-
1
-
-
67650021209
-
Microbial community profiling for human microbiome projects: Tools, techniques, and challenges
-
Hamady M, Knight R., Microbial community profiling for human microbiome projects: tools, techniques, and challenges. Genome Res. 2009; 19: 1141-1152.
-
(2009)
Genome Res
, vol.19
, pp. 1141-1152
-
-
Hamady, M.1
Knight, R.2
-
2
-
-
77955655862
-
Microbiota-stimulated immune mechanisms to maintain gut homeostasis
-
Chung H, Kasper DL., Microbiota-stimulated immune mechanisms to maintain gut homeostasis. Curr Opin Immunol. 2010; 22: 455-460.
-
(2010)
Curr Opin Immunol
, vol.22
, pp. 455-460
-
-
Chung, H.1
Kasper, D.L.2
-
3
-
-
0018855591
-
The colonic epithelium in ulcerative colitis: An energy-deficiency disease?
-
Roediger WE., The colonic epithelium in ulcerative colitis: an energy-deficiency disease ? Lancet. 1980; 2: 712-715. (Pubitemid 10060060)
-
(1980)
Lancet
, vol.2
, Issue.8197
, pp. 712-715
-
-
Roediger, W.E.W.1
-
4
-
-
70749123464
-
Towards a molecular risk map-recent advances on the etiology of inflammatory bowel disease
-
Rosenstiel P, Sina C, Franke A, et al. Towards a molecular risk map-recent advances on the etiology of inflammatory bowel disease. Semin Immunol. 2009; 21: 334-345.
-
(2009)
Semin Immunol
, vol.21
, pp. 334-345
-
-
Rosenstiel, P.1
Sina, C.2
Franke, A.3
-
5
-
-
76949094665
-
Future biologic targets for IBD:, potentials and pitfalls
-
Melmed GY, Targan SR., Future biologic targets for IBD:, potentials and pitfalls. Nat Rev Gastroenterol Hepatol. 2010; 7: 110-117.
-
(2010)
Nat Rev Gastroenterol Hepatol
, vol.7
, pp. 110-117
-
-
Melmed, G.Y.1
Targan, S.R.2
-
6
-
-
77953307288
-
Environmental risk factors for inflammatory bowel disease
-
Molodecky NA, Kaplan GG., Environmental risk factors for inflammatory bowel disease. Gastroenterol Hepatol. 2010; 6: 339-346.
-
(2010)
Gastroenterol Hepatol
, vol.6
, pp. 339-346
-
-
Molodecky, N.A.1
Kaplan, G.G.2
-
7
-
-
51849103168
-
The microbial and danger signals that activate Nod-like receptors
-
Benko S, Philpott DJ, Girardin SE., The microbial and danger signals that activate Nod-like receptors. Cytokine. 2008; 43: 368-373.
-
(2008)
Cytokine
, vol.43
, pp. 368-373
-
-
Benko, S.1
Philpott, D.J.2
Girardin, S.E.3
-
9
-
-
61749099040
-
Interferon-Î3 regulation of intestinal epithelial permeability
-
Beaurepaire C, Smyth D, McKay DM., Interferon-Î3 regulation of intestinal epithelial permeability. J Interferon Cytokine Res. 2009; 29: 133-144.
-
(2009)
J Interferon Cytokine Res
, vol.29
, pp. 133-144
-
-
Beaurepaire, C.1
Smyth, D.2
McKay, D.M.3
-
10
-
-
0033818743
-
Leaks in the epithelial barrier caused by spontaneous and TNF-α-induced single-cell apoptosis
-
Gitter AH, Bendfeldt K, Schulzke JD, et al. Leaks in the epithelial barrier caused by spontaneous and TNF-α-induced single-cell apoptosis. FASEB J. 2000; 14: 1749-1753.
-
(2000)
FASEB J
, vol.14
, pp. 1749-1753
-
-
Gitter, A.H.1
Bendfeldt, K.2
Schulzke, J.D.3
-
11
-
-
13244298599
-
Interferon-γ and tumor necrosis factor-β synergize to induce intestinal epithelial barrier dysfunction by up-regulating myosin light chain kinase expression
-
Wang F, Graham WV, Wang Y, et al. Interferon-Î3 and tumor necrosis factor-α synergize to induce intestinal epithelial barrier dysfunction by up-regulating myosin light chain kinase expression. Am J Pathol. 2005; 166: 409-419. (Pubitemid 40189038)
-
(2005)
American Journal of Pathology
, vol.166
, Issue.2
, pp. 409-419
-
-
Wang, F.1
Graham, W.V.2
Wang, Y.3
Witkowski, E.D.4
Schwarz, B.T.5
Turner, J.R.6
-
12
-
-
33845995125
-
Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn's disease
-
DOI 10.1136/gut.2006.094375
-
Zeissig S, Burgel N, Gunzel D, et al. Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn's disease. Gut. 2007; 56: 61-72. (Pubitemid 46044890)
-
(2007)
Gut
, vol.56
, Issue.1
, pp. 61-72
-
-
Zeissig, S.1
Burgel, N.2
Gunzel, D.3
Richter, J.4
Mankertz, J.5
Wahnschaffe, U.6
Kroesen, A.J.7
Zeitz, M.8
Fromm, M.9
Schulzke, J.-D.10
-
13
-
-
44649139179
-
Increased uptake of non-pathogenic E. coli via the follicle-associated epithelium in longstanding ileal Crohn's disease
-
DOI 10.1002/path.2337
-
Keita AV, Salim SY, Jiang T, et al. Increased uptake of non-pathogenic E. coli via the follicle-associated epithelium in longstanding ileal Crohn's disease. J Pathol. 2008; 215: 135-144. (Pubitemid 351786032)
-
(2008)
Journal of Pathology
, vol.215
, Issue.2
, pp. 135-144
-
-
Keita, A.V.1
Salim, S.Y.2
Jiang, T.3
Yang, P.-C.4
Franzen, L.5
Soderkvist, P.6
Magnusson, K.-E.7
Soderholm, J.D.8
-
14
-
-
1242316259
-
Epithelia under Metabolic Stress Perceive Commensal Bacteria as a Threat
-
Nazli A, Yang PC, Jury J, et al. Epithelia under metabolic stress perceive commensal bacteria as a threat. Am J Pathol. 2004; 164: 947-957. (Pubitemid 38235476)
-
(2004)
American Journal of Pathology
, vol.164
, Issue.3
, pp. 947-957
-
-
Nazli, A.1
Yang, P.-C.2
Jury, J.3
Howe, K.4
Watson, J.L.5
Soderholm, J.D.6
Sherman, P.M.7
Perdue, M.H.8
McKay, D.M.9
-
15
-
-
0033003669
-
Different intestinal permeability patterns in relatives and spouses of patients with Crohn's disease: An inherited defect in mucosal defence?
-
Soderholm JD, Olaison G, Lindberg E, et al. Different intestinal permeability patterns in relatives and spouses of patients with Crohn's disease: an inherited defect in mucosal defence ? Gut. 1999; 44: 96-100. (Pubitemid 29143287)
-
(1999)
Gut
, vol.44
, Issue.1
, pp. 96-100
-
-
Soderholm, J.D.1
Olaison, G.2
Lindberg, E.3
Hannestad, U.4
Vindels, A.5
Tysk, C.6
Jarnerot, G.7
Sjodahl, R.8
-
16
-
-
0032991667
-
Epithelial permeability to proteins in the noninflamed ileum of Crohn's disease?
