Asynchronous therapy restores motor control by rewiring of the rat corticospinal tract after stroke

Science

Volumn 344, Issue 6189, 2014, Pages 1250-1255

  Wahl, A S ^a,b   Omlor, W ^b   Rubio, J C ^c   Chen, J L ^b   Zheng, H ^c   Schroter A ^a   Gullo, M ^a,b   Weinmann, O ^a,b   Kobayashi, K ^d   Helmchen, F ^b   Ommer, B ^c   Schwab, M E ^a,b  

^a ETH ZURICH   (Switzerland)

^b University of Zurich Brain Research Institute   (Switzerland)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d NATIONAL INSTITUTE FOR PHYSIOLOGICAL SCIENCES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DOXYCYCLINE; GROWTH PROMOTOR; MYELIN PROTEIN; PROTEIN NOGO;

BRAIN; PROTEIN; RODENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CERVICAL SPINAL CORD; CONTROLLED STUDY; ELECTROMYOGRAM; EXPERIMENTAL STROKE; FORELIMB; GENE TRANSFER; GRAY MATTER; IMMUNOTHERAPY; INTERNEURON; MOTOR CONTROL; NERVE FIBER GROWTH; NEUROIMAGING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PATTERN RECOGNITION; PHARMACOGENETICS; PRIORITY JOURNAL; PYRAMIDAL TRACT; RAT; REHABILITATION MEDICINE; REINNERVATION; TRAINING; TRANSGENE; ANIMAL; CEREBROVASCULAR ACCIDENT; CONVALESCENCE; DRUG ANTAGONISM; FEMALE; FOREBRAIN; INJURY; LONG EVANS RAT; METHODOLOGY; MOTOR CORTEX; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; FEMALE; IMMUNOTHERAPY; MOTOR CORTEX; MYELIN PROTEINS; PHYSICAL CONDITIONING, ANIMAL; PROSENCEPHALON; PYRAMIDAL TRACTS; RATS; RATS, LONG-EVANS; RECOVERY OF FUNCTION; STROKE;

EID: 84902590437     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1253050     Document Type: Article

References (23)

1. T. H. Murphy, D. Corbett, Nat. Rev. Neurosci. 10, 861-872 (2009).
2. M. A. Dimyan, L. G. Cohen, Nat. Rev. Neurol. 7, 76-85 (2011).
3. P. Langhorne, J. Bernhardt, G. Kwakkel, Lancet 377, 1693-1702 (2011).
4. S. T. Carmichael, Ann. Neurol. 59, 735-742 (2006).
5. S. R. Zeiler, J. W. Krakauer, Curr. Opin. Neurol. 26, 609-616 (2013).
6. N. T. Lindau et al., Brain 137, 739-756 (2014).
7. T. Oertle et al., J. Neurosci. 23, 5393-5406 (2003).
8. M. Kinoshita et al., Nature 487, 235-238 (2012).
9. B. R. Conklin et al., Nat. Methods 5, 673-678 (2008).
10. G. M. Alexander et al., Neuron 63, 27-39 (2009).
11. S. M. Ferguson et al., Nat. Neurosci. 14, 22-24 (2011).
12. B. Ommer, T. Mader, J. M. Buhmann, Int. J. Comput. Vis. 83, 57-71 (2009).
13. D. L. Adkins, T. A. Jones, Neurosci. Lett. 380, 214-218 (2005).
14. M. Alaverdashvili, A. Foroud, D. H. Lim, I. Q. Whishaw, Behav. Brain Res. 188, 281-290 (2008).
15. M. L. Starkey, C. Bleul, I. C. Maier, M. E. Schwab, Exp. Neurol. 232, 81-89 (2011).
16. S. Y. Tsai et al., Exp. Brain Res. 182, 261-266 (2007).
17. G. García-Alías, S. Barkhuysen, M. Buckle, J. W. Fawcett, Nat. Neurosci. 12, 1145-1151 (2009).
18. C. Wiessner et al., J. Cereb. Blood Flow Metab. 23, 154-165 (2003).
19. I. C. Maier et al., J. Neurosci. 28, 9386-9403 (2008).
20. C. O. Asante, J. H. Martin, PLOS ONE 8, e74454 (2013).
21. E. Azim, J. Jiang, B. Alstermark, T. M. Jessell, Nature 508, 357-363 (2014).
22. J. C. Petruska et al., J. Neurosci. 27, 4460-4471 (2007).
23. J. W. Krakauer, S. T. Carmichael, D. Corbett, G. F. Wittenberg, Neurorehabil. Neural Repair 26, 923-931 (2012).