메뉴 건너뛰기




Volumn 101, Issue , 2017, Pages 36-47

A subchronic 90-day oral toxicity study of Origanum vulgare essential oil in rats

Author keywords

90 Day oral; Oregano essential oil; Rats; Subchronic toxicity

Indexed keywords

ESSENTIAL OIL; ORIGANUM VULGARE ESSENTIAL OIL; UNCLASSIFIED DRUG;

EID: 85009110146     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2017.01.001     Document Type: Article
Times cited : (43)

References (61)
  • 2
    • 79960076841 scopus 로고    scopus 로고
    • The effects of carvacrol on apoptosis of H-ras and N-ras transformed cell lines
    • Akalin, G., Incesu, Z., The effects of carvacrol on apoptosis of H-ras and N-ras transformed cell lines. Turk. J. Pharm. Sci. 8:2 (2011), 105–116.
    • (2011) Turk. J. Pharm. Sci. , vol.8 , Issue.2 , pp. 105-116
    • Akalin, G.1    Incesu, Z.2
  • 3
    • 77952291439 scopus 로고    scopus 로고
    • Anti-proliferative effects of carvacrol on a human metastatic breast cancer cell line, MDA-MB231
    • Arunasree, K.M., Anti-proliferative effects of carvacrol on a human metastatic breast cancer cell line, MDA-MB231. Phytomedicine 17 (2010), 581–588.
    • (2010) Phytomedicine , vol.17 , pp. 581-588
    • Arunasree, K.M.1
  • 4
    • 84922311321 scopus 로고    scopus 로고
    • Quality preservation of organic cottage cheese using oregano essential oils
    • Asensio, C.M., Grosso, N.R., Juliani, H.R., Quality preservation of organic cottage cheese using oregano essential oils. LWT - Food Sci. Technol. 60 (2015), 664–671.
    • (2015) LWT - Food Sci. Technol. , vol.60 , pp. 664-671
    • Asensio, C.M.1    Grosso, N.R.2    Juliani, H.R.3
  • 5
    • 13844297555 scopus 로고    scopus 로고
    • The effects of thyme volatiles on the induction of DNA damage by the heterocyclic amine IQ and mitomycin C
    • Aydin, S., Basaran, A.A., Basaran, N., The effects of thyme volatiles on the induction of DNA damage by the heterocyclic amine IQ and mitomycin C. Mutat. Res. 581 (2005), 43–53.
    • (2005) Mutat. Res. , vol.581 , pp. 43-53
    • Aydin, S.1    Basaran, A.A.2    Basaran, N.3
  • 6
    • 13944259305 scopus 로고    scopus 로고
    • Modulating effects of thyme and its major ingredients on oxidative DNA damage in human lymphocytes
    • Aydin, S., Basaran, A.A., Basaran, N., Modulating effects of thyme and its major ingredients on oxidative DNA damage in human lymphocytes. J. Agric. Food Chem. 53 (2005), 1299–1305.
    • (2005) J. Agric. Food Chem. , vol.53 , pp. 1299-1305
    • Aydin, S.1    Basaran, A.A.2    Basaran, N.3
  • 7
    • 84893676329 scopus 로고    scopus 로고
    • The effect of carvacrol on healthy neurons and N2a cancer cells: some biochemical: anticancerogenicity and genotoxicity studies
    • Aydin, E., Türkez, H., Keles, M.S., The effect of carvacrol on healthy neurons and N2a cancer cells: some biochemical: anticancerogenicity and genotoxicity studies. Cytotechnology 66 (2014), 149–157.
    • (2014) Cytotechnology , vol.66 , pp. 149-157
    • Aydin, E.1    Türkez, H.2    Keles, M.S.3
  • 8
    • 0028890761 scopus 로고
    • Mutagenicity and antimutagenicity testing of six chemicals associated with the pungent properties of specific spices as revealed by the Ames Salmonella/microsomal assay
    • Azizan, A., Blevins, R.D., Mutagenicity and antimutagenicity testing of six chemicals associated with the pungent properties of specific spices as revealed by the Ames Salmonella/microsomal assay. Arch. Environ. Contam. Toxicol. 28 (1995), 248–258.