-
DOI 10.1016/S0016-5085(99)70551-2
-
Soderholm JD, Peterson KH, Olaison G, et al. Epithelial permeability to proteins in the noninflamed ileum of Crohn's disease ? Gastroenterology. 1999; 117: 65-72. (Pubitemid 29297621)
-
(1999)
Gastroenterology
, vol.117
, Issue.1
, pp. 65-72
-
-
Soderholm, J.D.1
Peterson, K.H.2
Olaison, G.3
Franzen, L.E.4
Westrom, B.5
Magnusson, K.-E.6
Sjodahl, R.7
-
17
-
-
33847170623
-
Phosphatidylinositol 3'-kinase is a critical mediator of interferon-γ-induced increases in enteric epithelial permeability
-
DOI 10.1124/jpet.106.113639
-
McKay DM, Watson JL, Wang A, et al. Phosphatidylinositol 3'-kinase is a critical mediator of interferon-Î3-induced increases in enteric epithelial permeability. J Pharmacol Exp Ther. 2007; 320: 1013-1022. (Pubitemid 46294056)
-
(2007)
Journal of Pharmacology and Experimental Therapeutics
, vol.320
, Issue.3
, pp. 1013-1022
-
-
McKay, D.M.1
Watson, J.L.2
Wang, A.3
Caldwell, J.4
Prescott, D.5
Ceponis, P.M.J.6
Di Leo, V.7
Lu, J.8
-
18
-
-
9344264671
-
Increased epithelial uptake of protein antigens in the ileum of Crohn's disease mediated by tumour necrosis factor β
-
DOI 10.1136/gut.2004.041426
-
Soderholm JD, Streutker C, Yang PC, et al. Increased epithelial uptake of protein antigens in the ileum of Crohn's disease mediated by tumour necrosis factor-α. Gut. 2004; 53: 1817-1824. (Pubitemid 39556903)
-
(2004)
Gut
, vol.53
, Issue.12
, pp. 1817-1824
-
-
Soderholm, J.D.1
Streutker, C.2
Yang, P.-C.3
Paterson, C.4
Singh, P.K.5
McKay, D.M.6
Sherman, P.M.7
Croitoru, K.8
Perdue, M.H.9
-
19
-
-
19044381573
-
Interferon γ induces translocation of commensal Escherichia coli across gut epithelial cells via a lipid raft-mediated process
-
DOI 10.1053/j.gastro.2005.01.046, PII S0016508505001587
-
Clark E, Hoare C, Tanianis-Hughes J, et al. Interferon-Î3 induces translocation of commensal Escherichia coli across gut epithelial cells via a lipid raft-mediated process. Gastroenterology. 2005; 128: 1258-1267. (Pubitemid 40712177)
-
(2005)
Gastroenterology
, vol.128
, Issue.5
, pp. 1258-1267
-
-
Clark, E.1
Hoare, C.2
Tanianis-Hughes, J.3
Carlson, G.L.4
Warhurst, G.5
-
20
-
-
0345104218
-
Transepithelial transport processes at the intestinal mucosa in inflammatory bowel disease
-
DOI 10.1007/s003840050181
-
Schurmann G, Bruwer M, Klotz A, et al. Transepithelial transport processes at the intestinal mucosa in inflammatory bowel disease. Int J Colorectal Dis. 1999; 14: 41-46. (Pubitemid 29295302)
-
(1999)
International Journal of Colorectal Disease
, vol.14
, Issue.1
, pp. 41-46
-
-
Schurmann, G.1
Bruwer, M.2
Klotz, A.3
Schmid, K.W.4
Senninger, N.5
Zimmer, K.-P.6
-
21
-
-
61949313980
-
Intestinal barrier dysfunction in inflammatory bowel diseases
-
McGuckin MA, Eri R, Simms LA, et al. Intestinal barrier dysfunction in inflammatory bowel diseases. Inflamm Bowel Dis. 2009; 15: 100-113.
-
(2009)
Inflamm Bowel Dis
, vol.15
, pp. 100-113
-
-
McGuckin, M.A.1
Eri, R.2
Simms, L.A.3
-
22
-
-
78651339203
-
Importance of disrupted intestinal barrier in inflammatory bowel diseases
-
[Epub ahead of print]
-
Salim SY, Soderholm JD., Importance of disrupted intestinal barrier in inflammatory bowel diseases. Inflamm Bowel Dis. 2010; [Epub ahead of print].
-
(2010)
Inflamm Bowel Dis
-
-
Salim, S.Y.1
Soderholm, J.D.2
-
24
-
-
58249085436
-
Reducing small intestinal permeability attenuates colitis in the IL10 gene-deficient mouse
-
Arrieta MC, Madsen K, Doyle J, et al. Reducing small intestinal permeability attenuates colitis in the IL10 gene-deficient mouse. Gut. 2009; 58: 41-48.
-
(2009)
Gut
, vol.58
, pp. 41-48
-
-
Arrieta, M.C.1
Madsen, K.2
Doyle, J.3
-
25
-
-
33645049332
-
The primary defect in experimental ileitis originates from a nonhematopoietic source
-
Olson TS, Reuter BK, Scott KG, et al. The primary defect in experimental ileitis originates from a nonhematopoietic source. J Exp Med. 2006; 203: 541-552.
-
(2006)
J Exp Med
, vol.203
, pp. 541-552
-
-
Olson, T.S.1
Reuter, B.K.2
Scott, K.G.3
-
27
-
-
70349384629
-
Recent advances on the roles of NO in cancer and chronic inflammatory disorders
-
Kanwar JR, Kanwar RK, Burrow H, et al. Recent advances on the roles of NO in cancer and chronic inflammatory disorders. Curr Med Chem. 2009; 16: 2373-2394.
-
(2009)
Curr Med Chem
, vol.16
, pp. 2373-2394
-
-
Kanwar, J.R.1
Kanwar, R.K.2
Burrow, H.3
-
28
-
-
22144447861
-
Antioxidants as novel therapy in a murine model of colitis
-
DOI 10.1016/j.jnutbio.2004.09.007
-
Oz HS, Chen TS, McClain CJ, et al. Antioxidants as novel therapy in a murine model of colitis. J Nutr Biochem. 2005; 16: 297-304. (Pubitemid 41556919)
-
(2005)
Journal of Nutritional Biochemistry
, vol.16
, Issue.5
, pp. 297-304
-
-
Oz, H.S.1
Chen, T.S.2
McClain, C.J.3
De Villiers, W.J.S.4
-
29
-
-
26044457052
-
Expression of NOXI, a superoxide-generating NADPH oxidase, in colon cancer and inflammatory bowel disease
-
DOI 10.1002/path.1824
-
Szanto I, Rubbia-Brandt L, Kiss P, et al. Expression of NOX1, a superoxide-generating NADPH oxidase, in colon cancer and inflammatory bowel disease. J Pathol. 2005; 207: 164-176. (Pubitemid 41404147)
-
(2005)
Journal of Pathology
, vol.207
, Issue.2
, pp. 164-176
-
-
Szanto, I.1
Rubbia-Brandt, L.2
Kiss, P.3
Steger, K.4
Banfi, B.5
Kovari, E.6
Herrmann, F.7
Hadengue, A.8
Krause, K.-H.9
-
31
-
-
0036177947
-
Augmented increase in tight junction permeability by luminal stimuli in the non-inflamed ileum of crohn's disease
-
DOI 10.1136/gut.50.3.307
-
Soderholm JD, Olaison G, Peterson KH, et al. Augmented increase in tight junction permeability by luminal stimuli in the non-inflamed ileum of Crohn's disease. Gut. 2002; 50: 307-313. (Pubitemid 34161043)
-
(2002)
Gut
, vol.50
, Issue.3
, pp. 307-313
-
-
Soderholm, J.D.1
Olaison, G.2
Peterson, K.H.3
Franzen, L.E.4
Lindmark, T.5
Wiren, M.6
Tagesson, C.7
Sjodahl, R.8
-
32
-
-
33749638414
-
Comparative proteomic studies on the pathogenesis of human ulcerative colitis
-
Hsieh SY, Shih TC, Yeh CY, et al. Comparative proteomic studies on the pathogenesis of human ulcerative colitis. Proteomics. 2006; 6: 5322-5331.
