메뉴 건너뛰기




Volumn 48, Issue 11, 2016, Pages 1407-1412

The effect of host genetics on the gut microbiome

(30)  Bonder, Marc Jan a   Kurilshikov, Alexander a,b,c   Tigchelaar, Ettje F a,d   Mujagic, Zlatan d,e   Imhann, Floris a   Vila, Arnau Vich a   Deelen, Patrick a   Vatanen, Tommi f,g   Schirmer, Melanie f,h   Smeekens, Sanne P i   Zhernakova, Daria V a   Jankipersadsing, Soesma A a   Jaeger, Martin i   Oosting, Marije i   Cenit, Maria Carmen a,k   Masclee, Ad A M e   Swertz, Morris A a   Li, Yang a   Kumar, Vinod a   Joosten, Leo i   more..


Author keywords

[No Author keywords available]

Indexed keywords

LECTIN;

EID: 84989832355     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.3663     Document Type: Article
Times cited : (615)

References (88)
  • 1
    • 84960417975 scopus 로고    scopus 로고
    • Gut microbiota composition associated with stool consistency
    • Tigchelaar, E.F. et al. Gut microbiota composition associated with stool consistency. Gut 65, 540-542 (2015).
    • (2015) Gut , vol.65 , pp. 540-542
    • Tigchelaar, E.F.1
  • 2
    • 84954286591 scopus 로고    scopus 로고
    • Proton pump inhibitors affect the gut microbiome
    • Imhann, F. et al. Proton pump inhibitors affect the gut microbiome. Gut 65, 740-748 (2015).
    • (2015) Gut , vol.65 , pp. 740-748
    • Imhann, F.1
  • 3
    • 84968901892 scopus 로고    scopus 로고
    • Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity
    • Zhernakova, A. et al. Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity. Science 352, 565-569 (2016).
    • (2016) Science , vol.352 , pp. 565-569
    • Zhernakova, A.1
  • 4
    • 84892828465 scopus 로고    scopus 로고
    • Diet rapidly and reproducibly alters the human gut microbiome
    • David, L.A. et al. Diet rapidly and reproducibly alters the human gut microbiome. Nature 505, 559-563 (2014).
    • (2014) Nature , vol.505 , pp. 559-563
    • David, L.A.1
  • 6
    • 84910096224 scopus 로고    scopus 로고
    • Human genetics shape the gut microbiome
    • Goodrich, J.K. et al. Human genetics shape the gut microbiome. Cell 159, 789-799 (2014).
    • (2014) Cell , vol.159 , pp. 789-799
    • Goodrich, J.K.1
  • 7
    • 84942846589 scopus 로고    scopus 로고
    • Genetic and environmental control of host-gut microbiota interactions
    • Org, E. et al. Genetic and environmental control of host-gut microbiota interactions. Genome Res. 25, 1558-1569 (2015).
    • (2015) Genome Res. , vol.25 , pp. 1558-1569
    • Org, E.1
  • 8
    • 84996479950 scopus 로고    scopus 로고
    • Host genetics and diet, but not immunoglobulin A expression, converge to shape compositional features of the gut microbiome in an advanced intercross population of mice
    • Leamy, L.J. et al. Host genetics and diet, but not immunoglobulin A expression, converge to shape compositional features of the gut microbiome in an advanced intercross population of mice. Genome Biol. 15, 552 (2014).
    • (2014) Genome Biol. , vol.15 , pp. 552
    • Leamy, L.J.1
  • 9
    • 84969492201 scopus 로고    scopus 로고
    • Genetic determinants of the gut microbiome in UK Twins
    • Goodrich, J.K. et al. Genetic determinants of the gut microbiome in UK Twins. Cell Host Microbe 19, 731-743 (2016).
    • (2016) Cell Host Microbe , vol.19 , pp. 731-743
    • Goodrich, J.K.1
  • 10
    • 84941647822 scopus 로고    scopus 로고
    • Host genetic variation impacts microbiome composition across human body sites
    • Blekhman, R. et al. Host genetic variation impacts microbiome composition across human body sites. Genome Biol. 16, 191 (2015).
    • (2015) Genome Biol. , vol.16 , pp. 191
    • Blekhman, R.1
  • 11
    • 84950978760 scopus 로고    scopus 로고
    • Genome-wide association studies of the human gut microbiota
    • Davenport, E.R. et al. Genome-wide association studies of the human gut microbiota. PLoS One 10, e0140301 (2015).