    • (1995) Arch. Environ. Contam. Toxicol. , vol.28 , pp. 248-258
    • Azizan, A.1    Blevins, R.D.2
  • 9
    • 84860194125 scopus 로고    scopus 로고
    • Assessment of anti-angiogenic and anti-tumoral potentials of Origanum onites L. essential oil
    • Bostancioglu, R.B., Kürkçüoglu, M., Baser, K.H.C., Koparal, A.T., Assessment of anti-angiogenic and anti-tumoral potentials of Origanum onites L. essential oil. Food Chem. Toxicol. 50 (2012), 2002–2008.
    • (2012) Food Chem. Toxicol. , vol.50 , pp. 2002-2008
    • Bostancioglu, R.B.1    Kürkçüoglu, M.2    Baser, K.H.C.3    Koparal, A.T.4
  • 10
    • 0016469166 scopus 로고
    • Toxicology and biochemistry of butylated hydroxyanisole and butylated hydroxytoluene
    • Branen, A.L., Toxicology and biochemistry of butylated hydroxyanisole and butylated hydroxytoluene. J. Am. Oil Chem. Soc. 52 (1974), 59–62.
    • (1974) J. Am. Oil Chem. Soc. , vol.52 , pp. 59-62
    • Branen, A.L.1
  • 11
    • 3042838374 scopus 로고    scopus 로고
    • Essential oils: their antibacterial properties and potential applications in food- a review
    • Burt, S., Essential oils: their antibacterial properties and potential applications in food- a review. Int. J. Food Microbiol. 94 (2004), 223–253.
    • (2004) Int. J. Food Microbiol. , vol.94 , pp. 223-253
    • Burt, S.1
  • 12
    • 59149103608 scopus 로고    scopus 로고
    • The effects of thymol on sister chromatid exchange, chromosome aberration and micronucleus in human lymphocytes
    • Buyukleyla, M., Rencuzogullari, E., The effects of thymol on sister chromatid exchange, chromosome aberration and micronucleus in human lymphocytes. Ecotox. Environ. Safe 72 (2009), 943–947.
    • (2009) Ecotox. Environ. Safe , vol.72 , pp. 943-947
    • Buyukleyla, M.1    Rencuzogullari, E.2
  • 13
    • 79151470577 scopus 로고    scopus 로고
    • Display life of beef packaged with an antioxidant active film as a function of the concentration of oregano extract
    • Camo, J., Lorés, A., Djenane, D., Beltrán, J.A., Roncalés, P., Display life of beef packaged with an antioxidant active film as a function of the concentration of oregano extract. Meat Sci. 88 (2011), 174–178.
    • (2011) Meat Sci. , vol.88 , pp. 174-178
    • Camo, J.1    Lorés, A.2    Djenane, D.3    Beltrán, J.A.4    Roncalés, P.5
  • 15
    • 79960300756 scopus 로고    scopus 로고
    • No 450/2009 of 29 May 2009 on active and intelligent materials and articles intended to come into contact with food
    • Commission Regulation (EC) No 450/2009 of 29 May 2009 on active and intelligent materials and articles intended to come into contact with food. Official Journal of the European Union, L 135/3-L 135-145.
    • Official Journal of the European Union , vol.L 135 , Issue.3-L , pp. 135-145
    • Commission Regulation (EC)1
  • 16
    • 85009131510 scopus 로고    scopus 로고
    • Commission Implementing Decision of 14 November 2012 establishing a common format for the submission of the information pursuant to Directive 2010/63/EU
    • Decision 2012/707/UE. Commission Implementing Decision of 14 November 2012 establishing a common format for the submission of the information pursuant to Directive 2010/63/EU of the European Parliament and of the Council on the protection of animals used for scientific purposes. http://ec.europa.eu/environment/chemicals/lab_animals/pdf/Unofficial%20Consolidated%20version.pdf (Accessed 23 November 2016).
