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Volumn 547, Issue 7663, 2017, Pages 311-317

The whole-genome landscape of medulloblastoma subtypes

(87)  Northcott, Paul A a,b   Buchhalter, Ivo a,c   Morrissy, A Sorana d   Hovestadt, Volker a   Weischenfeldt, Joachim e   Ehrenberger, Tobias f   Gröbner, Susanne a   Segura Wang, Maia h   Zichner, Thomas g   Rudneva, Vasilisa A b,g   Warnatz, Hans Jörg h   Sidiropoulos, Nikos e   Phillips, Aaron H b   Schumacher, Steven i   Kleinheinz, Kortine a   Waszak, Sebastian M g   Erkek, Serap a,g   Jones, David T W a   Worst, Barbara C a   Kool, Marcel a   more..


Author keywords

[No Author keywords available]

Indexed keywords

BRG1 PROTEIN; EPHRIN RECEPTOR A7; ISOCITRATE DEHYDROGENASE 1; PROTEIN PATCHED 1; RETINOBLASTOMA BINDING PROTEIN 2; CARRIER PROTEIN; KBTBD4 PROTEIN, HUMAN; MUSCLE PROTEIN; PRDM6 PROTEIN, HUMAN; TRANSCRIPTION FACTOR; WNT PROTEIN;

EID: 85025159196     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature22973     Document Type: Article
Times cited : (776)

References (65)
  • 1
    • 84885735554 scopus 로고    scopus 로고
    • Mutational landscape and significance across 12 major cancer types
    • Kandoth, C. et al. Mutational landscape and significance across 12 major cancer types. Nature 502, 333-339 (2013).
    • (2013) Nature , vol.502 , pp. 333-339
    • Kandoth, C.1
  • 2
    • 84885129618 scopus 로고    scopus 로고
    • Comprehensive identification of mutational cancer driver genes across 12 tumor types
    • Tamborero, D. et al. Comprehensive identification of mutational cancer driver genes across 12 tumor types. Sci. Rep. 3, 2650 (2013).
    • (2013) Sci. Rep. , vol.3 , pp. 2650
    • Tamborero, D.1
  • 3
    • 84880983541 scopus 로고    scopus 로고
    • Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma
    • Jones, D. T. et al. Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. Nat. Genet. 45, 927-932 (2013).
    • (2013) Nat. Genet. , vol.45 , pp. 927-932
    • Jones, D.T.1
  • 4
    • 84864746573 scopus 로고    scopus 로고
    • A remarkably simple genome underlies highly malignant pediatric rhabdoid cancers
    • Lee, R. S. et al. A remarkably simple genome underlies highly malignant pediatric rhabdoid cancers. J. Clin. Invest. 122, 2983-2988 (2012).
    • (2012) J. Clin. Invest. , vol.122 , pp. 2983-2988
    • Lee, R.S.1
  • 5
    • 84864419974 scopus 로고    scopus 로고
    • Dissecting the genomic complexity underlying medulloblastoma
    • Jones, D. T. et al. Dissecting the genomic complexity underlying medulloblastoma. Nature 488, 100-105 (2012).
    • (2012) Nature , vol.488 , pp. 100-105
    • Jones, D.T.1
  • 6
    • 84896096387 scopus 로고    scopus 로고
    • Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition
    • Kool, M. et al. Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition. Cancer Cell 25, 393-405 (2014).
    • (2014) Cancer Cell , vol.25 , pp. 393-405
    • Kool, M.1
  • 7
    • 84904816744 scopus 로고    scopus 로고
    • Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma
    • Northcott, P. A. et al. Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma. Nature 511, 428-434 (2014).
    • (2014) Nature , vol.511 , pp. 428-434
    • Northcott, P.A.1
  • 8
    • 84862907577 scopus 로고    scopus 로고
    • Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations
    • Rausch, T. et al. Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations. Cell 148, 59-71 (2012).
    • (2012) Cell , vol.148 , pp. 59-71
    • Rausch, T.1
  • 9
    • 84864444165 scopus 로고    scopus 로고
    • Novel mutations target distinct subgroups of medulloblastoma
    • Robinson, G. et al. Novel mutations target distinct subgroups of medulloblastoma. Nature 488, 43-48 (2012).
