-
1
-
-
79956319051
-
Progress and challenges in translating the biology of atherosclerosis
-
P. Libby, P. M. Ridker, G. K. Hansson, Progress and challenges in translating the biology of atherosclerosis. Nature 473, 317-325 (2011).
-
(2011)
Nature
, vol.473
, pp. 317-325
-
-
Libby, P.1
Ridker, P.M.2
Hansson, G.K.3
-
2
-
-
84872166189
-
Leukocyte behavior in atherosclerosis, myocardial infarction, and heart failure
-
F. K. Swirski, M. Nahrendorf, Leukocyte behavior in atherosclerosis, myocardial infarction, and heart failure. Science 339, 161-166 (2013).
-
(2013)
Science
, vol.339
, pp. 161-166
-
-
Swirski, F.K.1
Nahrendorf, M.2
-
3
-
-
84872130535
-
Anti-inflammatory therapy in chronic disease: Challenges and opportunities
-
I. Tabas, C. K. Glass, Anti-inflammatory therapy in chronic disease: Challenges and opportunities. Science 339, 166-172 (2013).
-
(2013)
Science
, vol.339
, pp. 166-172
-
-
Tabas, I.1
Glass, C.K.2
-
4
-
-
84886797808
-
Macrophages in atherosclerosis: A dynamic balance
-
K. J. Moore, F. J. Sheedy, E. A. Fisher, Macrophages in atherosclerosis: A dynamic balance. Nat Rev. Immunol. 13, 709-721 (2013).
-
(2013)
Nat Rev. Immunol.
, vol.13
, pp. 709-721
-
-
Moore, K.J.1
Sheedy, F.J.2
Fisher, E.A.3
-
5
-
-
72949116358
-
Macrophage death and defective inflammation resolution in atherosclerosis
-
I. Tabas, Macrophage death and defective inflammation resolution in atherosclerosis. Nat. Rev. Immunol. 10, 36-46 (2010).
-
(2010)
Nat. Rev. Immunol.
, vol.10
, pp. 36-46
-
-
Tabas, I.1
-
6
-
-
79955503060
-
-/- mice during disease regression. J
-
S. Potteaux, E.L.Gautier,S. B.Hutchison, N.van Rooijen,D.J. Rader, M.J.Thomas,M.G.SorcThomas, G. J. Randolph, Suppressed monocyte recruitment drives macrophage removal from atherosclerotic plaques of Apoe-/- mice during disease regression. J. Clin. Invest. 121, 2025-2036 (2011).
-
(2011)
Clin. Invest.
, vol.121
, pp. 2025-2036
-
-
Potteaux, S.1
Gautier, E.L.2
Hutchison, S.B.3
Van Rooijen, N.4
Rader, D.J.5
Thomas, M.J.6
Sorc Thomas, M.G.7
Randolph, G.J.8
-
7
-
-
80155200721
-
Therapeutic siRNA silencing in inflammatory monocytes in mice
-
F. Leuschner, P. Dutta, R. Gorbatov, T. I. Novobrantseva, J. S. Donahoe, G. Courties, K. M. Lee, J. I. Kim, J. F. Markmann, B. Marinelli, P. Panizzi, W. W. Lee, Y. Iwamoto, S. Milstein, H. Epstein-Barash, W. Cantley, J. Wong, V. Cortez-Retamozo, A. Newton, K. Love, P. Libby, M. J. Pittet, F. K. Swirski, V. Koteliansky, R. Langer, R. Weissleder, D. G. Anderson, M. Nahrendorf, Therapeutic siRNA silencing in inflammatory monocytes in mice. Nat. Biotechnol. 29,1005-1010 (2011).
-
(2011)
Nat. Biotechnol.
, vol.29
, pp. 1005-1010
-
-
Leuschner, F.1
Dutta, P.2
Gorbatov, R.3
Novobrantseva, T.I.4
Donahoe, J.S.5
Courties, G.6
Lee, K.M.7
Kim, J.I.8
Markmann, J.F.9
Marinelli, B.10
Panizzi, P.11
Lee, W.W.12
Iwamoto, Y.13
Milstein, S.14
Epstein-Barash, H.15
Cantley, W.16
Wong, J.17
Cortez-Retamozo, V.18
Newton, A.19
Love, K.20
Libby, P.21
Pittet, M.J.22
Swirski, F.K.23
Koteliansky, V.24
Langer, R.25
Weissleder, R.26
Anderson, D.G.27
Nahrendorf, M.28
more..
-
8
-
-
65249123061
-
Macrophage deficiency of p38a MAPK promotes apoptosis and plaque necrosis in advanced atherosclerotic lesions in mice
-
T. A. Seimon, Y. Wang, S. Han, T. Senokuchi, D. M. Schrijvers, G. Kuriakose, A. R. Tall, I. A. Tabas, Macrophage deficiency of p38a MAPK promotes apoptosis and plaque necrosis in advanced atherosclerotic lesions in mice. J. Clin. Invest. 119, 886-898 (2009).
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 886-898
-
-
Seimon, T.A.1
Wang, Y.2
Han, S.3
Senokuchi, T.4
Schrijvers, D.M.5
Kuriakose, G.6
Tall, A.R.7
Tabas, I.A.8
-
9
-
-
77956943493
-
A light-activated theranostic nano-agent for targeted macrophage ablation in inflammatory atherosclerosis
-
J. R. McCarthy, E. Korngold, R. Weissleder, F. a Jaffer, A light-activated theranostic nano-agent for targeted macrophage ablation in inflammatory atherosclerosis. Small 6, 2041-2049 (2010).
