Hyperglycemia promotes myelopoiesis and impairs the resolution of atherosclerosis

Cell Metabolism

Volumn 17, Issue 5, 2013, Pages 695-708

  Nagareddy, Prabhakara R ^a   Murphy, Andrew J ^a   Stirzaker, Roslynn A ^a   Hu, Yunying ^a   Yu, Shiquing ^a   Miller, Rachel G ^b   Ramkhelawon, Bhama ^c   Distel, Emilie ^c   Westerterp, Marit ^a   Huang, Li Shin ^a   Schmidt, Ann Marie ^c   Orchard, Trevor J ^b   Fisher, Edward A ^c   Tall, Alan R ^a   Goldberg, Ira J ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^c NEW YORK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALGRANULIN A; CALGRANULIN B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; BONE MARROW; CELL PROLIFERATION; CONTROLLED STUDY; CORONARY ARTERY DISEASE; CYTOKINE PRODUCTION; GLYCATION; HYPERGLYCEMIA; INSULIN DEPENDENT DIABETES MELLITUS; LEUKOCYTE COUNT; LEUKOCYTOSIS; MALE; MONOCYTE; MONOCYTOSIS; MOUSE; MYELOID PROGENITOR CELL; MYELOPOIESIS; NEUTROPHIL; NEUTROPHILIA; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ATHEROSCLEROSIS; BONE MARROW; CORONARY DISEASE; CYTOKINES; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; GLUCOSE; GLYCOSYLATION END PRODUCTS, ADVANCED; HUMANS; HYPERGLYCEMIA; LEUKOCYTES; LEUKOCYTOSIS; MALE; MICE; MICE, INBRED C57BL; MONOCYTES; MYELOID PROGENITOR CELLS; MYELOPOIESIS; NEUTROPHILS; NF-KAPPA B; RECEPTORS, IMMUNOLOGIC;

EID: 84877270004     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2013.04.001     Document Type: Article

References (48)

1. M.M. Averill, S. Barnhart, L. Becker, X. Li, J.W. Heinecke, R.C. Leboeuf, J.A. Hamerman, C. Sorg, C. Kerkhoff, and K.E. Bornfeldt S100A9 differentially modifies phenotypic states of neutrophils, macrophages, and dendritic cells: implications for atherosclerosis and adipose tissue inflammation Circulation 123 2011 1216 1226
2. K.E. Bornfeldt, and I. Tabas Insulin resistance, hyperglycemia, and atherosclerosis Cell Metab. 14 2011 575 585
3. L.G. Bucciarelli, T. Wendt, W. Qu, Y. Lu, E. Lalla, L.L. Rong, M.T. Goova, B. Moser, T. Kislinger, and D.C. Lee RAGE blockade stabilizes established atherosclerosis in diabetic apolipoprotein E-null mice Circulation 106 2002 2827 2835
4. M.J. Christopher, M. Rao, F. Liu, J.R. Woloszynek, and D.C. Link Expression of the G-CSF receptor in monocytic cells is sufficient to mediate hematopoietic progenitor mobilization by G-CSF in mice J. Exp. Med. 208 2011 251 260
5. B.S. Coller Leukocytosis and ischemic vascular disease morbidity and mortality: is it time to intervene? Arterioscler. Thromb. Vasc. Biol. 25 2005 658 670
6. K. Croce, H. Gao, Y. Wang, T. Mooroka, M. Sakuma, C. Shi, G.K. Sukhova, R.R. Packard, N. Hogg, P. Libby, and D.I. Simon Myeloid-related protein-8/14 is critical for the biological response to vascular injury Circulation 120 2009 427 436
7. J.M. Daley, A.A. Thomay, M.D. Connolly, J.S. Reichner, and J.E. Albina Use of Ly6G-specific monoclonal antibody to deplete neutrophils in mice J. Leukoc. Biol. 83 2008 64 70
8. J. Danesh, R. Collins, P. Appleby, and R. Peto Association of fibrinogen, C-reactive protein, albumin, or leukocyte count with coronary heart disease: meta-analyses of prospective studies JAMA 279 1998 1477 1482
