-
1
-
-
0037013262
-
The first nucleotide binding domain of cystic fibrosis transmembrane conductance regulator is a site of stable nucleotide interaction, whereas the second is a site of rapid turnover
-
DOI 10.1074/jbc.M111713200
-
Aleksandrov, L., A.A. Aleksandrov, X.B. Chang, and J.R. Riordan. 2002. The first nucleotide binding domain of cystic fibrosis transmembrane conductance regulator is a site of stable nucleotide interaction, whereas the second is a site of rapid turnover. J. Biol. Chem. 277:15419-15425. doi:10.1074/jbc. M111713200 (Pubitemid 34967805)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.18
, pp. 15419-15425
-
-
Aleksandrov, L.1
Aleksandrov, A.A.2
Chang, X.-B.3
Riordan, J.R.4
-
2
-
-
56049099012
-
Mg2+-dependent ATP occlusion at the first nucleotide-binding domain (NBD1) of CFTR does not require the second (NBD2)
-
doi:10.1042/BJ20081068
-
Aleksandrov, L., A. Aleksandrov, and J.R. Riordan. 2008. Mg2+-dependent ATP occlusion at the first nucleotide-binding domain (NBD1) of CFTR does not require the second (NBD2). Biochem. J. 416:129-136. doi:10.1042/BJ20081068
-
(2008)
Biochem. J.
, vol.416
, pp. 129-136
-
-
Aleksandrov, L.1
Aleksandrov, A.2
Riordan, J.R.3
-
3
-
-
63449139456
-
Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding
-
doi:10.1126/ science. 1168750
-
Aller, S.G., J. Yu, A. Ward, Y. Weng, S. Chittaboina, R. Zhuo, P.M. Harrell, Y.T. Trinh, Q. Zhang, I.L. Urbatsch, and G. Chang. 2009. Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding. Science. 323:1718-1722. doi:10.1126/ science. 1168750
-
(2009)
Science.
, vol.323
, pp. 1718-1722
-
-
Aller, S.G.1
Yu, J.2
Ward, A.3
Weng, Y.4
Chittaboina, S.5
Zhuo, R.6
Harrell, P.M.7
Trinh, Y.T.8
Zhang, Q.9
Urbatsch, I.L.10
Chang, G.11
-
4
-
-
0025931429
-
Nucleoside triphosphates are required to open the CFTR chloride channel
-
doi: 10.1016/ 0092-8674(91)90072-90077
-
Anderson, M.P., H.A. Berger, D.P. Rich, R.J. Gregory, A.E. Smith, and M.J. Welsh. 1991. Nucleoside triphosphates are required to open the CFTR chloride channel. Cell. 67:775-784. doi: 10.1016/ 0092-8674(91)90072-90077
-
(1991)
Cell.
, vol.67
, pp. 775-784
-
-
Anderson, M.P.1
Berger, H.A.2
Rich, D.P.3
Gregory, R.J.4
Smith, A.E.5
Welsh, M.J.6
-
5
-
-
0141513675
-
2-terminal nucleotide binding domain and its role in channel gating
-
doi:10.1085/jgp.200308798
-
2-terminal nucleotide binding domain and its role in channel gating. J. Gen. Physiol. 122:333-348. doi:10.1085/jgp.200308798
-
(2003)
J. Gen. Physiol.
, vol.122
, pp. 333-348
-
-
Basso, C.1
Vergani, P.2
Nairn, A.C.3
Gadsby, D.C.4
-
6
-
-
0026532895
-
Purification and functional reconstitution of the cystic fibrosis transmembrane conductance regulator (CFTR)
-
doi: 10.1016/0092-8674 (92)90155-90156
-
Bear, C.E., C.H. Li, N. Kartner, R.J. Bridges, T.J. Jensen, M. Ramjeesingh, and J.R. Riordan. 1992. Purification and functional reconstitution of the cystic fibrosis transmembrane conductance regulator (CFTR). Cell. 68:809-818. doi: 10.1016/0092-8674 (92)90155-90156
-
(1992)
Cell.