-
(2006)
Proteomics
, vol.6
, pp. 5322-5331
-
-
Hsieh, S.Y.1
Shih, T.C.2
Yeh, C.Y.3
-
33
-
-
77954758654
-
The impact of the microbiota on the pathogenesis of IBD: Lessons from mouse infection models
-
Nell S, Suerbaum S, Josenhans C., The impact of the microbiota on the pathogenesis of IBD: lessons from mouse infection models. Nat Rev Microbiol. 2010; 8: 564-577.
-
(2010)
Nat Rev Microbiol
, vol.8
, pp. 564-577
-
-
Nell, S.1
Suerbaum, S.2
Josenhans, C.3
-
34
-
-
35348857386
-
Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases
-
DOI 10.1073/pnas.0706625104
-
Frank DN, St Amand AL, Feldman RA, et al. Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases. Proc Natl Acad Sci U S A. 2007; 104: 13780-13785. (Pubitemid 350003397)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.34
, pp. 13780-13785
-
-
Frank, D.N.1
St. Amand, A.L.2
Feldman, R.A.3
Boedeker, E.C.4
Harpaz, N.5
Pace, N.R.6
-
35
-
-
30944466824
-
Reduced diversity of faecal microbiota in Crohn's disease revealed by a metagenomic approach
-
DOI 10.1136/gut.2005.073817
-
Manichanh C, Rigottier-Gois L, Bonnaud E, et al. Reduced diversity of faecal microbiota in Crohn's disease revealed by a metagenomic approach. Gut. 2006; 55: 205-211. (Pubitemid 43117279)
-
(2006)
Gut
, vol.55
, Issue.2
, pp. 205-211
-
-
Manichanh, C.1
Rigottier-Gois, L.2
Bonnaud, E.3
Gloux, K.4
Pelletier, E.5
Frangeul, L.6
Nalin, R.7
Jarrin, C.8
Chardon, P.9
Marteau, P.10
Roca, J.11
Dore, J.12
-
36
-
-
70349488325
-
Low counts of Faecalibacterium prausnitzii in colitis microbiota
-
Sokol H, Seksik P, Furet JP, et al. Low counts of Faecalibacterium prausnitzii in colitis microbiota. Inflamm Bowel Dis. 2009; 15: 1183-1189.
-
(2009)
Inflamm Bowel Dis
, vol.15
, pp. 1183-1189
-
-
Sokol, H.1
Seksik, P.2
Furet, J.P.3
-
37
-
-
0034111016
-
Phylogenetic relationships of butyrate-producing bacteria from the human gut
-
DOI 10.1128/AEM.66.4.1654-1661.2000
-
Barcenilla A, Pryde SE, Martin JC, et al. Phylogenetic relationships of butyrate-producing bacteria from the human gut. Appl Environ Microbiol. 2000; 66: 1654-1661. (Pubitemid 30185646)
-
(2000)
Applied and Environmental Microbiology
, vol.66
, Issue.4
, pp. 1654-1661
-
-
Barcenilla, A.1
Pryde, S.E.2
Martin, J.C.3
Duncan, S.H.4
Stewart, C.S.5
Henderson, C.6
Flint, H.J.7
-
38
-
-
0033863238
-
Butyrate inhibits inflammatory responses through NFkappaB inhibition: Implications for Crohn's disease
-
Segain JP, Raingeard de la Bletiere D, Bourreille A, et al. Butyrate inhibits inflammatory responses through NFkappaB inhibition: implications for Crohn's disease. Gut. 2000; 47: 397-403.
-
(2000)
Gut
, vol.47
, pp. 397-403
-
-
Segain, J.P.1
Raingeard De La Bletiere, D.2
Bourreille, A.3
-
39
-
-
77950460778
-
The role of infection in the aetiology of inflammatory bowel disease
-
Hansen R, Thomson JM, El-Omar EM, et al. The role of infection in the aetiology of inflammatory bowel disease. J Gastroenterol. 2010; 45: 266-276.
-
(2010)
J Gastroenterol
, vol.45
, pp. 266-276
-
-
Hansen, R.1
Thomson, J.M.2
El-Omar, E.M.3
-
40
-
-
0036140777
-
Mucosal flora in inflammatory bowel disease
-
Swidsinski A, Ladhoff A, Pernthaler A, et al. Mucosal flora in inflammatory bowel disease. Gastroenterology. 2002; 122: 44-54. (Pubitemid 34049193)
-
(2002)
Gastroenterology
, vol.122
, Issue.1
, pp. 44-54
-
-
Swidsinski, A.1
Ladhoff, A.2
Pernthaler, A.3
Swidsinski, S.4
LoeningBaucke, V.5
Ortner, M.6
Weber, J.7
Hoffmann, U.8
Schreiber, S.9
Dietel, M.10
Lochs, H.11
-
41
-
-
4143069158
-
High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn's disease
-
DOI 10.1053/j.gastro.2004.04.061, PII S0016508504007711
-
Darfeuille-Michaud A, Boudeau J, Bulois P, et al. High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn's disease. Gastroenterology. 2004; 127: 412-421. (Pubitemid 39091889)
-
(2004)
Gastroenterology
, vol.127
, Issue.2
, pp. 412-421
-
-
Darfeuille-Michaud, A.1
Boudeau, J.2
Bulois, P.3
Neut, C.4
Glasser, A.-L.5
Barnich, N.6
Bringer, M.-A.7
Swidsinski, A.8
Beaugerie, L.9
Colombel, J.-F.10
-
42
-
-
0036207579
-
Clostridium difficile toxin A triggers human colonocyte IL-8 release via mitochondrial oxygen radical generation
-
He D, Sougioultzis S, Hagen S, et al. Clostridium difficile toxin A triggers human colonocyte IL-8 release via mitochondrial oxygen radical generation. Gastroenterology. 2002; 122: 1048-1057. (Pubitemid 34267287)
-
(2002)
Gastroenterology
, vol.122
, Issue.4
, pp. 1048-1057
-
-
He, D.1
Sougioultzis, S.2
Hagen, S.3
Liu, J.4
Keates, S.5
Keates, A.C.6
Pothoulakis, C.7
LaMont J.Thomas8
-
43
-
-
0034596826
-
Salmonella-induced caspase-2 activation in macrophages: A novel mechanism in pathogen-mediated apoptosis
-
Jesenberger V, Procyk KJ, Yuan J, et al. Salmonella-induced caspase-2 activation in macrophages: a novel mechanism in pathogen-mediated apoptosis. J Exp Med. 2000; 192: 1035-1046.
