Development of allergen-specific T-cell memory in atopic and normal children

Lancet

Volumn 353, Issue 9148, 1999, Pages 196-200

  Prescott, Susan L ^a   Macaubas, Claudia ^a   Smallacombe, Troy ^a   Holt, Barbara J ^a   Sly, Peter D ^a   Holt, Patrick G ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; BETA ACTIN; CYTOKINE; GAMMA INTERFERON; HOUSE DUST ALLERGEN; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 6; MESSENGER RNA; TETANUS TOXOID;

ARTICLE; ATOPY; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME LINKED IMMUNOSORBENT ASSAY; HELPER CELL; HUMAN; HUMAN CELL; IMMUNOLOGICAL MEMORY; INFANT; MONONUCLEAR CELL; POSTNATAL DEVELOPMENT; PRESCHOOL CHILD; PRIORITY JOURNAL; RESPIRATORY TRACT DISEASE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE;

EID: 0033573788     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(98)05104-6     Document Type: Article

References (23)

1. Peat JK, van den Berg RH, Green WF, Mellis CM, Leeder SR, Woolcock AJ Changing prevalence of asthma in Australian children. BMJ. 308:1994;1591-1596.
2. Holt PG A potential vaccine strategy for asthma and allied atopic diseases during early childhood. Lancet. 344:1994;456-458.
3. Holt PG, Sly PD Allergic respiratory disease: strategic targets for primary prevention during childhood. Thorax. 52:1997;1-4.
4. Woolcock AJ, Peat JK, Trevillion LM Is the increase in asthma prevalence linked to increase in allergen load? Allergy. 50:1995;935-940.
5. + T lymphocytes in atopic patients. J Immunol. 144:1990;4651-4656.
6. Romagnani S Induction of Th1 and Th2 responses: a key role for the "natural" immune response? Immunol Today. 13:1992;379-381.
7. Yabuhara A, Macaubas C, Prescott SLet al. Th-2-polarised immunological memory to inhalant allergens in atopics is established during infancy and early childhood. Clin Exp Allergy. 27:1997;1261-1269.
8. Prescott SL, Macaubas C, Holt BJet al. Transplacental priming of the human immune system to environmental allergens: universal skewing of initial T-cell responses towards the Th-2 cytokine profile. J Immunol. 160:1998;4730-4737.
9. Upham JW, Holt BJ, Baron-Hay MJet al. Inhalant allergen-specific T-cell reactivity is detectable in close to 100% of atopic and normal individuals: covert responses are unmasked by serum-free medium. Clin Exp Allergy. 25:1995;634-642.
10. Holt PG Primary allergic sensitisation to environmental antigens: perinatal T-cell priming as a determinant of responder phenotype in adulthood. J Exp Med. 183:1996;1297-1301.
11. Warner JA, Miles EA, Jones AC, Quint DJ, Colwell BM, Warner JO Is deficiency of interferon gamma production by allergen triggered cord blood cells a predictor of atopic eczema? Clin Exp Allergy. 24:1994;423-430.
12. Prescott SL, Macaubas C, Yabuhara Aet al. Developing patterns of T cell memory to environmental allergens in the first two years of life. Int Arch Allergy Immunol. 113:1997;75-79.
13. Piccinni M-P, Beloni L, Giannarini Let al. Abnormal production of T helper 2 cytokines interleukin-4 and interleukin-5 by T cells from newborns with atopic parents. Eur J Immunol. 26:1996;2293-2298.
14. Holt PG Postnatal maturation of immune competence during infancy and early childhood. Pediatr Allergy Immunol. 6:1995;59-70.
15. Wilson CB, Westall J, Johnston L, Lewis DB, Dover SK, Apert AR Decreased production of interferon gamma by human neonatal cells: intrinsic and regulatory deficiencies. J Clin Invest. 77:1986;860-867.
16. Holt PG, Clough JB, Holt BJet al. Genetic 'risk' for atopy is associated with delayed postnatal maturation of T-cell competence. Clin Exp Allergy. 22:1992;1093-1099.
17. Wegmann TG, Lin H, Guilbert L, Mosmann TR Bidirectional cytokine interactions in the maternal-fetal relationship: is successful pregnancy a Th2 phenomenon? Immunol Today. 14:1993;353-356.
18. Martinez FD Role of viral infections in the inception of asthma and allergies during childhood: could they be protective? Thorax. 49:1994;1189-1191.
19. Holt PG, Sly PD, Björkstén B Atopic versus infectious diseases in childhood: a question of balance? Pediatr Allergy Immunol. 8:1997;53-58.
20. Holt PG, Macaubas C Development of long term tolerance versus sensitisation to environmental allergens during the perinatal period. Curr Opin Immunol. 9:1997;782-787.
21. Sudo N, Sawamura S-A, Tanaka K, Aiba Y, Kubo C, Koga Y The requirement of intestinal bacterial flora for the development of an IgE production system fully susceptible to oral tolerance induction. J Immunol. 159:1997;1739-1745.
22. Shaheen SO, Aaby P, Hall AJet al. Measles and atopy in Guinea-Bissau. Lancet. 347:1996;1792-1796.
23. Shirakawa T, Enomoto T, Shimazu S, Hopkin JM Inverse association between tuberculin responses and atopic disorder. Science. 275:1997;77-79.