-
(2010)
Small
, vol.6
, pp. 2041-2049
-
-
McCarthy, J.R.1
Korngold, E.2
Weissleder, R.3
Jaffer, F.A.4
-
10
-
-
82755192460
-
Statins promote the regression of atherosclerosis via activation of the CCR7-dependent emigration pathway in macrophages
-
J.E. Feig, Y. Shang, N. Rotllan, Y. Vengrenyuk, C. Wu, R. Shamir, LP. Torra, C. Fernandez-Hernando, E. A. Fisher, M.J. Garabedian, Statins promote the regression of atherosclerosis via activation of the CCR7-dependent emigration pathway in macrophages. PLOS One 6, e28534 (2011).
-
(2011)
PLOS One
, vol.6
, pp. e28534
-
-
Feig, J.E.1
Shang, Y.2
Rotllan, N.3
Vengrenyuk, Y.4
Wu, C.5
Shamir, R.6
Torra, L.P.7
Fernandez-Hernando, C.8
Fisher, E.A.9
Garabedian, M.J.10
-
11
-
-
79958715229
-
Local macrophage proliferation, rather than recruitment from the blood, is a signature of TH2 inflammation
-
S.J.Jenkins, D. Ruckerl, P. C. Cook, L. H.Jones, F. D. Finkelman, N.van Rooijen, A. S. MacDonald, J. E. Allen, Local macrophage proliferation, rather than recruitment from the blood, is a signature of TH2 inflammation. Science 332, 1284-1288 (2011).
-
(2011)
Science
, vol.332
, pp. 1284-1288
-
-
Jenkins, S.J.1
Ruckerl, D.2
Cook, P.C.3
Jones, L.H.4
Finkelman, F.D.5
Van Rooijen, N.6
MacDonald, A.S.7
Allen, J.E.8
-
12
-
-
84876775203
-
Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes
-
D. Hashimoto, A. Chow, C. Noizat, P. Teo, M. B. Beasley, M. Leboeuf, C D. Becker, P. See, J. Price, D. Lucas, M. Greter, A. Mortha, S. W. Boyer, E. C Forsberg, M.Tanaka, N. van Rooijen, A. Garcfa-Sastre, E. R. Stanley, F. Ginhoux, P. S. Frenette, M. Merad, Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes. Immunity 38, 792-804 (2013).
-
(2013)
Immunity
, vol.38
, pp. 792-804
-
-
Hashimoto, D.1
Chow, A.2
Noizat, C.3
Teo, P.4
Beasley, M.B.5
Leboeuf, M.6
Becker, C.D.7
See, P.8
Price, J.9
Lucas, D.10
Greter, M.11
Mortha, A.12
Boyer, S.W.13
Forsberg, E.C.14
Tanaka, M.15
Van Rooijen, N.16
Garcfa-Sastre, A.17
Stanley, E.R.18
Ginhoux, F.19
Frenette, P.S.20
Merad, M.21
more..
-
13
-
-
84872765982
-
Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis
-
S. Yona, K. W. Kim, Y. Wolf, A. Mildner, D. Varol, M. Breker, D. Strauss-Ayali, S. Viukov, M. Guilliams, A. Misharin, D. A. Hume, H. Perlman, B. Malissen, E. Zelzer, S. Jung, Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis. Immunity 38, 79-91 (2013).
-
(2013)
Immunity
, vol.38
, pp. 79-91
-
-
Yona, S.1
Kim, K.W.2
Wolf, Y.3
Mildner, A.4
Varol, D.5
Breker, M.6
Strauss-Ayali, D.7
Viukov, S.8
Guilliams, M.9
Misharin, A.10
Hume, D.A.11
Perlman, H.12
Malissen, B.13
Zelzer, E.14
Jung, S.15
-
14
-
-
84883800208
-
Local proliferation dominates lesional macrophage accumulation in atherosclerosis
-
C. S. Robbins, I. Hilgendorf, G. F. Weber, I. Theurl, Y. Iwamoto, J. L. Figueiredo, R. Gorbatov, G. KSukhova, L. M. Gerhardt, D. Smyth, C. C. Zavitz, E. A. Shikatani, M. Parsons, N. van Rooijen, H. Y. Lin, M. Husain, P. Libby, M. Nahrendorf, R. Weissleder, F. K. Swirski, Local proliferation dominates lesional macrophage accumulation in atherosclerosis. Nat. MedA 9,1166-1172 (2013).
-
(2013)
Nat. MedA
, vol.9
, pp. 1166-1172
-
-
Robbins, C.S.1
Hilgendorf, I.2
Weber, G.F.3
Theurl, I.4
Iwamoto, Y.5
Figueiredo, J.L.6
Gorbatov, R.7
Sukhova, G.K.8
Gerhardt, L.M.9
Smyth, D.10
Zavitz, C.C.11
Shikatani, E.A.12
Parsons, M.13
Van Rooijen, N.14
Lin, H.Y.15
Husain, M.16
Libby, P.17
Nahrendorf, M.18
Weissleder, R.19
Swirski, F.K.20
more..
