-
1
-
-
44949249999
-
Structure, function, and evolution of bacterial ATP-binding cassette systems
-
Davidson, A. L., Dassa, E., Orelle, C.&Chen, J. Structure, function, and evolution of bacterial ATP-binding cassette systems. Microbiol. Mol. Biol. Rev. 72, 317-364 (2008).
-
(2008)
Microbiol. Mol. Biol. Rev.
, vol.72
, pp. 317-364
-
-
Davidson, A.L.1
Dassa, E.2
Orelle, C.3
Chen, J.4
-
2
-
-
84856291637
-
ABC solute importers in bacteria
-
Cui, J.&Davidson, A. L. ABC solute importers in bacteria. Essays Biochem. 50, 85-99 (2011).
-
(2011)
Essays Biochem.
, vol.50
, pp. 85-99
-
-
Cui, J.1
Davidson, A.L.2
-
3
-
-
77953127962
-
A structural classification of substrate-binding proteins
-
Berntsson, R. P. A., Smits, S. H. J., Schmitt, L., Slotboom, D. J.&Poolman, B. A structural classification of substrate-binding proteins. FEBS Lett. 584, 2606-2617 (2010).
-
(2010)
FEBS Lett
, vol.584
, pp. 2606-2617
-
-
Berntsson, R.P.A.1
Smits, S.H.J.2
Schmitt, L.3
Slotboom, D.J.4
Poolman, B.5
-
4
-
-
84947246951
-
The substrate-binding protein in bacterial ABC transporters: Dissecting roles in the evolution of substrate specificity
-
Maqbool, A. et al. The substrate-binding protein in bacterial ABC transporters: dissecting roles in the evolution of substrate specificity. Biochem. Soc. Trans. 43, 1011-1017 (2015).
-
(2015)
Biochem. Soc. Trans.
, vol.43
, pp. 1011-1017
-
-
Maqbool, A.1
-
5
-
-
34548605458
-
Lipid A modification systems in gram-negative bacteria
-
Raetz, C. R. H., Reynolds, C. M., Trent, M. S.&Bishop, R. E. Lipid A modification systems in gram-negative bacteria. Annu. Rev. Biochem. 76, 295-329 (2007).
-
(2007)
Annu. Rev. Biochem.
, vol.76
, pp. 295-329
-
-
Raetz, C.R.H.1
Reynolds, C.M.2
Trent, M.S.3
Bishop, R.E.4
-
6
-
-
77958007497
-
ABC transporters involved in export of cell surface glycoconjugates
-
Cuthbertson, L., Kos, V.&Whitfield, C. ABC transporters involved in export of cell surface glycoconjugates. Microbiol. Mol. Biol. Rev. 74, 341-362 (2010).
-
(2010)
Microbiol. Mol. Biol. Rev.
, vol.74
, pp. 341-362
-
-
Cuthbertson, L.1
Kos, V.2
Whitfield, C.3
-
7
-
-
44449176988
-
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli
-
Ruiz, N., Gronenberg, L. S., Kahne, D.&Silhavy, T. J. Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli. Proc. Natl. Acad. Sci. USA 105, 5537-5542 (2008).
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 5537-5542
-
-
Ruiz, N.1
Gronenberg, L.S.2
Kahne, D.3
Silhavy, T.J.4
-
8
-
-
84890859575
-
Towards understanding promiscuity in multidrug efflux pumps
-
Wong, K., Ma, J., Rothnie, A., Biggin, P. C.&Kerr, I. D. Towards understanding promiscuity in multidrug efflux pumps. Trends Biochem. Sci. 39, 8-16 (2014).
-
(2014)
Trends Biochem. Sci.
, vol.39
, pp. 8-16
-
-
Wong, K.1
Ma, J.2
Rothnie, A.3
Biggin, P.C.4
Kerr, I.D.5
-
9
-
-
64649090980
-
Molecular basis of multidrug transport by ABC transporters
-
Seeger, M. A.&van Veen, H. W. Molecular basis of multidrug transport by ABC transporters. Biochim. Biophys. Acta. 1794, 725-737 (2009).
-
(2009)
Biochim. Biophys. Acta.
, vol.1794
, pp. 725-737
-
-
Seeger, M.A.1
Van Veen, H.W.2
-
10
-
-
84856275069
-
ABC transporters involved in drug resistance in human parasites
-
Leprohon, P., Légaré, D.&Ouellette, M. ABC transporters involved in drug resistance in human parasites. Essays Biochem. 50, 121-144 (2011).
-
(2011)
Essays Biochem.
, vol.50
, pp. 121-144
-
-
Leprohon, P.1
Légaré, D.2
Ouellette, M.3
-
11
-
-
34248222428
-
Plant ATP-binding cassette transporters
-
Rea, P. A. Plant ATP-binding cassette transporters. Annu. Rev. Plant Biol. 58, 347-375 (2007).
-
(2007)
Annu. Rev. Plant Biol.
, vol.58
, pp. 347-375
-
-
Rea, P.A.1
-
12
-
-
0036943710
-
Multifunctionality of plant ABC transporters: More than just detoxifiers
-
Martinoia, E. et al. Multifunctionality of plant ABC transporters: more than just detoxifiers. Planta 214, 345-355 (2002).
-
(2002)
Planta
, vol.214
, pp. 345-355
-
-
Martinoia, E.1
-
13
-
-
78651376221
-
Evolution of ABC transporters by gene duplication and their role in human disease
-
Moitra, K.&Dean, M. Evolution of ABC transporters by gene duplication and their role in human disease. Biol. Chem. 392, 29-37 (2011).
