Overexpression of Sox11 promotes corticospinal tract regeneration after spinal injury while interfering with functional recovery

Journal of Neuroscience

Volumn 35, Issue 7, 2015, Pages 3139-3145

  Wang, Zimei ^a   Reynolds, Ashley ^a   Kirry, Adam ^a   Nienhaus, Christopher ^a   Blackmore, Murray G ^a  

^a MARQUETTE UNIVERSITY   (United States)

Author keywords

Axon regeneration; Gene therapy; Sox11; Spinal cord injury; Transcription factor

Indexed keywords

TRANSCRIPTION FACTOR SOX11; PHOTOPROTEIN; SOX11 PROTEIN, MOUSE; TRANSCRIPTION FACTOR SOX;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CONVALESCENCE; EXPERIMENTAL BEHAVIORAL TEST; FEMALE; FORELIMB; IMMUNOHISTOCHEMISTRY; MOLECULAR CLONING; MOUSE; NERVE FIBER GROWTH; NERVE REGENERATION; NERVE SPROUTING; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYRAMIDAL TRACT; SPINAL GANGLION; SPINE INJURY; VIRUS EXPRESSION; ZEBRA FISH; ADENOVIRIDAE; ANIMAL; C57BL MOUSE; DISEASE MODEL; EXPLORATORY BEHAVIOR; GENE EXPRESSION REGULATION; GENETICS; HAND STRENGTH; METABOLISM; NERVE CELL; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PSYCHOMOTOR PERFORMANCE; SPINAL CORD INJURY; TRANSGENIC MOUSE;

ADENOVIRIDAE; ANIMALS; DISEASE MODELS, ANIMAL; EXPLORATORY BEHAVIOR; FEMALE; GANGLIA, SPINAL; GENE EXPRESSION REGULATION; HAND STRENGTH; LUMINESCENT PROTEINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NERVE REGENERATION; NEURONS; PSYCHOMOTOR PERFORMANCE; PYRAMIDAL TRACTS; RECOVERY OF FUNCTION; SOXC TRANSCRIPTION FACTORS; SPINAL CORD INJURIES;

EID: 84923040472     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2832-14.2015     Document Type: Article

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