-
15
-
-
0019135838
-
Multivalent feedback regulation of HMG CoA reductase, a control mechanism coordinating isoprenoid synthesis and cell growth
-
M. S. Brown, J. L. Goldstein, Multivalent feedback regulation of HMG CoA reductase, a control mechanism coordinating isoprenoid synthesis and cell growth. J. Lipid Res. 21,505-517 (1980).
-
(1980)
J. Lipid Res.
, vol.21
, pp. 505-517
-
-
Brown, M.S.1
Goldstein, J.L.2
-
16
-
-
31844451010
-
Anti-inflammatory effects of statins: Clinical evidence and basic mechanisms
-
M. K. Jain, P. M. Ridker, Anti-inflammatory effects of statins: Clinical evidence and basic mechanisms. Nat. Rev. Drug Discov. 4, 977-987 (2005).
-
(2005)
Nat. Rev. Drug Discov.
, vol.4
, pp. 977-987
-
-
Jain, M.K.1
Ridker, P.M.2
-
17
-
-
33749040295
-
Breast cancer growth prevention by statins
-
M. J. Campbell, L. J. Esserman, Y. Zhou, M. Shoemaker, M. Lobo, E. Borman, F. Baehner, A. S. Kumar, K. Adduci, C. Marx, E. F. Petricoin, L. A. Liotta, M. Winters, S. Benz, C. C. Benz, Breast cancer growth prevention by statins. Cancer Res. 66, 8707-8714 (2006).
-
(2006)
Cancer Res.
, vol.66
, pp. 8707-8714
-
-
Campbell, M.J.1
Esserman, L.J.2
Zhou, Y.3
Shoemaker, M.4
Lobo, M.5
Borman, E.6
Baehner, F.7
Kumar, A.S.8
Adduci, K.9
Marx, C.10
Petricoin, E.F.11
Liotta, L.A.12
Winters, M.13
Benz, S.14
Benz, C.C.15
-
18
-
-
34547641739
-
Statin-induced breast cancer cell death: Role of inducible nitric oxide and arginase-dependent pathways
-
S. Kotamraju, C. L. Williams, C. L. Willams, B. Kalyanaraman, Statin-induced breast cancer cell death: Role of inducible nitric oxide and arginase-dependent pathways. Cancer Res. 67, 7386-7394 (2007).
-
(2007)
Cancer Res.
, vol.67
, pp. 7386-7394
-
-
Kotamraju, S.1
Williams, C.L.2
Willams, C.L.3
Kalyanaraman, B.4
-
19
-
-
84877802805
-
Simvastatin attenuates the additive effects of TNF-α and IL-18 on the connexin 43 up-regulation and over-proliferation of cultured aortic smooth muscle cells
-
Y. C. Lin, C. H. Chiang, L. T. Chang, C. K. Sun, S. Leu, P. L. Shao, M. C. Hsieh, T. H. Tsai, S. Chua, S. Y. Chung, Y. H. Kao, H. K. Yip, Simvastatin attenuates the additive effects of TNF-α and IL-18 on the connexin 43 up-regulation and over-proliferation of cultured aortic smooth muscle cells. Cytokine 62, 341-351 (2013).
-
(2013)
Cytokine
, vol.62
, pp. 341-351
-
-
Lin, Y.C.1
Chiang, C.H.2
Chang, L.T.3
Sun, C.K.4
Leu, S.5
Shao, P.L.6
Hsieh, M.C.7
Tsai, T.H.8
Chua, S.9
Chung, S.Y.10
Kao, Y.H.11
Yip, H.K.12
-
20
-
-
20044377927
-
Statins suppress oxidized low density lipoprotein-induced macrophage proliferation by inactivation of the small G protein-p38 MAPK pathway
-
T. Senokuchi, T. Matsumura, M. Sakai, M. Yano, T. Taguchi, T. Matsuo, K. Sonoda, D. Kukidome, K. Imoto, T. Nishikawa, S. Kim-Mitsuyama, Y. Takuwa, E. Araki, Statins suppress oxidized low density lipoprotein-induced macrophage proliferation by inactivation of the small G protein-p38 MAPK pathway. J. Biol. Chem. 280, 6627-6633 (2005).
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 6627-6633
-
-
Senokuchi, T.1
Matsumura, T.2
Sakai, M.3
Yano, M.4
Taguchi, T.5
Matsuo, T.6
Sonoda, K.7
Kukidome, D.8
Imoto, K.9
Nishikawa, T.10
Kim-Mitsuyama, S.11
Takuwa, Y.12
Araki, E.13
-
21
-
-
84892865604
-
A statin-loaded reconstituted high-density lipoprotein nanoparticle inhibits atherosclerotic plaque inflammation
-
R. Duivenvoorden, J. Tang, D. P. Cormode, A. J. Mieszawska, D. Izquierdo-Garcia, C. Ozcan, M. J. Otten, N. Zaidi, M. E. Lobatto, S. M. van Rijs, B. Priem, E. L. Kuan, C. Martel, EJ. Hewing, H. Sager, M. Nahrendorf, G. J. Randolph, E. S. Stroes, V. Fuster, E. A. Fisher, Z. A. Fayad, W. J. Mulder, A statin-loaded reconstituted high-density lipoprotein nanoparticle inhibits atherosclerotic plaque inflammation. Nat. Commun. 5, 3065 (2014).