, vol.68
, pp. 809-818
-
-
Bear, C.E.1
Li, C.H.2
Kartner, N.3
Bridges, R.J.4
Jensen, T.J.5
Ramjeesingh, M.6
Riordan, J.R.7
-
7
-
-
17044383747
-
CFTR gating I: Characterization of the ATP-dependent gating of a phosphorylation-independent CFTR channel (ΔR-CFTR)
-
DOI 10.1085/jgp.200409227
-
Bompadre, S.G., T. Ai, J.H. Cho, X. Wang, Y. Sohma, M. Li, and T.C. Hwang. 2005. CFTR gating I. Characterization of the ATP-dependent gating of a phosphorylation-independent CFTR channel (ΔR-CFTR). J. Gen. Physiol. 125:361-375. doi: 10.1085/ jgp.200409227 (Pubitemid 40504129)
-
(2005)
Journal of General Physiology
, vol.125
, Issue.4
, pp. 361-375
-
-
Bompadre, S.G.1
Ai, T.2
Cho, J.H.3
Wang, X.4
Sohma, Y.5
Li, M.6
Hwang, T.-C.7
-
8
-
-
33947725805
-
G551D and G1349D, two CF-associated mutations in the signature sequences of CFTR, exhibit. distinct gating defects
-
doi:10.1085/jgp.200609667
-
Bompadre, S.G., Y. Sohma, M. Li, and T.C. Hwang. 2007. G551D and G1349D, two CF-associated mutations in the signature sequences of CFTR, exhibit. distinct gating defects. J. Gen. Physiol 129:285-298. doi:10.1085/jgp.200609667
-
(2007)
J. Gen. Physiol
, vol.129
, pp. 285-298
-
-
Bompadre, S.G.1
Sohma, Y.2
Li, M.3
Hwang, T.C.4
-
9
-
-
41949115564
-
Mechanism of G551D-CFTR (cystic fibrosis transmembrane conductance regulator) potentiation by a high affinity ATP analog
-
doi:10.1074/jbc.M709417200
-
Bompadre, S.G., M. Li, and T.C. Hwang. 2008. Mechanism of G551D-CFTR (cystic fibrosis transmembrane conductance regulator) potentiation by a high affinity ATP analog. J. Biol. Chem. 283:5364-5369. doi:10.1074/jbc.M709417200
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 5364-5369
-
-
Bompadre, S.G.1
Li, M.2
Hwang, T.C.3
-
10
-
-
0141527345
-
A tweezers-like motion of the ATP-binding cassette dimer in an ABC transport cycle
-
DOI 10.1016/j.molcel.2003.08.004
-
Chen, J., G. Lu, J. Lin, A.L. Davidson, and F.A. Quiocho. 2003. A tweezers-like motion of the ATP-binding cassette dimer in an ABC transport cycle. Mol. Cell. 12:651-661. doi:10.1016/ j.molcel.2003.08.004 (Pubitemid 37222486)
-
(2003)
Molecular Cell
, vol.12
, Issue.3
, pp. 651-661
-
-
Chen, J.1
Lu, G.2
Lin, J.3
Davidson, A.L.4
Quiocho, F.A.5
-
11
-
-
42049096734
-
CLC-0 and CFTR: Chloride channels evolved from transporters
-
doi: 10.1152/physrev.00058.2006
-
Chen, T.Y., and T.C. Hwang. 2008. CLC-0 and CFTR: chloride channels evolved from transporters. Physiol. Rev. 88:351-387. doi: 10.1152/physrev.00058. 2006
-
(2008)
Physiol. Rev.
, vol.88
, pp. 351-387
-
-
Chen, T.Y.1
Hwang, T.C.2
-
12
-
-
17144456826
-
Rapid kinetic analysis of multichannel records by a simultaneous fit to all dwell-time histograms
-
Csanády, L. 2000. Rapid kinetic analysis of multichannel records by a simultaneous fit to all dwell-time histograms. Biophys. J. 78:785799. doi: 10.1016/S0006-3495 (00)76636-76637 (Pubitemid 30211836)
-
(2000)
Biophysical Journal
, vol.78
, Issue.2
, pp. 785-799
-
-
Csanady, L.1
-
13
-
-
3943062954
-
ATP-binding cassette transport ers in bacteria
-
doi:10.1146/ annurev.biochem. 73.011303.073626
-
Davidson, A.L., and J. Chen. 2004. ATP-binding cassette transport ers in bacteria. Annu. Rev. Biochem. 73:241-268. doi:10.1146/ annurev.biochem. 73.011303.073626
-
(2004)
Annu. Rev. Biochem.
, vol.73
, pp. 241-268
-
-
Davidson, A.L.1
Chen, J.2
-
14
-
-
44949249999
-
Structure, function, and evolution of bacterial ATP-binding cassette systems
-
doi:10.1128/MMBR.00031-07
-
Davidson, A.L., E. Dassa, C. Orelle, and J. Chen. 2008. Structure, function, and evolution of bacterial ATP-binding cassette systems. Microbiol. Mol. Biol. Rev. 72:317-364, doi:10.1128/MMBR.00031-07
-
(2008)
Microbiol. Mol. Biol. Rev.
