-
1
-
-
79551686425
-
Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro
-
Spence, J.R. et al. Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro. Nature 470, 105-109 (2011).
-
(2011)
Nature
, vol.470
, pp. 105-109
-
-
Spence, J.R.1
-
2
-
-
84918561297
-
Modelling human development and disease in pluripotent stem-cell-derived gastric organoids
-
McCracken, K.W. et al. Modelling human development and disease in pluripotent stem-cell-derived gastric organoids. Nature 516, 400-404 (2014).
-
(2014)
Nature
, vol.516
, pp. 400-404
-
-
McCracken, K.W.1
-
3
-
-
84884414984
-
Cerebral organoids model human brain development and microcephaly
-
Lancaster, M.A. et al. Cerebral organoids model human brain development and microcephaly. Nature 501, 373-379 (2013).
-
(2013)
Nature
, vol.501
, pp. 373-379
-
-
Lancaster, M.A.1
-
4
-
-
84881184980
-
Vascularized and functional human liver from an ipsc-derived organ bud transplant
-
Takebe, T. et al. Vascularized and functional human liver from an iPSC-derived organ bud transplant. Nature 499, 481-484 (2013).
-
(2013)
Nature
, vol.499
, pp. 481-484
-
-
Takebe, T.1
-
5
-
-
84925459906
-
In vitro generation of human pluripotent stem cell derived lung organoids
-
Dye, B.R. et al. In vitro generation of human pluripotent stem cell derived lung organoids. eLife 4, e05098 (2015).
-
(2015)
ELife
, vol.4
, pp. e05098
-
-
Dye, B.R.1
-
6
-
-
84946215806
-
Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell-And patient-derived tumor organoids
-
Huang, L. et al. Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell-And patient-derived tumor organoids. Nat. Med. 21, 1364-1371 (2015).
-
(2015)
Nat. Med
, vol.21
, pp. 1364-1371
-
-
Huang, L.1
-
7
-
-
82855161367
-
Wnt signaling specifies and patterns intestinal endoderm
-
Sherwood, R.I., Maehr, R., Mazzoni, E.O. & Melton, D.A. Wnt signaling specifies and patterns intestinal endoderm. Mech. Dev. 128, 387-400 (2011).
-
(2011)
Mech. Dev
, vol.128
, pp. 387-400
-
-
Sherwood, R.I.1
Maehr, R.2
Mazzoni, E.O.3
Melton, D.A.4
-
8
-
-
0032714049
-
Coordinated expression of 3? Hox genes during murine embryonal gut development: An enteric hox code
-
Pitera, J.E., Smith, V.V., Thorogood, P. & Milla, P.J. Coordinated expression of 3? hox genes during murine embryonal gut development: an enteric Hox code. Gastroenterology 117, 1339-1351 (1999).
-
(1999)
Gastroenterology
, vol.117
, pp. 1339-1351
-
-
Pitera, J.E.1
Smith, V.V.2
Thorogood, P.3
Milla, P.J.4
-
9
-
-
0032416376
-
Carbonic anhydrase i and II as a differentiation marker of human and rat colonic enterocytes
-
Bekku, S. et al. Carbonic anhydrase I and II as a differentiation marker of human and rat colonic enterocytes. Res. Exp. Med. (Berl.) 198, 175-185 (1998).
-
(1998)
Res. Exp. Med. (Berl
, vol.198
, pp. 175-185
-
-
Bekku, S.1
-
10
-
-
85023638929
-
-
The Human Protein Atlas, n.d. available at
-
The Human Protein Atlas. CA4 (The Human Protein Atlas, n.d.); available at http://www.proteinatlas.org/ENSG00000167434-CA4/tissue/colon.
-
CA4 (The Human Protein Atlas
-
-
-
11
-
-
18644376279
-
Beta-catenin and tcf mediate cell positioning in the intestinal epithelium by controlling the expression of ephb/ephrinb
-
Batlle, E. et al. Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB. Cell 111, 251-263 (2002).
-
(2002)
Cell
, vol.111
, pp. 251-263
-
-
Batlle, E.1
-
12
-
-
0344975376
-
Villin the major microfilament-Associated protein of the intestinal microvillus
-
Bretscher, A. & Weber, K. Villin: the major microfilament-Associated protein of the intestinal microvillus. Proc. Natl. Acad. Sci. USA 76, 2321-2325 (1979).