-
(2014)
Nat. Commun.
, vol.5
, pp. 3065
-
-
Duivenvoorden, R.1
Tang, J.2
Cormode, D.P.3
Mieszawska, A.J.4
Izquierdo-Garcia, D.5
Ozcan, C.6
Otten, M.J.7
Zaidi, N.8
Lobatto, M.E.9
Van Rijs, S.M.10
Priem, B.11
Kuan, E.L.12
Martel, C.13
Hewing, E.J.14
Sager, H.15
Nahrendorf, M.16
Randolph, G.J.17
Stroes, E.S.18
Fuster, V.19
Fisher, E.A.20
Fayad, Z.A.21
Mulder, W.J.22
more..
-
22
-
-
84863903383
-
Myocardial infarction accelerates atherosclerosis
-
P. Dutta, G. Courties, Y. Wei, F. Leuschner, R. Gorbatov, C. S. Robbins, Y. Iwamoto, B. Thompson, A. L. Carlson, T. Heidt, M. D. Majmudar, F. Lasitschka, M. Etzrodt, P. Waterman, M. T. Waring, A. T. Chicoine, A. M. van der Laan, H. W. Niessen, J. J. Piek, B. B. Rubin, J. Butany, J. R. Stone, H. A. Katus, S. A. Murphy, D. A. Morrow, M. S. Sabatine, C. Vinegoni, M. A. Moskowitz, M. J. Pittet, P. Libby, C. P. Lin, F. K. Swirski, R. Weissleder, M. Nahrendorf, Myocardial infarction accelerates atherosclerosis. Nature 487, 325-329 (2012).
-
(2012)
Nature
, vol.487
, pp. 325-329
-
-
Dutta, P.1
Courties, G.2
Wei, Y.3
Leuschner, F.4
Gorbatov, R.5
Robbins, C.S.6
Iwamoto, Y.7
Thompson, B.8
Carlson, A.L.9
Heidt, T.10
Majmudar, M.D.11
Lasitschka, F.12
Etzrodt, M.13
Waterman, P.14
Waring, M.T.15
Chicoine, A.T.16
Laan Der Van, A.M.17
Niessen, H.W.18
Piek, J.J.19
Rubin, B.B.20
Butany, J.21
Stone, J.R.22
Katus, H.A.23
Murphy, S.A.24
Morrow, D.A.25
Sabatine, M.S.26
Vinegoni, C.27
Moskowitz, M.A.28
Pittet, M.J.29
Libby, P.30
Lin, C.P.31
Swirski, F.K.32
Weissleder, R.33
Nahrendorf, M.34
more..
-
23
-
-
84904023285
-
Chronic variable stress activates hematopoietic stem cells
-
T. Heidt, H. B. Sager, G. Courties, P. Dutta, Y. Iwamoto, A. Zaltsman, C. von Zur Muhlen, C. Bode, G. L. Fricchione, J. Denninger, C. P. Lin, C. Vinegoni, P. Libby, F. K. Swirski, R. Weissleder, M. Nahrendorf, Chronic variable stress activates hematopoietic stem cells. Nat. Med. 20, 754-758 (2014).
-
(2014)
Nat. Med.
, vol.20
, pp. 754-758
-
-
Heidt, T.1
Sager, H.B.2
Courties, G.3
Dutta, P.4
Iwamoto, Y.5
Zaltsman, A.6
Muhlen Zur Von, C.7
Bode, C.8
Fricchione, G.L.9
Denninger, J.10
Lin, C.P.11
Vinegoni, C.12
Libby, P.13
Swirski, F.K.14
Weissleder, R.15
Nahrendorf, M.16
-
24
-
-
0013909023
-
Quantitative comparison of toxicity of anticancer agents in mouse, rat, hamster, dog, monkey, and man
-
E. J. Freireich, E. A. Gehan, D. P. Rail, L. H. Schmidt, H. E. Skipper, Quantitative comparison of toxicity of anticancer agents in mouse, rat, hamster, dog, monkey, and man. Cancer Chemother. Rep. 50, 219-244 (1966).
-
(1966)
Cancer Chemother. Rep.
, vol.50
, pp. 219-244
-
-
Freireich, E.J.1
Gehan, E.A.2
Rail, D.P.3
Schmidt, L.H.4
Skipper, H.E.5
-
25
-
-
84864703182
-
Noninvasive magnetic resonance imaging evaluation of endothelial permeability in murine atherosclerosis using an albumin-binding contrast agent
-
A. Phinikaridou, M. E. Andia, A. Protti, A. Indermuehle, A. Shah, A. Smith, A. Warley, R. M. Botnar, Noninvasive magnetic resonance imaging evaluation of endothelial permeability in murine atherosclerosis using an albumin-binding contrast agent. Circulation 126, 707-719 (2012).
-
(2012)
Circulation
, vol.126
, pp. 707-719
-
-
Phinikaridou, A.1
Andia, M.E.2
Protti, A.3
Indermuehle, A.4
Shah, A.5
Smith, A.6
Warley, A.7
Botnar, R.M.8
-
26
-
-
84891674631
-
Noninvasive MRI monitoring of the effect of interventions on endothelial permeability in murine atherosclerosis using an albumin-binding contrast agent
-
A. Phinikaridou, M. E. Andia, G. Passacquale, A. Ferro, R. M. Botnar, Noninvasive MRI monitoring of the effect of interventions on endothelial permeability in murine atherosclerosis using an albumin-binding contrast agent. J. Am. Heart Assoc. 2, e000402 (2013).