, vol.72
, pp. 317-364
-
-
Davidson, A.L.1
Dassa, E.2
Orelle, C.3
Chen, J.4
-
15
-
-
33645307384
-
The ABC protein turned chloride channel whose failure causes cystic fibrosis
-
doi:10.1038/nature04712
-
Gadsby, D.C., P. Vergani, and L. Csanády. 2006. The ABC protein turned chloride channel whose failure causes cystic fibrosis. Nature. 440:477-483. doi:10.1038/nature04712
-
(2006)
Nature.
, vol.440
, pp. 477-483
-
-
Gadsby, D.C.1
Vergani, P.2
Csanády, L.3
-
16
-
-
0034724680
-
Comparison of the functional characteristics of the nucleotide binding domains of Multidrug Resistance Protein 1
-
DOI 10.1074/jbc.275.17.13098
-
Gao, M., H.R. Cui, D.W. Loe, C.E. Grant, K.C. Almquist, S.P. Cole, and R.G. Deeley. 2000. Comparison of the functional characteristics of the nucleotide binding domains of multidrug resistance protein 1. J. Biol. Chem. 275:13098-13108. doi:10.1074/ jbc.275.17.13098 (Pubitemid 30241472)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.17
, pp. 13098-13108
-
-
Gao, M.1
Cui, H.-R.2
Loe, D.W.3
Grant, C.E.4
Almquist, K.C.5
Cole, S.P.C.6
Deeley, R.G.7
-
17
-
-
34548853133
-
Structure and mechanism of ABC transporter proteins
-
DOI 10.1016/j.sbi.2007.07.003, PII S0959440X07001029
-
Hollenstein, K., R.J. Dawson, and K.P. Locher. 2007. Structure and mechanism of ABC transporter proteins. Curr. Opin. Struct. Biol. 17:412-418. doi:10.1016/j.sbi.2007.07.003 (Pubitemid 47451766)
-
(2007)
Current Opinion in Structural Biology
, vol.17
, Issue.4
, pp. 412-418
-
-
Hollenstein, K.1
Dawson, R.J.2
Locher, K.P.3
-
18
-
-
0034617097
-
Allosteric interactions between the two non-equivalent nucleotide binding domains of multidrug resistance protein MRP1
-
DOI 10.1074/jbc.M001109200
-
Hou, Y., L. Cui, J.R. Riordan, and X. Chang. 2000. Allosteric interactions between the two non-equivalent nucleotide binding domains of multidrug resistance protein MRP1. J. Biol. Chem. 275:20280-20287. doi:10.1074/jbc.M001109200 (Pubitemid 30457601)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.27
, pp. 20280-20287
-
-
Hou, Y.-X.1
Cui, L.2
Riordan, J.R.3
Chang, X.-B.4
-
19
-
-
0038711772
-
The ATP hydrolysis cycle of the nucleotide-binding domain of the mitochondrial ATP-binding cassette transporter Mdl1p
-
doi: 10.1074/ jbc.M301227200
-
Janas, E., M. Hofacker, M. Chen, S. Gompf, C. van der Does, and R. lampé. 2003. The ATP hydrolysis cycle of the nucleotide-binding domain of the mitochondrial ATP-binding cassette transporter Mdl1p. J. Biol. Chem. 278:26862-26869. doi: 10.1074/ jbc.M301227200
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 26862-26869
-
-
Janas, E.1
Hofacker, M.2
Chen, M.3
Gompf, S.4
Van Der Does, C.5
Lampé, R.6
-
20
-
-
0014029736
-
Simple allosteric model for membrane pumps
-
doi:10.1038/211969a0
-
Jardetzky, O. 1966. Simple allosteric model for membrane pumps. Nature. 211:969-970. doi:10.1038/211969a0
-
(1966)
Nature
, vol.211
, pp. 969-970
-
-
Jardetzky, O.1
-
21
-
-
66149139241
-
Opening of the ADP-bound active site in the ABC transporter ATPase dimer: Evidence for a constant contact, alternating sites model for the catalytic cycle
-
doi:10.1002/prot.22250
-
Jones, P.M., and A.M. George. 2009. Opening of the ADP-bound active site in the ABC transporter ATPase dimer: evidence for a constant contact, alternating sites model for the catalytic cycle. Proteins. 75:387-396. doi:10.1002/prot.22250
-
(2009)
Proteins.
