-
1
-
-
80955180712
-
A phase i pharmacokinetic trial of sonic hedgehog (SHH) antagonist GDC-0449 in pediatric patients with recurrent or refractory medulloblastoma: A pediatric brain tumor consortium study (PBTC 25)
-
Gajjar A, Stewart CF, Ellison DW et al (2010) A phase I pharmacokinetic trial of sonic hedgehog (SHH) antagonist GDC-0449 in pediatric patients with recurrent or refractory medulloblastoma: a pediatric brain tumor consortium study (PBTC 25). J Clin Oncol 28(18s):Abstr. CRA9501
-
(2010)
J Clin Oncol
, vol.28
, Issue.18 S
, pp. 9501
-
-
Gajjar, A.1
Stewart, C.F.2
Ellison, D.W.3
-
2
-
-
84877605428
-
A phase I/II study of LDE225, a smoothened (Smo) antagonist, in pediatric patients with recurrent medulloblastoma (MB) or other solid tumors
-
Geoerger B, Aerts I, Casanova M et al (2012) A phase I/II study of LDE225, a smoothened (Smo) antagonist, in pediatric patients with recurrent medulloblastoma (MB) or other solid tumors. J Clin Oncol 30(Suppl.):Abstr. 9519
-
(2012)
J Clin Oncol
, vol.30
, Issue.SUPPL.
, pp. 9519
-
-
Geoerger, B.1
Aerts, I.2
Casanova, M.3
-
3
-
-
84864419974
-
Dissecting the genomic complexity underlying medulloblastoma
-
10.1038/nature11284 22832583 10.1038/nature11284 1:CAS:528: DC%2BC38XhtFWmt7bK
-
Jones DTW, Jager N, Kool M et al (2012) Dissecting the genomic complexity underlying medulloblastoma. Nature 488(7409):100-105. doi: 10.1038/nature11284
-
(2012)
Nature
, vol.488
, Issue.7409
, pp. 100-105
-
-
Jones, D.T.W.1
Jager, N.2
Kool, M.3
-
4
-
-
84863393028
-
Molecular subgroups of medulloblastoma: An international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas
-
10.1007/s00401-012-0958-8 22358457 10.1007/s00401-012-0958-8 1:CAS:528:DC%2BC38XktlaqsL4%3D
-
Kool M, Korshunov A, Remke M et al (2012) Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas. Acta Neuropathol 123(4):473-484. doi: 10.1007/s00401-012-0958- 8
-
(2012)
Acta Neuropathol
, vol.123
, Issue.4
, pp. 473-484
-
-
Kool, M.1
Korshunov, A.2
Remke, M.3
-
5
-
-
84868198427
-
Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia
-
10.1038/ng.2443 23064414 10.1038/ng.2443 1:CAS:528:DC%2BC38XhsV2rsLfI
-
Kulis M, Heath S, Bibikova M et al (2012) Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia. Nat Genet 44(11):1236-1242. doi: 10.1038/ng.2443
-
(2012)
Nat Genet
, vol.44
, Issue.11
, pp. 1236-1242
-
-
Kulis, M.1
Heath, S.2
Bibikova, M.3
-
6
-
-
84870215426
-
Medulloblastomics: The end of the beginning
-
10.1038/nrc3410 23175120 10.1038/nrc3410 1:CAS:528:DC%2BC38Xhslags7jJ
-
Northcott PA, Jones DTW, Kool M et al (2012) Medulloblastomics: the end of the beginning. Nat Rev Cancer 12(12):818-834. doi: 10.1038/nrc3410
-
(2012)
Nat Rev Cancer
, vol.12
, Issue.12
, pp. 818-834
-
-
Northcott, P.A.1
Jones, D.T.W.2
Kool, M.3
-
7
-
-
79955034739
-
Medulloblastoma comprises four distinct molecular variants
-
10.1200/JCO.2009.27.4324 20823417 10.1200/JCO.2009.27.4324
-
Northcott PA, Korshunov A, Witt H et al (2011) Medulloblastoma comprises four distinct molecular variants. J Clin Oncol 29(11):1408-1414. doi: 10.1200/JCO.2009.27.4324
-
(2011)
J Clin Oncol
, vol.29
, Issue.11
, pp. 1408-1414
-
-
Northcott, P.A.1
Korshunov, A.2
Witt, H.3
-
8
-
-
84864425646
-
Subgroup-specific structural variation across 1,000 medulloblastoma genomes
-
10.1038/nature11327 22832581 10.1038/nature11327 1:CAS:528: DC%2BC38XhtFWmt73N
-
Northcott PA, Shih DJ, Peacock J et al (2012) Subgroup-specific structural variation across 1,000 medulloblastoma genomes. Nature 488(7409):49-56. doi: 10.1038/nature11327