    • (2012) Nature , vol.488 , pp. 43-48
    • Robinson, G.1
  • 10
    • 84955506668 scopus 로고    scopus 로고
    • Divergent clonal selection dominates medulloblastoma at recurrence
    • Morrissy, A. S. et al. Divergent clonal selection dominates medulloblastoma at recurrence. Nature 529, 351-357 (2016).
    • (2016) Nature , vol.529 , pp. 351-357
    • Morrissy, A.S.1
  • 11
    • 84864425646 scopus 로고    scopus 로고
    • Subgroup-specific structural variation across 1,000 medulloblastoma genomes
    • Northcott, P. A. et al. Subgroup-specific structural variation across 1,000 medulloblastoma genomes. Nature 488, 49-56 (2012).
    • (2012) Nature , vol.488 , pp. 49-56
    • Northcott, P.A.1
  • 12
    • 84870215426 scopus 로고    scopus 로고
    • Medulloblastomics: The end of the beginning
    • Northcott, P. A. et al. Medulloblastomics: the end of the beginning. Nat. Rev. Cancer 12, 818-834 (2012).
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 818-834
    • Northcott, P.A.1
  • 13
    • 84860821444 scopus 로고    scopus 로고
    • Molecular subgroups of medulloblastoma: The current consensus
    • Taylor, M. D. et al. Molecular subgroups of medulloblastoma: the current consensus. Acta Neuropathol. 123, 465-472 (2012).
    • (2012) Acta Neuropathol. , vol.123 , pp. 465-472
    • Taylor, M.D.1
  • 14
    • 84864492215 scopus 로고    scopus 로고
    • Medulloblastoma exome sequencing uncovers subtypespecific somatic mutations
    • Pugh, T. J. et al. Medulloblastoma exome sequencing uncovers subtypespecific somatic mutations. Nature 488, 106-110 (2012).
    • (2012) Nature , vol.488 , pp. 106-110
    • Pugh, T.J.1
  • 15
    • 84878588603 scopus 로고    scopus 로고
    • Robust molecular subgrouping and copy-number profiling of medulloblastoma from small amounts of archival tumour material using high-density DNA methylation arrays
    • Hovestadt, V. et al. Robust molecular subgrouping and copy-number profiling of medulloblastoma from small amounts of archival tumour material using high-density DNA methylation arrays. Acta Neuropathol. 125, 913-916 (2013).
    • (2013) Acta Neuropathol. , vol.125 , pp. 913-916
    • Hovestadt, V.1
  • 16
    • 84882837534 scopus 로고    scopus 로고
    • Signatures of mutational processes in human cancer
    • Alexandrov, L. B. et al. Signatures of mutational processes in human cancer. Nature 500, 415-421 (2013).
    • (2013) Nature , vol.500 , pp. 415-421
    • Alexandrov, L.B.1
  • 17
    • 84963562984 scopus 로고    scopus 로고
    • Biallelic BRCA2 mutations shape the somatic mutational landscape of aggressive prostate tumors
    • Decker, B. et al. Biallelic BRCA2 mutations shape the somatic mutational landscape of aggressive prostate tumors. Am. J. Hum. Genet. 98, 818-829 (2016).
    • (2016) Am. J. Hum. Genet. , vol.98 , pp. 818-829
    • Decker, B.1
  • 18
    • 84863922124 scopus 로고    scopus 로고
    • Comprehensive molecular characterization of human colon and rectal cancer
    • The Cancer Genome Atlas Network.
    • The Cancer Genome Atlas Network. Comprehensive molecular characterization of human colon and rectal cancer. Nature 487, 330-337 (2012).
    • (2012) Nature , vol.487 , pp. 330-337
  • 19
    • 84877254190 scopus 로고    scopus 로고
    • Integrated genomic characterization of endometrial carcinoma
    • Kandoth, C. et al. Integrated genomic characterization of endometrial carcinoma. Nature 497, 67-73 (2013).
    • (2013) Nature , vol.497 , pp. 67-73
    • Kandoth, C.1
  • 20
    • 84880507665 scopus 로고    scopus 로고
    • Mutational heterogeneity in cancer and the search for new cancer-associated genes
    • Lawrence, M. S. et al. Mutational heterogeneity in cancer and the search for new cancer-associated genes. Nature 499, 214-218 (2013).
