Two-compartment model of NK cell proliferation: Insights from population response to IL-15 stimulation

Journal of Immunology

Volumn 188, Issue 7, 2012, Pages 2981-2990

  Zhao, Yun M ^a,b   French, Anthony R ^a,b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WASHINGTON UNIVERSITY IN ST LOUIS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 15;

ANIMAL CELL; ARTICLE; CELL COUNT; CELL DEATH; CELL DIVISION; CELL EXPANSION; COMPARTMENT MODEL; CONTROLLED STUDY; FEMALE; LYMPHOCYTE PROLIFERATION; LYMPHOCYTE SUBPOPULATION; MATHEMATICAL MODEL; MOUSE; NATURAL KILLER CELL; NONHUMAN; PREDICTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS;

ANIMALS; CELL DIVISION; CHEMOTAXIS, LEUKOCYTE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; IMMUNITY, INNATE; INTERLEUKIN-15; KILLER CELLS, NATURAL; LYMPHOCYTE COUNT; MICE; MICE, INBRED C57BL; MODELS, IMMUNOLOGICAL; SPECIFIC PATHOGEN-FREE ORGANISMS;

EID: 84859400886     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1102989     Document Type: Article

References (31)

1. Orange, J. S. 2006. Human natural killer cell deficiencies. Curr. Opin. Allergy Clin. Immunol. 6: 399-409. (Pubitemid 44714151)
2. Bukowski, J. F., B. A. Woda, and R. M. Welsh. 1984. Pathogenesis of murine cytomegalovirus infection in natural killer cell-depleted mice. J. Virol. 52: 119-128. (Pubitemid 14000479)
3. French, A. R., and W. M. Yokoyama. 2003. Natural killer cells and viral infections. Curr. Opin. Immunol. 15: 45-51. (Pubitemid 35454191)
4. Biron, C. A., L. R. Turgiss, and R. M. Welsh. 1983. Increase in NK cell number and turnover rate during acute viral infection. J. Immunol. 131: 1539-1545. (Pubitemid 13048920)
5. Dokun, A. O., S. Kim, H. R. Smith, H. S. Kang, D. T. Chu, and W. M. Yokoyama. 2001. Specific and nonspecific NK cell activation during virus infection. Nat. Immunol. 2: 951-956. (Pubitemid 32976168)
6. Nguyen, K. B., T. P. Salazar-Mather, M. Y. Dalod, J. B. Van Deusen, X. Q. Wei, F. Y. Liew, M. A. Caligiuri, J. E. Durbin, and C. A. Biron. 2002. Coordinated and distinct roles for IFN-α β, IL-12, and IL-15 regulation of NK cell responses to viral infection. J. Immunol. 169: 4279-4287. (Pubitemid 35178200)
7. French, A. R., H. Sjölin, S. Kim, R. Koka, L. Yang, D. A. Young, C. Cerboni, E. Tomasello, A. Ma, E. Vivier, et al. 2006. DAP12 signaling directly augments proproliferative cytokine stimulation of NK cells during viral infections. J. Immunol. 177: 4981-4990. (Pubitemid 44527567)
8. Orange, J. S., and C. A. Biron. 1996. Characterization of early IL-12, IFN-alphabeta, and TNF effects on antiviral state and NK cell responses during murine cytomegalovirus infection. J. Immunol. 156: 4746-4756. (Pubitemid 26174459)
9. Geurs, T. L., Y. M. Zhao, E. B. Hill, and A. R. French. 2009. Ly49H engagement compensates for the absence of type I interferon signaling in stimulating NK cell proliferation during murine cytomegalovirus infection. J. Immunol. 183: 5830-5836.
10. Fehniger, T. A., K. Suzuki, A. Ponnappan, J. B. VanDeusen, M. A. Cooper, S. M. Florea, A. G. Freud, M. L. Robinson, J. Durbin, and M. A. Caligiuri. 2001. Fatal leukemia in interleukin 15 transgenic mice follows early expansions in natural killer and memory phenotype CD8+ T cells. J. Exp. Med. 193: 219-231. (Pubitemid 32524453)
11. Cooper, M. A., J. E. Bush, T. A. Fehniger, J. B. VanDeusen, R. E. Waite, Y. Liu, H. L. Aguila, and M. A. Caligiuri. 2002. In vivo evidence for a dependence on interleukin 15 for survival of natural killer cells. Blood 100: 3633-3638. (Pubitemid 35303933)
12. Ranson, T., C. A. Vosshenrich, E. Corcuff, O. Richard, W. Müller, and J. P. Di Santo. 2003. IL-15 is an essential mediator of peripheral NK-cell homeostasis. Blood 101: 4887-4893. (Pubitemid 36857750)
13. Kennedy, M. K., M. Glaccum, S. N. Brown, E. A. Butz, J. L. Viney, M. Embers, N. Matsuki, K. Charrier, L. Sedger, C. R. Willis, et al. 2000. Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice. J. Exp. Med. 191: 771-780.
