Nlrp6- and ASC-Dependent Inflammasomes Do Not Shape the Commensal Gut Microbiota Composition

Immunity

Volumn 47, Issue 2, 2017, Pages 339-348.e4

  Mamantopoulos, Michail ^a,b   Ronchi, Francesca ^c   Van Hauwermeiren, Filip ^a,b   Vieira Silva, Sara ^b,d   Yilmaz, Bahtiyar ^c   Martens, Liesbet ^a,b   Saeys, Yvan ^a,b   Drexler, Stefan K ^e   Yazdi, Amir S ^f   Raes, Jeroen ^b,d   Lamkanfi, Mohamed ^a,b   McCoy, Kathy D ^c,g   Wullaert, Andy ^a,b  

^a GHENT UNIVERSITY   (Belgium)

^b DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^c UNIVERSITY OF BERN   (Switzerland)

^d REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^e UNIVERSITY OF BASEL   (Switzerland)

^f UNIVERSITY OF TÜBINGEN   (Germany)

^g UNIVERSITY OF CALGARY   (Canada)

Author keywords

16S sequencing; ASC; caspase 1; DSS colitis; dysbiosis; gut microbiota; inflammasomes; innate immunity; interleukin; Nlrp6

Indexed keywords

DEXTRAN SULFATE; INFLAMMASOME; PROTEIN ASC; PROTEIN NLRP6; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; CELL SURFACE RECEPTOR; DODECYL SULFATE SODIUM; NOD-LIKE RECEPTOR PYRIN DOMAIN-CONTAINING PROTEIN 6, MOUSE; PYCARD PROTEIN, MOUSE; RNA 16S;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMMENSAL; CONTROLLED STUDY; DISEASE PREDISPOSITION; DYSBIOSIS; FECES; FEMALE; INTESTINE FLORA; MALE; MATERNAL INHERITANCE; MICROBIAL COMMUNITY; MOUSE; NONHUMAN; PHYLOGENY; PRIORITY JOURNAL; PROTEIN FUNCTION; SPECIES DIVERSITY; ANIMAL; BACTERIUM; C57BL MOUSE; CELL CULTURE; CHEMICALLY INDUCED; COLITIS; GENETIC BACKGROUND; GENETICS; IMMUNOLOGY; INNATE IMMUNITY; KNOCKOUT MOUSE; METABOLISM; MICROBIOLOGY; MICROFLORA;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; BACTERIA; CELLS, CULTURED; COLITIS; DYSBIOSIS; FEMALE; GASTROINTESTINAL MICROBIOME; GENETIC BACKGROUND; IMMUNITY, INNATE; INFLAMMASOMES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROBIOTA; RECEPTORS, CELL SURFACE; RNA, RIBOSOMAL, 16S; SODIUM DODECYL SULFATE;

EID: 85027096132     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2017.07.011     Document Type: Article

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