Conformational Changes of CFTR upon Phosphorylation and ATP Binding

Cell

Volumn 170, Issue 3, 2017, Pages 483-491.e8

  Zhang, Zhe ^a,b   Liu, Fangyu ^a   Chen, Jue ^a,b  

^a ROCKEFELLER UNIVERSITY   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

ABC transporter; anion channel; ATP bound; CFTR; cryo EM; phosphorylated form

Indexed keywords

ADENOSINE TRIPHOSPHATE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; CFTR PROTEIN, ZEBRAFISH; ZEBRAFISH PROTEIN;

ANIMAL CELL; ARTICLE; CHANNEL GATING; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYOELECTRON MICROSCOPY; CYTOPLASM; INTRACELLULAR TRANSPORT; MEMBRANE TRANSPORT; NONHUMAN; NUCLEOTIDE BINDING SITE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; ZEBRA FISH; AMINO ACID SEQUENCE; CHEMISTRY; HUMAN; METABOLISM; MOLECULAR MODEL; SEQUENCE ALIGNMENT;

ADENOSINE TRIPHOSPHATE; AMINO ACID SEQUENCE; CRYOELECTRON MICROSCOPY; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; HUMANS; MODELS, MOLECULAR; PROTEIN DOMAINS; SEQUENCE ALIGNMENT; ZEBRAFISH PROTEINS;

EID: 85026400698     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2017.06.041     Document Type: Article

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