메뉴 건너뛰기




Volumn 35, Issue , 1999, Pages 109-119

Apc gene knockout mice as a model for familial adenomatous polyposis

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; COLON POLYPOSIS; DISEASE MODEL; GENETICS; MOUSE; MOUSE MUTANT; REVIEW; TUMOR SUPPRESSOR GENE;

EID: 0032619765     PISSN: 00796263     EISSN: None     Source Type: Book Series    
DOI: 10.1159/000062007     Document Type: Article
Times cited : (7)

References (44)
  • 10
    • 0027769633 scopus 로고
    • Restriction of ocular fundus lesions to a specific subgroup of APC mutations in adenomatous polyposis coli patients
    • Olschwang S, Tiret A, Laurent-Puig P, Muleris M, Parc R, Thomas G: Restriction of ocular fundus lesions to a specific subgroup of APC mutations in adenomatous polyposis coli patients. Cell 1993;75:959-968.
    • (1993) Cell , vol.75 , pp. 959-968
    • Olschwang, S.1    Tiret, A.2    Laurent-Puig, P.3    Muleris, M.4    Parc, R.5    Thomas, G.6
  • 11
    • 0027378766 scopus 로고
    • APC gene messenger RNA: Novel isoforms that lack exon 7
    • Oshima M, Sugiyama H, Kitagawa K, Taketo M: APC gene messenger RNA: Novel isoforms that lack exon 7. Cancer Res 1993;53:5589-5591.
    • (1993) Cancer Res , vol.53 , pp. 5589-5591
    • Oshima, M.1    Sugiyama, H.2    Kitagawa, K.3    Taketo, M.4
  • 12
    • 0028229809 scopus 로고
    • Demonstration of promoter activity and alternative splicing in the region 5′ to exon 1 of the APC gene
    • Thliveris A, Samowitz W, Matunami N, Groden J, White R: Demonstration of promoter activity and alternative splicing in the region 5′ to exon 1 of the APC gene. Cancer Res 1994;54:2991-2995.
    • (1994) Cancer Res , vol.54 , pp. 2991-2995
    • Thliveris, A.1    Samowitz, W.2    Matunami, N.3    Groden, J.4    White, R.5
  • 13
  • 15
    • 0027930066 scopus 로고
    • The APC gene product associates with microtubules in vivo and promotes their assembly in vitro
    • Munemitsu S, Souza B, Müller O, Albert I, Rubinfeld B, Polakis P: The APC gene product associates with microtubules in vivo and promotes their assembly in vitro. Cancer Res 1994;54:3676-3681.
    • (1994) Cancer Res , vol.54 , pp. 3676-3681
    • Munemitsu, S.1    Souza, B.2    Müller, O.3    Albert, I.4    Rubinfeld, B.5    Polakis, P.6
  • 17
    • 0027756014 scopus 로고
    • Association of the APC tumor suppressor protein with catenins
    • Su L-K, Vogelstein B, Kinzler KW: Association of the APC tumor suppressor protein with catenins. Science 1993;262:1734-1737.
    • (1993) Science , vol.262 , pp. 1734-1737
    • Su, L.-K.1    Vogelstein, B.2    Kinzler, K.W.3
  • 18
    • 0029982877 scopus 로고    scopus 로고
    • The adenomatous polyposis coli tumor suppressor protein localizes to plasma membrane sites involved in active cell migration
    • Nathke IS, Adams CL, Polakis P, Sellin JH, Nelson WJ: The adenomatous polyposis coli tumor suppressor protein localizes to plasma membrane sites involved in active cell migration. J Cell Biol 1996;134:165-178.
    • (1996) J Cell Biol , vol.134 , pp. 165-178
    • Nathke, I.S.1    Adams, C.L.2    Polakis, P.3    Sellin, J.H.4    Nelson, W.J.5
  • 19
    • 0030987826 scopus 로고    scopus 로고
    • Nuclear and cytoplasmic localization of the adenomatous polyposis coli protein
    • Neufeld KL, White RL: Nuclear and cytoplasmic localization of the adenomatous polyposis coli protein. Proc Natl Acad Sci USA 1997;94:3034-3039.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 3034-3039
    • Neufeld, K.L.1    White, R.L.2
  • 22
    • 0029047954 scopus 로고
    • Loss of Ape heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncation Ape gene
    • Oshima M, Oshima H, Kitagawa K, Kobayashi M, Itakura C, Taketo M: Loss of Ape heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncation Ape gene. Proc Natl Acad Sci USA 1995;92:4482-4486.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 4482-4486
    • Oshima, M.1    Oshima, H.2    Kitagawa, K.3    Kobayashi, M.4    Itakura, C.5    Taketo, M.6
  • 25
    • 0029069971 scopus 로고
    • Evidence against dominant negative mechanisms of intestinal polyp formation by Ape gene mutations
    • Oshima M, Oshima H, Kobayashi M, Tsutsumi M, Taketo MM: Evidence against dominant negative mechanisms of intestinal polyp formation by Ape gene mutations. Cancer Res 1995;55:2719-2722.
    • (1995) Cancer Res , vol.55 , pp. 2719-2722
    • Oshima, M.1    Oshima, H.2    Kobayashi, M.3    Tsutsumi, M.4    Taketo, M.M.5
  • 26
    • 0028864589 scopus 로고
