A Sensitized IGF1 Treatment Restores Corticospinal Axon-Dependent Functions

Neuron

Volumn 95, Issue 4, 2017, Pages 817-833.e4

  Liu, Yuanyuan ^a,b   Wang, Xuhua ^a,b   Li, Wenlei ^a,b,c   Zhang, Qian ^a,b,d   Li, Yi ^a,b   Zhang, Zicong ^a,b   Zhu, Junjie ^a,b   Chen, Bo ^a,b   Williams, Philip R ^a,b   Zhang, Yiming ^a,b   Yu, Bin ^d   Gu, Xiaosong ^e   He, Zhigang ^a,b  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c AFFILIATED HOSPITAL OF NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

^d FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^e NANTONG UNIVERSITY   (China)

Author keywords

4 aminopyridine; axon regeneration; axon sprouting; IGF1; ischemic stroke; osteopontin; spinal cord injury

Indexed keywords

4-AMINOPYRIDINE METHIODIDE; AMINOPYRIDINE DERIVATIVE; OSTEOPONTIN; SEROTONIN; SOMATOMEDIN C;

AGE; ANIMAL; AXOTOMY; CONVALESCENCE; DISEASE MODEL; DRUG EFFECTS; GENETICS; HEMISPHERIC DOMINANCE; HINDLIMB; METABOLISM; MOUSE; MOVEMENT DISORDERS; NERVE CELL; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PSYCHOMOTOR PERFORMANCE; PYRAMIDAL TRACT; REFLEX; SPINAL CORD INJURIES; STROKE; TIME FACTOR;

AGE FACTORS; AMINOPYRIDINES; ANIMALS; AXOTOMY; DISEASE MODELS, ANIMAL; FUNCTIONAL LATERALITY; HINDLIMB; INSULIN-LIKE GROWTH FACTOR I; MICE; MOVEMENT DISORDERS; NEURONS; OSTEOPONTIN; PSYCHOMOTOR PERFORMANCE; PYRAMIDAL TRACTS; RECOVERY OF FUNCTION; REFLEX; SEROTONIN; SPINAL CORD INJURIES; STROKE; TIME FACTORS;

EID: 85027457606     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2017.07.037     Document Type: Article

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