    • (2013) Nature , vol.499 , pp. 214-218
    • Lawrence, M.S.1
  • 21
    • 84864598664 scopus 로고    scopus 로고
    • MuSiC: Identifying mutational significance in cancer genomes
    • Dees, N. D. et al. MuSiC: identifying mutational significance in cancer genomes. Genome Res. 22, 1589-1598 (2012).
    • (2012) Genome Res. , vol.22 , pp. 1589-1598
    • Dees, N.D.1
  • 22
    • 84887032986 scopus 로고    scopus 로고
    • IntOGen-mutations identifies cancer drivers across tumor types
    • Gonzalez-Perez, A. et al. IntOGen-mutations identifies cancer drivers across tumor types. Nat. Methods 10, 1081-1082 (2013).
    • (2013) Nat. Methods , vol.10 , pp. 1081-1082
    • Gonzalez-Perez, A.1
  • 23
    • 63449115501 scopus 로고    scopus 로고
    • Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma
    • Northcott, P. A. et al. Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma. Nat. Genet. 41, 465-472 (2009).
    • (2009) Nat. Genet. , vol.41 , pp. 465-472
    • Northcott, P.A.1
  • 24
    • 79251629946 scopus 로고    scopus 로고
    • The genetic landscape of the childhood cancer medulloblastoma
    • Parsons, D. W. et al. The genetic landscape of the childhood cancer medulloblastoma. Science 331, 435-439 (2011).
    • (2011) Science , vol.331 , pp. 435-439
    • Parsons, D.W.1
  • 25
    • 0028350888 scopus 로고
    • Germ-line and somatic mutations of the APC gene in patients with Turcot syndrome and analysis of APC mutations in brain tumors
    • Mori, T. et al. Germ-line and somatic mutations of the APC gene in patients with Turcot syndrome and analysis of APC mutations in brain tumors. Genes Chromosom. Cancer 9, 168-172 (1994).
    • (1994) Genes Chromosom. Cancer , vol.9 , pp. 168-172
    • Mori, T.1
  • 26
    • 77957955244 scopus 로고    scopus 로고
    • Epigenetic antagonism between polycomb and SWI/SNF complexes during oncogenic transformation
    • Wilson, B. G. et al. Epigenetic antagonism between polycomb and SWI/SNF complexes during oncogenic transformation. Cancer Cell 18, 316-328 (2010).
    • (2010) Cancer Cell , vol.18 , pp. 316-328
    • Wilson, B.G.1
  • 27
    • 77952108366 scopus 로고    scopus 로고
    • Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma
    • Noushmehr, H. et al. Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma. Cancer Cell 17, 510-522 (2010).
    • (2010) Cancer Cell , vol.17 , pp. 510-522
    • Noushmehr, H.1
  • 28
    • 84955561447 scopus 로고    scopus 로고
    • Molecular profiling reveals biologically discrete subsets and pathways of progression in diffuse Glioma
    • Ceccarelli, M. et al. Molecular profiling reveals biologically discrete subsets and pathways of progression in diffuse Glioma. Cell 164, 550-563 (2016).
    • (2016) Cell , vol.164 , pp. 550-563
    • Ceccarelli, M.1
  • 29
    • 84923165577 scopus 로고    scopus 로고
    • Deep sequencing identifies IDH1 R132S mutation in adult medulloblastoma
    • Snuderl, M. et al. Deep sequencing identifies IDH1 R132S mutation in adult medulloblastoma. J. Clin. Oncol. 33, e27-e31 (2015).
    • (2015) J. Clin. Oncol. , vol.33 , pp. e27-e31
    • Snuderl, M.1
  • 30
    • 7444224783 scopus 로고    scopus 로고
    • Notch1 and Notch2 have opposite effects on embryonal brain tumor growth
    • Fan, X. et al. Notch1 and Notch2 have opposite effects on embryonal brain tumor growth. Cancer Res. 64, 7787-7793 (2004).
    • (2004) Cancer Res. , vol.64 , pp. 7787-7793
    • Fan, X.1
  • 31
    • 63449135077 scopus 로고    scopus 로고
    • MicroRNA-199b-5p impairs cancer stem cells through negative regulation of HES1 in medulloblastoma
    • Garzia, L. et al. MicroRNA-199b-5p impairs cancer stem cells through negative regulation of HES1 in medulloblastoma. PLoS One 4, e4998 (2009).