    • (2016) European Parliament and of the Council on the protection of animals used for scientific purposes
    • Decision 2012/707/UE1
  • 17
    • 84934942505 scopus 로고    scopus 로고
    • Efficacy of the combined application of oregano and rosemary essential oils for the control of Escherichia coli, Listeria monocytogenes and Salmonella enteritidis in leafy vegetables
    • de Medeiros Barbosa, I.M., Medeiros, J.A.C., de Oliveira, K.A.R., Gomes-Neto, N.J., Tavares, J.F., Magnani, M., de Souza, E.L., Efficacy of the combined application of oregano and rosemary essential oils for the control of Escherichia coli, Listeria monocytogenes and Salmonella enteritidis in leafy vegetables. Food control. 59 (2016), 468–477.
    • (2016) Food control. , vol.59 , pp. 468-477
    • de Medeiros Barbosa, I.M.1    Medeiros, J.A.C.2    de Oliveira, K.A.R.3    Gomes-Neto, N.J.4    Tavares, J.F.5    Magnani, M.6    de Souza, E.L.7
  • 19
    • 33749550685 scopus 로고    scopus 로고
    • Essential oils-their antimicrobial activity against Escherichia coli and effect on intestinal cell viability
    • Dusan, F., Marián, S., Katarína, D., Dobroslava, B., Essential oils-their antimicrobial activity against Escherichia coli and effect on intestinal cell viability. Toxicol. Vitro 20 (2006), 1435–1445.
    • (2006) Toxicol. Vitro , vol.20 , pp. 1435-1445
    • Dusan, F.1    Marián, S.2    Katarína, D.3    Dobroslava, B.4
  • 21
    • 80053103602 scopus 로고    scopus 로고
    • Guidance Document on the Submission of a Dossier on a Substance to Be Used in Food Contact Materials for Evaluation by EFSA by the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (AFC)
    • (Accessed 23 November 2016)
    • European Food Safety Authority, Guidance Document on the Submission of a Dossier on a Substance to Be Used in Food Contact Materials for Evaluation by EFSA by the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (AFC). 2008 (Accessed 23 November 2016) http://www.efsa.europa.eu/en/efsajournal/doc/21r.pdf.
    • (2008)
    • European Food Safety Authority1
  • 23
    • 78751705774 scopus 로고    scopus 로고
    • Antibacterial activity of oregano and thyme essential oils against Listeria monocytogenes and Escherichia coli O157:H7 in feta cheese packaged under modified atmosphere
    • Govaris, A., Botsoglou, E., Sergelidis, D., Chatzopoulou, P.S., Antibacterial activity of oregano and thyme essential oils against Listeria monocytogenes and Escherichia coli O157:H7 in feta cheese packaged under modified atmosphere. LWT - Food Sci. Technol. 44 (2011), 1240–1244.
    • (2011) LWT - Food Sci. Technol. , vol.44 , pp. 1240-1244
    • Govaris, A.1    Botsoglou, E.2    Sergelidis, D.3    Chatzopoulou, P.S.4
  • 24
    • 34047232955 scopus 로고    scopus 로고
    • Study of cytotoxic, genotoxic and DNA-protective effects of selected plant essential oils on human cells cultured in vitro
    • Horvathova, E., Sramkova, M., Labaj, J., Slamenova, D., Study of cytotoxic, genotoxic and DNA-protective effects of selected plant essential oils on human cells cultured in vitro. Neuro. Endocrinol. Lett. 27 (2006), 44–47.
    • (2006) Neuro. Endocrinol. Lett. , vol.27 , pp. 44-47
    • Horvathova, E.1    Sramkova, M.2    Labaj, J.3    Slamenova, D.4
  • 25
    • 84888876845 scopus 로고    scopus 로고
    • Essential oils as potential antimicrobial agents in meat and meat products: a review
    • Jayasena, D.D., Jo, C., Essential oils as potential antimicrobial agents in meat and meat products: a review. Trends Food Sci. Technol. 34 (2013), 96–108.
    • (2013) Trends Food Sci. Technol. , vol.34 , pp. 96-108
    • Jayasena, D.D.1    Jo, C.2
  • 26
    • 84856911883 scopus 로고    scopus 로고
    • A preliminary 13-week oral toxicity study of ginger oil in male and female wistar rats
    • Jeena, K., Liju, V.B., Kuttan, R., A preliminary 13-week oral toxicity study of ginger oil in male and female wistar rats. Int. J. Toxicol. 30 (2014), 662–670.
