Absence of functional fetal regulatory T cells in humans causes in utero organ-specific autoimmunity

Journal of Allergy and Clinical Immunology

Volumn 140, Issue 2, 2017, Pages 616-619.e7

  Allenspach, Eric J ^a,b   Finn, Laura S ^a,c   Rendi, Mara H ^a   Eken, Ahmet ^b   Singh, Akhilesh K ^b   Oukka, Mohamed ^b   Taylor, Sean D ^b   Altman, Matthew C ^a,d   Fligner, Corinne L ^a   Ochs, Hans D ^a,b   Rawlings, David J ^a,b   Torgerson, Troy R ^a,b  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b SEATTLE CHILDREN S RESEARCH INSTITUTE   (United States)

^c SEATTLE CHILDREN S HOSPITAL   (United States)

^d BENAROYA RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR3; CXCL11 CHEMOKINE; CXCL9 CHEMOKINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; LYMPHOTOXIN BETA; MACROPHAGE DERIVED CHEMOKINE; MACROPHAGE INFLAMMATORY PROTEIN 3BETA; SECONDARY LYMPHOID TISSUE CHEMOKINE; TRANSCRIPTION FACTOR FOXP3; BIOLOGICAL MARKER;

ANTIGEN SPECIFICITY; ARTICLE; AUTOIMMUNITY; AUTOPSY; B LYMPHOCYTE; CASE REPORT; CD25+ T LYMPHOCYTE; CD3+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; DIABETES MELLITUS; FETUS ECHOGRAPHY; FLUORESCENCE IN SITU HYBRIDIZATION; HISTOLOGY; HUMAN; IPEX SYNDROME; KARYOTYPE; LUNG HYPOPLASIA; MISSENSE MUTATION; NEWBORN; PHENOTYPE; PREGNANCY; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; RESPIRATORY FAILURE; RNA SEQUENCE; TERTIARY LYMPHOID STRUCTURE; X CHROMOSOME; Y CHROMOSOME; ANIMAL; ANTIBODY SPECIFICITY; DISEASE MODEL; FETUS DEVELOPMENT; IMMUNE DEFICIENCY; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; METABOLISM; MOUSE; TRANSGENIC MOUSE;

ANIMALS; AUTOIMMUNITY; BIOMARKERS; DISEASE MODELS, ANIMAL; FETAL DEVELOPMENT; HUMANS; IMMUNOHISTOCHEMISTRY; IMMUNOLOGIC DEFICIENCY SYNDROMES; INFANT, NEWBORN; MICE; MICE, TRANSGENIC; ORGAN SPECIFICITY; T-LYMPHOCYTES, REGULATORY;

EID: 85017514725     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2017.02.017     Document Type: Article

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