-
2
-
-
79751489596
-
Molecular genetics of colorectal cancer
-
Fearon ER.Molecular genetics of colorectal cancer. Annu Rev Pathol 2011;6:479-507.
-
(2011)
Annu Rev Pathol
, vol.6
, pp. 479-507
-
-
Fearon, E.R.1
-
3
-
-
79959715791
-
Adenoma detection rate increases with each decade of life after 50 years of age
-
Diamond SJ, Enestvedt BK, Jiang Z, Holub JL, Gupta M, Lieberman DA, et al. Adenoma detection rate increases with each decade of life after 50 years of age. Gastrointest Endosc 2011;74:135-40.
-
(2011)
Gastrointest Endosc
, vol.74
, pp. 135-140
-
-
Diamond, S.J.1
Enestvedt, B.K.2
Jiang, Z.3
Holub, J.L.4
Gupta, M.5
Lieberman, D.A.6
-
4
-
-
0032521433
-
Mutational analysis of the APC/beta-catenin/Tcf pathway in colorectal cancer
-
Sparks AB, Morin PJ, Vogelstein B, Kinzler KW.Mutational analysis of the APC/beta-catenin/Tcf pathway in colorectal cancer. Cancer Res 1998;58:1130-4.
-
(1998)
Cancer Res
, vol.58
, pp. 1130-1134
-
-
Sparks, A.B.1
Morin, P.J.2
Vogelstein, B.3
Kinzler, K.W.4
-
7
-
-
84863922124
-
Comprehensive molecular characterization of human colon and rectal cancer
-
The Cancer Genome Atlas Network
-
The Cancer Genome Atlas Network. Comprehensive molecular characterization of human colon and rectal cancer. Nature 2012;487:330-7.
-
(2012)
Nature
, vol.487
, pp. 330-337
-
-
-
8
-
-
36248962105
-
The genomic landscapes of human breast and colorectal cancers
-
Wood LD, Parsons DW, Jones S, Lin J, Sjoblom T, Leary RJ, et al. The genomic landscapes of human breast and colorectal cancers. Science 2007;318:1108-13.
-
(2007)
Science
, vol.318
, pp. 1108-1113
-
-
Wood, L.D.1
Parsons, D.W.2
Jones, S.3
Lin, J.4
Sjoblom, T.5
Leary, R.J.6
-
9
-
-
84873441292
-
Half or more of the somatic mutations in cancers of self-renewing tissues originate prior to tumor initiation
-
Tomasetti C, Vogelstein B, Parmigiani G. Half or more of the somatic mutations in cancers of self-renewing tissues originate prior to tumor initiation. Proc Natl Acad Sci U S A 2013;110:1999-2004.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 1999-2004
-
-
Tomasetti, C.1
Vogelstein, B.2
Parmigiani, G.3
-
10
-
-
84871944090
-
Haplotype-based profiling of subtle allelic imbalance with SNP arrays
-
Vattathil S, Scheet P. Haplotype-based profiling of subtle allelic imbalance with SNP arrays. Genome Res 2013;23:152-8.
-
(2013)
Genome Res
, vol.23
, pp. 152-158
-
-
Vattathil, S.1
Scheet, P.2
-
11
-
-
84865459654
-
Recurrent R-spondin fusions in colon cancer
-
Seshagiri S, Stawiski EW, Durinck S, Modrusan Z, Storm EE, Conboy CB, et al. Recurrent R-spondin fusions in colon cancer. Nature 2012;488: 660-4.
-
(2012)
Nature
, vol.488
, pp. 660-664
-
-
Seshagiri, S.1
Stawiski, E.W.2
Durinck, S.3
Modrusan, Z.4
Storm, E.E.5
Conboy, C.B.6
-
12
-
-
84864436663
-
A comprehensive characterization of genome-wide copy number aberrations in colorectal cancer reveals novel oncogenes and patterns of alterations
-
Xie T, G DA, Lamb JR, Martin E, Wang K, Tejpar S, et al. A comprehensive characterization of genome-wide copy number aberrations in colorectal cancer reveals novel oncogenes and patterns of alterations. PLoS One 2012;7:e42001.