, vol.75
, pp. 387-396
-
-
Jones, P.M.1
George, A.M.2
-
22
-
-
0034941969
-
Crystal structures of the MJ1267 ATP binding cassette reveal an induced-fit effect at the ATPase active site of an ABC transporter
-
DOI 10.1016/S0969-2126(01)00617-7, PII S0969212601006177
-
Karpowich, N., O. Martsinkevich, L. Millen, Y.R. Yuan, P.L. Dai, K. MacVey, P.J. Thomas, and J.F. Hunt. 2001. Crystal structures of the MJ1267 ATP binding cassette reveal an induced-fit effect at the ATPase active site of an ABC transporter. Structure. 9:571-586. doi:10.1016/S0969-2126(01)00617-7 (Pubitemid 32695582)
-
(2001)
Structure
, vol.9
, Issue.7
, pp. 571-586
-
-
Karpowich, N.1
Martsinkevich, O.2
Millen, L.3
Yuan, Y.-R.4
Dai, P.L.5
MacVey, K.6
Thomas, P.J.7
Hunt, J.F.8
-
23
-
-
60549097035
-
Alternating access in maltose transporter mediated by rigid-body rotations
-
doi:10.1016/j.molcel .2009.01.035
-
Khare, D., M.L. Oldham, C. Orelle, A.L. Davidson, and J. Chen. 2009. Alternating access in maltose transporter mediated by rigid-body rotations. Mol. Cell 33:528-536. doi:10.1016/j.molcel .2009.01.035
-
(2009)
Mol. Cell
, vol.33
, pp. 528-536
-
-
Khare, D.1
Oldham, M.L.2
Orelle, C.3
Davidson, A.L.4
Chen, J.5
-
24
-
-
10744230777
-
Structure of nucleotide-binding domain 1 of the cystic fibrosis transmembrane conductance regulator
-
doi: 10.1038/sj.emboj.7600040
-
Lewis, H.A., S.G. Buchanan, S.K. Burley, K. Conners, M. Dickey, M. Dorwart, R. Fowler, X. Gao, W.B. Guggino, W.A. Hendrickson, et. al. 2004. Structure of nucleotide-binding domain 1 of the cystic fibrosis transmembrane conductance regulator. EMBO J. 23:282-293. doi: 10.1038/sj.emboj.7600040
-
(2004)
EMBO J.
, vol.23
, pp. 282-293
-
-
Lewis, H.A.1
Buchanan, S.G.2
Burley, S.K.3
Conners, K.4
Dickey, M.5
Dorwart, M.6
Fowler, R.7
Gao, X.8
Guggino, W.B.9
Hendrickson, W.A.10
-
25
-
-
19944432524
-
Impact of the deltaF508 mutation in first nucleotide-binding domain of human cystic fibrosis transmembrane conductance regulator on domain folding and structure
-
doi:10.1074/jbc.M410968200
-
Lewis, H.A., X. Zhao, C. Wang, J.M. Sauder, I. Rooney, B.W. Noland, D. Lorimer, M.C. Kearins, K. Conners, B. Condon, et al. 2005. Impact of the deltaF508 mutation in first nucleotide-binding domain of human cystic fibrosis transmembrane conductance regulator on domain folding and structure. J. Biol. Chem. 280: 1346-1353. doi:10.1074/jbc.M410968200
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 1346-1353
-
-
Lewis, H.A.1
Zhao, X.2
Wang, C.3
Sauder, J.M.4
Rooney, I.5
Noland, B.W.6
Lorimer, D.7
Kearins, M.C.8
Conners, K.9
Condon, B.10
-
26
-
-
29144502288
-
ATP hydrolysis is required to reset the ATP-binding cassette dimer into the resting-state conformation
-
DOI 10.1073/pnas.0506039102
-
Lu, G., J.M. Westbrooks, A.L. Davidson, and J. Chen. 2005. ATP hydrolysis is required to reset the ATP-binding cassette dimer into the resting-state conformation. Proc. Natl. Acad. Sci. USA. 102:17969-17974, doi: 10.1073/pnas.0506039102 (Pubitemid 41798486)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.50
, pp. 17969-17974
-
-
Lu, G.1
Westbrooks, J.M.2
Davidson, A.L.3
Chen, J.4
-
27
-
-
0033601321
-
ATP binding properties of the nucleotide-binding folds of SUR1
-
DOI 10.1074/jbc.274.52.37479
-
Matsuo, M., N. Kioka, T. Amachi, and K. Ueda. 1999. ATP binding properties of the nucleotide-binding folds of SUR1. J. Biol. Chem. 274:37479-37482. doi:10.1074/jbc.274.52.37479 (Pubitemid 30016837)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.52
, pp. 37479-37482
-
-
Matsuo, M.1