-
(2013)
J. Am. Heart Assoc.
, vol.2
, pp. e000402
-
-
Phinikaridou, A.1
Andia, M.E.2
Passacquale, G.3
Ferro, A.4
Botnar, R.M.5
-
27
-
-
84900844706
-
In vivo silencing of the transcription factor IRF5 reprograms the macrophage phenotype and improves infarct healing
-
G. Courties, T. Heidt, M. Sebas, Y. Iwamoto, D. Jeon, J. Truelove, B. Tricot, G. Wojtkiewicz, P. Dutta, H. B. Sager, A. Borodovsky, T. Novobrantseva, B. Klebanov, K. Fitzgerald, D. G. Anderson, P. Libby, F. K. Swirski, R. Weissleder, M. Nahrendorf, In vivo silencing of the transcription factor IRF5 reprograms the macrophage phenotype and improves infarct healing. J. Am. Coll. Cardiol. 63, 1556-1566 (2014).
-
(2014)
J. Am. Coll. Cardiol.
, vol.63
, pp. 1556-1566
-
-
Courties, G.1
Heidt, T.2
Sebas, M.3
Iwamoto, Y.4
Jeon, D.5
Truelove, J.6
Tricot, B.7
Wojtkiewicz, G.8
Dutta, P.9
Sager, H.B.10
Borodovsky, A.11
Novobrantseva, T.12
Klebanov, B.13
Fitzgerald, K.14
Anderson, D.G.15
Libby, P.16
Swirski, F.K.17
Weissleder, R.18
Nahrendorf, M.19
-
28
-
-
79952736069
-
Reversal of hyperlipidemia with a genetic switch favorably affects the content and inflammatory state of macrophages in atherosclerotic plaques
-
J. E. Feig, S. Parathath, J. X. Rong, S. L. Mick, Y. Vengrenyuk, L. Grauer, S. G. Young, E. A. Fisher, Reversal of hyperlipidemia with a genetic switch favorably affects the content and inflammatory state of macrophages in atherosclerotic plaques. Circulation 123, 989-998 (2011).
-
(2011)
Circulation
, vol.123
, pp. 989-998
-
-
Feig, J.E.1
Parathath, S.2
Rong, J.X.3
Mick, S.L.4
Vengrenyuk, Y.5
Grauer, L.6
Young, S.G.7
Fisher, E.A.8
-
29
-
-
78751652694
-
A prospective natural-history study of coronary atherosclerosis
-
G.W. Stone, A. Maehara, A.J. Lansky, B. de Bruyne, E. Cristea,G. S. Mintz, R. Mehran,J. McPherson, N. Farhat, S. P. Marso, H. Parise, B. Templin, R. White, Z. Zhang, P. W. Serruys; PROSPECT Investigators, A prospective natural-history study of coronary atherosclerosis. N. Engl. J. Med. 364, 226-235(2011).
-
(2011)
N. Engl. J. Med.
, vol.364
, pp. 226-235
-
-
Stone, G.W.1
Maehara, A.2
Lansky, A.J.3
De Bruyne, B.4
Cristeag, E.5
Mehran, J.6
McPherson, R.7
Farhat, N.8
Marso, S.P.9
Parise, H.10
Templin, B.11
White, R.12
Zhang, Z.13
Serruys, P.W.14
Investigators, P.15
-
30
-
-
26844447541
-
PROVE IT-TIMI 22 Investigators, Early and late benefits of high-dose atorvastatin in patients with acute coronary syndromes: Results from the PROVE IT-TIMI 22 trial
-
K. K. Ray, C. P. Cannon, C. H. McCabe, R. Cairns, A. M. Tonkin, F. M. Sacks, G. Jackson, E. Braunwald; PROVE IT-TIMI 22 Investigators, Early and late benefits of high-dose atorvastatin in patients with acute coronary syndromes: Results from the PROVE IT-TIMI 22 trial. J. Am. Coll. Cardiol. 46, 1405-1410 (2005).
-
(2005)
J. Am. Coll. Cardiol.
, vol.46
, pp. 1405-1410
-
-
Ray, K.K.1
Cannon, C.P.2
McCabe, C.H.3
Cairns, R.4
Tonkin, A.M.5
Sacks, F.M.6
Jackson, G.7
Braunwald, E.8
-
31
-
-
84883379072
-
Increased systemic and local interleukin 9 levels in patients with carotid and coronary atherosclerosis
-
I. Gregersen, M. Skjelland, S. Holm, K. B. Holven, K. Krogh-Sorensen, D. Russell, E. T. Askevold, C. P. Dahl, S. Orn, L. Gullestad, T. E. Mollnes, T. Ueland, P. Aukrust, B. Halvorsen, Increased systemic and local interleukin 9 levels in patients with carotid and coronary atherosclerosis. PLOS One 8, e72769 (2013).