    • (2015) PLoS One , vol.10 , pp. e0140301
    • Davenport, E.R.1
  • 12
    • 84888869315 scopus 로고    scopus 로고
    • Genome-wide mapping of gene-microbiota interactions in susceptibility to autoimmune skin blistering
    • Srinivas, G. et al. Genome-wide mapping of gene-microbiota interactions in susceptibility to autoimmune skin blistering. Nat. Commun. 4, 2462 (2013).
    • (2013) Nat. Commun. , vol.4 , pp. 2462
    • Srinivas, G.1
  • 13
    • 84872156123 scopus 로고    scopus 로고
    • Genetic control of obesity and gut microbiota composition in response to high-fat, high-sucrose diet in mice
    • Parks, B.W. et al. Genetic control of obesity and gut microbiota composition in response to high-fat, high-sucrose diet in mice. Cell Metab. 17, 141-152 (2013).
    • (2013) Cell Metab. , vol.17 , pp. 141-152
    • Parks, B.W.1
  • 14
    • 84862491799 scopus 로고    scopus 로고
    • Murine gut microbiota is defned by host genetics and modulates variation of metabolic traits
    • McKnite, A.M. et al. Murine gut microbiota is defned by host genetics and modulates variation of metabolic traits. PLoS One 7, e39191 (2012).
    • (2012) PLoS One , vol.7 , pp. e39191
    • McKnite, A.M.1
  • 15
    • 84868336049 scopus 로고    scopus 로고
    • Host-microbe interactions have shaped the genetic architecture of infammatory bowel disease
    • Jostins, L. et al. Host-microbe interactions have shaped the genetic architecture of infammatory bowel disease. Nature 491, 119-124 (2012).
    • (2012) Nature , vol.491 , pp. 119-124
    • Jostins, L.1
  • 16
    • 84925541323 scopus 로고    scopus 로고
    • Complex host genetics infuence the microbiome in infammatory bowel disease
    • Knights, D. et al. Complex host genetics infuence the microbiome in infammatory bowel disease. Genome Med. 6, 107 (2014).
    • (2014) Genome Med. , vol.6 , pp. 107
    • Knights, D.1
  • 17
    • 84966526506 scopus 로고    scopus 로고
    • CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands
    • Lamas, B. et al. CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands. Nat. Med. 22, 598-605 (2016).
    • (2016) Nat. Med. , vol.22 , pp. 598-605
    • Lamas, B.1
  • 18
    • 84941588145 scopus 로고    scopus 로고
    • Cohort profle: LifeLines DEEP, a prospective, general population cohort study in the northern Netherlands: Study design and baseline characteristics
    • Tigchelaar, E.F. et al. Cohort profle: LifeLines DEEP, a prospective, general population cohort study in the northern Netherlands: study design and baseline characteristics. BMJ Open 5, e006772 (2015).
    • (2015) BMJ Open , vol.5 , pp. e006772
    • Tigchelaar, E.F.1
  • 19
    • 84982801611 scopus 로고    scopus 로고
    • Understanding human immune function using the resources from the Human Functional Genomics Project
    • Netea, M.G. et al. Understanding human immune function using the resources from the Human Functional Genomics Project. Nat. Med. 22, 831-833 (2016).
    • (2016) Nat. Med. , vol.22 , pp. 831-833
    • Netea, M.G.1
  • 20
    • 84904066325 scopus 로고    scopus 로고
    • Small intestinal permeability is increased in diarrhoea predominant IBS, while alterations in gastroduodenal permeability in all IBS subtypes are largely attributable to confounders
    • Mujagic, Z. et al. Small intestinal permeability is increased in diarrhoea predominant IBS, while alterations in gastroduodenal permeability in all IBS subtypes are largely attributable to confounders. Aliment. Pharmacol. Ther. 40, 288-297 (2014).
    • (2014) Aliment. Pharmacol. Ther. , vol.40 , pp. 288-297
    • Mujagic, Z.1
  • 21
    • 84908554334 scopus 로고    scopus 로고
    • Bacterial protein signals are associated with Crohn's disease
    • Juste, C. et al. Bacterial protein signals are associated with Crohn's disease. Gut 63, 1566-1577 (2014).
    • (2014) Gut , vol.63 , pp. 1566-1577
    • Juste, C.1
  • 22
    • 84994551051 scopus 로고    scopus 로고
    • O-011 Paneth cell phenotypes defne a subtype of pediatric Crohn's disease through alterations in host-microbial interactions
    • Liu, T.-C. et al. O-011 Paneth cell phenotypes defne a subtype of pediatric Crohn's disease through alterations in host-microbial interactions. Infamm. Bowel Dis. 22 (Suppl. 1), S4 (2016).
