메뉴 건너뛰기




Volumn 6, Issue 8, 2011, Pages

Readthrough of premature termination codons in the adenomatous polyposis coli gene restores its biological activity in human cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; APC PROTEIN; BETA CATENIN; GENTAMICIN; NEGAMYCIN; T CELL FACTOR PROTEIN; AMINOGLYCOSIDE; ANTIINFECTIVE AGENT; COMPLEMENTARY DNA;

EID: 80052333494     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0024125     Document Type: Article
Times cited : (43)

References (33)
  • 1
    • 35648988947 scopus 로고    scopus 로고
    • Adenomatous polyposis coli (APC): a multi-functional tumor suppressor gene
    • Aoki K, Taketo MM, (2007) Adenomatous polyposis coli (APC): a multi-functional tumor suppressor gene. J Cell Sci 120: 3327-3335.
    • (2007) J Cell Sci , vol.120 , pp. 3327-3335
    • Aoki, K.1    Taketo, M.M.2
  • 2
    • 0036953625 scopus 로고    scopus 로고
    • Wnt/beta-catenin/tcf signaling: a critical pathway in gastrointestinal tumorigenesis
    • Kolligs FT, Bommer G, Goke B, (2002) Wnt/beta-catenin/tcf signaling: a critical pathway in gastrointestinal tumorigenesis. Digestion 66: 131-144.
    • (2002) Digestion , vol.66 , pp. 131-144
    • Kolligs, F.T.1    Bommer, G.2    Goke, B.3
  • 3
    • 0028941969 scopus 로고
    • Response of colon cancer cell lines to the introduction of APC, a colon-specific tumor suppressor gene
    • Groden J, Joslyn G, Samowitz W, Jones D, Bhattacharyya N, et al. (1995) Response of colon cancer cell lines to the introduction of APC, a colon-specific tumor suppressor gene. Cancer Res 55: 1531-1539.
    • (1995) Cancer Res , vol.55 , pp. 1531-1539
    • Groden, J.1    Joslyn, G.2    Samowitz, W.3    Jones, D.4    Bhattacharyya, N.5
  • 5
    • 2642698862 scopus 로고    scopus 로고
    • APC gene: database of germline and somatic mutations in human tumors and cell lines
    • Laurent-Puig P, Beroud C, Soussi T, (1998) APC gene: database of germline and somatic mutations in human tumors and cell lines. Nucleic Acids Res 26: 269-270.
    • (1998) Nucleic Acids Res , vol.26 , pp. 269-270
    • Laurent-Puig, P.1    Beroud, C.2    Soussi, T.3
  • 6
    • 33845996905 scopus 로고    scopus 로고
    • Aminoglycoside-induced translational read-through in disease: overcoming nonsense mutations by pharmacogenetic therapy
    • Zingman LV, Park S, Olson TM, Alekseev AE, Terzic A, (2007) Aminoglycoside-induced translational read-through in disease: overcoming nonsense mutations by pharmacogenetic therapy. Clin Pharmacol Ther 81: 99-103.
    • (2007) Clin Pharmacol Ther , vol.81 , pp. 99-103
    • Zingman, L.V.1    Park, S.2    Olson, T.M.3    Alekseev, A.E.4    Terzic, A.5
  • 7
    • 54849413018 scopus 로고    scopus 로고
    • Introducing sense into nonsense in treatments of human genetic diseases
    • Linde L, Kerem B, (2008) Introducing sense into nonsense in treatments of human genetic diseases. Trends Genet 24: 552-563.
    • (2008) Trends Genet , vol.24 , pp. 552-563
    • Linde, L.1    Kerem, B.2
  • 8
    • 68649089108 scopus 로고    scopus 로고
    • Pharmaceuticals targeting nonsense mutations in genetic diseases: progress in development
    • Rowe SM, Clancy JP, (2009) Pharmaceuticals targeting nonsense mutations in genetic diseases: progress in development. BioDrugs 23: 165-174.