-
(2013)
PLOS One
, vol.8
, pp. e72769
-
-
Gregersen, I.1
Skjelland, M.2
Holm, S.3
Holven, K.B.4
Krogh-Sorensen, K.5
Russell, D.6
Askevold, E.T.7
Dahl, C.P.8
Orn, S.9
Gullestad, L.10
Mollnes, T.E.11
Ueland, T.12
Aukrust, P.13
Halvorsen, B.14
-
32
-
-
0025120211
-
Regulation of the mevalonate pathway
-
J. L. Goldstein, M. S. Brown, Regulation of the mevalonate pathway. Nature 343, 425-430 (1990).
-
(1990)
Nature
, vol.343
, pp. 425-430
-
-
Goldstein, J.L.1
Brown, M.S.2
-
33
-
-
33646354412
-
Statin therapy and autoimmune disease: From protein prenylation to immunomodulation
-
J. Greenwood, L. Steinman, S. S. Zamvil, Statin therapy and autoimmune disease: From protein prenylation to immunomodulation. Nat. Rev. Immunol. 6, 358-370 (2006).
-
(2006)
Nat. Rev. Immunol.
, vol.6
, pp. 358-370
-
-
Greenwood, J.1
Steinman, L.2
Zamvil, S.S.3
-
34
-
-
28844490054
-
Statins and cancer prevention
-
M.-F. Demierre, P. D. R. Higgins, S. B. Gruber, E. Hawk, S. M. Lippman, Statins and cancer prevention. Nat. Rev. Cancer 5, 930-942 (2005).
-
(2005)
Nat. Rev. Cancer
, vol.5
, pp. 930-942
-
-
Demierre, M.-F.1
Higgins, P.D.R.2
Gruber, S.B.3
Hawk, E.4
Lippman, S.M.5
-
35
-
-
84896707657
-
Nanoparticle-mediated delivery of pravastatin inhibits atherosclerotic plaque destabilization/rupture in mice by regulating the recruitment of inflammatory monocytes
-
S. Katsuki, T. Matoba, S. Nakashiro, K. Sato, J. Koga, K. Nakano, Y. Nakano, S. Egusa, K. Sunagawa, K. Egashira, Nanoparticle-mediated delivery of pravastatin inhibits atherosclerotic plaque destabilization/rupture in mice by regulating the recruitment of inflammatory monocytes. Circulation 129, 896-906 (2014).
-
(2014)
Circulation
, vol.129
, pp. 896-906
-
-
Katsuki, S.1
Matoba, T.2
Nakashiro, S.3
Sato, K.4
Koga, J.5
Nakano, K.6
Nakano, Y.7
Egusa, S.8
Sunagawa, K.9
Egashira, K.10
-
36
-
-
12244297142
-
Simvastatin reduces NF-kB activity in peripheral mononuclear and in plaque cells of rabbit atheroma more markedly than lipid lowering diet
-
M. A. Hernandez-Presa, M. Ortego, J. Tuhon, J. L. Martfn-Ventura, S. Mas, L. M. Blanco-Colio, C. Aparicio, L. Ortega, J. Gomez-Gerique, F. Vivanco, J. Egido, Simvastatin reduces NF-kB activity in peripheral mononuclear and in plaque cells of rabbit atheroma more markedly than lipid lowering diet. Cardiovasc. Res. 57, 168-177 (2003).
-
(2003)
Cardiovasc. Res.
, vol.57
, pp. 168-177
-
-
Hernandez-Presa, M.A.1
Ortego, M.2
Tuhon, J.3
Martfn-Ventura, J.L.4
Mas, S.5
Blanco-Colio, L.M.6
Aparicio, C.7
Ortega, L.8
Gomez-Gerique, J.9
Vivanco, F.10
Egido, J.11
-
37
-
-
0035895319
-
An HMG-CoA reductase inhibitor, cerivastatin, suppresses growth of macrophages expressing matrix metalloproteinases and tissue factor in vivo and in vitro
-
M. Aikawa, E. Rabkin, S. Sugiyama, S.J. Voglic, Y. Fukumoto, Y. Furukawa, M. Shiomi, F.J. Schoen, P. Libby, An HMG-CoA reductase inhibitor, cerivastatin, suppresses growth of macrophages expressing matrix metalloproteinases and tissue factor in vivo and in vitro. Circulation 103, 276-283 (2001).
-
(2001)
Circulation
, vol.103
, pp. 276-283
-
-
Aikawa, M.1
Rabkin, E.2
Sugiyama, S.J.3
Voglic, S.4
Fukumoto, Y.5
Furukawa, M.6
Shiomi, Y.7
Schoen, F.J.8
Libby, P.9
-
38
-
-
58149314526
-
Nanocrystal core high-density lipoproteins: A multimodality contrast agent platform
-
D. P. Cormode, T.Skajaa, M. M. van Schooneveld, R. Koole, P. Jarzyna, M. E. Lobatto, C. Calcagno, A. Barazza, R. E. Gordon, P. Zanzonico, E. A. Fisher, Z. A. Fayad, W. J. Mulder, Nanocrystal core high-density lipoproteins: A multimodality contrast agent platform. Nano Lett. 8, 3715-3723 (2008).
-
(2008)
Nano Lett.
