In vivo silencing of Reptin blocks the progression of human hepatocellular carcinoma in xenografts and is associated with replicative senescence

Journal of Hepatology

Volumn 52, Issue 5, 2010, Pages 681-689

  Ménard, Ludovic ^a   Taras, Danièle ^a   Grigoletto, Aude ^a   Haurie, Valérie ^a   Nicou, Alexandra ^a   Dugot Senant, Nathalie ^a   Costet, Pierre ^a   Rousseau, Benoît ^a   Rosenbaum, Jean ^a,b  

^a UNIVERSITÉ DE BORDEAUX   (France)

^b BORDEAUX UNIVERSITY HOSPITAL   (France)

Author keywords

Apoptosis; Doxycycline; Liver cancer; Reptin; Senescence; shRNA

Indexed keywords

ADENOSINE TRIPHOSPHATASE; DOXYCYCLINE; FIREFLY LUCIFERASE; REPTIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL AGING; CONTROLLED STUDY; DRUG TARGETING; GENE SILENCING; HETEROCHROMATIN; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; TUMOR XENOGRAFT;

ANIMALS; APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CARRIER PROTEINS; CELL AGING; CELL DIVISION; CELL LINE, TUMOR; DNA HELICASES; DNA PRIMERS; DOXYCYCLINE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; GENES, REPORTER; HUMANS; LIVER NEOPLASMS; LUCIFERASES; MICE; MICE, INBRED NOD; MICE, SCID; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, NEOPLASM; RNA, SMALL INTERFERING; TRANSPLANTATION, HETEROLOGOUS;

EID: 77951623749     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2009.12.029     Document Type: Article

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