-
(2012)
PLoS One
, vol.7
, pp. e42001
-
-
Xie, T.1
Lamb, J.R.2
Martin, E.3
Wang, K.4
Tejpar, S.5
-
13
-
-
0038005018
-
DAVID: Database for annotation, visualization, and integrated discovery
-
Dennis GJr., Sherman BT, Hosack DA, Yang J, Gao W, Lane HC, et al. DAVID: database for annotation, visualization, and integrated discovery. Genome Biol 2003;4:P3.
-
(2003)
Genome Biol
, vol.4
, pp. 3
-
-
Dennis, G.1
Sherman, B.T.2
Hosack, D.A.3
Yang, J.4
Gao, W.5
Lane, H.C.6
-
14
-
-
84860782006
-
Absolute quantification of somatic DNA alterations in human cancer
-
Carter SL, Cibulskis K, Helman E, McKenna A, Shen H, Zack T, et al. Absolute quantification of somatic DNA alterations in human cancer. Nat Biotechnol 2012;30:413-21.
-
(2012)
Nat Biotechnol
, vol.30
, pp. 413-421
-
-
Carter, S.L.1
Cibulskis, K.2
Helman, E.3
McKenna, A.4
Shen, H.5
Zack, T.6
-
15
-
-
84880507665
-
Mutational heterogeneity in cancer and the search for new cancerassociated genes
-
Lawrence MS, Stojanov P, Polak P, Kryukov GV, Cibulskis K, Sivachenko A, et al. Mutational heterogeneity in cancer and the search for new cancerassociated genes. Nature 2013;499:214-8.
-
(2013)
Nature
, vol.499
, pp. 214-218
-
-
Lawrence, M.S.1
Stojanov, P.2
Polak, P.3
Kryukov, G.V.4
Cibulskis, K.5
Sivachenko, A.6
-
16
-
-
84882837534
-
Signatures of mutational processes in human cancer
-
Alexandrov LB, Nik-Zainal S, Wedge DC, Aparicio SA, Behjati S, Biankin AV, et al. Signatures of mutational processes in human cancer. Nature 2013; 500:415-21. 17.
-
(2013)
Nature
, vol.500
, Issue.17
, pp. 415-421
-
-
Alexandrov, L.B.1
Nik-Zainal, S.2
Wedge, D.C.3
Aparicio, S.A.4
Behjati, S.5
Biankin, A.V.6
-
17
-
-
78249261016
-
Accumulation of driver and passenger mutations during tumor progression
-
Bozic I, Antal T, Ohtsuki H, Carter H, Kim D, Chen S, et al. Accumulation of driver and passenger mutations during tumor progression. Proc Natl Acad Sci U S A 2010;107:18545-50.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 18545-18550
-
-
Bozic, I.1
Antal, T.2
Ohtsuki, H.3
Carter, H.4
Kim, D.5
Chen, S.6
-
18
-
-
84873084751
-
Exome sequencing identifies mutation in CNOT3 and ribosomal genes RPL5 and RPL10 in T-cell acute lymphoblastic leukemia
-
De Keersmaecker K, Atak ZK, Li N, Vicente C, Patchett S, Girardi T, et al. Exome sequencing identifies mutation in CNOT3 and ribosomal genes RPL5 and RPL10 in T-cell acute lymphoblastic leukemia. Nat Genet 2013;45:186-90.
-
(2013)
Nat Genet
, vol.45
, pp. 186-190
-
-
De Keersmaecker, K.1
Atak, Z.K.2
Li, N.3
Vicente, C.4
Patchett, S.5
Girardi, T.6
-
19
-
-
84875740314
-
Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal
-
Gao J, Aksoy BA, Dogrusoz U, Dresdner G, Gross B, Sumer SO, et al. Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal. Sci Signal 2013;6:pl1.