-
(2000)
J Exp Med
, vol.192
, pp. 1035-1046
-
-
Jesenberger, V.1
Procyk, K.J.2
Yuan, J.3
-
44
-
-
0019215731
-
Yersiniosis in children
-
Maki M, Vesikari T, Rantala I, et al. Yersiniosis in children. Arch Dis Child. 1980; 55: 861-865. (Pubitemid 11209427)
-
(1980)
Archives of Disease in Childhood
, vol.55
, Issue.11
, pp. 861-865
-
-
Maki, M.1
Vesikari, T.2
Rantala, I.3
Gronroos, P.4
-
45
-
-
33748449456
-
Citrobacter rodentium infection causes both mitochondrial dysfunction and intestinal epithelial barrier disruption in vivo: Role of mitochondrial associated protein (Map)
-
DOI 10.1111/j.1462-5822.2006.00741.x
-
Ma C, Wickham ME, Guttman JA, et al. Citrobacter rodentium infection causes both mitochondrial dysfunction and intestinal epithelial barrier disruption in vivo: role of mitochondrial associated protein (Map). Cell Microbiol. 2006; 8: 1669-1686. (Pubitemid 44350025)
-
(2006)
Cellular Microbiology
, vol.8
, Issue.10
, pp. 1669-1686
-
-
Ma, C.1
Wickham, M.E.2
Guttman, J.A.3
Deng, W.4
Walker, J.5
Madsen, K.L.6
Jacobson, K.7
Vogl, W.A.8
Finlay, B.B.9
Vallance, B.A.10
-
47
-
-
60649120752
-
Shigella induces mitochondrial dysfunction and cell death in nonmyleoid cells
-
Carneiro LA, Travassos LH, Soares F, et al. Shigella induces mitochondrial dysfunction and cell death in nonmyleoid cells. Cell Host Microbe. 2009; 5: 123-136.
-
(2009)
Cell Host Microbe
, vol.5
, pp. 123-136
-
-
Carneiro, L.A.1
Travassos, L.H.2
Soares, F.3
-
48
-
-
28044472243
-
Novel effects of the prototype translocating Escherichia coli, strain C25 on intestinal epithelial structure and barrier function
-
DOI 10.1111/j.1462-5822.2005.00595.x
-
Zareie M, Riff J, Donato K, et al. Novel effects of the prototype translocating Escherichia coli, strain C25 on intestinal epithelial structure and barrier function. Cell Microbiol. 2005; 7: 1782-1797. (Pubitemid 41685271)
-
(2005)
Cellular Microbiology
, vol.7
, Issue.12
, pp. 1782-1797
-
-
Zareie, M.1
Riff, J.2
Donato, K.3
McKay, D.M.4
Perdue, M.H.5
Soderholm, J.D.6
Karmali, M.7
Cohen, M.B.8
Hawkins, J.9
Sherman, P.M.10
-
49
-
-
56349142515
-
Tumor necrosis factor-α activates transcription of the NADPH oxidase organizer 1 (NOXO1) gene and upregulates superoxide production in colon epithelial cells
-
Kuwano Y, Tominaga K, Kawahara T, et al. Tumor necrosis factor-α activates transcription of the NADPH oxidase organizer 1 (NOXO1) gene and upregulates superoxide production in colon epithelial cells. Free Radic Biol Med. 2008; 45: 1642-1652.
-
(2008)
Free Radic Biol Med
, vol.45
, pp. 1642-1652
-
-
Kuwano, Y.1
Tominaga, K.2
Kawahara, T.3
-
50
-
-
77953380853
-
Tumor necrosis factor-α and apoptosis signal-regulating kinase 1 control reactive oxygen species release, mitochondrial autophagy, and c-Jun N-terminal kinase/p38 phosphorylation during necrotizing enterocolitis
-
Baregamian N, Song J, Bailey CE, et al. Tumor necrosis factor-α and apoptosis signal-regulating kinase 1 control reactive oxygen species release, mitochondrial autophagy, and c-Jun N-terminal kinase/p38 phosphorylation during necrotizing enterocolitis. Oxid Med Cell Longev. 2009; 2: 297-306.
-
(2009)
Oxid Med Cell Longev
, vol.2
, pp. 297-306
-
-
Baregamian, N.1
Song, J.2
Bailey, C.E.3
-
51
-
-
73449122227
-
Interleukin 10 inhibits interferon-Î3- and tumor necrosis factor-α-stimulated activation of NADPH oxidase 1 in human colonic epithelial cells and the mouse colon
-
Kamizato M, Nishida K, Masuda K, et al. Interleukin 10 inhibits interferon-Î3- and tumor necrosis factor-α-stimulated activation of NADPH oxidase 1 in human colonic epithelial cells and the mouse colon. J Gastroenterol. 2009; 44: 1172-1184.
-
(2009)
J Gastroenterol
, vol.44
, pp. 1172-1184
-
-
Kamizato, M.1
Nishida, K.2
Masuda, K.3
-
52
-
-
57449087458
-
Patients with inflammatory bowel disease may have a transforming growth factor-β-, interleukin (IL)-2- or IL-10-deficient state induced by intrinsic neutralizing antibodies
-
Ebert EC, Panja A, Das KM, et al. Patients with inflammatory bowel disease may have a transforming growth factor-β-, interleukin (IL)-2- or IL-10-deficient state induced by intrinsic neutralizing antibodies. Clin Exp Immunol. 2009; 155: 65-71.
-
(2009)
Clin Exp Immunol
, vol.155
, pp. 65-71
-
-
Ebert, E.C.1
Panja, A.2
Das, K.M.3
-
53
-
-
0031915148
-
Early lesions of recurrent Crohn's disease caused by infusion of intestinal contents in excluded ileum
-
DOI 10.1016/S0016-5085(98)70476-7
-
D'Haens GR, Geboes K, Peeters M, et al. Early lesions of recurrent Crohn's disease caused by infusion of intestinal contents in excluded ileum. Gastroenterology. 1998; 114: 262-267. (Pubitemid 28093532)
-
(1998)
Gastroenterology
, vol.114
, Issue.2
, pp. 262-267
-
-
D'Haens, G.R.1
Geboes, K.2
Peeters, M.3
Baert, F.4
Penninckx, F.5
Rutgeerts, P.6
-
55
-
-
0029814243
-
51Cr- ethylenediaminetetraacetic acid is increased after bilateral lower extremity ischemia-reperfusion in the rat
-
DOI 10.1016/S0039-6060(96)80076-6
-
Willoughby RP, Harris KA, Carson MW, et al. Intestinal mucosal permeability to 51Cr-ethylenediaminetetraacetic acid is increased after bilateral lower extremity ischemia-reperfusion in the rat. Surgery. 1996; 120: 547-553. (Pubitemid 26337132)
-
(1996)
Surgery
, vol.120
, Issue.3
, pp. 547-553
-
-
Willoughby, R.P.N.1
Harris, K.A.2
Carson, M.W.3
Martin, C.M.4
Troster, M.5
DeRose, G.6
Jamieson, W.G.7
Potter, R.F.8
-
56
-
-
77952092406
-
Hypoxia: An alarm signal during intestinal inflammation
-
Colgan SP, Taylor CT., Hypoxia: an alarm signal during intestinal inflammation. Nat Rev Gastroenterol Hepatol. 2010; 7: 281-287.