    • (2014) Int. J. Toxicol. , vol.30 , pp. 662-670
    • Jeena, K.1    Liju, V.B.2    Kuttan, R.3
  • 27
    • 23944493825 scopus 로고    scopus 로고
    • Effects of carvacrol on a human non-small cell lung cancer (NSCLC) cell line, A549
    • Koparal, A.T., Zeytinoglu, M., Effects of carvacrol on a human non-small cell lung cancer (NSCLC) cell line, A549. Cytotechnology 43 (2003), 149–154.
    • (2003) Cytotechnology , vol.43 , pp. 149-154
    • Koparal, A.T.1    Zeytinoglu, M.2
  • 29
    • 84905243673 scopus 로고    scopus 로고
    • Evaluation of the mutagenicity and genotoxic potential of carvacrol and thymol using the Ames Salmonella test and alkaline, Endo III and FPG-modified comet assays with the human cell line Caco-2
    • Llana-Ruiz-Cabello, M., Maisanaba, S., Puerto, M., Prieto, A.I., Pichardo, S., Jos, A., Cameán, A.M., Evaluation of the mutagenicity and genotoxic potential of carvacrol and thymol using the Ames Salmonella test and alkaline, Endo III and FPG-modified comet assays with the human cell line Caco-2. Food Chem. Toxicol. 72 (2014), 122–128.
    • (2014) Food Chem. Toxicol. , vol.72 , pp. 122-128
    • Llana-Ruiz-Cabello, M.1    Maisanaba, S.2    Puerto, M.3    Prieto, A.I.4    Pichardo, S.5    Jos, A.6    Cameán, A.M.7
  • 34
    • 84871464088 scopus 로고    scopus 로고
    • Acute and subchronic toxicity as well as mutagenic evaluation of essential oil from turmeric (Curcuma longa L)
    • Liju, V.B., Jeena, K., Kuttan, R., Acute and subchronic toxicity as well as mutagenic evaluation of essential oil from turmeric (Curcuma longa L). Food Chem. Toxicol. 53 (2013), 52–61.
    • (2013) Food Chem. Toxicol. , vol.53 , pp. 52-61
    • Liju, V.B.1    Jeena, K.2    Kuttan, R.3
  • 35
    • 84930274628 scopus 로고    scopus 로고
    • In vitro genotoxicity testing of carvacrol and thymol using the micronucleus and mouse lymphoma assays
    • Maisanaba, S., Prieto, A.I., Puerto, M., Gutiérrez-Praena, D., Demir, E., Marcos, R., Cameán, A.M., In vitro genotoxicity testing of carvacrol and thymol using the micronucleus and mouse lymphoma assays. Mutat. Res. 784–785 (2015), 37–44.
    • (2015) Mutat. Res. , vol.784-785 , pp. 37-44
    • Maisanaba, S.1    Prieto, A.I.2    Puerto, M.3    Gutiérrez-Praena, D.4    Demir, E.5    Marcos, R.6    Cameán, A.M.7
  • 36
    • 84903851004 scopus 로고    scopus 로고
    • Influence of pH and temperature on vapor phase action of an antifungal food packaging against five mold strains
    • Manso, S., Becerril, R., Nerín, C., Gómez-Lus, R., Influence of pH and temperature on vapor phase action of an antifungal food packaging against five mold strains. Food Control 47 (2015), 20–26.
    • (2015) Food Control , vol.47 , pp. 20-26
    • Manso, S.1    Becerril, R.2    Nerín, C.3    Gómez-Lus, R.4
  • 37
    • 84927711958 scopus 로고    scopus 로고
    • Oregano and lavender essential oils as antioxidant and antimicrobial additives of biogenic gelatin films
    • Martucci, J.F., Gende, L.B., Neira, L.M., Ruseckaite, R.A., Oregano and lavender essential oils as antioxidant and antimicrobial additives of biogenic gelatin films. Ind. Crop. Prod. 71 (2015), 205–213.