    • (2009) BioDrugs , vol.23 , pp. 165-174
    • Rowe, S.M.1    Clancy, J.P.2
  • 9
    • 0347993773 scopus 로고    scopus 로고
    • Negamycin restores dystrophin expression in skeletal and cardiac muscles of mdx mice
    • Arakawa M, Shiozuka M, Nakayama Y, Hara T, Hamada M, et al. (2003) Negamycin restores dystrophin expression in skeletal and cardiac muscles of mdx mice. J Biochem 134: 751-758.
    • (2003) J Biochem , vol.134 , pp. 751-758
    • Arakawa, M.1    Shiozuka, M.2    Nakayama, Y.3    Hara, T.4    Hamada, M.5
  • 10
    • 39449127401 scopus 로고    scopus 로고
    • Drug-induced readthrough of premature stop codons leads to the stabilization of laminin alpha2 chain mRNA in CMD myotubes
    • Allamand V, Bidou L, Arakawa M, Floquet C, Shiozuka M, et al. (2008) Drug-induced readthrough of premature stop codons leads to the stabilization of laminin alpha2 chain mRNA in CMD myotubes. J Gene Med 10: 217-224.
    • (2008) J Gene Med , vol.10 , pp. 217-224
    • Allamand, V.1    Bidou, L.2    Arakawa, M.3    Floquet, C.4    Shiozuka, M.5
  • 12
    • 77950837290 scopus 로고    scopus 로고
    • Restoration of APC gene function in colorectal cancer cells by aminoglycoside- and macrolide-induced read-through of premature termination codons
    • Zilberberg A, Lahav L, Rosin-Arbesfeld R, (2010) Restoration of APC gene function in colorectal cancer cells by aminoglycoside- and macrolide-induced read-through of premature termination codons. Gut 59: 496-507.
    • (2010) Gut , vol.59 , pp. 496-507
    • Zilberberg, A.1    Lahav, L.2    Rosin-Arbesfeld, R.3
  • 13
    • 1842586020 scopus 로고    scopus 로고
    • Premature stop codons involved in muscular dystrophies show a broad spectrum of readthrough efficiencies in response to gentamicin treatment
    • Bidou L, Hatin I, Perez N, Allamand V, Panthier JJ, et al. (2004) Premature stop codons involved in muscular dystrophies show a broad spectrum of readthrough efficiencies in response to gentamicin treatment. Gene Ther 11: 619-627.
    • (2004) Gene Ther , vol.11 , pp. 619-627
    • Bidou, L.1    Hatin, I.2    Perez, N.3    Allamand, V.4    Panthier, J.J.5
  • 14
    • 0033854425 scopus 로고    scopus 로고
    • Sequence specificity of aminoglycoside-induced stop condon readthrough: potential implications for treatment of Duchenne muscular dystrophy
    • Howard MT, Shirts BH, Petros LM, Flanigan KM, Gesteland RF, et al. (2000) Sequence specificity of aminoglycoside-induced stop condon readthrough: potential implications for treatment of Duchenne muscular dystrophy. Ann Neurol 48: 164-169.
    • (2000) Ann Neurol , vol.48 , pp. 164-169
    • Howard, M.T.1    Shirts, B.H.2    Petros, L.M.3    Flanigan, K.M.4    Gesteland, R.F.5
  • 15
    • 33747502470 scopus 로고    scopus 로고
    • Readthrough strategies for stop codons in Duchenne muscular dystrophy
    • Aurino S, Nigro V, (2006) Readthrough strategies for stop codons in Duchenne muscular dystrophy. Acta Myol 25: 5-12.
    • (2006) Acta Myol , vol.25 , pp. 5-12
    • Aurino, S.1    Nigro, V.2
  • 16
    • 34247200483 scopus 로고    scopus 로고
    • In vitro prediction of stop-codon suppression by intravenous gentamicin in patients with cystic fibrosis: a pilot study
    • Sermet-Gaudelus I, Renouil M, Fajac A, Bidou L, Parbaille B, et al. (2007) In vitro prediction of stop-codon suppression by intravenous gentamicin in patients with cystic fibrosis: a pilot study. BMC Med 5: 5.
