Novel potassium channel blocker, 4-AP-3-MeOH, inhibits fast potassium channels and restores axonal conduction in injured guinea pig spinal cord white matter

Journal of Neurophysiology

Volumn 103, Issue 1, 2010, Pages 469-478

  Sun, Wenjing ^a   Smith, Daniel ^c   Fu, Yan ^b   Cheng, Ji Xin ^b   Bryn, Steven ^c   Borgens, Richard ^a,b   Shi, Riyi ^a,b  

^a PURDUE UNIVERSITY   (United States)

^b PURDUE UNIVERSITY   (United States)

^c PURDUE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOPYRIDINE; 4 AMINOPYRIDINE 3 METHANOL; 4 AP 3 MEOH; AMINOPYRIDINE DERIVATIVE; IA ANTIBODY; METHANOL; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; UNCLASSIFIED DRUG;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DORSAL ROOT; GLIA CELL; GUINEA PIG; NERVE BLOCK; NERVE CONDUCTION; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; SPINAL CORD; SPINAL CORD INJURY; SPINE INJURY; WHITE MATTER;

AMINOPYRIDINES; ANIMALS; AXONS; CELLS, CULTURED; FEMALE; GANGLIA, SPINAL; GUINEA PIGS; KV1.2 POTASSIUM CHANNEL; MEMBRANE POTENTIALS; NERVE FIBERS, MYELINATED; NEURAL CONDUCTION; NEURONS; NEUROPROTECTIVE AGENTS; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNEL BLOCKERS; SPINAL CORD INJURIES;

EID: 74049158590     PISSN: 00223077     EISSN: 15221598     Source Type: Journal    
DOI: 10.1152/jn.00154.2009     Document Type: Article

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