Evaluation of acute toxicity, antibacterial activity, and mode of action of the hydroethanolic extract of Piper umbellatum L

Journal of Ethnopharmacology

Volumn 151, Issue 1, 2014, Pages 137-143

  Da Silva, Iberê Ferreira ^a   De Oliveira, Ruberlei Godinho ^a   Mendes Soares, Ilsamar ^b   Da Costa Alvim, Tarso ^b   Donizeti Ascêncio, Sérgio ^b   De Oliveira Martins, Domingos Tabajara ^a  

^a FEDERAL UNIVERSITY OF MATO GROSSO   (Brazil)

^b UNIVERSIDADE FEDERAL DO TOCANTINS   (Brazil)

Author keywords

Antibacterial activity; Flavonoids; Hydroethanolic extract; Mode of action; Piper umbellatum

Indexed keywords

ALCOHOL; ANTIINFECTIVE AGENT; PIPER UMBELLATUM EXTRACT; PLANT EXTRACT; UNCLASSIFIED DRUG;

ACUTE TOXICITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL STRAIN; BROTH DILUTION; CYTOTOXICITY ASSAY; DRUG MECHANISM; ENTEROCOCCUS FAECALIS; ESCHERICHIA COLI; EVALUATION STUDY; IC 50; IN VITRO STUDY; KLEBSIELLA PNEUMONIAE; MALE; MEDICINAL PLANT; MOUSE; NONHUMAN; PHYTOCHEMISTRY; PIPER (PLANT); PIPER UMBELLATUM; PSEUDOMONAS AERUGINOSA; SALMONELLA TYPHIMURIUM; SHIGELLA FLEXNERI; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS; STREPTOCOCCUS PYOGENES;

BACTERIA (MICROORGANISMS); MUS; PIPER UMBELLATUM; PIPERACEAE;

ANTIBACTERIAL ACTIVITY; FLAVONOIDS; HYDROETHANOLIC EXTRACT; MODE OF ACTION; PIPER UMBELLATUM;

ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIA; CHO CELLS; CRICETINAE; CRICETULUS; ETHANOL; MALE; MICE; MICROBIAL SENSITIVITY TESTS; PIPER; PLANT EXTRACTS; POTASSIUM; WATER;

EID: 84891492863     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2013.10.011     Document Type: Article

References (28)