-
(2013)
Sci Signal
, vol.6
, pp. l1
-
-
Gao, J.1
Aksoy, B.A.2
Dogrusoz, U.3
Dresdner, G.4
Gross, B.5
Sumer, S.O.6
-
20
-
-
73349110071
-
Exome sequencing identifies the cause of a mendelian disorder
-
Ng SB, Buckingham KJ, Lee C, Bigham AW, Tabor HK, Dent KM, et al. Exome sequencing identifies the cause of a mendelian disorder. Nat Genet 2010;42:30-5.
-
(2010)
Nat Genet
, vol.42
, pp. 30-35
-
-
Ng, S.B.1
Buckingham, K.J.2
Lee, C.3
Bigham, A.W.4
Tabor, H.K.5
Dent, K.M.6
-
21
-
-
84857997501
-
A new whole genome amplification method for studying clonal evolution patterns in malignant colorectal polyps
-
Hirsch D, Camps J, Varma S, Kemmerling R, Stapleton M, Ried T, et al. A new whole genome amplification method for studying clonal evolution patterns in malignant colorectal polyps. Genes Chromosomes Cancer 2012;51:490-500.
-
(2012)
Genes Chromosomes Cancer
, vol.51
, pp. 490-500
-
-
Hirsch, D.1
Camps, J.2
Varma, S.3
Kemmerling, R.4
Stapleton, M.5
Ried, T.6
-
22
-
-
58249089865
-
Multiple putative oncogenes at the chromosome 20q amplicon contribute to colorectal adenoma to carcinoma progression
-
Carvalho B, Postma C, Mongera S, Hopmans E, Diskin S, van De Wiel MA, et al. Multiple putative oncogenes at the chromosome 20q amplicon contribute to colorectal adenoma to carcinoma progression. Gut 2009;58:79-89.
-
(2009)
Gut
, vol.58
, pp. 79-89
-
-
Carvalho, B.1
Postma, C.2
Mongera, S.3
Hopmans, E.4
Diskin, S.5
Van De Wiel, M.A.6
-
23
-
-
84973136770
-
Demographic, tumor characteristics, and outcomes associated with SMAD4 mutation in colorectal cancer
-
abstr 565
-
Mehrvarz Sarshekeh A, Overman MJ, Kee BK, Fogelman DR, Dasari A, Raghav KPS, et al. Demographic, tumor characteristics, and outcomes associated with SMAD4 mutation in colorectal cancer. J Clin Oncol 34, 2016(suppl 4S; abstr 565).
-
(2016)
J Clin Oncol
, vol.34
-
-
Mehrvarz, S.A.1
Overman, M.J.2
Kee, B.K.3
Fogelman, D.R.4
Dasari, A.5
Raghav, K.P.S.6
-
24
-
-
0141842696
-
Common genetic evolutionary pathways in familial adenomatous polyposis tumors
-
Tarafa G, Prat E, Risques RA, Gonzalez S, Camps J, Grau M, et al. Common genetic evolutionary pathways in familial adenomatous polyposis tumors. Cancer Res 2003;63:5731-7.
-
(2003)
Cancer Res
, vol.63
, pp. 5731-5737
-
-
Tarafa, G.1
Prat, E.2
Risques, R.A.3
Gonzalez, S.4
Camps, J.5
Grau, M.6
-
25
-
-
0037096906
-
The just-right' signaling model: APC somatic mutations are selected based on a specific level of activation of the beta-catenin signaling cascade
-
Albuquerque C, Breukel C, van Der Luijt R, Fidalgo P, Lage P, Slors FJ, et al. The just-right' signaling model: APC somatic mutations are selected based on a specific level of activation of the beta-catenin signaling cascade. Hum Mol Genet 2002;11:1549-60.
-
(2002)
Hum Mol Genet
, vol.11
, pp. 1549-1560
-
-
Albuquerque, C.1
Breukel, C.2
Van Der Luijt, R.3
Fidalgo, P.4
Lage, P.5
Slors, F.J.6
-
26
-
-
45749140081
-
Functional definition of the mutation cluster region of adenomatous polyposis coli in colorectal tumours
-
Kohler EM, Derungs A, Daum G, Behrens J, Schneikert J. Functional definition of the mutation cluster region of adenomatous polyposis coli in colorectal tumours. Hum Mol Genet 2008;17:1978-87.
