Chemical characterization, toxicology and mechanism of gastric antiulcer action of essential oil from Gallesia integrifolia (Spreng.) Harms in the in vitro and in vivo experimental models

Biomedicine and Pharmacotherapy

Volumn 94, Issue , 2017, Pages 292-306

  Arunachalam, Karuppusamy ^a   Balogun, Sikiru Olaitan ^a,b   Pavan, Eduarda ^a   de Almeida, Guilherme Vieira Botelho ^a   de Oliveira, Ruberlei Godinho ^a   Wagner, Theodoro ^c   Cechinel Filho, Valdir ^c   de Oliveira Martins, Domingos Tabajara ^a  

^a FEDERAL UNIVERSITY OF MATO GROSSO   (Brazil)

^b Faculdade de Ciências Médicas e da Saúde de Juiz de Fora Suprema   (Brazil)

^c UNIVERSIDADE DO VALE DO ITAJAÍ   (Brazil)

Author keywords

Essential oil; Gallesia integrifolia; Gastric ulcer; Phytochemical analysis; Toxicity

Indexed keywords

ACETIC ACID; ACETYLCYSTEINE; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; ALCOHOL; ALPHA SANTALENE; ANTIULCER AGENT; CARBENOXOLONE; CATALASE; CIMETIDINE; ESSENTIAL OIL; GALLESIA INTEGRIFOLIA EXTRACT; INDOMETACIN; INTERLEUKIN 10; INTERLEUKIN 1BETA; MYELOPEROXIDASE; NITRIC OXIDE; NITRITE; OMEPRAZOLE; PIROXICAM; PLANT EXTRACT; PROSTAGLANDIN; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ACIDITY; ACUTE TOXICITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ANTIULCER ACTIVITY; ARTICLE; BARK; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; DRUG SAFETY; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; GALLESIA INTEGRIFOLIA; GENOTOXICITY; HELICOBACTER PYLORI; IN VITRO STUDY; IN VIVO STUDY; MALE; MASS FRAGMENTOGRAPHY; MEDICINAL PLANT; MOUSE; NONHUMAN; PHYTOCHEMISTRY; PLANT STEM; PRIORITY JOURNAL; STOMACH MUCUS; STOMACH PH; STOMACH PROTECTION; STOMACH SECRETION; STOMACH ULCER; STOMACH VOLUME; TOXICITY TESTING; ULCER HEALING; ANIMAL; CELL SURVIVAL; CHEMISTRY; CHO CELL LINE; CRICETULUS; DISEASE MODEL; DRUG EFFECT; MICROBIAL SENSITIVITY TEST; MICRONUCLEUS TEST; PHYTOLACCACEAE; RAT; STOMACH MUCOSA;

ANIMALS; ANTI-ULCER AGENTS; CELL SURVIVAL; CHO CELLS; CRICETULUS; DISEASE MODELS, ANIMAL; FEMALE; GASTRIC MUCOSA; HELICOBACTER PYLORI; MALE; MICE; MICROBIAL SENSITIVITY TESTS; MICRONUCLEUS TESTS; OILS, VOLATILE; PHYTOLACCACEAE; PLANT BARK; RATS; STOMACH ULCER; TOXICITY TESTS, ACUTE;

EID: 85026423113     PISSN: 07533322     EISSN: 19506007     Source Type: Journal    
DOI: 10.1016/j.biopha.2017.07.064     Document Type: Article

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