-
(1979)
Proc. Natl. Acad. Sci. USA
, vol.76
, pp. 2321-2325
-
-
Bretscher, A.1
Weber, K.2
-
13
-
-
0032126408
-
The muc2 gene product: A human intestinal mucin
-
Allen, A., Hutton, D.A. & Pearson, J.P. The MUC2 gene product: a human intestinal mucin. Int. J. Biochem. Cell Biol. 30, 797-801 (1998).
-
(1998)
Int. J. Biochem. Cell Biol
, vol.30
, pp. 797-801
-
-
Allen, A.1
Hutton, D.A.2
Pearson, J.P.3
-
14
-
-
0020602664
-
Chromogranin a immunohistology reveals its universal occurrence in normal polypeptide hormone producing endocrine glands
-
O'Connor, D.T., Burton, D. & Deftos, L.J. Chromogranin A: immunohistology reveals its universal occurrence in normal polypeptide hormone producing endocrine glands. Life Sci. 33, 1657-1663 (1983).
-
(1983)
Life Sci
, vol.33
, pp. 1657-1663
-
-
O'Connor, D.T.1
Burton, D.2
Deftos, L.J.3
-
15
-
-
0026782321
-
Immunocytochemical studies suggest two pathways for enteroendocrine cell differentiation in the colon
-
Roth, K.A., Kim, S. & Gordon, J.I. Immunocytochemical studies suggest two pathways for enteroendocrine cell differentiation in the colon. Am. J. Physiol. 263, G174-G180 (1992).
-
(1992)
Am. J. Physiol
, vol.263
, pp. G174-G180
-
-
Roth, K.A.1
Kim, S.2
Gordon, J.I.3
-
16
-
-
0021056404
-
5-HT metabolism in the intestinal wall of the rat-I. The mucosa
-
Legay, C., Faudon, M., Héry, F. & Ternaux, J.P. 5-HT metabolism in the intestinal wall of the rat-I. The mucosa. Neurochem. Int. 5, 721-727 (1983).
-
(1983)
Neurochem. Int
, vol.5
, pp. 721-727
-
-
Legay, C.1
Faudon, M.2
Héry, F.3
Ternaux, J.P.4
-
17
-
-
84862946094
-
The intestinal stem cell markers bmi1 and lgr5 identify two functionally distinct populations
-
Yan, K.S. et al. The intestinal stem cell markers Bmi1 and Lgr5 identify two functionally distinct populations. Proc. Natl. Acad. Sci. USA 109, 466-471 (2012).
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 466-471
-
-
Yan, K.S.1
-
18
-
-
83255193921
-
Interconversion between intestinal stem cell populations in distinct niches
-
Takeda, N. et al. Interconversion between intestinal stem cell populations in distinct niches. Science 334, 1420-1424 (2011).
-
(2011)
Science
, vol.334
, pp. 1420-1424
-
-
Takeda, N.1
-
19
-
-
0037011171
-
Neurogenin3 is differentially required for endocrine cell fate specification in the intestinal and gastric epithelium
-
Jenny, M. et al. Neurogenin3 is differentially required for endocrine cell fate specification in the intestinal and gastric epithelium. EMBO J. 21, 6338-6347 (2002).
-
(2002)
EMBO J
, vol.21
, pp. 6338-6347
-
-
Jenny, M.1
-
20
-
-
0025354008
-
Identification of protein it of the intestinal cytoskeleton as a novel type i cytokeratin with unusual properties and expression patterns
-
Moll, R., Schiller, D.L. & Franke, W.W. Identification of protein IT of the intestinal cytoskeleton as a novel type I cytokeratin with unusual properties and expression patterns. J. Cell Biol. 111, 567-580 (1990).
-
(1990)
J. Cell Biol
, vol.111
, pp. 567-580
-
-
Moll, R.1
Schiller, D.L.2
Franke, W.W.3
-
21
-
-
79952397747
-
Generation of anterior foregut endoderm from human embryonic and induced pluripotent stem cells
-
Green, M.D. et al. Generation of anterior foregut endoderm from human embryonic and induced pluripotent stem cells. Nat. Biotechnol. 29, 267-272 (2011).
-
(2011)
Nat. Biotechnol
, vol.29
, pp. 267-272
-
-
Green, M.D.1
-
22
-
-
84983134468
-
Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells
-
Rezania, A. et al. Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells. Nat. Biotechnol. 32, 1121-1133 (2014).
-
(2014)
Nat. Biotechnol
, vol.32
, pp. 1121-1133
-
-
Rezania, A.1
-
23
-
-
52249098253
-
Gata4 mediates gene repression in the mature mouse small intestine through interactions with friend of gata (fog) cofactors
-
Beuling, E. et al. GATA4 mediates gene repression in the mature mouse small intestine through interactions with friend of GATA (FOG) cofactors. Dev. Biol. 322, 179-189 (2008).