    • (2015) Ind. Crop. Prod. , vol.71 , pp. 205-213
    • Martucci, J.F.1    Gende, L.B.2    Neira, L.M.3    Ruseckaite, R.A.4
  • 39
    • 84908374910 scopus 로고    scopus 로고
    • Antioxidant and antimicrobial properties of ethylene vinyl alcohol copolymer films based on the release of oregano essential oil and Green tea extract components
    • Muriel-Galet, V., Cran, M.J., Bigger, S.W., Hernández-Muñoz, P., Gavara, R., Antioxidant and antimicrobial properties of ethylene vinyl alcohol copolymer films based on the release of oregano essential oil and Green tea extract components. J. Food Eng. 149 (2015), 9–16.
    • (2015) J. Food Eng. , vol.149 , pp. 9-16
    • Muriel-Galet, V.1    Cran, M.J.2    Bigger, S.W.3    Hernández-Muñoz, P.4    Gavara, R.5
  • 40
    • 33750436549 scopus 로고    scopus 로고
    • Stabilization of beef meat by a new active packaging containing natural antioxidants
    • Nerín, C., Tovar, L., Djenane, D., Camo, J., Salafranca, J., Beltrán, J.A., Stabilization of beef meat by a new active packaging containing natural antioxidants. J. Agr. Food Chem. 54 (2006), 7840–7846.
    • (2006) J. Agr. Food Chem. , vol.54 , pp. 7840-7846
    • Nerín, C.1    Tovar, L.2    Djenane, D.3    Camo, J.4    Salafranca, J.5    Beltrán, J.A.6
  • 43
    • 0141957276 scopus 로고    scopus 로고
    • A subchronic 90-day oral rat toxicity study and in vitro genotoxicity studies with a conjugated linoleic acid product
    • O'Hagan, S., Menzel, A., A subchronic 90-day oral rat toxicity study and in vitro genotoxicity studies with a conjugated linoleic acid product. Food Chem. Toxicol. 41 (2003), 1749–1760.
    • (2003) Food Chem. Toxicol. , vol.41 , pp. 1749-1760
    • O'Hagan, S.1    Menzel, A.2
  • 44
    • 80855164674 scopus 로고    scopus 로고
    • Comparative evaluation of antioxidant and anticancer activity of essential oil from Origanum onites (Lamiaceae) and its two major phenolic components
    • Özkan, A., Erdogan, A.A., Comparative evaluation of antioxidant and anticancer activity of essential oil from Origanum onites (Lamiaceae) and its two major phenolic components. Turk. J. Biol. 35 (2011), 735–742.
    • (2011) Turk. J. Biol. , vol.35 , pp. 735-742
    • Özkan, A.1    Erdogan, A.A.2
  • 45
    • 84959875446 scopus 로고    scopus 로고
    • Effects of dietary supplementation with oregano essential oil on growth performance, carcass traits and jejunal morphology in broiler chickens
    • Peng, Q.Y., Li, J.D., Li, Z., Duan, Z.Y., Wu, Y.P., Effects of dietary supplementation with oregano essential oil on growth performance, carcass traits and jejunal morphology in broiler chickens. Anim. Feed Sci. Technol. 214 (2016), 148–153.
    • (2016) Anim. Feed Sci. Technol. , vol.214 , pp. 148-153
    • Peng, Q.Y.1    Li, J.D.2    Li, Z.3    Duan, Z.Y.4    Wu, Y.P.5
  • 47
    • 80051740908 scopus 로고    scopus 로고
    • Safety and toxicological evaluation of a synthetic vitamin K2, menaquinone-7
    • Pucaj, K., Rasmussen, H., Moller, M., Preston, T., Safety and toxicological evaluation of a synthetic vitamin K2, menaquinone-7. Toxicol. Mech. Methods 21 (2011), 520–532.
    • (2011) Toxicol. Mech. Methods , vol.21 , pp. 520-532
    • Pucaj, K.1    Rasmussen, H.2    Moller, M.3    Preston, T.4
  • 49
    • 84913534180 scopus 로고    scopus 로고
    • Dietary effects of a mix derived from oregano (Origanum vulgare L.) essential oil and sweet chestnut (Castanea sativa Mill.) wood extract on pig performance, oxidative status and pork quality traits
    • Ranucci, D., Beghelli, D., Trabalza-Marinucci, M., Branciari, R., Forte, C., Olivieri, O., Badillo Pazmay, G.V., Cavallucci, C., Acuti, G., Dietary effects of a mix derived from oregano (Origanum vulgare L.) essential oil and sweet chestnut (Castanea sativa Mill.) wood extract on pig performance, oxidative status and pork quality traits. Meat Sci. 100 (2015), 319–326.
