTATION; GENE OVEREXPRESSION; GENETIC TRANSDUCTION; HELICOBACTER HEPATICUS; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; INTESTINE CELL; LENTIVIRAL TRANSDUCTION; LIVER CELL LINE; MITOSIS; MOUSE; NONHUMAN; PLOIDY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENESCENCE; TRANSGENE; TUMOR GROWTH; TUMOR VOLUME; XENOGRAFT; AGING; ANIMAL; CONGENITAL CORNEA DYSTROPHY; DRUG EFFECTS; EPITHELIUM CELL; HT-29 CELL LINE; INTESTINE; LIVER; METABOLISM; MICROFLORA; TUMOR CELL LINE;

AGING; ANIMALS; APOPTOSIS; BACTERIAL TOXINS; CELL CYCLE; CELL LINE, TUMOR; CORNEAL DYSTROPHIES, HEREDITARY; CYTOSKELETON; DOXYCYCLINE; ENDOREDUPLICATION; EPITHELIAL CELLS; HELICOBACTER HEPATICUS; HETEROGRAFTS; HISTONES; HT29 CELLS; HUMANS; INTESTINES; KI-67 ANTIGEN; LIVER; LUMINESCENT PROTEINS; MICE; MICROBIOTA;

EID: 85027490834     PISSN: None     EISSN: 22352988     Source Type: Journal    
DOI: 10.3389/fcimb.2017.00268     Document Type: Article

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