    • (2007) BMC Med , vol.5 , pp. 5
    • Sermet-Gaudelus, I.1    Renouil, M.2    Fajac, A.3    Bidou, L.4    Parbaille, B.5
  • 18
    • 0033929810 scopus 로고    scopus 로고
    • Aminoglycoside antibiotics mediate context-dependent suppression of termination codons in a mammalian translation system
    • Manuvakhova M, Keeling K, Bedwell DM, (2000) Aminoglycoside antibiotics mediate context-dependent suppression of termination codons in a mammalian translation system. RNA 6: 1044-1055.
    • (2000) RNA , vol.6 , pp. 1044-1055
    • Manuvakhova, M.1    Keeling, K.2    Bedwell, D.M.3
  • 19
    • 0001828219 scopus 로고    scopus 로고
    • UAG readthrough in mammalian cells: effect of upstream and downstream stop codon contexts reveal different signals
    • Cassan M, Rousset JP, (2001) UAG readthrough in mammalian cells: effect of upstream and downstream stop codon contexts reveal different signals. BMC Mol Biol 2: 3.
    • (2001) BMC Mol Biol , vol.2 , pp. 3
    • Cassan, M.1    Rousset, J.P.2
  • 20
    • 1442353747 scopus 로고    scopus 로고
    • Readthrough of dystrophin stop codon mutations induced by aminoglycosides
    • Howard MT, Anderson CB, Fass U, Khatri S, Gesteland RF, et al. (2004) Readthrough of dystrophin stop codon mutations induced by aminoglycosides. Ann Neurol 55: 422-426.
    • (2004) Ann Neurol , vol.55 , pp. 422-426
    • Howard, M.T.1    Anderson, C.B.2    Fass, U.3    Khatri, S.4    Gesteland, R.F.5
  • 21
    • 0022423513 scopus 로고
    • Suppression of a nonsense mutation in mammalian cells in vivo by the aminoglycoside antibiotics G-418 and paromomycin
    • Burke JF, Mogg AE, (1985) Suppression of a nonsense mutation in mammalian cells in vivo by the aminoglycoside antibiotics G-418 and paromomycin. Nucleic Acids Res 13: 6265-6272.
    • (1985) Nucleic Acids Res , vol.13 , pp. 6265-6272
    • Burke, J.F.1    Mogg, A.E.2
  • 22
    • 34848900487 scopus 로고    scopus 로고
    • A mouse model for nonsense mutation bypass therapy shows a dramatic multiday response to geneticin
    • Yang C, Feng J, Song W, Wang J, Tsai B, et al. (2007) A mouse model for nonsense mutation bypass therapy shows a dramatic multiday response to geneticin. Proc Natl Acad Sci U S A 104: 15394-15399.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 15394-15399
    • Yang, C.1    Feng, J.2    Song, W.3    Wang, J.4    Tsai, B.5
  • 23
    • 0030949463 scopus 로고    scopus 로고
    • Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
    • Morin PJ, Sparks AB, Korinek V, Barker N, Clevers H, et al. (1997) Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Science 275: 1787-1790.
    • (1997) Science , vol.275 , pp. 1787-1790
    • Morin, P.J.1    Sparks, A.B.2    Korinek, V.3    Barker, N.4    Clevers, H.5
  • 24
    • 0028242356 scopus 로고
    • Premature translation termination mutations are efficiently suppressed in a highly conserved region of yeast Ste6p, a member of the ATP-binding cassette (ABC) transporter family
    • Fearon K, McClendon V, Bonetti B, Bedwell DM, (1994) Premature translation termination mutations are efficiently suppressed in a highly conserved region of yeast Ste6p, a member of the ATP-binding cassette (ABC) transporter family. J Biol Chem 269: 17802-17808.