-
(2008)
Dev. Biol
, vol.322
, pp. 179-189
-
-
Beuling, E.1
-
24
-
-
84902144564
-
Human intestinal tissue with adult stem cell properties derived from pluripotent stem cells
-
Forster, R. et al. Human intestinal tissue with adult stem cell properties derived from pluripotent stem cells. Stem Cell Reports 2, 838-852 (2014).
-
(2014)
Stem Cell Reports
, vol.2
, pp. 838-852
-
-
Forster, R.1
-
25
-
-
84971516758
-
A colorectal tumor organoid library demonstrates progressive loss of niche factor requirements during tumorigenesis
-
Fujii, M. et al. A colorectal tumor organoid library demonstrates progressive loss of niche factor requirements during tumorigenesis. Cell Stem Cell 18, 827-838 (2016).
-
(2016)
Cell Stem Cell
, vol.18
, pp. 827-838
-
-
Fujii, M.1
-
26
-
-
84928974420
-
Prospective derivation of a living organoid biobank of colorectal cancer patients
-
van de Wetering, M. et al. Prospective derivation of a living organoid biobank of colorectal cancer patients. Cell 161, 933-945 (2015).
-
(2015)
Cell
, vol.161
, pp. 933-945
-
-
Van De Wetering, M.1
-
27
-
-
79961156560
-
Role of heterozygous apc mutation in niche succession and initiation of colorectal cancer-A computational study
-
Sasikumar, R., Rejitha, J.R., Binumon, P.K. & Manoj, M. Role of heterozygous APC mutation in niche succession and initiation of colorectal cancer-A computational study. PLoS One 6, e22720 (2011).
-
(2011)
PLoS One
, vol.6
, pp. e22720
-
-
Sasikumar, R.1
Rejitha, J.R.2
Binumon, P.K.3
Manoj, M.4
-
28
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
-
Takahashi, K. et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131, 861-872 (2007).
-
(2007)
Cell
, vol.131
, pp. 861-872
-
-
Takahashi, K.1
-
29
-
-
0032619765
-
Apc gene knockout mice as a model for familial adenomatous polyposis
-
Taketo, M.M. Apc gene knockout mice as a model for familial adenomatous polyposis. Prog. Exp. Tumor Res. 35, 109-119 (1999).
-
(1999)
Prog. Exp. Tumor Res
, vol.35
, pp. 109-119
-
-
Taketo, M.M.1
-
30
-
-
0033750994
-
Downregulation of cyclin d1 alters cdk 4-And cdk 2-specific phosphorylation of retinoblastoma protein
-
Yu, B., Lane, M.E., Pestell, R.G., Albanese, C. & Wadler, S. Downregulation of cyclin D1 alters cdk 4-And cdk 2-specific phosphorylation of retinoblastoma protein. Mol. Cell Biol. Res. Commun. 3, 352-359 (2000).
-
(2000)
Mol. Cell Biol. Res. Commun
, vol.3
, pp. 352-359
-
-
Yu, B.1
Lane, M.E.2
Pestell, R.G.3
Albanese, C.4
Wadler, S.5
-
31
-
-
84893363725
-
Wnt secretion is required to maintain high levels of wnt activity in colon cancer cells
-
Voloshanenko, O. et al. Wnt secretion is required to maintain high levels of Wnt activity in colon cancer cells. Nat. Commun. 4, 2610 (2013).
-
(2013)
Nat. Commun
, vol.4
, pp. 2610
-
-
Voloshanenko, O.1
-
32
-
-
34250344520
-
Colonic polyps in children and adolescents
-
Durno, C.A. Colonic polyps in children and adolescents. Can. J. Gastroenterol. 21, 233-239 (2007).
-
(2007)
Can. J. Gastroenterol
, vol.21
, pp. 233-239
-
-
Durno, C.A.1
-
33
-
-
84925491509
-
Mtorc1-mediated translational elongation limits intestinal tumour initiation and growth
-
Faller, W.J. et al. mTORC1-mediated translational elongation limits intestinal tumour initiation and growth. Nature 517, 497-500 (2015).
-
(2015)
Nature
, vol.517
, pp. 497-500
-
-
Faller, W.J.1
-
34
-
-
70349695861
-
Tankyrase inhibition stabilizes axin and antagonizes wnt signalling
-
Huang, S.M. et al. Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling. Nature 461, 614-620 (2009).