    • (2016) Infamm. Bowel Dis. , vol.22 , pp. S4
    • Liu, T.-C.1
  • 23
    • 84959450854 scopus 로고    scopus 로고
    • The features of mucosa-associated microbiota in primary sclerosing cholangitis
    • Torres, J. et al. The features of mucosa-associated microbiota in primary sclerosing cholangitis. Aliment. Pharmacol. Ther. 43, 790-801 (2016).
    • (2016) Aliment. Pharmacol. Ther. , vol.43 , pp. 790-801
    • Torres, J.1
  • 24
    • 84941979085 scopus 로고    scopus 로고
    • Genetic variants associated with motion sickness point to roles for inner ear development, neurological processes and glucose homeostasis
    • Hromatka, B.S. et al. Genetic variants associated with motion sickness point to roles for inner ear development, neurological processes and glucose homeostasis. Hum. Mol. Genet. 24, 2700-2708 (2015).
    • (2015) Hum. Mol. Genet. , vol.24 , pp. 2700-2708
    • Hromatka, B.S.1
  • 25
    • 84923171580 scopus 로고    scopus 로고
    • Genetic studies of body mass index yield new insights for obesity biology
    • Locke, A.E. et al. Genetic studies of body mass index yield new insights for obesity biology. Nature 518, 197-206 (2015).
    • (2015) Nature , vol.518 , pp. 197-206
    • Locke, A.E.1
  • 26
    • 84893716900 scopus 로고    scopus 로고
    • Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico
    • Williams, A.L. et al. Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico. Nature 506, 97-101 (2014).
    • (2014) Nature , vol.506 , pp. 97-101
    • Williams, A.L.1
  • 27
    • 84942870086 scopus 로고    scopus 로고
    • The gut microbiome contributes to a substantial proportion of the variation in blood lipids
    • Fu, J. et al. The gut microbiome contributes to a substantial proportion of the variation in blood lipids. Circ. Res. 117, 817-824 (2015).
    • (2015) Circ. Res. , vol.117 , pp. 817-824
    • Fu, J.1
  • 28
    • 84872969494 scopus 로고    scopus 로고
    • Gut microbiome composition is linked to whole grain-induced immunological improvements
    • Martínez, I. et al. Gut microbiome composition is linked to whole grain-induced immunological improvements. ISME J. 7, 269-280 (2013).
    • (2013) ISME J. , vol.7 , pp. 269-280
    • Martínez, I.1
  • 29
    • 84884543925 scopus 로고    scopus 로고
    • Characterization of the gut-associated microbiome in infammatory pouch complications following ileal pouch-anal anastomosis
    • Tyler, A.D. et al. Characterization of the gut-associated microbiome in infammatory pouch complications following ileal pouch-anal anastomosis. PLoS One 8, e66934 (2013).
    • (2013) PLoS One , vol.8 , pp. e66934
    • Tyler, A.D.1
  • 30
    • 84939203705 scopus 로고    scopus 로고
    • Variable alterations of the microbiota, without metabolic or immunological change, following faecal microbiota transplantation in patients with chronic pouchitis
    • Landy, J. et al. Variable alterations of the microbiota, without metabolic or immunological change, following faecal microbiota transplantation in patients with chronic pouchitis. Sci. Rep. 5, 12955 (2015).
    • (2015) Sci. Rep. , vol.5 , pp. 12955
    • Landy, J.1
  • 31
    • 33646589718 scopus 로고    scopus 로고
    • Vangl1 protein acts as a downstream effector of intestinal trefoil factor (ITF)/TFF3 signaling and regulates wound healing of intestinal epithelium
    • Kalabis, J., Rosenberg, I. & Podolsky, D.K. Vangl1 protein acts as a downstream effector of intestinal trefoil factor (ITF)/TFF3 signaling and regulates wound healing of intestinal epithelium. J. Biol. Chem. 281, 6434-6441 (2006).
    • (2006) J. Biol. Chem. , vol.281 , pp. 6434-6441
    • Kalabis, J.1    Rosenberg, I.2    Podolsky, D.K.3
  • 32
    • 84905495771 scopus 로고    scopus 로고
    • An unconventional KITENIN/ErbB4-mediated downstream signal of EGF upregulates c-Jun and the invasiveness of colorectal cancer cells
    • Bae, J.A. et al. An unconventional KITENIN/ErbB4-mediated downstream signal of EGF upregulates c-Jun and the invasiveness of colorectal cancer cells. Clin. Cancer Res. 20, 4115-4128 (2014).