    • (1994) J Biol Chem , vol.269 , pp. 17802-17808
    • Fearon, K.1    McClendon, V.2    Bonetti, B.3    Bedwell, D.M.4
  • 25
    • 0025203579 scopus 로고
    • Identification of amino acids inserted during suppression of UAA and UGA termination codons at the gag-pol junction of Moloney murine leukemia virus
    • Feng YX, Copeland TD, Oroszlan S, Rein A, Levin JG, (1990) Identification of amino acids inserted during suppression of UAA and UGA termination codons at the gag-pol junction of Moloney murine leukemia virus. Proc Natl Acad Sci U S A 87: 8860-8863.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 8860-8863
    • Feng, Y.X.1    Copeland, T.D.2    Oroszlan, S.3    Rein, A.4    Levin, J.G.5
  • 26
    • 17444384877 scopus 로고    scopus 로고
    • Discrimination between defects in elongation fidelity and termination efficiency provides mechanistic insights into translational readthrough
    • Salas-Marco J, Bedwell DM, (2005) Discrimination between defects in elongation fidelity and termination efficiency provides mechanistic insights into translational readthrough. J Mol Biol 348: 801-815.
    • (2005) J Mol Biol , vol.348 , pp. 801-815
    • Salas-Marco, J.1    Bedwell, D.M.2
  • 27
    • 77956019364 scopus 로고    scopus 로고
    • A comprehensive analysis of translational missense errors in the yeast Saccharomyces cerevisiae
    • Kramer EB, Vallabhaneni H, Mayer LM, Farabaugh PJ, (2010) A comprehensive analysis of translational missense errors in the yeast Saccharomyces cerevisiae. RNA 16: 1797-1808.
    • (2010) RNA , vol.16 , pp. 1797-1808
    • Kramer, E.B.1    Vallabhaneni, H.2    Mayer, L.M.3    Farabaugh, P.J.4
  • 28
    • 0035830952 scopus 로고    scopus 로고
    • Structural origins of aminoglycoside specificity for prokaryotic ribosomes
    • Lynch SR, Puglisi JD, (2001) Structural origins of aminoglycoside specificity for prokaryotic ribosomes. J Mol Biol 306: 1037-1058.
    • (2001) J Mol Biol , vol.306 , pp. 1037-1058
    • Lynch, S.R.1    Puglisi, J.D.2
  • 29
    • 36749023383 scopus 로고    scopus 로고
    • Negamycin binds to the wall of the nascent chain exit tunnel of the 50S ribosomal subunit
    • Schroeder SJ, Blaha G, Moore PB, (2007) Negamycin binds to the wall of the nascent chain exit tunnel of the 50S ribosomal subunit. Antimicrob Agents Chemother 51: 4462-4465.
    • (2007) Antimicrob Agents Chemother , vol.51 , pp. 4462-4465
    • Schroeder, S.J.1    Blaha, G.2    Moore, P.B.3
  • 30
    • 0025313808 scopus 로고
    • Biological characterization of multidrug-resistant human colon carcinoma sublines induced/selected by two methods
    • Yang LY, Trujillo JM, (1990) Biological characterization of multidrug-resistant human colon carcinoma sublines induced/selected by two methods. Cancer Res 50: 3218-3225.
    • (1990) Cancer Res , vol.50 , pp. 3218-3225
    • Yang, L.Y.1    Trujillo, J.M.2
  • 31
  • 32
    • 0033942924 scopus 로고    scopus 로고
    • Nonsense-mediated decay mutants do not affect programmed -1 frameshifting
    • Bidou L, Stahl G, Hatin I, Namy O, Rousset JP, et al. (2000) Nonsense-mediated decay mutants do not affect programmed-1 frameshifting. RNA 6: 952-961.
    • (2000) RNA , vol.6 , pp. 952-961
    • Bidou, L.1    Stahl, G.2    Hatin, I.3    Namy, O.4    Rousset, J.P.5
  • 33
    • 0032969751 scopus 로고    scopus 로고
    • Establishment and characterization of 12 human colorectal-carcinoma cell lines
    • Oh JH, Ku JL, Yoon KA, Kwon HJ, Kim WH, et al. (1999) Establishment and characterization of 12 human colorectal-carcinoma cell lines. Int J Cancer 81: 902-910.
    • (1999) Int J Cancer , vol.81 , pp. 902-910
    • Oh, J.H.1    Ku, J.L.2    Yoon, K.A.3    Kwon, H.J.4    Kim, W.H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.