-
(2011)
Biol. Chem.
, vol.392
, pp. 29-37
-
-
Moitra, K.1
Dean, M.2
-
14
-
-
33846658399
-
ABCC8 and ABCC9: ABC transporters that regulate K+ channels
-
Bryan, J. et al. ABCC8 and ABCC9: ABC transporters that regulate K+ channels. Pflugers Arch. 453, 703-718 (2007).
-
(2007)
Pflugers Arch.
, vol.453
, pp. 703-718
-
-
Bryan, J.1
-
15
-
-
61449365340
-
SUR1: A unique ATP-binding cassette protein that functions as an ion channel regulator
-
Aittoniemi, J. et al. SUR1: A unique ATP-binding cassette protein that functions as an ion channel regulator. Phil. Trans. R. Soc. Lond. B 364, 257-267 (2009).
-
(2009)
Phil. Trans. R. Soc. Lond. B
, vol.364
, pp. 257-267
-
-
Aittoniemi, J.1
-
16
-
-
50649123290
-
CFTR function and prospects for therapy
-
Riordan, J. R. CFTR function and prospects for therapy. Annu. Rev. Biochem. 77, 701-726 (2008).
-
(2008)
Annu. Rev. Biochem.
, vol.77
, pp. 701-726
-
-
Riordan, J.R.1
-
17
-
-
84856236848
-
The TAP translocation machinery in adaptive immunity and viral escape mechanisms
-
Abele, R.&Tampé, R. The TAP translocation machinery in adaptive immunity and viral escape mechanisms. Essays Biochem. 50, 249-264 (2011).
-
(2011)
Essays Biochem.
, vol.50
, pp. 249-264
-
-
Abele, R.1
Tampé, R.2
-
18
-
-
84938910744
-
The transporter associated with antigen processing: A key player in adaptive immunity
-
Eggensperger, S.&Tampé, R. The transporter associated with antigen processing: A key player in adaptive immunity. Biol. Chem. 396, 1059-1072 (2015).
-
(2015)
Biol. Chem.
, vol.396
, pp. 1059-1072
-
-
Eggensperger, S.1
Tampé, R.2
-
19
-
-
33749488939
-
Human multidrug resistance ABCB and ABCG transporters: Participation in a chemoimmunity defense system
-
Sarkadi, B., Homolya, L., Szakács, G.&Váradi, A. Human multidrug resistance ABCB and ABCG transporters: participation in a chemoimmunity defense system. Physiol. Rev. 86, 1179-1236 (2006).
-
(2006)
Physiol. Rev.
, vol.86
, pp. 1179-1236
-
-
Sarkadi, B.1
Homolya, L.2
Szakács, G.3
Váradi, A.4
-
20
-
-
0036364467
-
Multidrug resistance in cancer: Role of ATP-dependent transporters
-
Gottesman, M. M., Fojo, T.&Bates, S. E. Multidrug resistance in cancer: role of ATP-dependent transporters. Nat. Rev. Cancer 2, 48-58 (2002).
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 48-58
-
-
Gottesman, M.M.1
Fojo, T.2
Bates, S.E.3
-
21
-
-
84856271899
-
The P-glycoprotein multidrug transporter
-
Sharom, F. J. The P-glycoprotein multidrug transporter. Essays Biochem. 50, 161-178 (2011).
-
(2011)
Essays Biochem.
, vol.50
, pp. 161-178
-
-
Sharom, F.J.1
-
22
-
-
79953799375
-
Advances in the molecular detection of ABC transporters involved in multidrug resistance in cancer
-
Gillet, J. P.&Gottesman, M. M. Advances in the molecular detection of ABC transporters involved in multidrug resistance in cancer. Curr. Pharm. Biotechnol. 12, 686-692 (2011).
-
(2011)
Curr. Pharm. Biotechnol.
, vol.12
, pp. 686-692
-
-
Gillet, J.P.1
Gottesman, M.M.2
-
23
-
-
84455171488
-
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans
-
Dawson, S., Stahl, S., Paul, N., Barber, J.&Kenna, J. G. In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans. Drug Metab. Dispos. 40, 130-138 (2012).
-
(2012)
Drug Metab. Dispos.
, vol.40
, pp. 130-138
-
-
Dawson, S.1
Stahl, S.2
Paul, N.3
Barber, J.4
Kenna, J.G.5
-
24
-
-
84935882341
-
Molecular mechanisms for biliary phospholipid and drug efflux mediated by ABCB4 and bile salts
-
Morita, S. Y.&Terada, T. Molecular mechanisms for biliary phospholipid and drug efflux mediated by ABCB4 and bile salts. BioMed Res. Int. 2014, 954781 (2014).
-
(2014)
BioMed Res. Int.
, vol.2014
, pp. 954781
-
-
Morita, S.Y.1
Terada, T.2
-
25
-
-
82755163760
-
Canalicular ABC transporters and liver disease
-
Nicolaou, M. et al. Canalicular ABC transporters and liver disease. J. Pathol. 226, 300-315 (2012).
-
(2012)
J. Pathol.
, vol.226
, pp. 300-315
-
-
Nicolaou, M.1
-
26
-
-
84947220788
-
Lipid flopping in the liver
-
Linton, K. J. Lipid flopping in the liver. Biochem. Soc. Trans. 43, 1003-1010 (2015).
-
(2015)
Biochem. Soc. Trans.
