Removal of abnormal myofilament O-GlcNAcylation restores Ca2+ sensitivity in diabetic cardiac muscle

Diabetes

Volumn 64, Issue 10, 2015, Pages 3573-3587

  Ramirez Correa, Genaro A ^a   Ma, Junfeng ^a   Slawson, Chad ^b   Zeidan, Quira ^a   Lugo Fagundo, Nahyr S ^a   Xu, Mingguo ^a   Shen, Xiaoxu ^a   Gao, Wei Dong ^a   Caceres, Viviane ^a   Chakir, Khalid ^a   DeVine, Lauren ^a   Cole, Robert N ^a   Marchionni, Luigi ^a   Paolocci, Nazareno ^a   Hart, Gerald W ^a   Murphy, Anne M ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA ACTIN; CALCIUM; MUSCLE PROTEIN; MYOSIN LIGHT CHAIN; MYOSIN LIGHT CHAIN 1; N ACETYLGLUCOSAMINE; O LINKED BETA N ACETYL DEXTRO GLUCOSAMINE; O LINKED BETA N ACETYL DEXTRO GLUCOSAMINE TRANSFERASE; TRANSFERASE; TROPOMYOSIN; UNCLASSIFIED DRUG; BETA N ACETYLHEXOSAMINIDASE;

ACYLATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIAC MUSCLE; CELLULAR DISTRIBUTION; COMPARATIVE STUDY; CONTROLLED STUDY; DIABETIC CARDIOMYOPATHY; HEART MUSCLE CONTRACTILITY; IN VIVO STUDY; INSULIN DEPENDENT DIABETES MELLITUS; MALE; MYOFILAMENT; NONHUMAN; O GLCNACYLATION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RAT; SARCOMERE; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; ANALOGS AND DERIVATIVES; ANIMAL; COMPLICATION; ENZYMOLOGY; EXPERIMENTAL DIABETES MELLITUS; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; MUSCLE FIBRIL; PATHOLOGY; SPRAGUE DAWLEY RAT; ULTRASTRUCTURE;

ACETYLGLUCOSAMINE; ANIMALS; BETA-N-ACETYLHEXOSAMINIDASES; CALCIUM; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC CARDIOMYOPATHIES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MALE; MYOCARDIUM; MYOFIBRILS; RATS; RATS, SPRAGUE-DAWLEY; SARCOMERES;

EID: 84949017406     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db14-1107     Document Type: Article

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