9. M. Drechsler, R.T. Megens, M. van Zandvoort, C. Weber, and O. Soehnlein Hyperlipidemia-triggered neutrophilia promotes early atherosclerosis Circulation 122 2010 1837 1845
10. G.L. Duff, and T.P. Payne The effect of alloxan diabetes on experimental cholesterol atherosclerosis in the rabbit. III. The mechanism of the inhibition of experimental cholesterol atherosclerosis in alloxan-diabetic rabbits J. Exp. Med. 92 1950 299 317
11. J.E. Feig, I. Pineda-Torra, M. Sanson, M.N. Bradley, Y. Vengrenyuk, D. Bogunovic, E.L. Gautier, D. Rubinstein, C. Hong, and J. Liu LXR promotes the maximal egress of monocyte-derived cells from mouse aortic plaques during atherosclerosis regression J. Clin. Invest. 120 2010 4415 4424
12. F. Ferraro, S. Lymperi, S. Méndez-Ferrer, B. Saez, J.A. Spencer, B.Y. Yeap, E. Masselli, G. Graiani, L. Prezioso, and E.L. Rizzini Diabetes impairs hematopoietic stem cell mobilization by altering niche function Sci. Transl. Med. 3 2011 ra101
13. E.S. Ford Leukocyte count, erythrocyte sedimentation rate, and diabetes incidence in a national sample of US adults Am. J. Epidemiol. 155 2002 57 64
14. R. Förster, A. Schubel, D. Breitfeld, E. Kremmer, I. Renner-Müller, E. Wolf, and M. Lipp CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs Cell 99 1999 23 33
15. K. Fujiu, I. Manabe, and R. Nagai Renal collecting duct epithelial cells regulate inflammation in tubulointerstitial damage in mice J. Clin. Invest. 121 2011 3425 3441
16. E. Harja, D.X. Bu, B.I. Hudson, J.S. Chang, X. Shen, K. Hallam, A.Z. Kalea, Y. Lu, R.H. Rosario, and S. Oruganti Vascular and inflammatory stresses mediate atherosclerosis via RAGE and its ligands in apoE-/- mice J. Clin. Invest. 118 2008 183 194
17. A.M. Healy, M.D. Pickard, A.D. Pradhan, Y. Wang, Z. Chen, K. Croce, M. Sakuma, C. Shi, A.C. Zago, and J. Garasic Platelet expression profiling and clinical validation of myeloid-related protein-14 as a novel determinant of cardiovascular events Circulation 113 2006 2278 2284
18. T. Hiro, T. Kimura, T. Morimoto, K. Miyauchi, Y. Nakagawa, M. Yamagishi, Y. Ozaki, K. Kimura, S. Saito, T. Yamaguchi JAPAN-ACS Investigators Diabetes mellitus is a major negative determinant of coronary plaque regression during statin therapy in patients with acute coronary syndrome - serial intravascular ultrasound observations from the Japan Assessment of Pitavastatin and Atorvastatin in Acute Coronary Syndrome Trial (the JAPAN-ACS Trial) Circ. J. 74 2010 1165 1174
19. M.A. Hofmann, S. Drury, C. Fu, W. Qu, A. Taguchi, Y. Lu, C. Avila, N. Kambham, A. Bierhaus, and P. Nawroth RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides Cell 97 1999 889 901
20. N. Leukert, T. Vogl, K. Strupat, R. Reichelt, C. Sorg, and J. Roth Calcium-dependent tetramer formation of S100A8 and S100A9 is essential for biological activity J. Mol. Biol. 359 2006 961 972
21. G.J. Lieschke, D. Grail, G. Hodgson, D. Metcalf, E. Stanley, C. Cheers, K.J. Fowler, S. Basu, Y.F. Zhan, and A.R. Dunn Mice lacking granulocyte colony-stimulating factor have chronic neutropenia, granulocyte and macrophage progenitor cell deficiency, and impaired neutrophil mobilization Blood 84 1994 1737 1746
22. W. Meng, B.A. Ellsworth, A.A. Nirschl, P.J. McCann, M. Patel, R.N. Girotra, G. Wu, P.M. Sher, E.P. Morrison, and S.A. Biller Discovery of dapagliflozin: a potent, selective renal sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor for the treatment of type 2 diabetes J. Med. Chem. 51 2008 1145 1149