1. G.A. Agbor, J.A. Vinson, J. Sortino, and R. Johnson Antioxidant and anti-atherogenic activities of three Piper species on atherogenic diet fed hamsters Exp. Toxicol. Pathol. 64 2012 387 391
2. C.Z. Chen, and S.L. Cooper Interactions between dendrimer biocides and bacterial membranes Biomaterials 23 2002 3359 3368
3. CLSI Clinical and Laboratory Standards Institute, formely NCCLS (National Committee for Clinical Laboratory Standards) Methods for diluition antimicrobial susceptibility test for bacteria that grow aerobically; Approved Standard-NCCLS document M7-A6 6 ed. 2003 Wayne Pennsylvania USA
4. T.P.T. Cushnie, and A.J. Lamb Recent advances in understanding the antibacterial properties of flavonoids Int. J. Antimicrob. Agents 38 2011 99 107
5. T.P.T Cushnie, and A.J. Lamb Antimicrobial activity of flavonoids Int. J. Antimicrob. Agents 26 2005 343 356
6. A.R. Da Silva, S.M. de Morais, M.M. Marques, D.F. de Oliveira, C.C. Barros, R.R. de Almeida, Í.G. Vieira, and M.I. Guedes Chemical composition, antioxidant and antibacterial activities of two Spondias species from Northeastern Brazil Pharm. Biol. 50 2012 740 746
7. B.O. Froelich, A. Kakooko, K. Siems, C. Schubert, and K. Jenett-Siems Plants traditionally used against malaria: phytochemical and pharmacological investigation of Momordica foetida Braz. J. Pharmacogn. 17 2007 1 7
8. G. Hao, Y-H. Shi, Y-L. Tang, and G-W. Le The membrane action mechanism of analogs of the antimicrobial peptide Buforin 2 Peptides 30 2009 1421 1427
9. T. Isobe, K. Ohsaki, and K. Nagaka Antibacterial constituents against Helicobacter pylori of Brazilian medicinal plant, Pariparoba Yakugaku Zasshi 122 2002 291 294
10. K. Kamanzi Atindehou, C. Schmid, R. Brun, M.W. Koné, and D. Traore Antitrypanosomal and antiplasmodial activity of medicinal plants from Côte d'Ivoire J. Ethnopharmacol. 90 2004 221 227
11. A.L. Koch Bacterial wall as target for attack: past, present, and future research Clin. Microbiol. Rev. 16 2003 673 687
12. V. Kuete Potential of Cameroonian plants and derived products against microbial infections: a review Planta Medica 76 2010 1479 1491
13. Z. Lou, H. Wang, S. Zhu, C. Ma, and Z. Wang Antibacterial activity and mechanism of action of chlorogenic acid J. Food Sci. 76 2011 M398 M403
14. G.B. Mahady Medicinal plants for the prevention and treatment of bacterial infections Curr. Pharm. Design 11 2005 2405 2427
15. M.H. Malone, and R.C. Robichaud A hippocratic screen for pure or crude drug materials Lloyd 25 1962 320 332
16. Matos, F.J.A., 1997. Introdução à fitoquímica experimental. 2. ed. Fortaleza. Imprensa Universitária, UFC. 139 p.
17. T.J.S. Peixoto Sobrinho, C.H.T.P. Silva, J.E. Nascimento, J.M. Monteiro, U.P. Albuquerque, and E.L.C. Amorim Validação de metodologia espectrofotométrica para quantificação dos flavonóides de Bauhinia cheilantha (Bongard) Steudel Braz. J. Pharm. Sci. 44 2008 683 689
18. F.F. Perazzo, G.H.B. Souza, W. Lopes, L.G.V. Cardoso, J.C.T. Carvalho, N.P.D. Nanayakkara, and J.K. Bastos Antiinflammatory and analgesic properties of waterethanolic extract from Pothomorphe umbellata (Piperaceae) aerial parts J. Ethnopharmacol. 99 2005 215 220
19. C.M. Roersch Piper umbellatum L.: a comparative cross-cultural analysis of its medicinal uses and an ethnopharmacological evaluation J. Ethnopharmacol. 131 2010 522 537
20. J.L. Sacoman, K.M. Monteiro, A. Possenti, G.M. Figueira, M.A. Foglio, and J.E. Carvalho Cytotoxicity and antitumoral activity of dichloromethane extract and its fractions from Pothomorphe umbellata Braz. J. Med. Biol. Res. 41 2008 411 415
21. D. Savoia Plant-derived antimicrobial compounds: alternatives to antibiotics Future Microbiol. 8 2012 979 990
22. J.E. Springer, R.D. Azbill, and S.L. Carlson A rapid and sensitive assay for measuring mitochondrial metabolic activity in isolated neural tissue Brain Res. Protoc. 2 1998 259 263
23. T.K. Tabopda, A.C. Mitaine-Offer, T. Miyamoto, C. Tanaka, B.T. Ngadjuic, and M.A. Lacaille-Dubois Secondary metabolites from polar fractions of Piper umbellatum Nat. Product Commun. 7 2012 595 596
24. Y-L. Tang, Y-H. Shi, W. Zhao, G. Hao, and G-W. Le Insertion mode of a novel anionic antimicrobial peptide MDpep5 (Val-Glu-Ser-Trp-Val) from Chinese traditional edible larvae of housefly and its effect on surface potential of bacterial membrane J. Pharm. Biomed. Anal. 48 2008 1187 1194
25. P. Viljanen, H. Matsunaga, Y. Kimura, and M. Vaara The outer membrane permeability-increasing action of deacyl-polymyxins J. Antibiot. 44 1991 517 523
26. J.S. Werka, A.K. Boehme, and W.N. Setzer Biological activities of essential oils from Monteverde, Costa Rica Nat. Product Commun. 2 2007 1215 1219
27. S.M. Yi, J.L. Zhu, L.L. Fu, and J.R. Li Tea polyphenols inhibit Pseudomonas aeruginosa through damage to the cell membrane Int. J. Food Microbiol. 144 2010 111 117
28. L. Zhang, A.S. Ravipati, S.R. Koyyalamudi, S.C. Jeong, N. Reddy, J. Bartlett, P.T. Smith, M. de la Cruz, M.C. Monteiro, A. Melguizo, E. Jiménez, and F. Vicente Anti-fungal and anti-bacterial activities of ethanol extracts of selected traditional Chinese medicinal herbs Asian Pac. J. Trop. Med. 6 2013 673 681