, vol.43
, pp. 1003-1010
-
-
Linton, K.J.1
-
27
-
-
77954374158
-
Role of the bile salt export pump, BSEP, in acquired forms of cholestasis
-
Stieger, B. Role of the bile salt export pump, BSEP, in acquired forms of cholestasis. Drug Metab. Rev. 42, 437-445 (2010).
-
(2010)
Drug Metab. Rev.
, vol.42
, pp. 437-445
-
-
Stieger, B.1
-
28
-
-
84856282091
-
The controversial role of ABC transporters in clinical oncology
-
Tamaki, A., Ierano, C., Szakacs, G., Robey, R. W.&Bates, S. E. The controversial role of ABC transporters in clinical oncology. Essays Biochem. 50, 209-232 (2011).
-
(2011)
Essays Biochem.
, vol.50
, pp. 209-232
-
-
Tamaki, A.1
Ierano, C.2
Szakacs, G.3
Robey, R.W.4
Bates, S.E.5
-
29
-
-
84887898959
-
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development
-
Morgan, R. E. et al. A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicol. Sci. 136, 216-241 (2013).
-
(2013)
Toxicol. Sci.
, vol.136
, pp. 216-241
-
-
Morgan, R.E.1
-
30
-
-
84896373130
-
Overview of experimental models of the blood-brain barrier in CNS drug discovery
-
Palmer, A. M.&Alavijeh, M. S. Overview of experimental models of the blood-brain barrier in CNS drug discovery. Curr Protoc Pharmacol. 62, 7. 15 (2013).
-
(2013)
Curr Protoc Pharmacol.
, vol.62
, pp. 715
-
-
Palmer, A.M.1
Alavijeh, M.S.2
-
31
-
-
84937628052
-
Prediction of drug-ABC-transporter interaction: Recent advances and future challenges
-
Montanari, F.&Ecker, G. F. Prediction of drug-ABC-transporter interaction: recent advances and future challenges. Adv. Drug Deliv. Rev. 86, 17-26 (2015).
-
(2015)
Adv. Drug Deliv. Rev.
, vol.86
, pp. 17-26
-
-
Montanari, F.1
Ecker, G.F.2
-
32
-
-
47249110343
-
Structural basis of trans-inhibition in a molybdate/tungstate ABC transporter
-
Gerber, S., Comellas-Bigler, M., Goetz, B. A.&Locher, K. P. Structural basis of trans-inhibition in a molybdate/tungstate ABC transporter. Science 321, 246-250 (2008).
-
(2008)
Science
, vol.321
, pp. 246-250
-
-
Gerber, S.1
Comellas-Bigler, M.2
Goetz, B.A.3
Locher, K.P.4
-
33
-
-
47249084799
-
The high-affinity E. Coli methionine ABC transporter: Structure and allosteric regulation
-
Kadaba, N. S., Kaiser, J. T., Johnson, E., Lee, A.&Rees, D. C. The high-affinity E. coli methionine ABC transporter: structure and allosteric regulation. Science 321, 250-253 (2008).
-
(2008)
Science
, vol.321
, pp. 250-253
-
-
Kadaba, N.S.1
Kaiser, J.T.2
Johnson, E.3
Lee, A.4
Rees, D.C.5
-
34
-
-
84882338908
-
Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain
-
Ward, A. B. et al. Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain. Proc. Natl. Acad. Sci. USA 110, 13386-13391 (2013).
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 13386-13391
-
-
Ward, A.B.1
-
35
-
-
34447311648
-
Uptake or extrusion: Crystal structures of full ABC transporters suggest a common mechanism
-
Dawson, R. J. P., Hollenstein, K.&Locher, K. P. Uptake or extrusion: crystal structures of full ABC transporters suggest a common mechanism. Mol. Microbiol. 65, 250-257 (2007).
-
(2007)
Mol. Microbiol.
, vol.65
, pp. 250-257
-
-
Dawson, R.J.P.1
Hollenstein, K.2
Locher, K.P.3
-
36
-
-
57049124822
-
Structural insights into ABC transporter mechanism
-
Oldham, M. L., Davidson, A. L.&Chen, J. Structural insights into ABC transporter mechanism. Curr. Opin. Struct. Biol. 18, 726-733 (2008).
-
(2008)
Curr. Opin. Struct. Biol.
, vol.18
, pp. 726-733
-
-
Oldham, M.L.1
Davidson, A.L.2
Chen, J.3
-
37
-
-
75149135645
-
Multidrug efflux pumps: The structures of prokaryotic ATP-binding cassette transporter efflux pumps and implications for our understanding of eukaryotic P-glycoproteins and homologues
-
Kerr, I. D., Jones, P. M.&George, A. M. Multidrug efflux pumps: The structures of prokaryotic ATP-binding cassette transporter efflux pumps and implications for our understanding of eukaryotic P-glycoproteins and homologues. FEBS J. 277, 550-563 (2010).
-
(2010)
FEBS J.
, vol.277
, pp. 550-563
-
-
Kerr, I.D.1
Jones, P.M.2
George, A.M.3
-
38
-
-
84864564117
-
Perspectives on the structure-function of ABC transporters: The Switch and Constant Contact models
-
George, A. M.&Jones, P. M. Perspectives on the structure-function of ABC transporters: The Switch and Constant Contact models. Prog. Biophys. Mol. Biol. 109, 95-107 (2012).
-
(2012)
Prog. Biophys. Mol. Biol.