-
(2010)
Nat Rev Gastroenterol Hepatol
, vol.7
, pp. 281-287
-
-
Colgan, S.P.1
Taylor, C.T.2
-
57
-
-
0014872848
-
A comparative radiographic and pathological study of intestinal vaso-architecture in Crohn's disease and in ulcerative colitis
-
Brahme F, Lindstrom C., A comparative radiographic and pathological study of intestinal vaso-architecture in Crohn's disease and in ulcerative colitis. Gut. 1970; 11: 928-940.
-
(1970)
Gut
, vol.11
, pp. 928-940
-
-
Brahme, F.1
Lindstrom, C.2
-
58
-
-
0038449206
-
Acquired microvascular dysfunction in inflammatory bowel disease: Loss of nitric oxide-mediated vasodilation
-
DOI 10.1016/S0016-5085(03)00699-1
-
Hatoum OA, Binion DG, Otterson MF, et al. Acquired microvascular dysfunction in inflammatory bowel disease: loss of nitric oxide-mediated vasodilation. Gastroenterology. 2003; 125: 58-69. (Pubitemid 36799107)
-
(2003)
Gastroenterology
, vol.125
, Issue.1
, pp. 58-69
-
-
Hatoum, O.A.1
Binion, D.G.2
Otterson, M.F.3
Gutterman, D.D.4
-
59
-
-
73449101095
-
Hypoxia-induced downregulation of autophagy mediator Beclin 1 reduces the susceptibility of malignant intestinal epithelial cells to hypoxia-dependent apoptosis
-
Yoo BH, Wu X, Derouet M, et al. Hypoxia-induced downregulation of autophagy mediator Beclin 1 reduces the susceptibility of malignant intestinal epithelial cells to hypoxia-dependent apoptosis. Autophagy. 2009; 5: 1166-1179.
-
(2009)
Autophagy
, vol.5
, pp. 1166-1179
-
-
Yoo, B.H.1
Wu, X.2
Derouet, M.3
-
60
-
-
80051491083
-
Regulation of autophagy by ROS:, physiology and pathology
-
[Epub ahead of print]
-
Scherz-Shouval R, Elazar Z., Regulation of autophagy by ROS:, physiology and pathology. Trends Biochem Sci. 2010; [Epub ahead of print].
-
(2010)
Trends Biochem Sci
-
-
Scherz-Shouval, R.1
Elazar, Z.2
-
61
-
-
70349651858
-
Present status and strategy of NSAIDs-induced small bowel injury
-
Higuchi K, Umegaki E, Watanabe T, et al. Present status and strategy of NSAIDs-induced small bowel injury. J Gastroenterol. 2009; 44: 879-888.
-
(2009)
J Gastroenterol
, vol.44
, pp. 879-888
-
-
Higuchi, K.1
Umegaki, E.2
Watanabe, T.3
-
62
-
-
58849111794
-
Intestinal permeability in the pathogenesis of NSAID-induced enteropathy
-
Bjarnason I, Takeuchi K., Intestinal permeability in the pathogenesis of NSAID-induced enteropathy. J Gastroenterol. 2009; 44 (suppl 19): 23-29.
-
(2009)
J Gastroenterol
, vol.44
, Issue.SUPPL. 19
, pp. 23-29
-
-
Bjarnason, I.1
Takeuchi, K.2
-
63
-
-
77955886058
-
CPLA2 is protective against COX inhibitor-induced intestinal damage
-
Montrose DC, Kadaveru K, Ilsley JN, et al. cPLA2 is protective against COX inhibitor-induced intestinal damage. Toxicol Sci. 2010; 117: 122-132.
-
(2010)
Toxicol Sci
, vol.117
, pp. 122-132
-
-
Montrose, D.C.1
Kadaveru, K.2
Ilsley, J.N.3
-
64
-
-
0037099294
-
Indomethacin-induced mitochondrial dysfunction and oxidative stress in villus enterocytes
-
DOI 10.1016/S0006-2952(02)01067-5, PII S0006295202010675
-
Basivireddy J, Vasudevan A, Jacob M, et al. Indomethacin-induced mitochondrial dysfunction and oxidative stress in villus enterocytes. Biochem Pharmacol. 2002; 64: 339-349. (Pubitemid 34775312)
-
(2002)
Biochemical Pharmacology
, vol.64
, Issue.2
, pp. 339-349
-
-
Basivireddy, J.1
Vasudevan, A.2
Jacob, M.3
Balasubramanian, K.A.4
-
65
-
-
0034097624
-
Uncoupling of intestinal mitochondrial oxidative phosphorylation and inhibition of cyclooxygenase are required for the development of NSAID-enteropathy in the rat
-
DOI 10.1046/j.1365-2036.2000.00723.x
-
Somasundaram S, Sigthorsson G, Simpson RJ, et al. Uncoupling of intestinal mitochondrial oxidative phosphorylation and inhibition of cyclooxygenase are required for the development of NSAID-enteropathy in the rat. Aliment Pharmacol Ther. 2000; 14: 639-650. (Pubitemid 30240758)
-
(2000)
Alimentary Pharmacology and Therapeutics
, vol.14
, Issue.5
, pp. 639-650
-
-
Somasundaram, S.1
Sigthorsson, G.2
Simpson, R.J.3
Watts, J.4
Jacob, M.5
Tavares, I.A.6
Rafi, S.7
Roseth, A.8
Foster, R.9
Price, A.B.10
Wrigglesworth, J.M.11
Bjarnason, I.12
-
66
-
-
0031749892
-
The effect of tacrolimus (FK506) on intestinal barrier function and cellular energy production in humans
-
DOI 10.1016/S0016-5085(98)70366-X
-
Gabe SM, Bjarnason I, Tolou-Ghamari Z, et al. The effect of tacrolimus (FK506) on intestinal barrier function and cellular energy production in humans. Gastroenterology. 1998; 115: 67-74. (Pubitemid 28307289)
-
(1998)
Gastroenterology
, vol.115
, Issue.1
, pp. 67-74
-
-
Gabe, S.M.1
Bjarnason, I.2
Tolou-Ghamari, Z.3
Tredger, J.M.4
Johnson, P.G.5
Barclay, G.R.6
Williams, R.7
Silk, D.B.A.8
-
67
-
-
0029051550
-
FK506 increases permeability in rat intestine by inhibiting mitochondrial function
-
Madsen KL, Yanchar NL, Sigalet DL, et al. FK506 increases permeability in rat intestine by inhibiting mitochondrial function. Gastroenterology. 1995; 109: 107-114.
-
(1995)
Gastroenterology
, vol.109
, pp. 107-114
-
-
Madsen, K.L.1
Yanchar, N.L.2
Sigalet, D.L.3
-
68
-
-
0015853702
-
Toxicity of tetracyclines in rat-small-intestinal epithelium and liver
-
De Jonge HR., Toxicity of tetracyclines in rat-small-intestinal epithelium and liver. Biochem Pharmacol. 1973; 22: 2659-2677.
-
(1973)
Biochem Pharmacol
, vol.22
, pp. 2659-2677
-
-
De Jonge, H.R.1
-
69
-
-
80051513418
-
Life stress and gastro-intestinal diseases
-
Grace WJ., Life stress and gastro-intestinal diseases. Am Pract Dig Treat. 1953; 4: 848-852.
