Dectin-1 activation unlocks IL12A expression and reveals the TH1 potency of neonatal dendritic cells

Journal of Allergy and Clinical Immunology

Volumn 136, Issue 5, 2015, Pages 1355-1368.e15

  Lemoine, Sébastien ^a,b   Jaron, Barbara ^a,b   Tabka, Sabrine ^a,b   Ettreiki, Chourouk ^c,f   Deriaud, Edith ^a,b   Zhivaki, Dania ^a,b,d   Le Ray, Camille ^d,e   Launay, Odile ^b,d   Majlessi, Laleh ^a   Tissieres, Pierre ^c,f   Leclerc, Claude ^a,b   Lo Man, Richard ^a,b  

^a INSTITUT PASTEUR   (France)

^b INSERM   (France)

^c ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^d UNIVERSITÉ PARIS DESCARTES   (France)

^e Maternité Port Royal ^*  (France)

^f UNIVERSITÉ PARIS SACLAY   (France)

Author keywords

adjuvant; C type lectin receptor; dendritic cells; innate immunity; Newborn; TH1; Toll like receptor

Indexed keywords

BCG VACCINE; CURDLAN; DECTIN 1; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 12P35; INTERLEUKIN 12P70; INTERLEUKIN 23; PROTEIN KINASE SYK; RAF PROTEIN; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR AGONIST; IMMUNOLOGICAL ADJUVANT; LECTIN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CD4+ T LYMPHOCYTE; CELL ACTIVATION; CELL DIFFERENTIATION; COCULTURE; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; IN VIVO STUDY; LEUKOCYTE; MONOCYTE; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NEWBORN; NONHUMAN; POLARIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; TH1 CELL; TLR SIGNALING; UMBILICAL CORD BLOOD; VACCINATION; AGONISTS; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; IMMUNOLOGY; INNATE IMMUNITY; METABOLISM; TH2 CELL;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANIMALS, NEWBORN; CELL DIFFERENTIATION; DENDRITIC CELLS; HUMANS; IMMUNITY, INNATE; INTERLEUKIN-12; INTERLEUKIN-12 SUBUNIT P35; LECTINS, C-TYPE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MONOCYTES; PROTO-ONCOGENE PROTEINS C-RAF; TH1 CELLS; TH2 CELLS; VACCINATION;

EID: 85027929730     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2015.02.030     Document Type: Article

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