Kioka, N.2
Amachi, T.3
Ueda, K.4
-
28
-
-
0034666295
-
Different binding properties and affinities for ATP and ADP among sulfonylurea receptor subtypes, SUR1, SUR2A, and SUR2B
-
doi:10.1074/jbc .M004818200
-
Matsuo, M., K. Tanabe, N. Kioka, T. Amachi, and K. Ueda. 2000. Different binding properties and affinities for ATP and ADP among sulfonylurea receptor subtypes, SUR1, SUR2A, and SUR2B. J. Biol. Chem. 275:28757-28763. doi:10.1074/jbc .M004818200
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 28757-28763
-
-
Matsuo, M.1
Tanabe, K.2
Kioka, N.3
Amachi, T.4
Ueda, K.5
-
29
-
-
33750222000
-
In vivo phosphorylation of CFTR promotes formation of a nucleotide-binding domain heterodimer
-
DOI 10.1038/sj.emboj.7601373, PII 7601373
-
Mense, M., P. Vergani, D.M. White, G. Altberg, A.C. Nairn, and D.C. Gadsby. 2006. In vivo phosphorylation of CFTR promotes formation of a nucleotide-binding domain heterodimer. EMBO J. 25:4728-4739. doi: 10.1038/sj.emboj.7601373 (Pubitemid 44607019)
-
(2006)
EMBO Journal
, vol.25
, Issue.20
, pp. 4728-4739
-
-
Mense, M.1
Vergani, P.2
White, D.M.3
Altberg, G.4
Nairn, A.C.5
Gadsby, D.C.6
-
30
-
-
0034625350
-
Nonequivalent nucleotide trapping in the two nucleotide binding folds of the human multidrug resistance protein MRP1
-
DOI 10.1074/jbc.M000792200
-
Nagata, K., M. Nishitani, M. Matsuo, N. Kioka, T. Amachi, and K. Ueda. 2000. Nonequivalent nucleotide trapping in the two nucleotide binding folds of the human multidrug resistance protein MRP1. J. Biol. Chem. 275:17626-17630. doi:10.1074/jbc .M000792200 (Pubitemid 30430809)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.23
, pp. 17626-17630
-
-
Nagata, K.1
Nishitani, M.2
Matsuo, M.3
Kioka, N.4
Amachi, T.5
Ueda, K.6
-
31
-
-
57049124822
-
Structural insights into ABC transporter mechanism
-
doi:10.1016/j.sbi.2008.09.007
-
Oldham, M.L., A.L. Davidson, and J. Chen. 2008. Structural insights into ABC transporter mechanism. Curr. Opin. Struct. Biol. 18:726-733. doi:10.1016/j.sbi.2008.09.007
-
(2008)
Curr. Opin. Struct. Biol.
, vol.18
, pp. 726-733
-
-
Oldham, M.L.1
Davidson, A.L.2
Chen, J.3
-
32
-
-
33645127009
-
The motor domains of ABC-transporters. What can structures tell us?
-
doi:10.1007/s00210-005-0031-4
-
Oswald, C., I.B. Holland, and L. Schmitt. 2006. The motor domains of ABC-transporters. What can structures tell us? Naunyn Schmiedebergs Arch. Pharmacol. 372:385-399. doi:10.1007/s00210-005-0031-4
-
(2006)
Naunyn Schmiedebergs Arch. Pharmacol.
, vol.372
, pp. 385-399
-
-
Oswald, C.1
Holland, I.B.2
Schmitt, L.3
-
33
-
-
33749076230
-
Distinct Structural and Functional Properties of the ATPase Sites in an Asymmetric ABC Transporter
-
DOI 10.1016/j.molcel.2006.07.034, PII S1097276506005363
-
Procko, E., I. Ferrin-O'Connell, S.L. Ng, and R. Gaudet. 2006. Distinct structural and functional properties of the ATPase sites in an asymmetric ABC transporter. Mol. Cell. 24:51-62. doi: 10.1016/ j.molcel.2006.07.034 (Pubitemid 44466678)
-
(2006)
Molecular Cell
, vol.24
, Issue.1
, pp. 51-62
-
-
Procko, E.1
Ferrin-O'Connell, I.2
Ng, S.-L.3
Gaudet, R.4
-
34
-
-
70349333637
-
The mechanism of ABC transporters: General lessons from structural and functional studies of an antigenic peptide transporter
-
doi: 10.1096/ fj.08-121855
-
Procko, E., M.L. O'Mara, W.F. Bennett, D.P. Tieleman, and R. Gaudet. 2009. The mechanism of ABC transporters: general lessons from structural and functional studies of an antigenic peptide transporter. FASEB J. 23:1287-1302. doi: 10.1096/ fj.08-121855
-
(2009)
FASEB J.