    • (2014) Clin. Cancer Res. , vol.20 , pp. 4115-4128
    • Bae, J.A.1
  • 33
    • 79952811920 scopus 로고    scopus 로고
    • Expression of KITENIN in human colorectal cancer and its relation to tumor behavior and progression
    • Lee, S. et al. Expression of KITENIN in human colorectal cancer and its relation to tumor behavior and progression. Pathol. Int. 61, 210-220 (2011).
    • (2011) Pathol. Int. , vol.61 , pp. 210-220
    • Lee, S.1
  • 34
    • 42249097927 scopus 로고    scopus 로고
    • Inverse relation between dietary intake of naturally occurring plant sterols and serum cholesterol in northern Sweden
    • Klingberg, S. et al. Inverse relation between dietary intake of naturally occurring plant sterols and serum cholesterol in northern Sweden. Am. J. Clin. Nutr. 87, 993-1001 (2008).
    • (2008) Am. J. Clin. Nutr. , vol.87 , pp. 993-1001
    • Klingberg, S.1
  • 35
    • 79952015071 scopus 로고    scopus 로고
    • A genome-wide association study identifes novel loci associated with circulating IGF-I and IGFBP-3
    • Kaplan, R.C. et al. A genome-wide association study identifes novel loci associated with circulating IGF-I and IGFBP-3. Hum. Mol. Genet. 20, 1241-1251 (2011).
    • (2011) Hum. Mol. Genet. , vol.20 , pp. 1241-1251
    • Kaplan, R.C.1
  • 36
    • 44849086097 scopus 로고    scopus 로고
    • Genome-wide association scans identifed CTNNBL1 as a novel gene for obesity
    • Liu, Y.J. et al. Genome-wide association scans identifed CTNNBL1 as a novel gene for obesity. Hum. Mol. Genet. 17, 1803-1813 (2008).
    • (2008) Hum. Mol. Genet. , vol.17 , pp. 1803-1813
    • Liu, Y.J.1
  • 37
    • 80053405321 scopus 로고    scopus 로고
    • Genome-wide association identifes nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes
    • Strawbridge, R.J. et al. Genome-wide association identifes nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes. Diabetes 60, 2624-2634 (2011).
    • (2011) Diabetes , vol.60 , pp. 2624-2634
    • Strawbridge, R.J.1
  • 38
    • 84866283114 scopus 로고    scopus 로고
    • How can Faecalibacterium prausnitzii employ ribofavin for extracellular electron transfer? Antioxid
    • Khan, M.T., Browne, W.R., van Dijl, J.M. & Harmsen, H.J.M. How can Faecalibacterium prausnitzii employ ribofavin for extracellular electron transfer? Antioxid. Redox Signal. 17, 1433-1440 (2012).
    • (2012) Redox Signal. , vol.17 , pp. 1433-1440
    • Khan, M.T.1    Browne, W.R.2    Van Dijl, J.M.3    Harmsen, H.J.M.4
  • 39
    • 84866549438 scopus 로고    scopus 로고
    • Dysfunction of the intestinal microbiome in infammatory bowel disease and treatment
    • Morgan, X.C. et al. Dysfunction of the intestinal microbiome in infammatory bowel disease and treatment. Genome Biol. 13, R79 (2012).
    • (2012) Genome Biol. , vol.13 , pp. R79
    • Morgan, X.C.1
  • 40
  • 41
    • 84881030765 scopus 로고    scopus 로고
    • Meta-analysis of genome-wide association studies identifes ten loci infuencing allergic sensitization
    • Bønnelykke, K. et al. Meta-analysis of genome-wide association studies identifes ten loci infuencing allergic sensitization. Nat. Genet. 45, 902-906 (2013).
    • (2013) Nat. Genet. , vol.45 , pp. 902-906
    • Bønnelykke, K.1
  • 42
    • 84896092821 scopus 로고    scopus 로고
    • The treatment-naive microbiome in new-onset Crohn's disease
    • Gevers, D. et al. The treatment-naive microbiome in new-onset Crohn's disease. Cell Host Microbe 15, 382-392 (2014).
    • (2014) Cell Host Microbe , vol.15 , pp. 382-392
    • Gevers, D.1
  • 43
    • 84943454450 scopus 로고    scopus 로고
    • Crosstalk between gut microbiota and dietary lipids aggravates WAT infammation through TLR signaling
    • Caesar, R., Tremaroli, V., Kovatcheva-Datchary, P., Cani, P.D. & Bäckhed, F. Crosstalk between gut microbiota and dietary lipids aggravates WAT infammation through TLR signaling. Cell Metab. 22, 658-668 (2015).