, vol.8
, pp. 3715-3723
-
-
Cormode, D.P.1
Skajaa, T.2
Van Schooneveld, M.M.3
Koole, R.4
Jarzyna, P.5
Lobatto, M.E.6
Calcagno, C.7
Barazza, A.8
Gordon, R.E.9
Zanzonico, P.10
Fisher, E.A.11
Fayad, Z.A.12
Mulder, W.J.13
-
39
-
-
84888880335
-
Single step reconstitution of multifunctional high-density i i pop rote in -derived nanomaterials using microfluidics
-
Y. Kim, F. Fay, D. P. Cormode, B. L. Sanchez-Gaytan, J. Tang, E. J. Hennessy, M. Ma, K. Moore, O. C. Farokhzad, E. A. Fisher, W. J. Mulder, R. Langer, Z. A. Fayad, Single step reconstitution of multifunctional high-density I i pop rote in -derived nanomaterials using microfluidics. ACS Nano 7, 9975-9983 (2013).
-
(2013)
ACS Nano
, vol.7
, pp. 9975-9983
-
-
Kim, Y.1
Fay, F.2
Cormode, D.P.3
Sanchez-Gaytan, B.L.4
Tang, J.5
Hennessy, E.J.6
Ma, M.7
Moore, K.8
Farokhzad, O.C.9
Fisher, E.A.10
Mulder, W.J.11
Langer, R.12
Fayad, Z.A.13
-
40
-
-
66349090172
-
High-relaxivity gadolinium-modified high-density lipoproteins as magnetic resonance imaging contrast agents
-
K. C. Briley-Saebo, S. Geninatti-Crich, D. P. Cormode, A. Barazza, W. J. Mulder, W. Chen, G. B. Giovenzana, E. A. Fisher, S. Aime, Z. A. Fayad, High-relaxivity gadolinium-modified high-density lipoproteins as magnetic resonance imaging contrast agents. J. Phys. Chem. B 113, 6283-6289 (2009).
-
(2009)
J. Phys. Chem. B
, vol.113
, pp. 6283-6289
-
-
Briley-Saebo, K.C.1
Geninatti-Crich, S.2
Cormode, D.P.3
Barazza, A.4
Mulder, W.J.5
Chen, W.6
Giovenzana, G.B.7
Fisher, E.A.8
Aime, S.9
Fayad, Z.A.10
-
41
-
-
84899863296
-
Myeloid cell microsomal prostaglandin e synthase-1 fosters atherogenesis in mice
-
L. Chen, G. Yang, J. Monslow, L. Todd, D. P. Cormode, J. Tang, G. R. Grant, J. H. DeLong, S. Y. Tang, J. A. Lawson, E. Pure, G. A. Fitzgerald, Myeloid cell microsomal prostaglandin E synthase-1 fosters atherogenesis in mice. Proc. Natl. Acad. Sci. U.S.A. 111, 6828-6833 (2014).
-
(2014)
Proc. Natl. Acad. Sci. U.S.A.
, vol.111
, pp. 6828-6833
-
-
Chen, L.1
Yang, G.2
Monslow, J.3
Todd, L.4
Cormode, D.P.5
Tang, J.6
Grant, G.R.7
DeLong, J.H.8
Tang, S.Y.9
Lawson, J.A.10
Pure, E.11
Fitzgerald, G.A.12
-
42
-
-
0035954267
-
High-dose recombinant apolipoprotein A-lMMano mobilizes tissue cholesterol and rapidly reduces plaque lipid and macrophage content in apolipoprotein E-deficient mice. Potential implications for acute plaque stabilization
-
P. K. Shah, J. Yano, O. Reyes, K. Y. Chyu, S. Kaul, C. L. Bisgaier, S. Drake, B. Cercek, High-dose recombinant apolipoprotein A-lMMano mobilizes tissue cholesterol and rapidly reduces plaque lipid and macrophage content in apolipoprotein E-deficient mice. Potential implications for acute plaque stabilization. Circulation 103, 3047-3050 (2001).
-
(2001)
Circulation
, vol.103
, pp. 3047-3050
-
-
Shah, P.K.1
Yano, J.2
Reyes, O.3
Chyu, K.Y.4
Kaul, S.5
Bisgaier, C.L.6
Drake, S.7
Cercek, B.8
-
43
-
-
0242577955
-
Effect of recombinant ApoA-l Milano on coronary atherosclerosis in patients with acute coronary syndromes: A randomized controlled trial
-
S. E. Nissen, T. Tsunoda, E. M. Tuzcu, P. Schoenhagen, C. J. Cooper, M. Yasin, G. M. Eaton, M.A. Lauer, W.S.Sheldon, C. L. Grines,S. Halpern, T. Crowe, J. C. Blankenship, R. Kerensky, Effect of recombinant ApoA-l Milano on coronary atherosclerosis in patients with acute coronary syndromes: A randomized controlled trial. JAMA 290, 2292-2300 (2003).
-
(2003)
JAMA
, vol.290
, pp. 2292-2300
-
-
Nissen, S.E.1
Tsunoda, T.2
Tuzcu, E.M.3
Schoenhagen, P.4
Cooper, C.J.5
Yasin, M.6
Eaton, G.M.7
Lauer, M.A.8
Sheldon, W.S.9
Grines, C.L.10
Halpern, S.11
Crowe, T.12
Blankenship, J.C.13
Kerensky, R.14
-
44
-
-
34247397359
-
Effect of rHDL on Atherosclerosis-Safety and Efficacy (ERASE) Investigators, Effects of reconstituted high-density lipoprotein infusions on coronary atherosclerosis: A randomized controlled trial
-
J. C. Tardif, J. Gregoire, P. L. L'Allier, R. Ibrahim, J. Lesperance, T. M. Heinonen, S. Kouz, C. Berry, R. Basser, M. A. Lavoie, M. C. Guertin, J. Rodes-Cabau; Effect of rHDL on Atherosclerosis-Safety and Efficacy (ERASE) Investigators, Effects of reconstituted high-density lipoprotein infusions on coronary atherosclerosis: A randomized controlled trial. JAMA 297, 1675-1682 (2007).