, vol.23
, pp. 1287-1302
-
-
Procko, E.1
O'Mara, M.L.2
Bennett, W.F.3
Tieleman, D.P.4
Gaudet, R.5
-
35
-
-
60749083913
-
ABC transporters: The power to change
-
doi:10.1038/ nrm2646
-
Rees, D.C., E.Johnson, and O. Lewinson. 2009. ABC transporters: the power to change. Nat. Rev. Mol. Cell Biol. 10:218-227. doi:10.1038/ nrm2646
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, pp. 218-227
-
-
Rees, D.C.1
Johnson, F.2
Lewinson, O.3
-
36
-
-
0024424270
-
Identification of the cystic fibrosis gene: Cloning and characterization of complementary DNA
-
Riordan, J.R., J.M. Rommens, B. Kerem, N. Alon, R. Rozmahel, Z. Grzelczak, J. Zielenski, S. Lok, N. Plavsic, J.L. Chou, et al. 1989. Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA. Science. 245:1066-1073. doi: 10.1126/science.2475911 (Pubitemid 19231814)
-
(1989)
Science
, vol.245
, Issue.4922
, pp. 1066-1073
-
-
Riordan, J.R.1
Rommens, J.M.2
Kerem, B.-S.3
Alon, N.4
Rozmahel, R.5
Grzelczak, Z.6
Zielinski, J.7
Lok, S.8
Plavsic, N.9
Chou, J.-L.10
Drumm, M.L.11
Iannuzzi, M.C.12
Collins, F.S.13
Tsui, L.-C.14
-
37
-
-
38349136208
-
Genomics and the mechanism of P-glycoprotein (ABCB1)
-
doi: 10.1007/s10863-007-9115-9
-
Sauna, Z.E., I.W. Kim, and S.V. Ambudkar. 2007. Genomics and the mechanism of P-glycoprotein (ABCB1). J. Bioenerg. Biomembr. 39:481-487. doi: 10.1007/s10863-007-9115-9
-
(2007)
J. Bioenerg. Biomembr.
, vol.39
, pp. 481-487
-
-
Sauna, Z.E.1
Kim, I.W.2
Ambudkar, S.V.3
-
38
-
-
33748665424
-
Structural biology: The ins and outs of drug transport
-
DOI 10.1038/443156b, PII 443156B
-
Schuldiner, S. 2006. Structural biology: the ins and outs of drug transport. Nature. 443:156-157. doi:10.1038/443156b (Pubitemid 44387595)
-
(2006)
Nature
, vol.443
, Issue.7108
, pp. 156-157
-
-
Schuldiner, S.1
-
39
-
-
0034460877
-
Vanadate-induced trapping of nucleotides by purified maltose transport complex requires ATP hydrolysis
-
DOI 10.1128/JB.182.23.6570-6576.2000
-
Sharma, S., and A.L. Davidson. 2000. Vanadate-induced trapping of nucleotides by purified maltose transport complex requires ATP hydrolysis. J. Bacteriol. 182:6570-6576. doi: 10.1128/ JB. 182.23.6570-6576.2000 (Pubitemid 32249235)
-
(2000)
Journal of Bacteriology
, vol.182
, Issue.23
, pp. 6570-6576
-
-
Sharma, S.1
Davidson, A.L.2
-
40
-
-
0036342413
-
ATP binding to the motor domain from an ABC transporter drives formation of a nucleotide sandwich dimer
-
doi:10.1016/S1097-2765(02)00576-2
-
Smith, P.C., N. Karpowich, L. Milien, J.E. Moody, J. Rosen, P.J. Thomas, and J.F. Hunt. 2002. ATP binding to the motor domain from an ABC transporter drives formation of a nucleotide sandwich dimer. Mol. Cell. 10:139-149. doi:10.1016/S1097-2765(02)00576-2
-
(2002)
Mol. Cell.
