Cooperative therapeutic anti-tumor effect of IL-15 agonist ALT-803 and co-targeting soluble NKG2D ligand sMIC

Oncotarget

Volumn 7, Issue 1, 2016, Pages 814-830

  Basher, Fahmin ^a   Jeng, Emily K ^b   Wong, Hing ^b   Wu, Jennifer ^a,c,d  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b Altor BioScience   (United States)

^c MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^d CanCure LLC   (United States)

Author keywords

ALT 803; Soluble NKG2D; Therapy; Tumor

Indexed keywords

ALT 803; CYTOKINE RECEPTOR AGONIST; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY B10G5; NEUTRALIZING ANTIBODY; UNCLASSIFIED DRUG; ALT-803; ANTINEOPLASTIC AGENT; GAMMA INTERFERON; HLA ANTIGEN CLASS 1; INTERLEUKIN 15; KLRK1 PROTEIN, HUMAN; LIGAND; NATURAL KILLER CELL LECTIN LIKE RECEPTOR SUBFAMILY K; PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER SURVIVAL; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG EFFICACY; IN VIVO STUDY; INFANT; MALE; MONOTHERAPY; MOUSE; NATURAL KILLER CELL; NEOPLASM; NONHUMAN; PROTEIN EXPRESSION; AGONISTS; ANIMAL; CELL CULTURE; CELL SURVIVAL; COCULTURE; CYTOLOGY; DRUG EFFECTS; FLOW CYTOMETRY; HUMAN; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; NEOPLASMS; SPLEEN; TRANSGENIC MOUSE; TUMOR CELL LINE; TUMOR VOLUME;

ANIMALS; ANTIBODIES, NEUTRALIZING; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CELL LINE, TUMOR; CELL SURVIVAL; CELLS, CULTURED; COCULTURE TECHNIQUES; FLOW CYTOMETRY; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; INTERFERON-GAMMA; INTERLEUKIN-15; KILLER CELLS, NATURAL; LIGANDS; MALE; MICE, KNOCKOUT; MICE, TRANSGENIC; NEOPLASMS; NK CELL LECTIN-LIKE RECEPTOR SUBFAMILY K; PROTEINS; SPLEEN; TUMOR BURDEN;

EID: 85021858762     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/ONCOTARGET.6416     Document Type: Article

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