Inhibition of high-mobility group box 1 improves myocardial fibrosis and dysfunction in diabetic cardiomyopathy

International Journal of Cardiology

Volumn 172, Issue 1, 2014, Pages 202-212

  Wang, Wen Ke ^a   Wang, Ben ^a   Lu, Qing Hua ^b   Zhang, Wei ^a   Qin, Wei Dong ^a   Liu, Xiang Juan ^a   Liu, Xiao Qian ^a   An, Feng Shuang ^a   Zhang, Yun ^a   Zhang, Ming Xiang ^a  

^a SHANDONG UNIVERSITY   (China)

^b THE SECOND HOSPITAL OF SHANDONG UNIVERSITY   (China)

Author keywords

Cardiac fibroblasts; Diabetic cardiomyopathy; Fibrosis; High mobility group box 1

Indexed keywords

GELATINASE A; GELATINASE B; HIGH MOBILITY GROUP B1 PROTEIN; HMGB1 PROTEIN, MOUSE; MMP2 PROTEIN, MOUSE; MMP9 PROTEIN, MOUSE; SMALL INTERFERING RNA;

ANIMAL; C57BL MOUSE; CELL MOTION; CELL PROLIFERATION; CULTURE TECHNIQUE; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC CARDIOMYOPATHY; DISEASE MODEL; ECHOCARDIOGRAPHY; ECHOGRAPHY; FIBROSIS; GENETICS; HEART MUSCLE; HEART MUSCLE CELL; IMMUNOLOGY; METABOLISM; SIGNAL TRANSDUCTION;

ANIMALS; CELL CULTURE TECHNIQUES; CELL MOVEMENT; CELL PROLIFERATION; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC CARDIOMYOPATHIES; DISEASE MODELS, ANIMAL; ECHOCARDIOGRAPHY; FIBROSIS; HMGB1 PROTEIN; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MICE, INBRED C57BL; MYOCARDIUM; MYOCYTES, CARDIAC; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 84894101125     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2014.01.011     Document Type: Article

References (49)