-
(1953)
Am Pract Dig Treat
, vol.4
, pp. 848-852
-
-
Grace, W.J.1
-
70
-
-
77956343420
-
A prospective population-based study of triggers of symptomatic flares in IBD
-
Bernstein CN, Singh S, Graff LA, et al. A prospective population-based study of triggers of symptomatic flares in IBD. Am J Gastroenterol. 2010; 105: 1994-2002.
-
(2010)
Am J Gastroenterol
, vol.105
, pp. 1994-2002
-
-
Bernstein, C.N.1
Singh, S.2
Graff, L.A.3
-
71
-
-
25444470762
-
Psychological stress in IBD: New insights into pathogenic and therapeutic implications
-
DOI 10.1136/gut.2005.064261
-
Mawdsley JE, Rampton DS., Psychological stress in IBD:, new insights into pathogenic and therapeutic implications. Gut. 2005; 54: 1481-1491. (Pubitemid 41375207)
-
(2005)
Gut
, vol.54
, Issue.10
, pp. 1481-1491
-
-
Mawdsley, J.E.1
Rampton, D.S.2
-
73
-
-
0342960436
-
Stress and gastrointestinal tract. II. Stress and intestinal barrier function
-
Soderholm JD, Perdue MH., Stress and gastrointestinal tract. II. Stress and intestinal barrier function. Am J Physiol Gastrointest Liver Physiol. 2001; 280: G7-G13.
-
(2001)
Am J Physiol Gastrointest Liver Physiol
, vol.280
-
-
Soderholm, J.D.1
Perdue, M.H.2
-
74
-
-
0023932010
-
Effect of cold-induced pain on salt and water transport in the human jejunum
-
Barclay GR, Turnberg LA., Effect of cold-induced pain on salt and water transport in the human jejunum. Gastroenterology. 1988; 94: 994-998.
-
(1988)
Gastroenterology
, vol.94
, pp. 994-998
-
-
Barclay, G.R.1
Turnberg, L.A.2
-
75
-
-
0031899530
-
Release of mast cell mediators into the jejunum by cold pain stress in humans
-
DOI 10.1016/S0016-5085(98)70577-3
-
Santos J, Saperas E, Nogueiras C, et al. Release of mast cell mediators into the jejunum by cold pain stress in humans. Gastroenterology. 1998; 114: 640-648. (Pubitemid 28160398)
-
(1998)
Gastroenterology
, vol.114
, Issue.4
, pp. 640-648
-
-
Santos, J.1
Saperas, E.2
Nogueiras, C.3
Mourelle, M.4
Antolin, M.5
Cadahia, A.6
Malagelada, J.-R.7
-
76
-
-
38349087186
-
Corticotropin-releasing hormone (CRH) regulates macromolecular permeability via mast cells in normal human colonic biopsies in vitro
-
Wallon C, Yang PC, Keita AV, et al. Corticotropin-releasing hormone (CRH) regulates macromolecular permeability via mast cells in normal human colonic biopsies in vitro. Gut. 2008; 57: 50-58.
-
(2008)
Gut
, vol.57
, pp. 50-58
-
-
Wallon, C.1
Yang, P.C.2
Keita, A.V.3
-
77
-
-
1642346289
-
Neonatal maternal deprivation triggers long term alterations in colonic epithelial barrier and mucosal immunity in rats
-
DOI 10.1136/gut.2003.024174
-
Barreau F, Ferrier L, Fioramonti J, et al. Neonatal maternal deprivation triggers long term alterations in colonic epithelial barrier and mucosal immunity in rats. Gut. 2004; 53: 501-506. (Pubitemid 38372973)
-
(2004)
Gut
, vol.53
, Issue.4
, pp. 501-506
-
-
Barreau, F.1
Ferrier, L.2
Fioramonti, J.3
Bueno, L.4
-
78
-
-
0033774021
-
Environmental stress-induced gastrointestinal permeability is mediated by endogenous glucocorticoids in the rat
-
Meddings JB, Swain MG., Environmental stress-induced gastrointestinal permeability is mediated by endogenous glucocorticoids in the rat. Gastroenterology. 2000; 119: 1019-1028.
-
(2000)
Gastroenterology
, vol.119
, pp. 1019-1028
-
-
Meddings, J.B.1
Swain, M.G.2
-
79
-
-
0028066768
-
Acute stressors stimulate ion secretion and increase epithelial permeability in rat intestine
-
Saunders PR, Kosecka U, McKay DM, et al. Acute stressors stimulate ion secretion and increase epithelial permeability in rat intestine. Am J Physiol. 1994; 267: G794-799.
-
(1994)
Am J Physiol
, vol.267
-
-
Saunders, P.R.1
Kosecka, U.2
McKay, D.M.3
-
80
-
-
1642354455
-
Increased antigen and bacterial uptake in follicle associated epithelium induced by chronic psychological stress in rats
-
DOI 10.1136/gut.2003.028506
-
Velin AK, Ericson AC, Braaf Y, et al. Increased antigen and bacterial uptake in follicle associated epithelium induced by chronic psychological stress in rats. Gut. 2004; 53: 494-500. (Pubitemid 38372972)
-
(2004)
Gut
, vol.53
, Issue.4
, pp. 494-500
-
-
Velin, A.K.1
Ericson, A.-C.2
Braaf, Y.3
Wallon, C.4
Soderholm, J.D.5
-
81
-
-
0036787474
-
Chronic stress induces mast cell-dependent bacterial adherence and initiates mucosal inflammation in rat intestine
-
Soderholm JD, Yang PC, Ceponis P, et al. Chronic stress induces mast cell-dependent bacterial adherence and initiates mucosal inflammation in rat intestine. Gastroenterology. 2002; 123: 1099-1108.
-
(2002)
Gastroenterology
, vol.123
, pp. 1099-1108
-
-
Soderholm, J.D.1
Yang, P.C.2
Ceponis, P.3
-
82
-
-
25644449654
-
Heightened responses to stressors in patients with inflammatory bowel disease
-
DOI 10.1111/j.1572-0241.2005.50071.x
-
Farhadi A, Keshavarzian A, Van de Kar LD, et al. Heightened responses to stressors in patients with inflammatory bowel disease. Am J Gastroenterol. 2005; 100: 1796-1804. (Pubitemid 41648436)
-
(2005)
American Journal of Gastroenterology
, vol.100
, Issue.8
, pp. 1796-1804
-
-
Farhadi, A.1
Keshavarzian, A.2
Van De Kar, L.D.3
Jakate, S.4
Domm, A.5
Zhang, L.6
Shaikh, M.7
Banan, A.8
Fields, J.Z.9
-
83
-
-
0347579845
-
Mitochondrial biogenesis in mammals: The role of endogenous nitric oxide
-
DOI 10.1126/science.1079368
-
Nisoli E, Clementi E, Paolucci C, et al. Mitochondrial biogenesis in mammals: the role of endogenous nitric oxide. Science. 2003; 299: 896-899. (Pubitemid 36182449)
-
(2003)
Science
, vol.299
, Issue.5608
, pp. 896-899
-
-
Nisoli, E.1
Clementi, E.2
Paolucci, C.3
Cozzi, V.4
Tonello, C.5
Sciorati, C.6
Bracale, R.7
Valerio, A.8
Francolini, M.9
Moncada, S.10
Carruba, M.O.11
-
84
-
-
29644435847
-
Enterocyte cytoskeleton changes are crucial for enhanced translocation of nonpathogenic Escherichia coli across metabolically stressed gut epithelia
-
DOI 10.1128/IAI.74.1.192-201.2006
-
Nazli A, Wang A, Steen O, et al. Enterocyte cytoskeleton changes are crucial for enhanced translocation of non-pathogenic Escherichia coli across metabolically stressed gut epithelia. Infect Immun. 2006; 74: 192-201. (Pubitemid 43023074)
-
(2006)
Infection and Immunity
, vol.74
, Issue.1
, pp. 192-201
-
-
Nazli, A.1
Wang, A.2
Steen, O.3
Prescott, D.4
Lu, J.5
Perdue, M.H.6
Soderholm, J.D.7
Sherman, P.M.8
McKay, D.M.9
-
85
-
-
77953721898
-
Enhanced translocation of bacteria across metabolically stressed epithelia is reduced by butyrate
-
Lewis K, Lutgendorff F, Phan V, et al. Enhanced translocation of bacteria across metabolically stressed epithelia is reduced by butyrate. Inflamm Bowel Dis. 2010; 16: 1138-1148.