    • (2015) Cell Metab. , vol.22 , pp. 658-668
    • Caesar, R.1    Tremaroli, V.2    Kovatcheva-Datchary, P.3    Cani, P.D.4    Bäckhed, F.5
  • 44
    • 84907960438 scopus 로고    scopus 로고
    • DAP1, a negative regulator of autophagy, controls SubAB-mediated apoptosis and autophagy
    • Yahiro, K. et al. DAP1, a negative regulator of autophagy, controls SubAB-mediated apoptosis and autophagy. Infect. Immun. 82, 4899-4908 (2014).
    • (2014) Infect. Immun. , vol.82 , pp. 4899-4908
    • Yahiro, K.1
  • 45
    • 77955716131 scopus 로고    scopus 로고
    • DAP1, a novel substrate of mTOR, negatively regulates autophagy
    • Koren, I., Reem, E. & Kimchi, A. DAP1, a novel substrate of mTOR, negatively regulates autophagy. Curr. Biol. 20, 1093-1098 (2010).
    • (2010) Curr. Biol. , vol.20 , pp. 1093-1098
    • Koren, I.1    Reem, E.2    Kimchi, A.3
  • 46
    • 70949087383 scopus 로고    scopus 로고
    • Infammatory bowel disease and mutations affecting the interleukin-10 receptor
    • Glocker, E.O. et al. Infammatory bowel disease and mutations affecting the interleukin-10 receptor. N. Engl. J. Med. 361, 2033-2045 (2009).
    • (2009) N. Engl. J. Med. , vol.361 , pp. 2033-2045
    • Glocker, E.O.1
  • 48
    • 0035089679 scopus 로고    scopus 로고
    • The impact of phospholipid transfer protein (PLTP) on HDL metabolism
    • Huuskonen, J., Olkkonen, V.M., Jauhiainen, M. & Ehnholm, C. The impact of phospholipid transfer protein (PLTP) on HDL metabolism. Atherosclerosis 155, 269-281 (2001).
    • (2001) Atherosclerosis , vol.155 , pp. 269-281
    • Huuskonen, J.1    Olkkonen, V.M.2    Jauhiainen, M.3    Ehnholm, C.4
  • 49
    • 66349101348 scopus 로고    scopus 로고
    • Apoprotein e as a lipid transport and signaling protein in the blood, liver, and artery wall
    • Getz, G.S. & Reardon, C.A. Apoprotein E as a lipid transport and signaling protein in the blood, liver, and artery wall. J. Lipid Res. 50 (Suppl.), S156-S161 (2009).
    • (2009) J. Lipid Res. , vol.50 , pp. S156-S161
    • Getz, G.S.1    Reardon, C.A.2
  • 50
    • 0346027235 scopus 로고    scopus 로고
    • Muscle-specifc Pparg deletion causes insulin resistance
    • Hevener, A.L. et al. Muscle-specifc Pparg deletion causes insulin resistance. Nat. Med. 9, 1491-1497 (2003).
    • (2003) Nat. Med. , vol.9 , pp. 1491-1497
    • Hevener, A.L.1
  • 51
    • 0036894397 scopus 로고    scopus 로고
    • PPARG F388L, a transactivation-defcient mutant, in familial partial lipodystrophy
    • Hegele, R.A., Cao, H., Frankowski, C., Mathews, S.T. & Leff, T. PPARG F388L, a transactivation-defcient mutant, in familial partial lipodystrophy. Diabetes 51, 3586-3590 (2002).
    • (2002) Diabetes , vol.51 , pp. 3586-3590
    • Hegele, R.A.1    Cao, H.2    Frankowski, C.3    Mathews, S.T.4    Leff, T.5
  • 52
    • 1842866370 scopus 로고    scopus 로고
    • Association of the Pro12Ala and C1431T variants of PPARG and their haplotypes with susceptibility to type 2 diabetes
    • Doney, A.S.F. et al. Association of the Pro12Ala and C1431T variants of PPARG and their haplotypes with susceptibility to type 2 diabetes. Diabetologia 47, 555-558 (2004).
    • (2004) Diabetologia , vol.47 , pp. 555-558
    • Doney, A.S.F.1
  • 53
    • 84860765166 scopus 로고    scopus 로고
    • ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner
    • Hao, H.-X. et al. ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner. Nature 485, 195-200 (2012).