, vol.10
, pp. 139-149
-
-
Smith, P.C.1
Karpowich, N.2
Milien, L.3
Moody, J.E.4
Rosen, J.5
Thomas, P.J.6
Hunt, J.F.7
-
41
-
-
3843140625
-
Combined mutation of catalytic glutamate residues in the two nucleotide binding domains of P-glycoprotein generates a conformation that binds ATP and ADP tightly
-
DOI 10.1074/jbc.M404689200
-
Tombline, G., L.A. Bartholomew, I.L. Urbatsch, and A.E. Senior. 2004. Combined mutation of catalytic glutamate residues in the two nucleotide binding domains of P-glycoprotein generates a conformation that binds ATP and ADP tightly. J. Biol. Chem. 279:31212-31220. doi:10.1074/jbc.M404689200 (Pubitemid 39037786)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.30
, pp. 31212-31220
-
-
Tombline, G.1
Bartholomew, L.A.2
Urbatsch, I.L.3
Senior, A.E.4
-
42
-
-
64549132504
-
State-dependent modulation of CFTR gating by pyrophosphate
-
doi:10.1085/jgp.200810186
-
Tsai, M.F., H. Shimizu, Y. Sohma, M. Li, and T.C. Hwang. 2009. State-dependent modulation of CFTR gating by pyrophosphate. J. Gen. Physiol. 133:405-419. doi:10.1085/jgp.200810186
-
(2009)
J. Gen. Physiol.
, vol.133
, pp. 405-419
-
-
Tsai, M.F.1
Shimizu, H.2
Sohma, Y.3
Li, M.4
Hwang, T.C.5
-
43
-
-
0033574068
-
Cooperative binding of ATP and MgADP in the sulfonylurea receptor is modulated by glibenclamide
-
DOI 10.1073/pnas.96.4.1268
-
Ueda, K., J. Komine, M. Matsuo, S. Seino, and T. Amachi. 1999. Cooperative binding of ATP and MgADP in the sulfonylurea receptor is modulated by glibenclamide. Proc. Natl. Acad. Sci. USA. 96:1268-1272. doi: 10.1073/pnas.96.4.1268 (Pubitemid 29098440)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.4
, pp. 1268-1272
-
-
Ueda, K.1
Komine, J.2
Matsuo, M.3
Seino, S.4
Amachi, T.5
-
44
-
-
0029124166
-
P-glycoprotein is stably inhibited by vanadate-induced trapping of nucleotide at a single catalytic site
-
doi:10.1074/jbc.270.33.19383
-
Urbatsch, I.L., B. Sankaran, J. Weber, and A.E. Senior. 1995. P-glycoprotein is stably inhibited by vanadate-induced trapping of nucleotide at a single catalytic site. J. Biol. Chem. 270:19383-19390. doi:10.1074/jbc.270. 33.19383
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 19383-19390
-
-
Urbatsch, I.L.1
Sankaran, B.2
Weber, J.3
Senior, A.E.4
-
45
-
-
8344241152
-
How do ABC transporters drive transport?
-
DOI 10.1515/BC.2004.121
-
van der Does, C., and R. Tampé. 2004. How do ABC transporters drive transport? Biol. Client. 385:927-933. doi:10.1515/BC.2004.121 (Pubitemid 39481140)
-
(2004)
Biological Chemistry
, vol.385
, Issue.10
, pp. 927-933
-
-
Van Der Does, C.1
Tampe, R.2
-
47
-
-
14544300522
-
CFTR channel opening by ATP-driven tight dimerization of its nucleotide-binding domains
-
DOI 10.1038/nature03313
-
Vergani, P., S.W. Lockless, A.C. Nairn, and D.C. Gadsby. 2005. CFFR channel opening by ATP-driven tight dimerization of its nucleotide-binding domains. Nature. 433:876-880. doi:10.1038/ nature03313 (Pubitemid 40314897)
-
(2005)
Nature
, vol.433
, Issue.7028
, pp. 876-880
-
-
Vergani, P.1
Lockless, S.W.2
Nairn, A.C.3
Gadsby, D.C.4
-
48
-
-
37649004412
-
Flexibility in the ABC transporter MsbA: Alternating access with a twist
-
doi:10.1073/ pnas.0709388104
-
Ward, A., C.L. Reyes, J. Yu, C.B. Roth, and G. Chang. 2007. Flexibility in the ABC transporter MsbA: alternating access with a twist . Proc. Natl. Acad. Sci. USA. 104;19005-19010.doi:10.1073/ pnas.0709388104
-
(2007)
Proc. Natl. Acad. Sci. USA.
, vol.104
, pp. 19005-19010
-
-
Ward, A.1
Reyes, C.L.2
Yu, J.3
Roth, C.B.4
Chang, G.5
-
49
-
-
58149359858
-
Dimer opening of the nucleotide binding domains of ABC transporters after ATP hydrolysis
-
doi:10.1529/biophvsj. 108.139444
-
Wen, P.C., and E. Tajkhorshid. 2008. Dimer opening of the nucleotide binding domains of ABC transporters after ATP hydrolysis. Biophys. J. 95:5100-5110. doi:10.1529/biophvsj. 108.139444
-
(2008)
Biophys. J.