1. F.S. Fein Diabetic cardiomyopathy Diabetes Care 13 1990 1169 1179
2. B.D. Hoit, C. Castro, G. Bultron, S. Knight, and M.A. Matlib Noninvasive evaluation of cardiac dysfunction by echocardiography in streptozotocin-induced diabetic rats J Card Fail 5 1999 324 333
3. C.M. Schannwell, M. Schneppenheim, S. Perings, G. Plehn, and B.E. Strauer Left ventricular diastolic dysfunction as an early manifestation of diabetic cardiomyopathy Cardiology 98 2002 33 39
4. M. Shimizu, K. Umeda, and N. Sugihara et al. Collagen remodelling in myocardia of patients with diabetes J Clin Pathol 46 1993 32 36
5. D. Westermann, S. Rutschow, and S. Jager et al. Contributions of inflammation and cardiac matrix metalloproteinase activity to cardiac failure in diabetic cardiomyopathy: the role of angiotensin type 1 receptor antagonism Diabetes 56 2007 641 646
6. L. Falciola, F. Spada, and S. Calogero et al. High mobility group 1 protein is not stably associated with the chromosomes of somatic cells J Cell Biol 137 1997 19 26
7. P. Scaffidi, T. Misteli, and M.E. Bianchi Release of chromatin protein HMGB1 by necrotic cells triggers inflammation Nature 418 2002 191 195
8. H. Wang, O. Bloom, and M. Zhang et al. HMG-1 as a late mediator of endotoxin lethality in mice Science 285 1999 248 251
9. H. Wang, J.M. Vishnubhakat, and O. Bloom et al. Proinflammatory cytokines (tumor necrosis factor and interleukin 1) stimulate release of high mobility group protein-1 by pituicytes Surgery 126 1999 389 392
10. S. Liu, D.B. Stolz, and P.L. Sappington et al. HMGB1 is secreted by immunostimulated enterocytes and contributes to cytomix-induced hyperpermeability of Caco-2 monolayers Am J Physiol Cell Physiol 290 2006 C990 C999
11. W. Li, A.E. Sama, and H. Wang Role of HMGB1 in cardiovascular diseases Curr Opin Pharmacol 6 2006 130 135
12. G.P. Sims, D.C. Rowe, S.T. Rietdijk, R. Herbst, and A.J. Coyle HMGB1 and RAGE in inflammation and cancer Annu Rev Immunol 28 2010 367 388
13. B. Degryse, T. Bonaldi, and P. Scaffidi et al. The high mobility group (HMG) boxes of the nuclear protein HMG1 induce chemotaxis and cytoskeleton reorganization in rat smooth muscle cells J Cell Biol 152 2001 1197 1206
14. H.C. Volz, Z. Kaya, H.A. Katus, and M. Andrassy The role of HMGB1/RAGE in inflammatory cardiomyopathy Semin Thromb Hemost 36 2010 185 194
15. Y. Cai, X. Hu, B. Yi, T. Zhang, and Z. Wen Glucagon-like peptide-1 receptor agonist protects against hyperglycemia-induced cardiocytes injury by inhibiting high mobility group box 1 expression Mol Biol Rep 39 2012 10705 10711
16. C. Li, F. Hua, and T. Ha et al. Activation of myocardial phosphoinositide-3-kinase p110alpha ameliorates cardiac dysfunction and improves survival in polymicrobial sepsis PLoS One 7 2012 e44712
17. F.F. Su, M.Q. Shi, and W.G. Guo et al. High-mobility group box 1 induces calcineurin-mediated cell hypertrophy in neonatal rat ventricular myocytes Mediators Inflamm 2012 2012 805149
18. M. Andrassy, H.C. Volz, and J.C. Igwe et al. High-mobility group box-1 in ischemia-reperfusion injury of the heart Circulation 117 2008 3216 3226
19. H.P. Tzeng, J. Fan, and J.G. Vallejo et al. Negative inotropic effects of high-mobility group box 1 protein in isolated contracting cardiac myocytes Am J Physiol Heart Circ Physiol 294 2008 H1490 H1496
20. H.C. Volz, C. Seidel, and D. Laohachewin et al. HMGB1: the missing link between diabetes mellitus and heart failure Basic Res Cardiol 105 2010 805 820
21. J. Kim, E. Sohn, C.S. Kim, K. Jo, and J.S. Kim The role of high-mobility group box-1 protein in the development of diabetic nephropathy Am J Nephrol 33 2011 524 529
22. N. Hamada, T. Maeyama, and T. Kawaguchi et al. The role of high mobility group box1 in pulmonary fibrosis Am J Respir Cell Mol Biol 39 2008 440 447
23. Y. Ti, G.L. Xie, and Z.H. Wang et al. TRB3 gene silencing alleviates diabetic cardiomyopathy in a type 2 diabetic rat model Diabetes 60 2011 2963 2974
24. J. Papakrivopoulou, G.E. Lindahl, J.E. Bishop, and G.J. Laurent Differential roles of extracellular signal-regulated kinase 1/2 and p38MAPK in mechanical load-induced procollagen alpha1(I) gene expression in cardiac fibroblasts Cardiovasc Res 61 2004 736 744
25. C.J. Li, L. Lv, H. Li, and D.M. Yu Cardiac fibrosis and dysfunction in experimental diabetic cardiomyopathy are ameliorated by alpha-lipoic acid Cardiovasc Diabetol 11 2012 73
