Functional Exhaustion Limits CD4+ and CD8+ T-Cell Responses to Congenital Cytomegalovirus Infection

Journal of Infectious Diseases

Volumn 212, Issue 3, 2015, Pages 484-494

  Huygens, Ariane ^a   Lecomte, Sandra ^a   Tackoen, Marie ^b   Olislagers, Véronique ^a   Delmarcelle, Yves ^e   Burny, Wivine ^a   Van Rysselberge, Michel ^c   Liesnard, Corinne ^b   Larsen, Martin ^f   Appay, Victor ^f   Donner, Catherine ^d   Marchant, Arnaud ^a,e,g  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^b Department of Neonatology ^*  (Belgium)

^c SAINT PIERRE UNIVERSITY HOSPITAL   (Belgium)

^d ERASME HOSPITAL   (Belgium)

^e ImmuneHealth   (Belgium)

^f PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^g Institute for Medical Immunology   (Belgium)

Author keywords

CD4 T cell; CD8 T cell; congenital infection; cytomegalovirus; exhaustion; fetus

Indexed keywords

PROGRAMMED DEATH 1 RECEPTOR; CYTOKINE; VIRUS ANTIGEN;

AGE; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL EXPANSION; CELLULAR IMMUNITY; CLINICAL TRIAL (TOPIC); CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; CYTOMEGALOVIRUS INFECTION; DISEASE ASSOCIATION; FEMALE; FETUS; HUMAN; IMMUNE RESPONSE; LYMPHOCYTE PROLIFERATION; MAJOR CLINICAL STUDY; NEWBORN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TH1 CELL; ADULT; BLOOD; COHORT ANALYSIS; CYTOLOGY; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; FETUS BLOOD; IMMUNOLOGY; PREGNANCY; PREGNANCY COMPLICATION;

ADULT; ANTIGENS, VIRAL; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; COHORT STUDIES; CYTOKINES; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; FEMALE; FETAL BLOOD; HUMANS; INFANT, NEWBORN; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS;

EID: 84939239763     PISSN: 00221899     EISSN: 15376613     Source Type: Journal    
DOI: 10.1093/infdis/jiv071     Document Type: Article

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