    • (2012) Nature , vol.485 , pp. 195-200
    • Hao, H.-X.1
  • 54
    • 84959017482 scopus 로고    scopus 로고
    • Visualization of a short-range Wnt gradient in the intestinal stem-cell niche
    • Farin, H.F. et al. Visualization of a short-range Wnt gradient in the intestinal stem-cell niche. Nature 530, 340-343 (2016).
    • (2016) Nature , vol.530 , pp. 340-343
    • Farin, H.F.1
  • 55
    • 84899044321 scopus 로고    scopus 로고
    • ZNRF3 acts as a tumour suppressor by the Wnt signalling pathway in human gastric adenocarcinoma
    • Zhou, Y. et al. ZNRF3 acts as a tumour suppressor by the Wnt signalling pathway in human gastric adenocarcinoma. J. Mol. Histol. 44, 555-563 (2013).
    • (2013) J. Mol. Histol. , vol.44 , pp. 555-563
    • Zhou, Y.1
  • 56
    • 79960039016 scopus 로고    scopus 로고
    • Genetic adaptation of the antibacterial human innate immunity network
    • Casals, F. et al. Genetic adaptation of the antibacterial human innate immunity network. BMC Evol. Biol. 11, 202 (2011).
    • (2011) BMC Evol. Biol. , vol.11 , pp. 202
    • Casals, F.1
  • 57
    • 84893668843 scopus 로고    scopus 로고
    • Estimating the number of species in microbial diversity studies
    • Bunge, J., Willis, A. & Walsh, F. Estimating the number of species in microbial diversity studies. Annu. Rev. Stat. Appl. 1, 427-445 (2014).
    • (2014) Annu. Rev. Stat. Appl. , vol.1 , pp. 427-445
    • Bunge, J.1    Willis, A.2    Walsh, F.3
  • 58
    • 84927662069 scopus 로고    scopus 로고
    • Microbiota-mediated infammation and antimicrobial defense in the intestine
    • Caballero, S. & Pamer, E.G. Microbiota-mediated infammation and antimicrobial defense in the intestine. Annu. Rev. Immunol. 33, 227-256 (2015).
    • (2015) Annu. Rev. Immunol. , vol.33 , pp. 227-256
    • Caballero, S.1    Pamer, E.G.2
  • 59
    • 84929223565 scopus 로고    scopus 로고
    • Interplay between enterobactin, myeloperoxidase and lipocalin 2 regulates E. coli survival in the infamed gut
    • Singh, V. et al. Interplay between enterobactin, myeloperoxidase and lipocalin 2 regulates E. coli survival in the infamed gut. Nat. Commun. 6, 7113 (2015).
    • (2015) Nat. Commun. , vol.6 , pp. 7113
    • Singh, V.1
  • 60
    • 84892786901 scopus 로고    scopus 로고
    • Crohn's disease-associated adherent invasive Escherichia coli modulate levels of microRNAs in intestinal epithelial cells to reduce autophagy
    • Nguyen, H.T.T. et al. Crohn's disease-associated adherent invasive Escherichia coli modulate levels of microRNAs in intestinal epithelial cells to reduce autophagy. Gastroenterology 146, 508-519 (2014).
    • (2014) Gastroenterology , vol.146 , pp. 508-519
    • Nguyen, H.T.T.1
  • 61
    • 84941344904 scopus 로고    scopus 로고
    • The ATG16L1-T300A allele impairs clearance of pathosymbionts in the infamed ileal mucosa of Crohn's disease patients
    • Sadaghian Sadabad, M. et al. The ATG16L1-T300A allele impairs clearance of pathosymbionts in the infamed ileal mucosa of Crohn's disease patients. Gut 64, 1546-1552 (2014).
    • (2014) Gut , vol.64 , pp. 1546-1552
    • Sadaghian Sadabad, M.1
  • 62
    • 84920896754 scopus 로고    scopus 로고
    • C-type lectins in immunity: Recent developments
    • Dambuza, I.M. & Brown, G.D. C-type lectins in immunity: recent developments. Curr. Opin. Immunol. 32, 21-27 (2015).
    • (2015) Curr. Opin. Immunol. , vol.32 , pp. 21-27
    • Dambuza, I.M.1    Brown, G.D.2
  • 63
    • 84861964286 scopus 로고    scopus 로고
    • Interactions between commensal fungi and the C-type lectin receptor Dectin-1 infuence colitis
    • Iliev, I. D. et al. Interactions between commensal fungi and the C-type lectin receptor Dectin-1 infuence colitis. Science 336, 1314-1317 (2012).
