Absence of the NOD2 protein renders epithelia more susceptible to barrier dysfunction due to mitochondrial dysfunction

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 313, Issue 1, 2017, Pages G26-G38

  Saxena, Alpana ^a   Lopes, Fernando ^a   Poon, Karen K H ^a   McKay, Derek M ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

Barrier; Commensal bacteria; Epithelium; Mitochondria; NOD2

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2,4 DINITROPHENOL; ADENOSINE TRIPHOSPHATE; CASPASE RECRUITMENT DOMAIN PROTEIN 15; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; REACTIVE OXYGEN METABOLITE; RNA 18S; DINITROPHENOL-OVALBUMIN; OVALBUMIN;

ANIMAL CELL; ARTICLE; AUTOPHAGY; BACTERIAL VIABILITY; COLON CELL; COLON EPITHELIUM; COMPARATIVE STUDY; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVATION; ESCHERICHIA COLI; GENE SILENCING; GENETIC SUSCEPTIBILITY; HT-29 CELL LINE; HUMAN; HUMAN CELL; INTERNALIZATION; INTESTINAL BARRIER DYSFUNCTION; INTESTINE FUNCTION DISORDER; LOSS OF FUNCTION MUTATION; MALE; MOLECULAR PATHOLOGY; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; SMALL INTESTINE EPITHELIUM; T84 CELL LINE; TRANSEPITHELIAL RESISTANCE; WILD TYPE MOUSE; ANIMAL; CELL LINE; CYTOPLASM; GENE EXPRESSION REGULATION; GENETICS; INTESTINE MUCOSA; KNOCKOUT MOUSE; METABOLISM; MITOCHONDRION; MOUSE; PHYSIOLOGY; TISSUE CULTURE TECHNIQUE;

ANIMALS; CELL LINE; DINITROPHENOLS; ESCHERICHIA COLI; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; HUMANS; INTESTINAL MUCOSA; MALE; MICE; MICE, KNOCKOUT; MITOCHONDRIA; MITOCHONDRIAL DISEASES; NOD2 SIGNALING ADAPTOR PROTEIN; ORGANOIDS; OVALBUMIN; RATS; TISSUE CULTURE TECHNIQUES;

EID: 85021725856     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00070.2017     Document Type: Article

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