-
(2010)
Inflamm Bowel Dis
, vol.16
, pp. 1138-1148
-
-
Lewis, K.1
Lutgendorff, F.2
Phan, V.3
-
86
-
-
41549135585
-
Decreased epithelial barrier function evoked by exposure to metabolic stress and nonpathogenic E. coli is enhanced by TNF-β
-
DOI 10.1152/ajpgi.00382.2007
-
Lewis K, Caldwell J, Phan V, et al. Decreased epithelial barrier function evoked by exposure to metabolic stress and non-pathogenic E. coli is enhanced by TNF-α. Am J Physiol Gastrointest Liver Physiol. 2008; 294: G669-678. (Pubitemid 351468760)
-
(2008)
American Journal of Physiology - Gastrointestinal and Liver Physiology
, vol.294
, Issue.3
-
-
Lewis, K.1
Caldwell, J.2
Phan, V.3
Prescott, D.4
Nazli, A.5
Wang, A.6
Soderholm, J.D.7
Perdue, M.H.8
Sherman, P.M.9
McKay, D.M.10
-
87
-
-
67249112674
-
Metabolic stress evokes decreases in epithelial barrier function
-
Lewis K, McKay DM., Metabolic stress evokes decreases in epithelial barrier function. Ann N Y Acad Sci. 2009; 1165: 327-337.
-
(2009)
Ann N y Acad Sci
, vol.1165
, pp. 327-337
-
-
Lewis, K.1
McKay, D.M.2
-
88
-
-
54949156390
-
Yersinia pseudotuberculosis induces transcytosis of nanoparticles across human intestinal villus epithelium via invasin-dependent macropinocytosis
-
Ragnarsson EG, Schoultz I, Gullberg E, et al. Yersinia pseudotuberculosis induces transcytosis of nanoparticles across human intestinal villus epithelium via invasin-dependent macropinocytosis. Lab Invest. 2008; 88: 1215-1226.
-
(2008)
Lab Invest
, vol.88
, pp. 1215-1226
-
-
Ragnarsson, E.G.1
Schoultz, I.2
Gullberg, E.3
-
90
-
-
43749092334
-
Intracellular redox status and oxidative stress: Implications for cell proliferation, apoptosis, and carcinogenesis
-
Mates JM, Segura JA, Alonso FJ, et al. Intracellular redox status and oxidative stress: implications for cell proliferation, apoptosis, and carcinogenesis. Arch Toxicol. 2008; 82: 273-299.
-
(2008)
Arch Toxicol
, vol.82
, pp. 273-299
-
-
Mates, J.M.1
Segura, J.A.2
Alonso, F.J.3
-
91
-
-
43949143804
-
The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy
-
Fujita N, Itoh T, Omori H, et al. The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy. Mol Biol Cell. 2008; 19: 2092-2100.
-
(2008)
Mol Biol Cell
, vol.19
, pp. 2092-2100
-
-
Fujita, N.1
Itoh, T.2
Omori, H.3
-
92
-
-
33846627302
-
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
-
DOI 10.1038/ng1954, PII NG1954
-
Hampe J, Franke A, Rosenstiel P, et al. A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn's disease in ATG16L1. Nat Genet. 2007; 39: 207-211. (Pubitemid 46184351)
-
(2007)
Nature Genetics
, vol.39
, Issue.2
, pp. 207-211
-
-
Hampe, J.1
Franke, A.2
Rosenstiel, P.3
Till, A.4
Teuber, M.5
Huse, K.6
Albrecht, M.7
Mayr, G.8
De La Vega, F.M.9
Briggs, J.10
Gunther, S.11
Prescott, N.J.12
Onnie, C.M.13
Hasler, R.14
Sipos, B.15
Folsch, U.R.16
Lengauer, T.17
Platzer, M.18
Mathew, C.G.19
Krawczak, M.20
Schreiber, S.21
more..
-
93
-
-
54849421128
-
Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated ATG16L1 variant
-
Kuballa P, Huett A, Rioux JD, et al. Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated ATG16L1 variant. PLoS One. 2008; 3: e3391.
-
(2008)
PLoS One
, vol.3
-
-
Kuballa, P.1
Huett, A.2
Rioux, J.D.3
-
94
-
-
56249135538
-
A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
-
Cadwell K, Liu JY, Brown SL, et al. A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells. Nature. 2008; 456: 259-263.
-
(2008)
Nature
, vol.456
, pp. 259-263
-
-
Cadwell, K.1
Liu, J.Y.2
Brown, S.L.3
-
95
-
-
77649194674
-
Crohn's disease-associated adherent-invasive E. coli are selectively favoured by impaired autophagy to replicate intracellularly
-
Lapaquette P, Glasser AL, Huett A, et al. Crohn's disease-associated adherent-invasive E. coli are selectively favoured by impaired autophagy to replicate intracellularly. Cell Microbiol. 2010; 12: 99-113.
-
(2010)
Cell Microbiol
, vol.12
, pp. 99-113
-
-
Lapaquette, P.1
Glasser, A.L.2
Huett, A.3
-
96
-
-
38049162157
-
Toll-like receptor 2 is protective of ischemia-reperfusion-mediated small-bowel injury in a murine model
-
Aprahamian CJ, Lorenz RG, Harmon CM, et al. Toll-like receptor 2 is protective of ischemia-reperfusion-mediated small-bowel injury in a murine model. Pediatr Crit Care Med. 2008; 9: 105-109.
-
(2008)
Pediatr Crit Care Med
, vol.9
, pp. 105-109
-
-
Aprahamian, C.J.1
Lorenz, R.G.2
Harmon, C.M.3
-
97
-
-
70350380878
-
DUOX2-derived reactive oxygen species are effectors of NOD2-mediated antibacterial responses
-
Lipinski S, Till A, Sina C, et al. DUOX2-derived reactive oxygen species are effectors of NOD2-mediated antibacterial responses. J Cell Sci. 2009; 122: 3522-3530.
-
(2009)
J Cell Sci
, vol.122
, pp. 3522-3530
-
-
Lipinski, S.1
Till, A.2
Sina, C.3
-
98
-
-
77649179433
-
NLRP3 inflammasome activation: The convergence of multiple signalling pathways on ROS production
-
Tschopp J, Schroder K., NLRP3 inflammasome activation: the convergence of multiple signalling pathways on ROS production ? Nat Rev Immunol. 2010; 10: 210-215.