    • (2012) Science , vol.336 , pp. 1314-1317
    • Iliev, I.D.1
  • 64
    • 34548287518 scopus 로고    scopus 로고
    • Evidence of still-ongoing convergence evolution of the lactase persistence T-13910 alleles in humans
    • Enattah, N.S. et al. Evidence of still-ongoing convergence evolution of the lactase persistence T-13910 alleles in humans. Am. J. Hum. Genet. 81, 615-625 (2007).
    • (2007) Am. J. Hum. Genet. , vol.81 , pp. 615-625
    • Enattah, N.S.1
  • 65
    • 33845900450 scopus 로고    scopus 로고
    • Convergent adaptation of human lactase persistence in Africa and Europe
    • Tishkoff, S.A. et al. Convergent adaptation of human lactase persistence in Africa and Europe. Nat. Genet. 39, 31-40 (2007).
    • (2007) Nat. Genet. , vol.39 , pp. 31-40
    • Tishkoff, S.A.1
  • 66
    • 19744379159 scopus 로고    scopus 로고
    • Adult-type hypolactasia and regulation of lactase expression
    • Troelsen, J.T. Adult-type hypolactasia and regulation of lactase expression. Biochim. Biophys. Acta 1723, 19-32 (2005).
    • (2005) Biochim. Biophys. Acta , vol.1723 , pp. 19-32
    • Troelsen, J.T.1
  • 67
    • 84878651372 scopus 로고    scopus 로고
    • Relative validity of the food frequency questionnaire used to assess dietary intake in the Leiden Longevity Study
    • Streppel, M.T. et al. Relative validity of the food frequency questionnaire used to assess dietary intake in the Leiden Longevity Study. Nutr. J. 12, 75 (2013).
    • (2013) Nutr. J. , vol.12 , pp. 75
    • Streppel, M.T.1
  • 68
    • 79960111873 scopus 로고    scopus 로고
    • Self-reported energy intake by FFQ compared with actual energy intake to maintain body weight in 516 adults
    • Siebelink, E., Geelen, A. & de Vries, J.H.M. Self-reported energy intake by FFQ compared with actual energy intake to maintain body weight in 516 adults. Br. J. Nutr. 106, 274-281 (2011).
    • (2011) Br. J. Nutr. , vol.106 , pp. 274-281
    • Siebelink, E.1    Geelen, A.2    De Vries, J.H.M.3
  • 69
    • 84905579746 scopus 로고    scopus 로고
    • Whole-genome sequence variation, population structure and demographic history of the Dutch population
    • Genome of the Netherlands Consortium. Whole-genome sequence variation, population structure and demographic history of the Dutch population. Nat. Genet. 46, 818-825 (2014).
    • (2014) Nat. Genet. , vol.46 , pp. 818-825
  • 70
    • 84863505871 scopus 로고    scopus 로고
    • OptiCall: A robust genotype-calling algorithm for rare, low-frequency and common variants
    • Shah, T.S. et al. optiCall: a robust genotype-calling algorithm for rare, low-frequency and common variants. Bioinformatics 28, 1598-1603 (2012).
    • (2012) Bioinformatics , vol.28 , pp. 1598-1603
    • Shah, T.S.1
  • 71
    • 84943171338 scopus 로고    scopus 로고
    • A global reference for human genetic variation
    • Auton, A. et al. A global reference for human genetic variation. Nature 526, 68-74 (2015).
    • (2015) Nature , vol.526 , pp. 68-74
    • Auton, A.1
  • 72
    • 84928813777 scopus 로고    scopus 로고
    • Genotype harmonizer: Automatic strand alignment and format conversion for genotype data integration
    • Deelen, P. et al. Genotype harmonizer: automatic strand alignment and format conversion for genotype data integration. BMC Res. Notes 7, 901 (2014).
    • (2014) BMC Res. Notes , vol.7 , pp. 901
    • Deelen, P.1
  • 73
    • 84871952176 scopus 로고    scopus 로고
    • Improved whole-chromosome phasing for disease and population genetic studies
    • Delaneau, O., Zagury, J.-F. & Marchini, J. Improved whole-chromosome phasing for disease and population genetic studies. Nat. Methods 10, 5-6 (2013).
    • (2013) Nat. Methods , vol.10 , pp. 5-6
    • Delaneau, O.1    Zagury, J.-F.2    Marchini, J.3
  • 74
    • 84863845193 scopus 로고    scopus 로고
    • Genotype imputation with thousands of genomes
    • Howie, B., Marchini, J. & Stephens, M. Genotype imputation with thousands of genomes. G3 (Bethesda) 1, 457-470 (2011).
