Inflammatory Ly6Chi monocytes and their conversion to M2 macrophages drive atherosclerosis regression

Journal of Clinical Investigation

Volumn 127, Issue 8, 2017, Pages 2904-2915

  Rahman, Karishma ^a   Vengrenyuk, Yuliya ^b   Ramsey, Stephen A ^c   Vila, Noemi Rotllan ^d   Girgis, Natasha M ^e   Liu, Jianhua ^b   Gusarova, Viktoria ^f   Gromada, Jesper ^f   Weinstock, Ada ^a   Moore, Kathryn J ^a   Loke, P'ng ^a   Fisher, Edward A ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c 1148 Kelley Engineering Center Corvallis   (United States)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e Department of Lead Discovery   (United States)

^f REGENERON PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CX3CR1; CHLORDANE; INTERLEUKIN 13; INTERLEUKIN 4; MONOCYTE CHEMOTACTIC PROTEIN 1; RNA; STAT6 PROTEIN; CCR2 PROTEIN, MOUSE; CCR5 PROTEIN, MOUSE; CHEMOKINE RECEPTOR; CX3CR1 PROTEIN, MOUSE; STAT6 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATHEROSCLEROTIC PLAQUE; CELL COUNT; CELL FATE; CONTROLLED STUDY; INFLAMMATION; LY6C MONOCYTE; MACROPHAGE; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RNA SEQUENCE; SINGLE CELL ANALYSIS; ANIMAL; AORTA; ATHEROSCLEROSIS; BLOOD; C57BL MOUSE; CELL LINEAGE; CYTOLOGY; FEMALE; GENETICS; HYPERLIPIDEMIA; KNOCKOUT MOUSE; MALE; METABOLISM; PHENOTYPE; PHYSIOLOGY; SEQUENCE ANALYSIS; TREATMENT OUTCOME;

ANIMALS; AORTA; ATHEROSCLEROSIS; CELL LINEAGE; FEMALE; HYPERLIPIDEMIAS; INFLAMMATION; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MONOCYTES; PHENOTYPE; PLAQUE, ATHEROSCLEROTIC; RECEPTORS, CCR2; RECEPTORS, CCR5; RECEPTORS, CHEMOKINE; SEQUENCE ANALYSIS, RNA; STAT6 TRANSCRIPTION FACTOR; TREATMENT OUTCOME;

EID: 85026667743     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI75005     Document Type: Article

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