    • (2009) PLoS One , vol.4 , pp. e4998
    • Garzia, L.1
  • 32
    • 84957573186 scopus 로고    scopus 로고
    • Active medulloblastoma enhancers reveal subgroup-specific cellular origins
    • Lin, C. Y. et al. Active medulloblastoma enhancers reveal subgroup-specific cellular origins. Nature 530, 57-62 (2016).
    • (2016) Nature , vol.530 , pp. 57-62
    • Lin, C.Y.1
  • 33
    • 79954991010 scopus 로고    scopus 로고
    • Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome
    • Cho, Y. J. et al. Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome. J. Clin. Oncol. 29, 1424-1430 (2011).
    • (2011) J. Clin. Oncol. , vol.29 , pp. 1424-1430
    • Cho, Y.J.1
  • 34
    • 52449119078 scopus 로고    scopus 로고
    • Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features
    • Kool, M. et al. Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features. PLoS One 3, e3088 (2008).
    • (2008) PLoS One , vol.3 , pp. e3088
    • Kool, M.1
  • 35
    • 79955034739 scopus 로고    scopus 로고
    • Medulloblastoma comprises four distinct molecular variants
    • Northcott, P. A. et al. Medulloblastoma comprises four distinct molecular variants. J. Clin. Oncol. 29, 1408-1414 (2011).
    • (2011) J. Clin. Oncol. , vol.29 , pp. 1408-1414
    • Northcott, P.A.1
  • 36
    • 84875152063 scopus 로고    scopus 로고
    • Structural basis for Cul3 protein assembly with the BTB-Kelch family of E3 ubiquitin ligases
    • Canning, P. et al. Structural basis for Cul3 protein assembly with the BTB-Kelch family of E3 ubiquitin ligases. J. Biol. Chem. 288, 7803-7814 (2013).
    • (2013) J. Biol. Chem. , vol.288 , pp. 7803-7814
    • Canning, P.1
  • 37
    • 84997610090 scopus 로고    scopus 로고
    • Pan-cancer analysis of somatic copy-number alterations implicates IRS4 and IGF2 in enhancer hijacking
    • Weischenfeldt, J. et al. Pan-cancer analysis of somatic copy-number alterations implicates IRS4 and IGF2 in enhancer hijacking. Nat. Genet. 49, 65-74 (2017).
    • (2017) Nat. Genet. , vol.49 , pp. 65-74
    • Weischenfeldt, J.1
  • 38
    • 33645239290 scopus 로고    scopus 로고
    • PRISM/PRDM6, a transcriptional repressor that promotes the proliferative gene program in smooth muscle cells
    • Davis, C. A. et al. PRISM/PRDM6, a transcriptional repressor that promotes the proliferative gene program in smooth muscle cells. Mol. Cell. Biol. 26, 2626-2636 (2006).
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 2626-2636
    • Davis, C.A.1
  • 39
    • 84966687479 scopus 로고    scopus 로고
    • The 2016 World Health Organization Classification of Tumors of the Central Nervous System: A summary
    • Louis, D. N. et al. The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary. Acta Neuropathol. 131, 803-820 (2016).
    • (2016) Acta Neuropathol. , vol.131 , pp. 803-820
    • Louis, D.N.1
  • 40
    • 84899684426 scopus 로고    scopus 로고
    • Cytogenetic prognostication within medulloblastoma subgroups
    • Shih, D. J. et al. Cytogenetic prognostication within medulloblastoma subgroups. J. Clin. Oncol. 32, 886-896 (2014).
    • (2014) J. Clin. Oncol. , vol.32 , pp. 886-896
    • Shih, D.J.1
  • 42
    • 68549104404 scopus 로고    scopus 로고
    • The Sequence Alignment/Map format and SAMtools
    • Li, H. et al. The Sequence Alignment/Map format and SAMtools. Bioinformatics 25, 2078-2079 (2009).
    • (2009) Bioinformatics , vol.25 , pp. 2078-2079
    • Li, H.1
  • 43
    • 77956534324 scopus 로고    scopus 로고
    • AnOVAR: Functional annotation of genetic variants from high-throughput sequencing data
    • Wang, K., Li, M. & Hakonarson, H. AnOVAR: functional annotation of genetic variants from high-throughput sequencing data. Nucleic Acids Res. 38, e164 (2010).