-
(2009)
Nature
, vol.461
, pp. 614-620
-
-
Huang, S.M.1
-
35
-
-
55949129367
-
Combination chemoprevention of intestinal carcinogenesis in a murine model of familial adenomatous polyposis
-
Ignatenko, N.A. et al. Combination chemoprevention of intestinal carcinogenesis in a murine model of familial adenomatous polyposis. Nutr. Cancer 60 (Suppl. 1), 30-35 (2008).
-
(2008)
Nutr. Cancer
, vol.60
, pp. 30-35
-
-
Ignatenko, N.A.1
-
36
-
-
80052333494
-
Readthrough of premature termination codons in the adenomatous polyposis coli gene restores its biological activity in human cancer cells
-
Floquet, C., Rousset, J.P. & Bidou, L. Readthrough of premature termination codons in the adenomatous polyposis coli gene restores its biological activity in human cancer cells. PLoS One 6, e24125 (2011).
-
(2011)
PLoS One
, vol.6
, pp. e24125
-
-
Floquet, C.1
Rousset, J.P.2
Bidou, L.3
-
37
-
-
77950837290
-
Restoration of apc gene function in colorectal cancer cells by aminoglycoside-And macrolide-induced read-through of premature termination codons
-
Zilberberg, A., Lahav, L. & Rosin-Arbesfeld, R. Restoration of APC gene function in colorectal cancer cells by aminoglycoside-And macrolide-induced read-through of premature termination codons. Gut 59, 496-507 (2010).
-
(2010)
Gut
, vol.59
, pp. 496-507
-
-
Zilberberg, A.1
Lahav, L.2
Rosin-Arbesfeld, R.3
-
38
-
-
84935032984
-
Apc restoration promotes cellular differentiation and establishes crypt homeostasis in colorectal cancer
-
Dow, L.E. et al. Apc restoration promotes cellular differentiation and establishes crypt homeostasis in colorectal cancer. Cell 161, 1539-1552 (2015).
-
(2015)
Cell
, vol.161
, pp. 1539-1552
-
-
Dow, L.E.1
-
39
-
-
84961113943
-
A resource of ribosomal RNA-depleted RNA-seq data from different normal adult and fetal human tissues
-
Choy, J.Y. et al. A resource of ribosomal RNA-depleted RNA-seq data from different normal adult and fetal human tissues. Sci. Data 2, 150063 (2015).
-
(2015)
Sci. Data
, vol.2
, pp. 150063
-
-
Choy, J.Y.1
-
40
-
-
84973164097
-
Genomic landscape of colorectal mucosa and adenomas
-
Borras, E. et al. Genomic landscape of colorectal mucosa and adenomas. Cancer Prev. Res. (Phila.) 9, 417-427 (2016).
-
(2016)
Cancer Prev. Res. (Phila
, vol.9
, pp. 417-427
-
-
Borras, E.1
-
41
-
-
84973124505
-
Gene signature in sessile serrated polyps identifies colon cancer subtype
-
Kanth, P. et al. Gene signature in sessile serrated polyps identifies colon cancer subtype. Cancer Prev. Res. (Phila.) 9, 456-465 (2016).
-
(2016)
Cancer Prev. Res. (Phila
, vol.9
, pp. 456-465
-
-
Kanth, P.1
-
42
-
-
84871809302
-
Star ultrafast universal RNA-seq aligner
-
Dobin, A. et al. STAR: ultrafast universal RNA-seq aligner. Bioinformatics 29, 15-21 (2013).
-
(2013)
Bioinformatics
, vol.29
, pp. 15-21
-
-
Dobin, A.1
-
43
-
-
62349130698
-
Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
-
Langmead, B., Trapnell, C., Pop, M. & Salzberg, S.L. Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol. 10, R25 (2009).
-
(2009)
Genome Biol
, vol.10
, pp. R25
-
-
Langmead, B.1
Trapnell, C.2
Pop, M.3
Salzberg, S.L.4
-
44
-
-
79961123152
-
Rsem accurate transcript quantification from RNA-seq data with or without a reference genome
-
Li, B. & Dewey, C.N. RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome. BMC Bioinformatics 12, 323 (2011).
-
(2011)
BMC Bioinformatics
, vol.12
, pp. 323
-
-
Li, B.1
Dewey, C.N.2
-
45
-
-
0015311728
-
Species identity of insect cell lines
-
Greene, A.E., Charney, J., Nichols, W.W. & Coriell, L.L. Species identity of insect cell lines. In Vitro 7, 313-322 (1972).
-
(1972)
In Vitro
, vol.7
, pp. 313-322
-
-
Greene, A.E.1
Charney, J.2
Nichols, W.W.3
Coriell, L.L.4
|