    • Multiple APC messenger RNA isoforms encoding exon 15 short open reading frames are expressed in the context of a novel exon 10A-derived sequence
    • Sulekova Z, Reina-Sanchez J, Ballhausen WG: Multiple APC messenger RNA isoforms encoding exon 15 short open reading frames are expressed in the context of a novel exon 10A-derived sequence. Int J Cancer 1995;63:435-441.
    • (1995) Int J Cancer , vol.63 , pp. 435-441
    • Sulekova, Z.1    Reina-Sanchez, J.2    Ballhausen, W.G.3
  • 29
    • 0015237292 scopus 로고
    • Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs
    • Vane JR: Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nat New Biol 1971;231:232-235.
    • (1971) Nat New Biol , vol.231 , pp. 232-235
    • Vane, J.R.1
  • 30
    • 0028044609 scopus 로고
    • Towards a better aspirin
    • Vane J: Towards a better aspirin. Nature 1994;367:215-216.
    • (1994) Nature , vol.367 , pp. 215-216
    • Vane, J.1
  • 31
    • 0027293391 scopus 로고
    • Expression of mRNA for cyclooxygenase-1 and cyclooxygenase-2 in human tissues
    • O'Neill GP, Ford-Hutchinson AW: Expression of mRNA for cyclooxygenase-1 and cyclooxygenase-2 in human tissues. FEBS Lett 1993;330:156-160.
    • (1993) FEBS Lett , vol.330 , pp. 156-160
    • O'Neill, G.P.1    Ford-Hutchinson, A.W.2
  • 32
    • 0025365504 scopus 로고
    • Cyclooxygenase is an immediate-early gene induced by interleukin-1 in human endothelial cells
    • Maier JAM, Hla T, Maciag H: Cyclooxygenase is an immediate-early gene induced by interleukin-1 in human endothelial cells. J Biol Chem 1990;265:10805-10808.
    • (1990) J Biol Chem , vol.265 , pp. 10805-10808
    • Maier, J.A.M.1    Hla, T.2    Maciag, H.3
  • 33
    • 0027076645 scopus 로고
    • Selective expression of mitogen-inducible cyclooxygenase in macrophages stimulated with lipopolysaccharide
    • Lee SH, Soyoola E, Chanmugam P, Hart S, Sun W, Zhong H, Liou S, Simmons D, Hwang D: Selective expression of mitogen-inducible cyclooxygenase in macrophages stimulated with lipopolysaccharide. J Biol Chem 1992;267:25934-25938.
    • (1992) J Biol Chem , vol.267 , pp. 25934-25938
    • Lee, S.H.1    Soyoola, E.2    Chanmugam, P.3    Hart, S.4    Sun, W.5    Zhong, H.6    Liou, S.7    Simmons, D.8    Hwang, D.9
  • 34
    • 0026735231 scopus 로고
    • CDNA cloning and functional activity of a glucocorticoid-regulated inflammatory cyclooxygenase
    • O'Banion MK, Winn VD, Young DA: cDNA cloning and functional activity of a glucocorticoid-regulated inflammatory cyclooxygenase. Proc Natl Acad Sci USA 1992;89:4888-4892.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 4888-4892
    • O'Banion, M.K.1    Winn, V.D.2    Young, D.A.3
  • 35
    • 0026588961 scopus 로고
    • Mitogen-inducible prostaglandin G/H synthase: A new target for nonsteroidal antiinflammatory drugs
    • Xie W, Robertson DL, Simmons DL: Mitogen-inducible prostaglandin G/H synthase: A new target for nonsteroidal antiinflammatory drugs. Drug Dev Res 1992;25:249-265.
    • (1992) Drug Dev Res , vol.25 , pp. 249-265
    • Xie, W.1    Robertson, D.L.2    Simmons, D.L.3
  • 36
    • 0027146692 scopus 로고
    • Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase
    • Mitchell JA, Akarasereenont P, Thiemermann C, Flower RJ, Vane JR: Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase. Proc Natl Acad Sci USA 1993;90:11693-11697.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 11693-11697
    • Mitchell, J.A.1    Akarasereenont, P.2    Thiemermann, C.3    Flower, R.J.4    Vane, J.R.5
  • 37
    • 0026761738 scopus 로고
    • Aspirin and the potential role of prostaglandin in colon cancer
    • Marnett LJ: Aspirin and the potential role of prostaglandin in colon cancer. Cancer Res 1992;52:5575-5589.
    • (1992) Cancer Res , vol.52 , pp. 5575-5589
    • Marnett, L.J.1
  • 43
    • 0000147542 scopus 로고    scopus 로고
    • Recent advances in chemoprevention of cancer
    • Hong WK, Sporn MB: Recent advances in chemoprevention of cancer. Science 1997;278:1073-1077.
    • (1997) Science , vol.278 , pp. 1073-1077
    • Hong, W.K.1    Sporn, M.B.2
  • 44
    • 54249102643 scopus 로고    scopus 로고
    • Self promotion? Intimate connections between the tumor suppressor APC and prostaglandin H synthase-2 (COX-2)
    • Prescott SM, White RL: Self promotion? Intimate connections between the tumor suppressor APC and prostaglandin H synthase-2 (COX-2). Cell 1996;87:801-803.
    • (1996) Cell , vol.87 , pp. 801-803
    • Prescott, S.M.1    White, R.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.