-
(2012)
Nature
, vol.488
, Issue.7409
, pp. 49-56
-
-
Northcott, P.A.1
Shih, D.J.2
Peacock, J.3
-
9
-
-
84862680481
-
Rapid, reliable, and reproducible molecular sub-grouping of clinical medulloblastoma samples
-
10.1007/s00401-011-0899-7 22057785 10.1007/s00401-011-0899-7 1:CAS:528:DC%2BC38Xktlaru70%3D
-
Northcott PA, Shih DJ, Remke M et al (2012) Rapid, reliable, and reproducible molecular sub-grouping of clinical medulloblastoma samples. Acta Neuropathol 123(4):615-626. doi: 10.1007/s00401-011-0899-7
-
(2012)
Acta Neuropathol
, vol.123
, Issue.4
, pp. 615-626
-
-
Northcott, P.A.1
Shih, D.J.2
Remke, M.3
-
10
-
-
77952108366
-
Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma
-
10.1016/j.ccr.2010.03.017 20399149 10.1016/j.ccr.2010.03.017 1:CAS:528:DC%2BC3cXmslKqsr0%3D
-
Noushmehr H, Weisenberger DJ, Diefes K et al (2010) Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma. Cancer Cell 17(5):510-522. doi: 10.1016/j.ccr.2010.03.017
-
(2010)
Cancer Cell
, vol.17
, Issue.5
, pp. 510-522
-
-
Noushmehr, H.1
Weisenberger, D.J.2
Diefes, K.3
-
11
-
-
84862907577
-
Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations
-
10.1016/j.cell.2011.12.013 22265402 10.1016/j.cell.2011.12.013 1:CAS:528:DC%2BC38XhtFKgtrg%3D
-
Rausch T, Jones DTW, Zapatka M et al (2012) Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations. Cell 148(1-2):59-71. doi: 10.1016/j.cell.2011.12.013
-
(2012)
Cell
, vol.148
, Issue.1-2
, pp. 59-71
-
-
Rausch, T.1
Jones, D.T.W.2
Zapatka, M.3
-
12
-
-
84878874877
-
DNA methylation profiling of medulloblastoma allows robust subclassification and improved outcome prediction using formalin-fixed biopsies
-
10.1007/s00401-012-1077-2 23291781 10.1007/s00401-012-1077-2 1:CAS:528:DC%2BC3sXjtFGhu7c%3D
-
Schwalbe EC, Williamson D, Lindsey JC et al (2013) DNA methylation profiling of medulloblastoma allows robust subclassification and improved outcome prediction using formalin-fixed biopsies. Acta Neuropathol 125(3):359-371. doi: 10.1007/s00401-012-1077-2
-
(2013)
Acta Neuropathol
, vol.125
, Issue.3
, pp. 359-371
-
-
Schwalbe, E.C.1
Williamson, D.2
Lindsey, J.C.3
-
13
-
-
78650959663
-
Massive genomic rearrangement acquired in a single catastrophic event during cancer development
-
10.1016/j.cell.2010.11.055 21215367 10.1016/j.cell.2010.11.055 1:CAS:528:DC%2BC3MXksFGjug%3D%3D
-
Stephens PJ, Greenman CD, Fu B et al (2011) Massive genomic rearrangement acquired in a single catastrophic event during cancer development. Cell 144(1):27-40. doi: 10.1016/j.cell.2010.11.055
-
(2011)
Cell
, vol.144
, Issue.1
, pp. 27-40
-
-
Stephens, P.J.1
Greenman, C.D.2
Fu, B.3
-
14
-
-
84867606428
-
Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma
-
10.1016/j.ccr.2012.08.024 23079654 10.1016/j.ccr.2012.08.024 1:CAS:528:DC%2BC38XhsFWhsr%2FF
-
Sturm D, Witt H, Hovestadt V et al (2012) Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma. Cancer Cell 22(4):425-437. doi: 10.1016/j.ccr.2012.08.024
-
(2012)
Cancer Cell
, vol.22
, Issue.4
, pp. 425-437
-
-
Sturm, D.1
Witt, H.2
Hovestadt, V.3
-
15
-
-
84860821444
-
Molecular subgroups of medulloblastoma: The current consensus
-
10.1007/s00401-011-0922-z 22134537 10.1007/s00401-011-0922-z 1:CAS:528:DC%2BC38Xktlaru7Y%3D
-
Taylor MD, Northcott PA, Korshunov A et al (2012) Molecular subgroups of medulloblastoma: the current consensus. Acta Neuropathol 123(4):465-472. doi: 10.1007/s00401-011-0922-z
-
(2012)
Acta Neuropathol
, vol.123
, Issue.4
, pp. 465-472
-
-
Taylor, M.D.1
Northcott, P.A.2
Korshunov, A.3
|