23. S. Morris-Rosenfeld, E. Blessing, M.R. Preusch, C. Albrecht, A. Bierhaus, M. Andrassy, P.P. Nawroth, M.E. Rosenfeld, H.A. Katus, and F. Bea Deletion of bone marrow-derived receptor for advanced glycation end products inhibits atherosclerotic plaque progression Eur. J. Clin. Invest. 41 2011 1164 1171
24. A.J. Murphy, K.J. Woollard, A. Hoang, N. Mukhamedova, R.A. Stirzaker, S.P. McCormick, A.T. Remaley, D. Sviridov, and J. Chin-Dusting High-density lipoprotein reduces the human monocyte inflammatory response Arterioscler. Thromb. Vasc. Biol. 28 2008 2071 2077
25. A.J. Murphy, M. Akhtari, S. Tolani, T. Pagler, N. Bijl, C.L. Kuo, M. Wang, M. Sanson, S. Abramowicz, and C. Welch ApoE regulates hematopoietic stem cell proliferation, monocytosis, and monocyte accumulation in atherosclerotic lesions in mice J. Clin. Invest. 121 2011 4138 4149
26. S.J. Nicholls, C.M. Ballantyne, P.J. Barter, M.J. Chapman, R.M. Erbel, P. Libby, J.S. Raichlen, K. Uno, M. Borgman, K. Wolski, and S.E. Nissen Effect of two intensive statin regimens on progression of coronary disease N. Engl. J. Med. 365 2011 2078 2087
27. T.J. Orchard, J.C. Olson, J.R. Erbey, K. Williams, K.Y. Forrest, L. Smithline Kinder, D. Ellis, and D.J. Becker Insulin resistance-related factors, but not glycemia, predict coronary artery disease in type 1 diabetes: 10-year follow-up data from the Pittsburgh Epidemiology of Diabetes Complications Study Diabetes Care 26 2003 1374 1379
28. S. Parathath, L. Grauer, L.S. Huang, M. Sanson, E. Distel, I.J. Goldberg, and E.A. Fisher Diabetes adversely affects macrophages during atherosclerotic plaque regression in mice Diabetes 60 2011 1759 1769
29. L. Park, K.G. Raman, K.J. Lee, Y. Lu, L.J. Ferran Jr., W.S. Chow, D. Stern, and A.M. Schmidt Suppression of accelerated diabetic atherosclerosis by the soluble receptor for advanced glycation endproducts Nat. Med. 4 1998 1025 1031
30. S.U. Persson, H. Larsson, and H. Odeberg Reduced number of circulating monocytes after institution of insulin therapy - relevance for development of atherosclerosis in diabetics? Angiology 49 1998 423 433
31. S. Potteaux, E.L. Gautier, S.B. Hutchison, N. van Rooijen, D.J. Rader, M.J. Thomas, M.G. Sorci-Thomas, and G.J. Randolph Suppressed monocyte recruitment drives macrophage removal from atherosclerotic plaques of Apoe-/- mice during disease regression J. Clin. Invest. 121 2011 2025 2036
32. P. Reaven, S. Merat, F. Casanada, M. Sutphin, and W. Palinski Effect of streptozotocin-induced hyperglycemia on lipid profiles, formation of advanced glycation endproducts in lesions, and extent of atherosclerosis in LDL receptor-deficient mice Arterioscler. Thromb. Vasc. Biol. 17 1997 2250 2256
33. C.S. Robbins, A. Chudnovskiy, P.J. Rauch, J.L. Figueiredo, Y. Iwamoto, R. Gorbatov, M. Etzrodt, G.F. Weber, T. Ueno, and N. van Rooijen Extramedullary hematopoiesis generates Ly-6C(high) monocytes that infiltrate atherosclerotic lesions Circulation 125 2012 364 374 10.1161/CIRCULATIONAHA.111.061986 Published online December 5, 2011
34. A.W. Roberts G-CSF: a key regulator of neutrophil production, but that's not all! Growth Factors 23 2005 33 41