    • (2011) G3 (Bethesda) , vol.1 , pp. 457-470
    • Howie, B.1    Marchini, J.2    Stephens, M.3
  • 75
    • 84908551473 scopus 로고    scopus 로고
    • Improved imputation quality of low-frequency and rare variants in European samples using the 'Genome of the Netherlands'
    • Deelen, P. et al. Improved imputation quality of low-frequency and rare variants in European samples using the 'Genome of The Netherlands'. Eur. J. Hum. Genet. 22, 1321-1326 (2014).
    • (2014) Eur. J. Hum. Genet. , vol.22 , pp. 1321-1326
    • Deelen, P.1
  • 76
    • 84878802935 scopus 로고    scopus 로고
    • Imputing amino acid polymorphisms in human leukocyte antigens
    • Jia, X. et al. Imputing amino acid polymorphisms in human leukocyte antigens. PLoS One 8, e64683 (2013).
    • (2013) PLoS One , vol.8 , pp. e64683
    • Jia, X.1
  • 77
    • 84905049901 scopus 로고    scopus 로고
    • Trimmomatic: A fexible trimmer for Illumina sequence data
    • Bolger, A.M., Lohse, M. & Usadel, B. Trimmomatic: a fexible trimmer for Illumina sequence data. Bioinformatics 30, 2114-2120 (2014).
    • (2014) Bioinformatics , vol.30 , pp. 2114-2120
    • Bolger, A.M.1    Lohse, M.2    Usadel, B.3
  • 78
    • 84964994621 scopus 로고    scopus 로고
    • MetaPhlAn2 for enhanced metagenomic taxonomic profling
    • Truong, D.T. et al. MetaPhlAn2 for enhanced metagenomic taxonomic profling. Nat. Methods 12, 902-903 (2015).
    • (2015) Nat. Methods , vol.12 , pp. 902-903
    • Truong, D.T.1
  • 79
    • 84862192725 scopus 로고    scopus 로고
    • The UniProt-GO Annotation database in 2011
    • Dimmer, E.C. et al. The UniProt-GO Annotation database in 2011. Nucleic Acids Res. 40, D565-D570 (2012).
    • (2012) Nucleic Acids Res. , vol.40 , pp. D565-D570
    • Dimmer, E.C.1
  • 80
    • 84946735654 scopus 로고    scopus 로고
    • Gene Ontology Consortium: Going forward
    • Gene Ontology Consortium. Gene Ontology Consortium: going forward. Nucleic Acids Res. 43, D1049-D1056 (2015).
    • (2015) Nucleic Acids Res. , vol.43 , pp. D1049-D1056
  • 81
    • 84964682615 scopus 로고    scopus 로고
    • Variation in microbiome LPS immunogenicity contributes to autoimmunity in humans
    • Vatanen, T. et al. Variation in microbiome LPS immunogenicity contributes to autoimmunity in humans. Cell 165, 842-853 (2016).
    • (2016) Cell , vol.165 , pp. 842-853
    • Vatanen, T.1
  • 82
    • 84885018609 scopus 로고    scopus 로고
    • Systematic identifcation of trans eQTLs as putative drivers of known disease associations
    • Westra, H.-J. et al. Systematic identifcation of trans eQTLs as putative drivers of known disease associations. Nat. Genet. 45, 1238-1243 (2013).
    • (2013) Nat. Genet. , vol.45 , pp. 1238-1243
    • Westra, H.-J.1
  • 85
    • 84905661532 scopus 로고    scopus 로고
    • Pattern recognition and signaling mechanisms of RIG-I and MDA5
    • Reikine, S., Nguyen, J.B. & Modis, Y. Pattern recognition and signaling mechanisms of RIG-I and MDA5. Front. Immunol. 5, 342 (2014).
    • (2014) Front. Immunol. , vol.5 , pp. 342
    • Reikine, S.1    Nguyen, J.B.2    Modis, Y.3
  • 86
    • 28444493739 scopus 로고    scopus 로고
    • Combining probability from independent tests: The weighted Z-method is superior to Fisher's approach
    • Whitlock, M.C. Combining probability from independent tests: the weighted Z-method is superior to Fisher's approach. J. Evol. Biol. 18, 1368-1373 (2005).
    • (2005) J. Evol. Biol. , vol.18 , pp. 1368-1373
    • Whitlock, M.C.1
  • 87
    • 84929001104 scopus 로고    scopus 로고
    • The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans
    • Ardlie, K.G. et al. The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans. Science 348, 648-660 (2015).
    • (2015) Science , vol.348 , pp. 648-660
    • Ardlie, K.G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.