-
(2008)
Hum Mol Genet
, vol.17
, pp. 1978-1987
-
-
Kohler, E.M.1
Derungs, A.2
Daum, G.3
Behrens, J.4
Schneikert, J.5
-
27
-
-
0032823133
-
The type of somatic mutation at apc in familial adenomatous polyposis is determined by the site of the germline mutation: A new facet to knudson's two-hit' hypothesis
-
Lamlum H, Ilyas M, Rowan A, Clark S, Johnson V, Bell J, et al. the type of somatic mutation at apc in familial adenomatous polyposis is determined by the site of the germline mutation: A new facet to knudson's two-hit' hypothesis. Nat Med 1999;5:1071-5.
-
(1999)
Nat Med
, vol.5
, pp. 1071-1075
-
-
Lamlum, H.1
Ilyas, M.2
Rowan, A.3
Clark, S.4
Johnson, V.5
Bell, J.6
-
28
-
-
84903767326
-
Can we safely target the WNT pathway?
-
Kahn M. Can we safely target the WNT pathway? Nat Rev Drug Discov 2014;13:513-32.
-
(2014)
Nat Rev Drug Discov
, vol.13
, pp. 513-532
-
-
Kahn, M.1
-
29
-
-
67651159312
-
Stem cells, self-renewal, and differentiation in the intestinal epithelium
-
van Der Flier LG, Clevers H. Stem cells, self-renewal, and differentiation in the intestinal epithelium. Annu Rev Physiol 2009;71:241-60.
-
(2009)
Annu Rev Physiol
, vol.71
, pp. 241-260
-
-
Van Der Flier, L.G.1
Clevers, H.2
-
30
-
-
84923952286
-
A Big Bang model of human colorectal tumor growth
-
Sottoriva A, Kang H, Ma Z, Graham TA, Salomon MP, Zhao J, et al. A Big Bang model of human colorectal tumor growth. Nat Genet 2015;47: 209-16.
-
(2015)
Nat Genet
, vol.47
, pp. 209-216
-
-
Sottoriva, A.1
Kang, H.2
Ma, Z.3
Graham, T.A.4
Salomon, M.P.5
Zhao, J.6
-
31
-
-
84873275400
-
Possible involvement of Wnt11 in colorectal cancer progression
-
Nishioka M, Ueno K, Hazama S, Okada T, Sakai K, Suehiro Y, et al. Possible involvement of Wnt11 in colorectal cancer progression. Mol Carcinog 2013;52:207-17.
-
(2013)
Mol Carcinog
, vol.52
, pp. 207-217
-
-
Nishioka, M.1
Ueno, K.2
Hazama, S.3
Okada, T.4
Sakai, K.5
Suehiro, Y.6
-
32
-
-
84901011543
-
Exome sequencing reveals frequent inactivating mutations in ARID1A, ARID1B, ARID2 and ARID4A inmicrosatellite unstable colorectal cancer
-
Cajuso T, Hanninen UA, Kondelin J, Gylfe AE, Tanskanen T, Katainen R, et al. Exome sequencing reveals frequent inactivating mutations in ARID1A, ARID1B, ARID2 and ARID4A inmicrosatellite unstable colorectal cancer. Int J Cancer 2014;135:611-23.
-
(2014)
Int J Cancer
, vol.135
, pp. 611-623
-
-
Cajuso, T.1
Hanninen, U.A.2
Kondelin, J.3
Gylfe, A.E.4
Tanskanen, T.5
Katainen, R.6
-
33
-
-
0034102422
-
APC mutations are sufficient for the growth of early colorectal adenomas
-
Lamlum H, Papadopoulou A, Ilyas M, Rowan A, Gillet C, Hanby A, et al. APC mutations are sufficient for the growth of early colorectal adenomas. Proc Natl Acad Sci U S A 2000;97:2225-8.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 2225-2228
-
-
Lamlum, H.1
Papadopoulou, A.2
Ilyas, M.3
Rowan, A.4
Gillet, C.5
Hanby, A.6
|