35. M.I. Schmidt, B.B. Duncan, A.R. Sharrett, G. Lindberg, P.J. Savage, S. Offenbacher, M.I. Azambuja, R.P. Tracy, and G. Heiss Markers of inflammation and prediction of diabetes mellitus in adults (Atherosclerosis Risk in Communities study): a cohort study Lancet 353 1999 1649 1652
36. C.L. Semerad, J. Poursine-Laurent, F. Liu, and D.C. Link A role for G-CSF receptor signaling in the regulation of hematopoietic cell function but not lineage commitment or differentiation Immunity 11 1999 153 161
37. A. Soro-Paavonen, A.M. Watson, J. Li, K. Paavonen, A. Koitka, A.C. Calkin, D. Barit, M.T. Coughlan, B.G. Drew, and G.I. Lancaster Receptor for advanced glycation end products (RAGE) deficiency attenuates the development of atherosclerosis in diabetes Diabetes 57 2008 2461 2469
38. F.K. Swirski, P. Libby, E. Aikawa, P. Alcaide, F.W. Luscinskas, R. Weissleder, and M.J. Pittet Ly-6Chi monocytes dominate hypercholesterolemia- associated monocytosis and give rise to macrophages in atheromata J. Clin. Invest. 117 2007 195 205
39. F. Tacke, D. Alvarez, T.J. Kaplan, C. Jakubzick, R. Spanbroek, J. Llodra, A. Garin, J. Liu, M. Mack, and N. van Rooijen Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques J. Clin. Invest. 117 2007 185 194
40. P.C. Tong, K.F. Lee, W.Y. So, M.H. Ng, W.B. Chan, M.K. Lo, N.N. Chan, and J.C. Chan White blood cell count is associated with macro- and microvascular complications in chinese patients with type 2 diabetes Diabetes Care 27 2004 216 222
41. E. Trogan, J.E. Feig, S. Dogan, G.H. Rothblat, V. Angeli, F. Tacke, G.J. Randolph, and E.A. Fisher Gene expression changes in foam cells and the role of chemokine receptor CCR7 during atherosclerosis regression in ApoE-deficient mice Proc. Natl. Acad. Sci. USA 103 2006 3781 3786
42. A.J. van Oostrom, J.P. van Wijk, T.P. Sijmonsma, T.J. Rabelink, and M. Castro Cabezas Increased expression of activation markers on monocytes and neutrophils in type 2 diabetes Neth. J. Med. 62 2004 320 325
43. T. Vogl, K. Tenbrock, S. Ludwig, N. Leukert, C. Ehrhardt, M.A. van Zoelen, W. Nacken, D. Foell, T. van der Poll, C. Sorg, and J. Roth Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock Nat. Med. 13 2007 1042 1049
44. S. Vuckovic, G. Withers, M. Harris, D. Khalil, D. Gardiner, I. Flesch, S. Tepes, R. Greer, D. Cowley, A. Cotterill, and D.N. Hart Decreased blood dendritic cell counts in type 1 diabetic children Clin. Immunol. 123 2007 281 288
45. K.E. Wellen, and G.S. Hotamisligil Inflammation, stress, and diabetes J. Clin. Invest. 115 2005 1111 1119
46. S.J. Woo, S.J. Ahn, J. Ahn, K.H. Park, and K. Lee Elevated systemic neutrophil count in diabetic retinopathy and diabetes: a hospital-based cross-sectional study of 30,793 Korean subjects Invest. Ophthalmol. Vis. Sci. 52 2011 7697 7703
47. D. Yao, and M. Brownlee Hyperglycemia-induced reactive oxygen species increase expression of the receptor for advanced glycation end products (RAGE) and RAGE ligands Diabetes 59 2010 249 255
48. L. Yvan-Charvet, T. Pagler, E.L. Gautier, S. Avagyan, R.L. Siry, S. Han, C.L. Welch, N. Wang, G.J. Randolph, H.W. Snoeck, and A.R. Tall ATP-binding cassette transporters and HDL suppress hematopoietic stem cell proliferation Science 328 2010 1689 1693