, vol.109
, pp. 95-107
-
-
George, A.M.1
Jones, P.M.2
-
39
-
-
0035852667
-
Trapping the transition state of an ATP-binding cassette transporter: Evidence for a concerted mechanism of maltose transport
-
Chen, J., Sharma, S., Quiocho, F. A.&Davidson, A. L. Trapping the transition state of an ATP-binding cassette transporter: evidence for a concerted mechanism of maltose transport. Proc. Natl. Acad. Sci. USA 98, 1525-1530 (2001).
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 1525-1530
-
-
Chen, J.1
Sharma, S.2
Quiocho, F.A.3
Davidson, A.L.4
-
40
-
-
84947029309
-
Structure of a bacterial ABC transporter involved in the import of an acidic polysaccharide alginate
-
Maruyama, Y. et al. Structure of a bacterial ABC transporter involved in the import of an acidic polysaccharide alginate. Structure 23, 1643-1654 (2015).
-
(2015)
Structure
, vol.23
, pp. 1643-1654
-
-
Maruyama, Y.1
-
41
-
-
33947154878
-
Structure of an ABC transporter in complex with its binding protein
-
Hollenstein, K., Frei, D. C.&Locher, K. P. Structure of an ABC transporter in complex with its binding protein. Nature 446, 213-216 (2007).
-
(2007)
Nature
, vol.446
, pp. 213-216
-
-
Hollenstein, K.1
Frei, D.C.2
Locher, K.P.3
-
42
-
-
36549018568
-
Crystal structure of a catalytic intermediate of the maltose transporter
-
Oldham, M. L., Khare, D., Quiocho, F. A., Davidson, A. L.&Chen, J. Crystal structure of a catalytic intermediate of the maltose transporter. Nature 450, 515-521 (2007).
-
(2007)
Nature
, vol.450
, pp. 515-521
-
-
Oldham, M.L.1
Khare, D.2
Quiocho, F.A.3
Davidson, A.L.4
Chen, J.5
-
43
-
-
0041529863
-
The ATP/substrate stoichiometry of the ATP-binding cassette (ABC) transporter OpuA
-
Patzlaff, J. S., van der Heide, T.&Poolman, B. The ATP/substrate stoichiometry of the ATP-binding cassette (ABC) transporter OpuA. J. Biol. Chem. 278, 29546-29551 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 29546-29551
-
-
Patzlaff, J.S.1
Van Der Heide, T.2
Poolman, B.3
-
44
-
-
84926432107
-
The allosteric regulatory mechanism of the Escherichia coli MetNI methionine ATP binding cassette (ABC) transporter
-
Yang, J. G.&Rees, D. C. The allosteric regulatory mechanism of the Escherichia coli MetNI methionine ATP binding cassette (ABC) transporter. J. Biol. Chem. 290, 9135-9140 (2015).
-
(2015)
J. Biol. Chem.
, vol.290
, pp. 9135-9140
-
-
Yang, J.G.1
Rees, D.C.2
-
45
-
-
84880511070
-
Carbon catabolite repression of the maltose transporter revealed by X-ray crystallography
-
Chen, S., Oldham, M. L., Davidson, A. L.&Chen, J. Carbon catabolite repression of the maltose transporter revealed by X-ray crystallography. Nature 499, 364-368 (2013).
-
(2013)
Nature
, vol.499
, pp. 364-368
-
-
Chen, S.1
Oldham, M.L.2
Davidson, A.L.3
Chen, J.4
-
46
-
-
79953302147
-
Recent insights into iron import by bacteria
-
Braun, V.&Hantke, K. Recent insights into iron import by bacteria. Curr. Opin. Chem. Biol. 15, 328-334 (2011).
-
(2011)
Curr. Opin. Chem. Biol.
, vol.15
, pp. 328-334
-
-
Braun, V.1
Hantke, K.2
-
47
-
-
0343395846
-
ABC transporter-mediated uptake of iron, siderophores, heme and vitamin B12
-
Köster, W. ABC transporter-mediated uptake of iron, siderophores, heme and vitamin B12. Res. Microbiol. 152, 291-301 (2001).
-
(2001)
Res. Microbiol.
, vol.152
, pp. 291-301
-
-
Köster, W.1
-
48
-
-
84867670628
-
Structure of AMP-PNP-bound vitamin B12 transporter BtuCD-F
-
Korkhov, V. M., Mireku, S. A.&Locher, K. P. Structure of AMP-PNP-bound vitamin B12 transporter BtuCD-F. Nature 490, 367-372 (2012).
-
(2012)
Nature
, vol.490
, pp. 367-372
-
-
Korkhov, V.M.1
Mireku, S.A.2
Locher, K.P.3
-
49
-
-
84923799962
-
Structure of AMP-PNP-bound BtuCD and mechanism of ATP-powered vitamin B12 transport by BtuCD-F
-
Korkhov, V. M., Mireku, S. A., Veprintsev, D. B.&Locher, K. P. Structure of AMP-PNP-bound BtuCD and mechanism of ATP-powered vitamin B12 transport by BtuCD-F. Nat. Struct. Mol. Biol. 21, 1097-1099 (2014).
-
(2014)
Nat. Struct. Mol. Biol.
, vol.21
, pp. 1097-1099
-
-
Korkhov, V.M.1
Mireku, S.A.2
Veprintsev, D.B.3
Locher, K.P.4
-
50
-
-
58149512047
-
Distinct gate conformations of the ABC transporter BtuCD revealed by electron spin resonance spectroscopy and chemical cross-linking
-
Goetz, B. A., Perozo, E.&Locher, K. P. Distinct gate conformations of the ABC transporter BtuCD revealed by electron spin resonance spectroscopy and chemical cross-linking. FEBS Lett. 583, 266-270 (2009).