    • (2010) Nucleic Acids Res. , vol.38 , pp. e164
    • Wang, K.1    Li, M.2    Hakonarson, H.3
  • 44
    • 84905576523 scopus 로고    scopus 로고
    • Integrating mapping-, assembly-and haplotype-based approaches for calling variants in clinical sequencing applications
    • Rimmer, A. et al. Integrating mapping-, assembly-and haplotype-based approaches for calling variants in clinical sequencing applications. Nat. Genet. 46, 912-918 (2014).
    • (2014) Nat. Genet. , vol.46 , pp. 912-918
    • Rimmer, A.1
  • 45
    • 84949564442 scopus 로고    scopus 로고
    • A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing
    • Alioto, T. S. et al. A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing. Nat. Commun. 6, 10001 (2015).
    • (2015) Nat. Commun. , vol.6 , pp. 10001
    • Alioto, T.S.1
  • 46
    • 84866440781 scopus 로고    scopus 로고
    • DELLY: Structural variant discovery by integrated paired-end and split-read analysis
    • Rausch, T. et al. DELLY: structural variant discovery by integrated paired-end and split-read analysis. Bioinformatics 28, i333-i339 (2012).
    • (2012) Bioinformatics , vol.28 , pp. i333-i339
    • Rausch, T.1
  • 47
    • 0035173378 scopus 로고    scopus 로고
    • DbSNP: The NCBI database of genetic variation
    • Sherry, S. T. et al. dbSNP: the NCBI database of genetic variation. Nucleic Acids Res. 29, 308-311 (2001).
    • (2001) Nucleic Acids Res. , vol.29 , pp. 308-311
    • Sherry, S.T.1
  • 48
    • 67651222400 scopus 로고    scopus 로고
    • A flexible and accurate genotype imputation method for the next generation of genome-wide association studies
    • Howie, B. N., Donnelly, P. & Marchini, J. A flexible and accurate genotype imputation method for the next generation of genome-wide association studies. PLoS Genet. 5, e1000529 (2009).
    • (2009) PLoS Genet. , vol.5 , pp. e1000529
    • Howie, B.N.1    Donnelly, P.2    Marchini, J.3
  • 49
    • 79960393165 scopus 로고    scopus 로고
    • Parent-specific copy number in paired tumor-normal studies using circular binary segmentation
    • Olshen, A. B. et al. Parent-specific copy number in paired tumor-normal studies using circular binary segmentation. Bioinformatics 27, 2038-2046 (2011).
    • (2011) Bioinformatics , vol.27 , pp. 2038-2046
    • Olshen, A.B.1
  • 50
    • 84959151000 scopus 로고    scopus 로고
    • Atypical teratoid/rhabdoid tumors are comprised of three epigenetic subgroups with distinct enhancer landscapes
    • Johann, P. D. et al. Atypical teratoid/rhabdoid tumors are comprised of three epigenetic subgroups with distinct enhancer landscapes. Cancer Cell 29, 379-393 (2016).
    • (2016) Cancer Cell , vol.29 , pp. 379-393
    • Johann, P.D.1
  • 51
    • 79955166265 scopus 로고    scopus 로고
    • GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers
    • Mermel, C. H. et al. GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers. Genome Biol. 12, R41 (2011).
    • (2011) Genome Biol. , vol.12 , pp. R41
    • Mermel, C.H.1
  • 53
    • 84897548625 scopus 로고    scopus 로고
    • Minfi: A flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays
    • Aryee, M. J. et al. Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays. Bioinformatics 30, 1363-1369 (2014).
    • (2014) Bioinformatics , vol.30 , pp. 1363-1369
    • Aryee, M.J.1
  • 54
    • 84861095603 scopus 로고    scopus 로고
    • Topological domains in mammalian genomes identified by analysis of chromatin interactions
    • Dixon, J. R. et al. Topological domains in mammalian genomes identified by analysis of chromatin interactions. Nature 485, 376-380 (2012).
    • (2012) Nature , vol.485 , pp. 376-380
    • Dixon, J.R.1
  • 55
    • 77951770756 scopus 로고    scopus 로고
    • BEDTools: A flexible suite of utilities for comparing genomic features
    • Quinlan, A. R. & Hall, I. M. BEDTools: a flexible suite of utilities for comparing genomic features. Bioinformatics 26, 841-842 (2010).