    • (2015) Meat Sci. , vol.100 , pp. 319-326
    • Ranucci, D.1    Beghelli, D.2    Trabalza-Marinucci, M.3    Branciari, R.4    Forte, C.5    Olivieri, O.6    Badillo Pazmay, G.V.7    Cavallucci, C.8    Acuti, G.9
  • 50
    • 85009063224 scopus 로고    scopus 로고
    • Real Decreto, se establecen las normas básicas aplicables para la protección de los animales utilizados en experimentación y otros fines científicos, incluyendo la docencia
    • 11370e11421 (Accessed 23 November 2016)
    • RD 53/2013, Real Decreto, se establecen las normas básicas aplicables para la protección de los animales utilizados en experimentación y otros fines científicos, incluyendo la docencia. 11370e11421 BOE, 34, 2013 http://boe.es/boe/dias/2013/02/08/pdfs/BOE-A-2013-1337.pdf (Accessed 23 November 2016).
    • (2013) BOE , vol.34
    • RD 53/20131
  • 51
    • 67649409380 scopus 로고    scopus 로고
    • Origanum vulgare induces apoptosis in human colon cancer Caco2 cells
    • Savini, I., Arnone, R., Catani, M.V., Avigliano, L., Origanum vulgare induces apoptosis in human colon cancer Caco2 cells. Nutr. Cancer 61 (2009), 381–389.
    • (2009) Nutr. Cancer , vol.61 , pp. 381-389
    • Savini, I.1    Arnone, R.2    Catani, M.V.3    Avigliano, L.4
  • 52
    • 57049154547 scopus 로고    scopus 로고
    • The effect of dietary oregano essential oil on microbial growth of rabbit carcasses during refrigerated storage
    • Soultos, N., Tzikas, Z., Christaki, E., Papageorgiou, K., Steris, V., The effect of dietary oregano essential oil on microbial growth of rabbit carcasses during refrigerated storage. Meat Sci. 81 (2009), 474–478.
    • (2009) Meat Sci. , vol.81 , pp. 474-478
    • Soultos, N.1    Tzikas, Z.2    Christaki, E.3    Papageorgiou, K.4    Steris, V.5
  • 54
    • 68649096335 scopus 로고    scopus 로고
    • Antioxidant activities of major thyme ingredients and lack of (oxidative) DNA damage in V79 Chinese hamster lung fibroblast cells at low levels of carvacrol and thymol
    • Ündeger, U., Basaran, A., Degen, G.H., Basaran, N., Antioxidant activities of major thyme ingredients and lack of (oxidative) DNA damage in V79 Chinese hamster lung fibroblast cells at low levels of carvacrol and thymol. Food Chem. Toxicol. 47 (2009), 2037–2043.
    • (2009) Food Chem. Toxicol. , vol.47 , pp. 2037-2043
    • Ündeger, U.1    Basaran, A.2    Degen, G.H.3    Basaran, N.4
  • 55
    • 84962519021 scopus 로고    scopus 로고
    • The effect of cinnamon, oregano and thyme essential oils in marinade on the microbial shelf life of fish and meat products
    • Van Haute, S., Raes, K., Van der Meeren, P., Sampers, I., The effect of cinnamon, oregano and thyme essential oils in marinade on the microbial shelf life of fish and meat products. Food control. 68 (2016), 30–39.
    • (2016) Food control. , vol.68 , pp. 30-39
    • Van Haute, S.1    Raes, K.2    Van der Meeren, P.3    Sampers, I.4
  • 56
    • 84962886255 scopus 로고    scopus 로고
    • Safety assessment of a standardized polyphenolic extract of clovebuds: subchronic toxicity and mutagenicity studies
    • Vijayasteltara, L., Nair, G.G., Maliakel, B., Kuttana, R., Krishnakumar, I.M., Safety assessment of a standardized polyphenolic extract of clovebuds: subchronic toxicity and mutagenicity studies. Toxicol. Rep. 3 (2016), 439–449.