-
(2009)
FEBS Lett.
, vol.583
, pp. 266-270
-
-
Goetz, B.A.1
Perozo, E.2
Locher, K.P.3
-
51
-
-
34548671159
-
Asymmetry in the structure of the ABC transporter-binding protein complex BtuCD-BtuF
-
Hvorup, R. N. et al. Asymmetry in the structure of the ABC transporter-binding protein complex BtuCD-BtuF. Science 317, 1387-1390 (2007).
-
(2007)
Science
, vol.317
, pp. 1387-1390
-
-
Hvorup, R.N.1
-
52
-
-
81755171418
-
Transmembrane gate movements in the type II ATP-binding cassette (ABC) importer BtuCD-F during nucleotide cycle
-
Joseph, B., Jeschke, G., Goetz, B. A., Locher, K. P.&Bordignon, E. Transmembrane gate movements in the type II ATP-binding cassette (ABC) importer BtuCD-F during nucleotide cycle. J. Biol. Chem. 286, 41008-41017 (2011).
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 41008-41017
-
-
Joseph, B.1
Jeschke, G.2
Goetz, B.A.3
Locher, K.P.4
Bordignon, E.5
-
53
-
-
0037052565
-
The E. Coli BtuCD structure: A framework for ABC transporter architecture and mechanism
-
Locher, K. P., Lee, A. T.&Rees, D. C. The E. coli BtuCD structure: A framework for ABC transporter architecture and mechanism. Science 296, 1091-1098 (2002).
-
(2002)
Science
, vol.296
, pp. 1091-1098
-
-
Locher, K.P.1
Lee, A.T.2
Rees, D.C.3
-
54
-
-
33748644877
-
Structure of a bacterial multidrug ABC transporter
-
Dawson, R. J. P.&Locher, K. P. Structure of a bacterial multidrug ABC transporter. Nature 443, 180-185 (2006).
-
(2006)
Nature
, vol.443
, pp. 180-185
-
-
Dawson, R.J.P.1
Locher, K.P.2
-
55
-
-
84861310612
-
Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation
-
Hohl, M., Briand, C., Grütter, M. G.&Seeger, M. A. Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation. Nat. Struct. Mol. Biol. 19, 395-402 (2012).
-
(2012)
Nat. Struct. Mol. Biol.
, vol.19
, pp. 395-402
-
-
Hohl, M.1
Briand, C.2
Grütter, M.G.3
Seeger, M.A.4
-
56
-
-
84905040016
-
Structural basis for allosteric cross-talk between the asymmetric nucleotide binding sites of a heterodimeric ABC exporter
-
Hohl, M. et al. Structural basis for allosteric cross-talk between the asymmetric nucleotide binding sites of a heterodimeric ABC exporter. Proc. Natl. Acad. Sci. USA 111, 11025-11030 (2014).
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. 11025-11030
-
-
Hohl, M.1
-
57
-
-
84937844507
-
Crystal structures of a polypeptide processing and secretion transporter
-
Lin, D. Y. W., Huang, S.&Chen, J. Crystal structures of a polypeptide processing and secretion transporter. Nature 523, 425-430 (2015).
-
(2015)
Nature
, vol.523
, pp. 425-430
-
-
Lin, D.Y.W.1
Huang, S.2
Chen, J.3
-
58
-
-
84879002569
-
Structures of ABCB10, a human ATP-binding cassette transporter in apo-and nucleotide-bound states
-
Shintre, C. A. et al. Structures of ABCB10, a human ATP-binding cassette transporter in apo-and nucleotide-bound states. Proc. Natl. Acad. Sci. USA 110, 9710-9715 (2013).
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 9710-9715
-
-
Shintre, C.A.1
-
59
-
-
47049101437
-
Mutational analysis of ABC proteins
-
Loo, T. W.&Clarke, D. M. Mutational analysis of ABC proteins. Arch. Biochem. Biophys. 476, 51-64 (2008).
-
(2008)
Arch. Biochem. Biophys.
, vol.476
, pp. 51-64
-
-
Loo, T.W.1
Clarke, D.M.2
-
60
-
-
84891912095
-
Multiple transport-active binding sites are available for a single substrate on human P-glycoprotein (ABCB1)
-
Chufan, E. E. et al. Multiple transport-active binding sites are available for a single substrate on human P-glycoprotein (ABCB1). PLoS One 8, e82463 (2013).
-
(2013)
PLoS One
, vol.8
, pp. e82463
-
-
Chufan, E.E.1
-
61
-
-
84937605067
-
Multiple drug transport pathways through human P-glycoprotein
-
McCormick, J. W., Vogel, P. D.&Wise, J. G. Multiple drug transport pathways through human P-glycoprotein. Biochemistry 54, 4374-4390 (2015).
-
(2015)
Biochemistry
, vol.54
, pp. 4374-4390
-
-
McCormick, J.W.1
Vogel, P.D.2
Wise, J.G.3
-
62
-
-
79952167215
-
Conformation of peptides bound to the transporter associated with antigen processing (TAP)
-
Herget, M. et al. Conformation of peptides bound to the transporter associated with antigen processing (TAP). Proc. Natl. Acad. Sci. USA 108, 1349-1354 (2011).