-
(2007)
JAMA
, vol.297
, pp. 1675-1682
-
-
Tardif, J.C.1
Gregoire, J.2
L'Allier, P.L.3
Ibrahim, R.4
Lesperance, J.5
Heinonen, T.M.6
Kouz, S.7
Berry, C.8
Basser, R.9
Lavoie, M.A.10
Guertin, M.C.11
Rodes-Cabau, J.12
-
45
-
-
84906242912
-
HDL and cardiovascular disease
-
D. J. Rader, G. K. Hovingh, HDL and cardiovascular disease. Lancet 384, 618-625 (2014).
-
(2014)
Lancet
, vol.384
, pp. 618-625
-
-
Rader, D.J.1
Hovingh, G.K.2
-
46
-
-
84899109502
-
ST elevation acute myocardial infarction accelerates non-culprit coronary lesion atherosclerosis
-
Y. Han, J. Jing, S. Tu, F. Tian, H. Xue, W. Chen, J. Chen, J. H. Reiber, Y. Chen, ST elevation acute myocardial infarction accelerates non-culprit coronary lesion atherosclerosis. Int. J. Cardiovasc. Imaging 30, 253-261 (2014).
-
(2014)
Int. J. Cardiovasc. Imaging
, vol.30
, pp. 253-261
-
-
Han, Y.1
Jing, J.2
Tu, S.3
Tian, F.4
Xue, H.5
Chen, W.6
Chen, J.7
Reiber, J.H.8
Chen, Y.9
-
47
-
-
0027740243
-
Human atherosclerosis. IV. Immuno-cytochemical analysis of cell activation and proliferation in lesions of young adults
-
S. Katsuda, M. D. Coltrera, R. Ross, A. M. Gown, Human atherosclerosis. IV. Immuno-cytochemical analysis of cell activation and proliferation in lesions of young adults. Am. J. Pathol. 142, 1787-1793 (1993).
-
(1993)
Am. J. Pathol.
, vol.142
, pp. 1787-1793
-
-
Katsuda, S.1
Coltrera, M.D.2
Ross, R.3
Gown, A.M.4
-
48
-
-
0028978776
-
Active proliferation of different cell types, including lymphocytes, in human atherosclerotic plaques
-
M. D. Rekhter, D. Gordon, Active proliferation of different cell types, including lymphocytes, in human atherosclerotic plaques. Am. J. Pathol. 147, 668-677 (1995).
-
(1995)
Am. J. Pathol.
, vol.147
, pp. 668-677
-
-
Rekhter, M.D.1
Gordon, D.2
-
49
-
-
0033019113
-
Biphasic pattern of cell turnover characterizes the progression from fatty streaks to ruptured human atherosclerotic plaques
-
E. Lutgens, E. D. de Muinck, P. J. Kitslaar, J. H. Tordoir, H. J. Wellens, M. J. Daemen, Biphasic pattern of cell turnover characterizes the progression from fatty streaks to ruptured human atherosclerotic plaques. Cardiovasc. Res. 41, 473-479 (1999).
-
(1999)
Cardiovasc. Res.
, vol.41
, pp. 473-479
-
-
Lutgens, E.1
De Muinck, E.D.2
Kitslaar, P.J.3
Tordoir, J.H.4
Wellens, H.J.5
Daemen, M.J.6
-
50
-
-
84907558689
-
A modular labeling strategy for in vivo PET and near-infrared fluorescence imaging of nanoparticle tumor targeting
-
C. Perez-Medina, D. Abdel-Atti, Y. Zhang, V. A. Longo, C. P. Irwin, T. Binderup, J. Ruiz-Cabello, Z. A. Fayad, J. S. Lewis, W.J. Mulder, T. Reiner, A modular labeling strategy for in vivo PET and near-infrared fluorescence imaging of nanoparticle tumor targeting. J. Nucl. Med. 55,1706-1711 (2014).
-
(2014)
J. Nucl. Med.
, vol.55
, pp. 1706-1711
-
-
Perez-Medina, C.1
Abdel-Atti, D.2
Zhang, Y.3
Longo, V.A.4
Irwin, C.P.5
Binderup, T.6
Ruiz-Cabello, J.7
Fayad, Z.A.8
Lewis, J.S.9
Mulder, W.J.10
Reiner, T.11
-
51
-
-
84885290802
-
Mortality from ischaemic heart disease by country, region, and age: Statistics from World Health Organisation and
-
United Nations
-
J. A. Finegold, P. Asaria, D. P. Francis, Mortality from ischaemic heart disease by country, region, and age: Statistics from World Health Organisation and United Nations. Int. J. Cardiol. 168, 934-945 (2013).
-
(2013)
Int. J. Cardiol.
, vol.168
, pp. 934-945
-
-
Finegold, J.A.1
Asaria, P.2
Francis, D.P.3
|