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 210-215
-
-
Tschopp, J.1
Schroder, K.2
-
99
-
-
58149159542
-
Common variants in the NLRP3 region contribute to Crohn's disease susceptibility
-
Villani AC, Lemire M, Fortin G, et al. Common variants in the NLRP3 region contribute to Crohn's disease susceptibility. Nat Genet. 2009; 41: 71-76.
-
(2009)
Nat Genet
, vol.41
, pp. 71-76
-
-
Villani, A.C.1
Lemire, M.2
Fortin, G.3
-
100
-
-
66949174089
-
Combined polymorphisms in genes encoding the inflammasome components NALP3 and CARD8 confer susceptibility to Crohn's disease in Swedish men
-
Schoultz I, Verma D, Halfvarsson J, et al. Combined polymorphisms in genes encoding the inflammasome components NALP3 and CARD8 confer susceptibility to Crohn's disease in Swedish men. Am J Gastroenterol. 2009; 104: 1180-1188.
-
(2009)
Am J Gastroenterol
, vol.104
, pp. 1180-1188
-
-
Schoultz, I.1
Verma, D.2
Halfvarsson, J.3
-
102
-
-
57449084031
-
Combined butyric acid/mesalazine treatment in ulcerative colitis with mild-moderate activity. Results of a multicentre pilot study
-
Assisi RF., Combined butyric acid/mesalazine treatment in ulcerative colitis with mild-moderate activity. Results of a multicentre pilot study. Minerva Gastroenterol Dietol. 2008; 54: 231-238.
-
(2008)
Minerva Gastroenterol Dietol
, vol.54
, pp. 231-238
-
-
Assisi, R.F.1
-
103
-
-
34047148411
-
A new oral formulation for the release of sodium butyrate in the ileo-cecal region and colon
-
Roda A, Simoni P, Magliulo M, et al. A new oral formulation for the release of sodium butyrate in the ileo-cecal region and colon. World J Gastroenterol. 2007; 13: 1079-1084. (Pubitemid 46511010)
-
(2007)
World Journal of Gastroenterology
, vol.13
, Issue.7
, pp. 1079-1084
-
-
Roda, A.1
Simoni, P.2
Magliulo, M.3
Nanni, P.4
Baraldini, M.5
Roda, G.6
Roda, E.7
-
104
-
-
34347223232
-
Anti-inflammatory properties of the short-chain fatty acids acetate and propionate: A study with relevance to inflammatory bowel disease
-
Tedelind S, Westberg F, Kjerrulf M, et al. Anti-inflammatory properties of the short-chain fatty acids acetate and propionate: a study with relevance to inflammatory bowel disease. World J Gastroenterol. 2007; 13: 2826-2832. (Pubitemid 47007897)
-
(2007)
World Journal of Gastroenterology
, vol.13
, Issue.20
, pp. 2826-2832
-
-
Tedelind, S.1
Westberg, F.2
Kjerrulf, M.3
Vidal, A.4
-
105
-
-
36549003678
-
Down-Regulation of the Monocarboxylate Transporter 1 Is Involved in Butyrate Deficiency During Intestinal Inflammation
-
DOI 10.1053/j.gastro.2007.08.041, PII S0016508507014977
-
Thibault R, De Coppet P, Daly K, et al. Down-regulation of the monocarboxylate transporter 1 is involved in butyrate deficiency during intestinal inflammation. Gastroenterology. 2007; 133: 1916-1927. (Pubitemid 350180798)
-
(2007)
Gastroenterology
, vol.133
, Issue.6
, pp. 1916-1927
-
-
Thibault, R.1
De Coppet, P.2
Daly, K.3
Bourreille, A.4
Cuff, M.5
Bonnet, C.6
Mosnier, J.7
Galmiche, J.8
Shirazi-Beechey, S.9
Segain, J.10
-
106
-
-
77949538579
-
Butyrate utilization by the colonic mucosa in inflammatory bowel diseases: A transport deficiency
-
Thibault R, Blachier F, Darcy-Vrillon B, et al. Butyrate utilization by the colonic mucosa in inflammatory bowel diseases: a transport deficiency. Inflamm Bowel Dis. 2010; 16: 684-695.
-
(2010)
Inflamm Bowel Dis
, vol.16
, pp. 684-695
-
-
Thibault, R.1
Blachier, F.2
Darcy-Vrillon, B.3
-
107
-
-
0029836444
-
Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-κB abrogates established experimental colitis in mice
-
DOI 10.1038/nm0996-998
-
Neurath MF, Pettersson S, Meyer zum Buschenfelde KH, et al. Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-κB abrogates established experimental colitis in mice. Nat Med. 1996; 2: 998-1004. (Pubitemid 26306838)
-
(1996)
Nature Medicine
, vol.2
, Issue.9
, pp. 998-1004
-
-
Neurath, M.F.1
Pettersson, S.2
Meyer Zum Buschenfelde, K.-H.3
Strober, W.4
-
108
-
-
38849098412
-
NF-κB and the intestine: Friend or foe
-
Karrash T, Jobin C., NF-κB and the intestine: friend or foe ? Inflamm Bowel Dis. 2008; 14: 114-124.
-
(2008)
Inflamm Bowel Dis
, vol.14
, pp. 114-124
-
-
Karrash, T.1
Jobin, C.2
-
109
-
-
77955266918
-
Rapid uptake of lipophilic triphenylphosphonium cations by mitochondria in vivo following intravenous injection: Implications for mitochondria-specific therapies and probes
-
Porteous CM, Logan A, Evans C, et al. Rapid uptake of lipophilic triphenylphosphonium cations by mitochondria in vivo following intravenous injection: Implications for mitochondria-specific therapies and probes. Biochim Biophys Acta. 2010; 1800: 1009-1017.
-
(2010)
Biochim Biophys Acta
, vol.1800
, pp. 1009-1017
-
-
Porteous, C.M.1
Logan, A.2
Evans, C.3
-
110
-
-
0035895888
-
Selective targeting of a redox-active ubiquinone to mitochondria within cells: Antioxidant and antiapoptotic properties
-
Kelso GF, Porteous CM, Coulter CV, et al. Selective targeting of a redox-active ubiquinone to mitochondria within cells: antioxidant and antiapoptotic properties. J Biol Chem. 2001; 276: 4588-4596.
-
(2001)
J Biol Chem
, vol.276
, pp. 4588-4596
-
-
Kelso, G.F.1
Porteous, C.M.2
Coulter, C.V.3
-
111
-
-
77955283395
-
Animal and human studies with the mitochondria-targeted antioxidant MitoQ
-
Smith RA, Murphy MP., Animal and human studies with the mitochondria-targeted antioxidant MitoQ. Ann N Y Acad Sci. 2010; 1201: 96-103.
-
(2010)
Ann N y Acad Sci
, vol.1201
, pp. 96-103
-
-
Smith, R.A.1
Murphy, M.P.2
-
112
-
-
77953290939
-
Therapeutic prospects for mitochondrial disease
-
Schon EA, Dimauro S, Hirano M, et al. Therapeutic prospects for mitochondrial disease. Trends Mol Med. 2010; 16: 268-276.
-
(2010)
Trends Mol Med
, vol.16
, pp. 268-276
-
-
Schon, E.A.1
Dimauro, S.2
Hirano, M.3
|