Expression and activity of the cytolethal distending toxin of Helicobacter hepaticus

Biochemical and Biophysical Research Communications

Volumn 318, Issue 3, 2004, Pages 739-745

  Avenaud, Philippe ^a   Castroviejo, Michel ^a   Claret, Sandra ^a   Rosenbaum, Jean ^b   Mégraud, Francis ^a   Ménard, Armelle ^a  

^a UNIVERSITÉ DE BORDEAUX   (France)

^b INSERM   (France)

Author keywords

Cytolethal distending toxin; DNase I; Helicobacter hepaticus; Phosphatase

Indexed keywords

CYTOLETHAL DISTENDING TOXIN A; CYTOLETHAL DISTENDING TOXIN B; CYTOLETHAL DISTENDING TOXIN C; DEOXYRIBONUCLEASE; HISTIDINE; MUTANT PROTEIN; PROTEIN SUBUNIT; RECOMBINANT PROTEIN; TOXIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CYTOTOXICITY; HELICOBACTER HEPATICUS; IN VITRO STUDY; MOLECULAR MECHANICS; MOUSE; MUTATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

HELICOBACTER; HELICOBACTER HEPATICUS;

EID: 2442420080     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.04.089     Document Type: Article

References (31)

1. Fox J.G., Dewhirst F.E., Tully J.G., Paster B.J., Yan L., Taylor N.S., Collins M.J., Gorelick P.L., Ward J.M. Helicobacter hepaticus sp. nov., a microaerophilic bacterium isolated from livers and intestinal mucosal scrapings from mice. J. Clin. Microbiol. 32:1994;1238-1245
2. Young V.B., Knox K.A., Schauer D.B. Cytolethal distending toxin sequence and activity in the enterohepatic pathogen Helicobacter hepaticus. Infect. Immun. 68:2000;184-191
3. Pickett C.L., Cottle D.L., Pesci E.C., Bikah G. Cloning, sequencing, and expression of the Escherichia coli cytolethal distending toxin genes. Infect. Immun. 62:1994;1046-1051
4. Scott D.A., Kaper J.B. Cloning and sequencing of the genes encoding Escherichia coli cytolethal distending toxin. Infect. Immun. 62:1994;244-251
5. Johnson W.M., Lio H. Production of shiga toxin and a cytolethal distending toxin (CLDT) by serogroups of Shigella spp. FEMS Microbiol. Lett. 48:1987;235-238
6. Okuda J., Kurazono H., Takeda Y. Distribution of the cytolethal distending toxin A gene (cdtA) among species of Shigella and Vibrio, and cloning and sequencing of the cdt gene from Shigella dysenteriae. Microb. Pathog. 18:1995;167-172
7. Pickett C.L., Pesci E.C., Cottle D.L., Russell G., Erdem A.N., Zeytin H. Prevalence of cytolethal distending toxin production in Campylobacter jejuni and relatedness of Campylobacter sp. cdtB genes. Infect. Immun. 64:1996;2070-2078
8. Sugai M., Kawamoto T., Peres S.Y., Ueno Y., Komatsuzawa H., Fujiwara T., Kurihara H., Suginaka H., Oswald E. The cell cycle-specific growth-inhibitory factor produced by Actinobacillus actinomycetemcomitans is a cytolethal distending toxin. Infect. Immun. 66:1998;5008-5019
9. Cope L.D., Lumbley S., Latimer J.L., Klesney-Tait J., Stevens M.K., Johnson L.S., Purven M., Munson R.S. Jr., Lagergard T., Radolf J.D., et al. A diffusible cytotoxin of Haemophilus ducreyi. Proc. Natl. Acad. Sci. USA. 94:1997;4056-4061
10. Chien C.C., Taylor N.S., Ge Z.M., Schauer D.B., Young V.B., Fox J.G. Identification of cdtB homologues and cytolethal distending toxin activity in enterohepatic Helicobacter spp. J. Med. Microbiol. 49:2000;525-534
11. Pickett C.L., Whitehouse C.A. The cytolethal distending toxin family. Trends. Microbiol. 7:1999;292-297
12. Escalas N., Davezac N., De Rycke J., Baldin V., Mazars R., Ducommun B. Study of the cytolethal distending toxin-induced cell cycle arrest in HeLa cells: involvement of the CDC25 phosphatase. Exp. Cell Res. 257:2000;206-212