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 1349-1354
-
-
Herget, M.1
-
63
-
-
84903478669
-
Structure of an antibacterial peptide ATP-binding cassette transporter in a novel outward occluded state
-
Choudhury, H. G. et al. Structure of an antibacterial peptide ATP-binding cassette transporter in a novel outward occluded state. Proc. Natl. Acad. Sci. USA 111, 9145-9150 (2014).
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. 9145-9150
-
-
Choudhury, H.G.1
-
64
-
-
33847134349
-
Structure of the multidrug ABC transporter Sav1866 from Staphylococcus aureus in complex with AMP-PNP
-
Dawson, R. J. P.&Locher, K. P. Structure of the multidrug ABC transporter Sav1866 from Staphylococcus aureus in complex with AMP-PNP. FEBS Lett. 581, 935-938 (2007).
-
(2007)
FEBS Lett.
, vol.581
, pp. 935-938
-
-
Dawson, R.J.P.1
Locher, K.P.2
-
65
-
-
0032492724
-
Human P-glycoprotein exhibits reduced affinity for substrates during a catalytic transition state
-
Ramachandra, M. et al. Human P-glycoprotein exhibits reduced affinity for substrates during a catalytic transition state. Biochemistry 37, 5010-5019 (1998).
-
(1998)
Biochemistry
, vol.37
, pp. 5010-5019
-
-
Ramachandra, M.1
-
66
-
-
84940550346
-
Structure and mechanism of an active lipid-linked oligosaccharide flippase
-
Perez, C. et al. Structure and mechanism of an active lipid-linked oligosaccharide flippase. Nature 524, 433-438 (2015).
-
(2015)
Nature
, vol.524
, pp. 433-438
-
-
Perez, C.1
-
67
-
-
84922645558
-
Subnanometre-resolution electron cryomicroscopy structure of a heterodimeric ABC exporter
-
Kim, J. et al. Subnanometre-resolution electron cryomicroscopy structure of a heterodimeric ABC exporter. Nature 517, 396-400 (2015).
-
(2015)
Nature
, vol.517
, pp. 396-400
-
-
Kim, J.1
-
68
-
-
84956641350
-
A mechanism of viral immune evasion revealed by cryo-EM analysis of the TAP transporter
-
Oldham, M. L. et al. A mechanism of viral immune evasion revealed by cryo-EM analysis of the TAP transporter. Nature 529, 537-540 (2016).
-
(2016)
Nature
, vol.529
, pp. 537-540
-
-
Oldham, M.L.1
-
69
-
-
84900860340
-
Conformational dynamics of the nucleotide binding domains and the power stroke of a heterodimeric ABC transporter
-
Mishra, S. et al. Conformational dynamics of the nucleotide binding domains and the power stroke of a heterodimeric ABC transporter. eLife 3, e02740 (2014).
-
(2014)
ELife
, vol.3
, pp. e02740
-
-
Mishra, S.1
-
70
-
-
79953183043
-
Asymmetric ATP hydrolysis cycle of the heterodimeric multidrug ABC transport complex TmrAB from Thermus thermophilus
-
Zutz, A. et al. Asymmetric ATP hydrolysis cycle of the heterodimeric multidrug ABC transport complex TmrAB from Thermus thermophilus. J. Biol. Chem. 286, 7104-7115 (2011).
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 7104-7115
-
-
Zutz, A.1
-
71
-
-
84862012971
-
Asymmetry in the homodimeric ABC transporter MsbA recognized by a DARPin
-
Mittal, A., Böhm, S., Grütter, M. G., Bordignon, E.&Seeger, M. A. Asymmetry in the homodimeric ABC transporter MsbA recognized by a DARPin. J. Biol. Chem. 287, 20395-20406 (2012).
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 20395-20406
-
-
Mittal, A.1
Böhm, S.2
Grütter, M.G.3
Bordignon, E.4
Seeger, M.A.5
-
72
-
-
33746537716
-
A structural analysis of asymmetry required for catalytic activity of an ABC-ATPase domain dimer
-
Zaitseva, J. et al. A structural analysis of asymmetry required for catalytic activity of an ABC-ATPase domain dimer. EMBO J. 25, 3432-3443 (2006).
-
(2006)
EMBO J
, vol.25
, pp. 3432-3443
-
-
Zaitseva, J.1
-
73
-
-
61449361477
-
ATP hydrolysis-driven gating in cystic fibrosis transmembrane conductance regulator
-
Muallem, D.&Vergani, P. ATP hydrolysis-driven gating in cystic fibrosis transmembrane conductance regulator. Phil. Trans. R. Soc. Lond. B 364, 247-255 (2009).
-
(2009)
Phil. Trans. R. Soc. Lond. B
, vol.364
, pp. 247-255
-
-
Muallem, D.1
Vergani, P.2
-
74
-
-
84921028041
-
Mechanistic determinants of the directionality and energetics of active export by a heterodimeric ABC transporter
-
Grossmann, N. et al. Mechanistic determinants of the directionality and energetics of active export by a heterodimeric ABC transporter. Nat. Commun. 5, 5419 (2014).
-
(2014)
Nat. Commun.
, vol.5
, pp. 5419
-
-
Grossmann, N.1
-
75
-
-
84915827775
-
A reciprocating twin-channel model for ABC transporters
-
Jones, P. M.&George, A. M. A reciprocating twin-channel model for ABC transporters. Q. Rev. Biophys. 47, 189-220 (2014).