    • (2010) Bioinformatics , vol.26 , pp. 841-842
    • Quinlan, A.R.1    Hall, I.M.2
  • 56
    • 84969945169 scopus 로고    scopus 로고
    • Fast and efficient QTL mapper for thousands of molecular phenotypes
    • Ongen, H., Buil, A., Brown, A. A., Dermitzakis, E. T. & Delaneau, O. Fast and efficient QTL mapper for thousands of molecular phenotypes. Bioinformatics 32, 1479-1485 (2015).
    • (2015) Bioinformatics , vol.32 , pp. 1479-1485
    • Ongen, H.1    Buil, A.2    Brown, A.A.3    Dermitzakis, E.T.4    Delaneau, O.5
  • 57
    • 33746512512 scopus 로고    scopus 로고
    • Principal components analysis corrects for stratification in genome-wide association studies
    • Price, A. L. et al. Principal components analysis corrects for stratification in genome-wide association studies. Nat. Genet. 38, 904-909 (2006).
    • (2006) Nat. Genet. , vol.38 , pp. 904-909
    • Price, A.L.1
  • 58
    • 84964720815 scopus 로고    scopus 로고
    • Network-Based interpretation of diverse high-throughput datasets through the Omics Integrator software package
    • Tuncbag, N. et al. Network-Based interpretation of diverse high-throughput datasets through the Omics Integrator software package. PLOS Comput. Biol. 12, e1004879 (2016).
    • (2016) PLOS Comput. Biol. , vol.12 , pp. e1004879
    • Tuncbag, N.1
  • 59
    • 54949127160 scopus 로고    scopus 로고
    • IRefIndex: A consolidated protein interaction database with provenance
    • Razick, S., Magklaras, G. & Donaldson, I. M. iRefIndex: a consolidated protein interaction database with provenance. BMC Bioinformatics 9, 405 (2008).
    • (2008) BMC Bioinformatics , vol.9 , pp. 405
    • Razick, S.1    Magklaras, G.2    Donaldson, I.M.3
  • 60
    • 84876148784 scopus 로고    scopus 로고
    • HMDB 3.0 - The Human Metabolome Database in 2013
    • Wishart, D. S. et al. HMDB 3.0 - The Human Metabolome Database in 2013. Nucleic Acids Res. 41, D801-D807 (2013).
    • (2013) Nucleic Acids Res. , vol.41 , pp. D801-D807
    • Wishart, D.S.1
  • 61
    • 84877315835 scopus 로고    scopus 로고
    • A community-driven global reconstruction of human metabolism
    • Thiele, I. et al. A community-driven global reconstruction of human metabolism. Nat. Biotechnol. 31, 419-425 (2013).
    • (2013) Nat. Biotechnol. , vol.31 , pp. 419-425
    • Thiele, I.1
  • 62
    • 38449101120 scopus 로고    scopus 로고
    • Integration of biological networks and gene expression data using Cytoscape
    • Cline, M. S. et al. Integration of biological networks and gene expression data using Cytoscape. Nat. Protocols 2, 2366-2382 (2007).
    • (2007) Nat. Protocols , vol.2 , pp. 2366-2382
    • Cline, M.S.1
  • 63
    • 84938567345 scopus 로고    scopus 로고
    • CoMEt: A statistical approach to identify combinations of mutually exclusive alterations in cancer
    • Leiserson, M. D., Wu, H. T., Vandin, F. & Raphael, B. J. CoMEt: a statistical approach to identify combinations of mutually exclusive alterations in cancer. Genome Biol. 16, 160 (2015).
    • (2015) Genome Biol. , vol.16 , pp. 160
    • Leiserson, M.D.1    Wu, H.T.2    Vandin, F.3    Raphael, B.J.4
  • 64
    • 84904815625 scopus 로고    scopus 로고
    • SWISS-MODEL: Modelling protein tertiary and quaternary structure using evolutionary information
    • Biasini, M. et al. SWISS-MODEL: modelling protein tertiary and quaternary structure using evolutionary information. Nucleic Acids Res. 42, W252-W258 (2014).
    • (2014) Nucleic Acids Res. , vol.42 , pp. W252-W258
    • Biasini, M.1
  • 65
    • 84871809302 scopus 로고    scopus 로고
    • STAR: Ultrafast universal RNA-seq aligner
    • Dobin, A. et al. STAR: ultrafast universal RNA-seq aligner. Bioinformatics 29, 15-21 (2013).
    • (2013) Bioinformatics , vol.29 , pp. 15-21
    • Dobin, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.