13. Lara Tejero M., Galan J.E. CdtA, CdtB, and CdtC form a tripartite complex that is required for cytolethal distending toxin activity. Infect. Immun. 69:2001;4358-4365
14. Mayer M.P., Bueno L.C., Hansen E.J., DiRienzo J.M. Identification of a cytolethal distending toxin gene locus and features of a virulence-associated region in Actinobacillus actinomycetemcomitans. Infect. Immun. 67:1999;1227-1237
15. Lara-Tejero M., Galan J.E. A bacterial toxin that controls cell cycle progression as a deoxyribonuclease I-like protein. Science. 290:2000;354-357
16. Elwell C.A., Dreyfus L.A. DNase I homologous residues in CdtB are critical for cytolethal distending toxin-mediated cell cycle arrest. Mol. Microbiol. 37:2000;952-963
17. Elwell C., Chao K.L., Patel K., Dreyfus L. Escherichia coli CdtB mediates cytolethal distending toxin cell cycle arrest. Infect. Immun. 69:2001;3418-3422
18. 2+-dependent endonucleases. Trends Biochem. Sci. 25:2000;272-273
19. Dlakic M. Is CdtB a nuclease or a phosphatase? Science. 291:2001;547
20. Ge Z., White D.A., Whary M.T., Fox J.G. Fluorogenic PCR-based quantitative detection of a murine pathogen, Helicobacter hepaticus. J. Clin. Microbiol. 39:2001;2598-2602
21. Sambrook J., Fritsch E.F., Maniatis T. second ed. Molecular Cloning. vol. 3:1989;Cold Spring Harbor Laboratory Press, USA
22. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods. 65:1983;55-63
23. Pan C.Q., Ulmer J.S., Herzka A., Lazarus R.A. Mutational analysis of human DNase I at the DNA binding interface: implications for DNA recognition, catalysis, and metal ion dependence. Protein Sci. 7:1998;628-636
24. Tsujishita Y., Guo S., Stolz L.E., York J.D., Hurley J.H. Specificity determinants in phosphoinositide dephosphorylation: crystal structure of an archetypal inositol polyphosphate 5-phosphatase. Cell. 105:2001;379-389
25. Taylor N.S., Fox J.G., Yan L. In-vitro hepatotoxic factor in Helicobacter hepaticus, H. pylori and other Helicobacter species. J. Med. Microbiol. 42:1995;48-52
26. Lara-Tejero M., Galan J.E. Cytolethal distending toxin: limited damage as a strategy to modulate cellular functions. Trends Microbiol. 10:2002;147-152
27. Nilsson H.O., Castedal M., Olsson R., Wadström T. Detection of Helicobacter in the liver of patients with chronic cholestatic liver diseases. J. Physiol. Pharmacol. 50:1999;875-882
28. Nilsson H.O., Taneera J., Castedal M., Glatz E., Olsson R., Wadström T. Identification of Helicobacter pylori and other Helicobacter species by PCR, hybridization, and partial DNA sequencing in human liver samples from patients with primary sclerosing cholangitis or primary biliary cirrhosis. J. Clin. Microbiol. 38:2000;1072-1076
29. Avenaud P., Marais A., Monteiro L., Le Bail B., Bioulac Sage P., Balabaud C., Megraud F. Detection of Helicobacter species in the liver of patients with and without primary liver carcinoma. Cancer. 89:2000;1431-1439
30. Nilsson H.O., Mulchandani R., Stenram U., Wadstrom T. Helicobacter species identified in liver from patients with cholangiocarcinoma and hepatocellular carcinoma. Gastroenterology. 120:2001;323-324
31. Gorman M.A., Morera S., Rothwell D.G., de La Fortelle E., Mol C.D., Tainer J.A., Hickson I.D., Freemont P.S. The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA abasic sites. EMBO J. 16:1997;6548-6558