-
(2014)
Q. Rev. Biophys.
, vol.47
, pp. 189-220
-
-
Jones, P.M.1
George, A.M.2
-
76
-
-
70349646681
-
Membrane porters of ATP-binding cassette transport systems are polyphyletic
-
Wang, B., Dukarevich, M., Sun, E. I., Yen, M. R.&Saier, M. H. Jr. Membrane porters of ATP-binding cassette transport systems are polyphyletic. J. Membr. Biol. 231, 1-10 (2009).
-
(2009)
J. Membr. Biol.
, vol.231
, pp. 1-10
-
-
Wang, B.1
Dukarevich, M.2
Sun, E.I.3
Yen, M.R.4
Saier, M.H.5
-
77
-
-
84877038330
-
Evolutionary relationships of ATP-binding cassette (ABC) uptake porters
-
Zheng, W. H. et al. Evolutionary relationships of ATP-binding cassette (ABC) uptake porters. BMC Microbiol. 13, 98 (2013).
-
(2013)
BMC Microbiol.
, vol.13
, pp. 98
-
-
Zheng, W.H.1
-
78
-
-
84947205644
-
Watching conformational dynamics of ABC transporters with single-molecule tools
-
Husada, F. et al. Watching conformational dynamics of ABC transporters with single-molecule tools. Biochem. Soc. Trans. 43, 1041-1047 (2015).
-
(2015)
Biochem. Soc. Trans.
, vol.43
, pp. 1041-1047
-
-
Husada, F.1
-
79
-
-
84899982879
-
The central cavity of ABCB1 undergoes alternating access during ATP hydrolysis
-
van Wonderen, J. H. et al. The central cavity of ABCB1 undergoes alternating access during ATP hydrolysis. FEBS J. 281, 2190-2201 (2014).
-
(2014)
FEBS J.
, vol.281
, pp. 2190-2201
-
-
Van Wonderen, J.H.1
-
80
-
-
84947223826
-
Investigating the dynamic nature of the ABC transporters: ABCB1 and MsbA as examples for the potential synergies of MD theory and EPR applications
-
Stockner, T., Mullen, A.&MacMillan, F. Investigating the dynamic nature of the ABC transporters: ABCB1 and MsbA as examples for the potential synergies of MD theory and EPR applications. Biochem. Soc. Trans. 43, 1023-1032 (2015).
-
(2015)
Biochem. Soc. Trans.
, vol.43
, pp. 1023-1032
-
-
Stockner, T.1
Mullen, A.2
MacMillan, F.3
-
81
-
-
84942598594
-
Conformational changes of the antibacterial peptide ATP binding cassette transporter McjD revealed by molecular dynamics simulations
-
Gu, R. X. et al. Conformational changes of the antibacterial peptide ATP binding cassette transporter McjD revealed by molecular dynamics simulations. Biochemistry 54, 5989-5998 (2015).
-
(2015)
Biochemistry
, vol.54
, pp. 5989-5998
-
-
Gu, R.X.1
-
82
-
-
84888089116
-
Mechanistic picture for conformational transition of a membrane transporter at atomic resolution
-
Moradi, M.&Tajkhorshid, E. Mechanistic picture for conformational transition of a membrane transporter at atomic resolution. Proc. Natl. Acad. Sci. USA 110, 18916-18921 (2013).
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 18916-18921
-
-
Moradi, M.1
Tajkhorshid, E.2
-
83
-
-
84885019160
-
Structure, biosynthesis, and function of bacterial capsular polysaccharides synthesized by ABC transporter-dependent pathways
-
Willis, L. M.&Whitfield, C. Structure, biosynthesis, and function of bacterial capsular polysaccharides synthesized by ABC transporter-dependent pathways. Carbohydr. Res. 378, 35-44 (2013).
-
(2013)
Carbohydr. Res.
, vol.378
, pp. 35-44
-
-
Willis, L.M.1
Whitfield, C.2
-
84
-
-
18844428872
-
Type 1 protein secretion in bacteria, the ABC-transporter dependent pathway
-
Holland, I. B., Schmitt, L.&Young, J. Type 1 protein secretion in bacteria, the ABC-transporter dependent pathway. Mol. Membr. Biol. 22, 29-39 (2005).
-
(2005)
Mol. Membr. Biol.
, vol.22
, pp. 29-39
-
-
Holland, I.B.1
Schmitt, L.2
Young, J.3
-
85
-
-
84897000286
-
The resolution revolution
-
Kühlbrandt, W. The resolution revolution. Science 343, 1443-1444 (2014).
-
(2014)
Science
, vol.343
, pp. 1443-1444
-
-
Kühlbrandt, W.1
-
86
-
-
60749083913
-
ABC transporters: The power to change
-
Rees, D. C., Johnson, E.&Lewinson, O. ABC transporters: The power to change. Nat. Rev. Mol. Cell Biol. 10, 218-227 (2009).
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, pp. 218-227
-
-
Rees, D.C.1
Johnson, E.2
Lewinson, O.3
-
87
-
-
84877756304
-
Crystal structure of a folate energy-coupling factor transporter from Lactobacillus brevis
-
Xu, K. et al. Crystal structure of a folate energy-coupling factor transporter from Lactobacillus brevis. Nature 497, 268-271 (2013).
-
(2013)
Nature
, vol.497
, pp. 268-271
-
-
Xu, K.1
-
88
-
-
70349333637
-
The mechanism of ABC transporters: General lessons from structural and functional studies of an antigenic peptide transporter
-
Procko, E., O'Mara, M. L., Bennett, W. F. D., Tieleman, D. P.&Gaudet, R. The mechanism of ABC transporters: general lessons from structural and functional studies of an antigenic peptide transporter. FASEB J. 23, 1287-1302 (2009).