14. Lodolce, J. P., D. L. Boone, S. Chai, R. E. Swain, T. Dassopoulos, S. Trettin, and A. Ma. 1998. IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation. Immunity 9: 669-676. (Pubitemid 28557595)
15. Kim, S., K. Iizuka, H. L. Aguila, I. L. Weissman, and W. M. Yokoyama. 2000. In vivo natural killer cell activities revealed by natural killer cell-deficient mice. Proc. Natl. Acad. Sci. USA 97: 2731-2736. (Pubitemid 30159240)
16. Tefferi, A., C. Y. Li, T. E. Witzig, M. V. Dhodapkar, S. H. Okuno, and R. L. Phyliky. 1994. Chronic natural killer cell lymphocytosis: a descriptive clinical study. Blood 84: 2721-2725. (Pubitemid 24317405)
17. French, A. R., S. Kim, T. A. Fehniger, J. R. Pratt, L. Yang, Y. J. Song, M. A. Caligiuri, and W. M. Yokoyama. 2007. Chronic lymphocytosis of functionally immature natural killer cells. J. Allergy Clin. Immunol. 120: 924-931. (Pubitemid 47531830)
18. Lima, M., J. Almeida, A. G. Montero, Mdos. A. Teixeira, M. L. Queirós, A. H. Santos, A. Balanzategui, A. Estevinho, Mdel. C. Algueró, P. Barcena, et al. 2004. Clinicobiological, immunophenotypic, and molecular characteristics of monoclonal CD56-/+dim chronic natural killer cell large granular lymphocytosis. Am. J. Pathol. 165: 1117-1127. (Pubitemid 39297719)
19. Gett, A. V., and P. D. Hodgkin. 2000. A cellular calculus for signal integration by T cells. Nat. Immunol. 1: 239-244.
20. De Boer, R. J., V. V. Ganusov, D. Milutinović, P. D. Hodgkin, and A. S. Perelson. 2006. Estimating lymphocyte division and death rates from CFSE data. Bull. Math. Biol. 68: 1011-1031. (Pubitemid 44195536)
21. Deenick, E. K., A. V. Gett, and P. D. Hodgkin. 2003. Stochastic model of T cell proliferation: a calculus revealing IL-2 regulation of precursor frequencies, cell cycle time, and survival. J. Immunol. 170: 4963-4972. (Pubitemid 36554725)
22. Ganusov, V. V., D. Milutinović, and R. J. De Boer. 2007. IL-2 regulates expansion of CD4+ T cell populations by affecting cell death: insights from modeling CFSE data. J. Immunol. 179: 950-957.
23. Mesecke, S., D. Urlaub, H. Busch, R. Eils, and C. Watzl. 2011. Integration of activating and inhibitory receptor signaling by regulated phosphorylation of Vav1 in immune cells. Sci. Signal. 4: ra36.
24. Fallon, E. M., and D. A. Lauffenburger. 2000. Computational model for effects of ligand/receptor binding properties on interleukin-2 trafficking dynamics and T cell proliferation response. Biotechnol. Prog. 16: 905-916.
25. Asquith, B., J. A. Borghans, V. V. Ganusov, and D. C. Macallan. 2009. Lymphocyte kinetics in health and disease. Trends Immunol. 30: 182-189.
26. Boehme, S. A., and M. J. Lenardo. 1993. Propriocidal apoptosis of mature T lymphocytes occurs at S phase of the cell cycle. Eur. J. Immunol. 23: 1552-1560. (Pubitemid 23218064)
27. Macallan, D. C., B. Asquith, A. J. Irvine, D. L. Wallace, A. Worth, H. Ghattas, Y. Zhang, G. E. Griffin, D. F. Tough, and P. C. Beverley. 2003. Measurement and modeling of human T cell kinetics. Eur. J. Immunol. 33: 2316-2326. (Pubitemid 37010049)
28. Tough, D. F., P. Borrow, and J. Sprent. 1996. Induction of bystander T cell proliferation by viruses and type I interferon in vivo. Science 272: 1947-1950. (Pubitemid 26234507)
29. Murali-Krishna, K., J. D. Altman, M. Suresh, D. Sourdive, A. Zajac, and R. Ahmed. 1998. In vivo dynamics of anti-viral CD8 T cell responses to different epitopes. An evaluation of bystander activation in primary and secondary responses to viral infection. Adv. Exp. Med. Biol. 452: 123-142. (Pubitemid 28478091)
30. Kaech, S. M., and R. Ahmed. 2001. Memory CD8+ T cell differentiation: initial antigen encounter triggers a developmental program in naïve cells. Nat. Immunol. 2: 415-422. (Pubitemid 33706139)
31. Wong, P., and E. G. Pamer. 2001. Cutting edge: antigen-independent CD8 T cell proliferation. J. Immunol. 166: 5864-5868. (Pubitemid 32440707)