    • (2016) Toxicol. Rep. , vol.3 , pp. 439-449
    • Vijayasteltara, L.1    Nair, G.G.2    Maliakel, B.3    Kuttana, R.4    Krishnakumar, I.M.5
  • 57
    • 84946497454 scopus 로고    scopus 로고
    • Oregano essential oil decreased susceptibility to oxidative stress-induced dysfunction of intestinal epithelial barrier in rats
    • Wei, H.K., Chen, G., Wang, R.J., Peng, J., Oregano essential oil decreased susceptibility to oxidative stress-induced dysfunction of intestinal epithelial barrier in rats. J. Funct. Foods 18 (2016), 1191–1199.
    • (2016) J. Funct. Foods , vol.18 , pp. 1191-1199
    • Wei, H.K.1    Chen, G.2    Wang, R.J.3    Peng, J.4
  • 58
    • 84655163356 scopus 로고    scopus 로고
    • Anti-proliferative and pro-apoptotic effect of carvacrol on human hepatocellular carcinoma cell line HepG-2
    • Yin, Q.H., Yan, F.X., Zu, X.Y., Wu, Y.U., Wu, X.P., Liao, M.C., Deng, S.W., Yin, L.I., Zhuang, Y.Z., Anti-proliferative and pro-apoptotic effect of carvacrol on human hepatocellular carcinoma cell line HepG-2. Cytotechnology 64 (2012), 43–51.
    • (2012) Cytotechnology , vol.64 , pp. 43-51
    • Yin, Q.H.1    Yan, F.X.2    Zu, X.Y.3    Wu, Y.U.4    Wu, X.P.5    Liao, M.C.6    Deng, S.W.7    Yin, L.I.8    Zhuang, Y.Z.9
  • 59
    • 84920399894 scopus 로고    scopus 로고
    • A 90-day study of three bruchid-resistant mung bean cultivars in Sprague-Dawley rats
    • Yao, Y., Cheng, X., Ren, G., A 90-day study of three bruchid-resistant mung bean cultivars in Sprague-Dawley rats. Food Chem. Toxicol. 76 (2015), 80–85.
    • (2015) Food Chem. Toxicol. , vol.76 , pp. 80-85
    • Yao, Y.1    Cheng, X.2    Ren, G.3
  • 60
    • 84941893792 scopus 로고    scopus 로고
    • Effects of dietary oregano essential oil supplementation on the stress response, antioxidative capacity, and HSPs mRNA expression of transported pigs
    • Zhang, T., Zhou, Y.F., Zou, Y., Hu, X.M., Zheng, L.F., Wei, H.K., Giannenas, I., Jin, L.Z., Peng, J., Jiang, S.W., Effects of dietary oregano essential oil supplementation on the stress response, antioxidative capacity, and HSPs mRNA expression of transported pigs. Livest. Sci. 180 (2015), 143–149.
    • (2015) Livest. Sci. , vol.180 , pp. 143-149
    • Zhang, T.1    Zhou, Y.F.2    Zou, Y.3    Hu, X.M.4    Zheng, L.F.5    Wei, H.K.6    Giannenas, I.7    Jin, L.Z.8    Peng, J.9    Jiang, S.W.10
  • 61
    • 84945491191 scopus 로고    scopus 로고
    • A 90-day subchronic study of rats fed lean pork from genetically modified pigs with muscle-specific expression of recombinant follistatin. Regul. Toxicol
    • Zou, S., Tang, M., He, X., Cao, Y., Zhao, J., Xu, W., Liang, Z., Huang, K., A 90-day subchronic study of rats fed lean pork from genetically modified pigs with muscle-specific expression of recombinant follistatin. Regul. Toxicol. Pharm 73 (2015), 620–628.
    • (2015) Pharm , vol.73 , pp. 620-628
    • Zou, S.1    Tang, M.2    He, X.3    Cao, Y.4    Zhao, J.5    Xu, W.6    Liang, Z.7    Huang, K.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.