-
(2009)
FASEB J.
, vol.23
, pp. 1287-1302
-
-
Procko, E.1
O'Mara, M.L.2
Bennett, W.F.D.3
Tieleman, D.P.4
Gaudet, R.5
-
89
-
-
84922342044
-
Structure and mechanism of ABC transporters
-
Wilkens, S. Structure and mechanism of ABC transporters. F1000Prime Rep. 7, 14 (2015).
-
(2015)
F1000Prime Rep.
, vol.7
, pp. 14
-
-
Wilkens, S.1
-
90
-
-
84897055167
-
Structural diversity of ABC transporters
-
ter Beek, J., Guskov, A.&Slotboom, D. J. Structural diversity of ABC transporters. J. Gen. Physiol. 143, 419-435 (2014).
-
(2014)
J. Gen. Physiol.
, vol.143
, pp. 419-435
-
-
Ter Beek, J.1
Guskov, A.2
Slotboom, D.J.3
-
91
-
-
84888874764
-
Structure and mechanism of energy-coupling factor transporters
-
Zhang, P. Structure and mechanism of energy-coupling factor transporters. Trends Microbiol. 21, 652-659 (2013).
-
(2013)
Trends Microbiol.
, vol.21
, pp. 652-659
-
-
Zhang, P.1
-
92
-
-
84867883248
-
Crystal structure of the multidrug transporter P-glycoprotein from
-
Jin, M. S., Oldham, M. L., Zhang, Q. J.&Chen, J. Crystal structure of the multidrug transporter P-glycoprotein from. Caenorhabditis elegans. Nature 490, 566-569 (2012).
-
(2012)
Caenorhabditis Elegans. Nature
, vol.490
, pp. 566-569
-
-
Jin, M.S.1
Oldham, M.L.2
Zhang, Q.J.3
Chen, J.4
-
93
-
-
84896512558
-
Structural basis for gating mechanisms of a eukaryotic P-glycoprotein homolog
-
Kodan, A. et al. Structural basis for gating mechanisms of a eukaryotic P-glycoprotein homolog. Proc. Natl. Acad. Sci. USA 111, 4049-4054 (2014).
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. 4049-4054
-
-
Kodan, A.1
-
94
-
-
84896803955
-
Structural basis for heavy metal detoxification by an Atm1-type ABC exporter
-
Lee, J. Y., Yang, J. G., Zhitnitsky, D., Lewinson, O.&Rees, D. C. Structural basis for heavy metal detoxification by an Atm1-type ABC exporter. Science 343, 1133-1136 (2014).
-
(2014)
Science
, vol.343
, pp. 1133-1136
-
-
Lee, J.Y.1
Yang, J.G.2
Zhitnitsky, D.3
Lewinson, O.4
Rees, D.C.5
-
95
-
-
84900449189
-
Refined structures of mouse P-glycoprotein
-
Li, J., Jaimes, K. F.&Aller, S. G. Refined structures of mouse P-glycoprotein. Protein Sci. 23, 34-46 (2014).
-
(2014)
Protein Sci.
, vol.23
, pp. 34-46
-
-
Li, J.1
Jaimes, K.F.2
Aller, S.G.3
-
96
-
-
84896800834
-
Crystal structures of nucleotide-free and glutathione-bound mitochondrial ABC transporter Atm1
-
Srinivasan, V., Pierik, A. J.&Lill, R. Crystal structures of nucleotide-free and glutathione-bound mitochondrial ABC transporter Atm1. Science 343, 1137-1140 (2014).
-
(2014)
Science
, vol.343
, pp. 1137-1140
-
-
Srinivasan, V.1
Pierik, A.J.2
Lill, R.3
-
97
-
-
37649004412
-
Flexibility in the ABC transporter MsbA: Alternating access with a twist
-
Ward, A., Reyes, C. L., Yu, J., Roth, C. B.&Chang, G. Flexibility in the ABC transporter MsbA: Alternating access with a twist. Proc. Natl. Acad. Sci. USA 104, 19005-19010 (2007).
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 19005-19010
-
-
Ward, A.1
Reyes, C.L.2
Yu, J.3
Roth, C.B.4
Chang, G.5
-
98
-
-
61449341855
-
Structure and mechanism of ATP-binding cassette transporters
-
Locher, K. P. Structure and mechanism of ATP-binding cassette transporters. Phil. Trans. R. Soc. Lond. B 364, 239-245 (2009).
-
(2009)
Phil. Trans. R. Soc. Lond. B
, vol.364
, pp. 239-245
-
-
Locher, K.P.1
-
99
-
-
38449119773
-
Conformational motion of the ABC transporter MsbA induced by ATP hydrolysis
-
Borbat, P. P. et al. Conformational motion of the ABC transporter MsbA induced by ATP hydrolysis. PLoS Biol. 5, e271 (2007).
-
(2007)
PLoS Biol.
, vol.5
, pp. e271
-
-
Borbat, P.P.1
-
100
-
-
77951877993
-
Human P-glycoprotein is active when the two halves are clamped together in the closed conformation
-
Loo, T. W., Bartlett, M. C.&Clarke, D. M. Human P-glycoprotein is active when the two halves are clamped together in the closed conformation. Biochem. Biophys. Res. Commun. 395, 436-440 (2010).
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.395
, pp. 436-440
-
-
Loo, T.W.1
Bartlett, M.C.2
Clarke, D.M.3
|