, vol.95
, pp. 5100-5110
-
-
Wen, P.C.1
Tajkhorshid, E.2
-
50
-
-
0035943735
-
The crystal structure of the MJ0796 ATP-binding cassette. Implications for the structural consequences of ATP hydrolysis in the active site of an ABC transporter
-
DOI 10.1074/jbc.M100758200
-
Yuan, Y.R., S. Blecker, O. Martsinkevich, L. Millen, P.J. Thomas, and J.F. Hunt. 2001. The crystal structure of the MJ0796 ATP-binding cassette. Implications for the structural consequences of ATP hydrolysis in the active site of an ABC transporter. J. Biol. Chem. 276:32313-32321. doi:10.1074/jbc. M100758200 (Pubitemid 37384897)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.34
, pp. 32313-32321
-
-
Yuan, Y.-R.1
Blecker, S.2
Martsinkevich, O.3
Millen, L.4
Thomas, P.J.5
Hunt, J.F.6
-
51
-
-
21244454073
-
H662 is the linchpin of ATP hydrolysis in the nucleotide-binding domain of the ABC transporter HlyB
-
DOI 10.1038/sj.emboj.7600657
-
Zaitseva, J., S. Jenewein, T. Jumpertz, I.B. Holland, and L. Schmitt. 2005. H662 is the linchpin of ATP hydrolysis in the nucleotide-binding domain of the ABC transporter HlyB. EMBO J. 24:1901-1910. doi:10.1038/sj.emboj.7600657 (Pubitemid 40896162)
-
(2005)
EMBO Journal
, vol.24
, Issue.11
, pp. 1901-1910
-
-
Zaitseva, J.1
Jenewein, S.2
Jumpertz, T.3
Holland, I.B.4
Schmitt, L.5
-
52
-
-
0032954806
-
Gating of cystic fibrosis transmembrane conductance regulator chloride channels by adenosine triphosphate hydrolysis: Quantitative analysis of a cyclic gating scheme
-
DOI 10.1085/jgp.113.4.541
-
Zeltwanger, S., F. Wang, G.T. Wang, K.D. Gillis, and T.C. Hwang. 1999. Gating of cystic fibrosis transmembrane conductance regulator chloride channels by adenosine triphosphate hydrolysis. Quantitative analysis of a cyclic gating scheme. J. Gen. Physiol. 113:541-554. doi:10.1085/jgp.l13.4.541 (Pubitemid 29169621)
-
(1999)
Journal of General Physiology
, vol.113
, Issue.4
, pp. 541-554
-
-
Zeltwanger, S.1
Wang, F.2
Wang, G.-T.3
Gillis, K.D.4
Hwang, T.-C.5
-
53
-
-
29244490620
-
High affinity ATP/ADP analogues as new tools for studying CFTR gating
-
DOI 10.1113/jphysiol.2005.095083
-
Zhou, Z., X. Wang, M. Li, Y. Sohma, X. Zou, and T.C. Hwang. 2005. High affinity ATP/ADP analogues as new tools for studying CFTR gating. J. Physiol. 569:447-457. doi: 10.1113/jphysiol.2005 .095083 (Pubitemid 41830113)
-
(2005)
Journal of Physiology
, vol.569
, Issue.2
, pp. 447-457
-
-
Zhou, Z.1
Wang, X.2
Li, M.3
Sohma, Y.4
Zou, X.5
Hwang, T.-C.6
-
54
-
-
33749039521
-
The two ATP binding sites of cystic fibrosis transmembrane conductance regulator (CFTR) play distinct roles in gating kinetics and energetics
-
DOI 10.1085/jgp.200609622
-
Zhou, Z., X. Wang, H.Y. Liu, X. Zou, M. Li, and T.C. Hwang. 2006. The two ATP binding sites of cystic fibrosis transmembrane conductance regulator (CFTR) play distinct roles in gating kinetics and energetics. J. Gen. Physiol 128:413-422. doi:10.1085/ jgp.200609622 (Pubitemid 44455100)
-
(2006)
Journal of General Physiology
, vol.128
, Issue.4
, pp. 413-422
-
-
Zhou, Z.1
Wang, X.2
Liu, H.-Y.3
Zou, X.4
Li, M.5
Hwang, T.-C.6
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