26. P. Asavarut, H. Zhao, J. Gu, and D. Ma The role of HMGB1 in inflammation-mediated organ injury Acta Anaesthesiol Taiwan 51 2013 28 33
27. A. Taguchi, D.C. Blood, and G. del Toro et al. Blockade of RAGE-amphoterin signalling suppresses tumour growth and metastases Nature 405 2000 354 360
28. S. Devaraj, M.R. Dasu, S.H. Park, and I. Jialal Increased levels of ligands of Toll-like receptors 2 and 4 in type 1 diabetes Diabetologia 52 2009 1665 1668
29. X. Ye, M. Chopp, and X. Liu et al. Niaspan reduces high-mobility group box 1/receptor for advanced glycation endproducts after stroke in type-1 diabetic rats Neuroscience 190 2011 339 345
30. M. Rajesh, S. Batkai, and M. Kechrid et al. Cannabinoid 1 receptor promotes cardiac dysfunction, oxidative stress, inflammation, and fibrosis in diabetic cardiomyopathy Diabetes 61 2012 716 727
31. D.J. Sahn, A. DeMaria, J. Kisslo, and A. Weyman Recommendations regarding quantitation in M-mode echocardiography: results of a survey of echocardiographic measurements Circulation 58 1978 1072 1083
32. S. Ares-Carrasco, B. Picatoste, and A. Benito-Martin et al. Myocardial fibrosis and apoptosis, but not inflammation, are present in long-term experimental diabetes Am J Physiol Heart Circ Physiol 297 2009 H2109 H2119
33. I.G. Poornima, P. Parikh, and R.P. Shannon Diabetic cardiomyopathy: the search for a unifying hypothesis Circ Res 98 2006 596 605
34. M. Awazu, K. Ishikura, M. Hida, and M. Hoshiya Mechanisms of mitogen-activated protein kinase activation in experimental diabetes J Am Soc Nephrol 10 1999 738 745
35. O. Hori, J. Brett, and T. Slattery et al. The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. Mediation of neurite outgrowth and co-expression of rage and amphoterin in the developing nervous system J Biol Chem 270 1995 25752 25761
36. T. Kohno, T. Anzai, and K. Naito et al. Role of high-mobility group box 1 protein in post-infarction healing process and left ventricular remodelling Cardiovasc Res 81 2009 565 573
37. S. Muller, L. Ronfani, and M.E. Bianchi Regulated expression and subcellular localization of HMGB1, a chromatin protein with a cytokine function J Intern Med 255 2004 332 343
38. S. Gardella, C. Andrei, and D. Ferrera et al. The nuclear protein HMGB1 is secreted by monocytes via a non-classical, vesicle-mediated secretory pathway EMBO Rep 3 2002 995 1001
39. H. Xu, Z. Su, and J. Wu et al. The alarmin cytokine, high mobility group box 1, is produced by viable cardiomyocytes and mediates the lipopolysaccharide-induced myocardial dysfunction via a TLR4/ phosphatidylinositol 3-kinase gamma pathway J Immunol 184 2010 1492 1498
40. C.A. Souders, S.L. Bowers, and T.A. Baudino Cardiac fibroblast: the renaissance cell Circ Res 105 2009 1164 1176
41. V.P. Singh, K.M. Baker, and R. Kumar Activation of the intracellular renin-angiotensin system in cardiac fibroblasts by high glucose: role in extracellular matrix production Am J Physiol Heart Circ Physiol 294 2008 H1675 H1684
42. G.P. Vadla, and E. Vellaichamy Anti-fibrotic cardio protective efficacy of aminoguanidine against streptozotocin induced cardiac fibrosis and high glucose induced collagen up regulation in cardiac fibroblasts Chem Biol Interact 197 2012 119 128
43. Y. Li, J. Ma, and H. Zhu et al. Targeted inhibition of calpain reduces myocardial hypertrophy and fibrosis in mouse models of type 1 diabetes Diabetes 60 2011 2985 2994
44. Y. Hori, T. Kashimoto, and T. Yonezawa et al. Matrix metalloproteinase-2 stimulates collagen-I expression through phosphorylation of focal adhesion kinase in rat cardiac fibroblasts Am J Physiol Cell Physiol 303 2012 C947 C953
45. J.M. Nelson, T.M. Krummel, and J.H. Haynes et al. Operative techniques in the fetal rabbit J Invest Surg 3 1990 393 398
46. J. Qiu, J. Xu, and Y. Zheng et al. High-mobility group box 1 promotes metalloproteinase-9 upregulation through Toll-like receptor 4 after cerebral ischemia Stroke 41 2010 2077 2082
47. P. Lijnen, V. Petrov, K. Rumilla, and R. Fagard Transforming growth factor-beta 1 promotes contraction of collagen gel by cardiac fibroblasts through their differentiation into myofibroblasts Methods Find Exp Clin Pharmacol 25 2003 79 86
48. S. Neumann, K. Huse, and R. Semrau et al. Aldosterone and d-glucose stimulate the proliferation of human cardiac myofibroblasts in vitro Hypertension 39 2002 756 760
49. I. Shiojima, and K. Walsh Role of Akt signaling in vascular homeostasis and angiogenesis Circ Res 90 2002 1243 1250