메뉴 건너뛰기




Volumn 23, Issue , 2014, Pages 79-87

Nicotinamide phosphoribosyltransferase can affect metastatic activity and cell adhesive functions by regulating integrins in breast cancer

Author keywords

Breast cancer; Integrins; Metastasis; NAD+ salvage pathway; NAMPT; v 3

Indexed keywords

BETA1 INTEGRIN; INTEGRIN; LENTIVIRUS VECTOR; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; SCLEROPROTEIN; VITRONECTIN RECEPTOR; CYTOKINE; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE, HUMAN; VITRONECTIN;

EID: 84917696252     PISSN: 15687864     EISSN: 15687856     Source Type: Journal    
DOI: 10.1016/j.dnarep.2014.08.006     Document Type: Article
Times cited : (37)

References (66)
  • 1
    • 84867877340 scopus 로고    scopus 로고
    • The NAD metabolome - a key determinant of cancer cell biology
    • Chiarugi A., Dölle C., Felici R., Ziegler M. The NAD metabolome - a key determinant of cancer cell biology. Nat. Rev. Cancer 2012, 12:1-12.
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 1-12
    • Chiarugi, A.1    Dölle, C.2    Felici, R.3    Ziegler, M.4
  • 2
    • 77952541985 scopus 로고    scopus 로고
    • Vitamin B3, the nicotinamide adenine dinucleotides and aging
    • Xu P., Sauve A.A. Vitamin B3, the nicotinamide adenine dinucleotides and aging. Mech. Ageing Dev. 2010, 131:287-298.
    • (2010) Mech. Ageing Dev. , vol.131 , pp. 287-298
    • Xu, P.1    Sauve, A.A.2
  • 3
    • 77649295811 scopus 로고    scopus 로고
    • + metabolite levels as a function of vitamins and calorie restriction: evidence for different mechanisms of longevity
    • + metabolite levels as a function of vitamins and calorie restriction: evidence for different mechanisms of longevity. BMC Chem. Biol. 2010, 10(2).
    • (2010) BMC Chem. Biol. , vol.10 , Issue.2
    • Evans, C.1
  • 4
    • 50949120914 scopus 로고    scopus 로고
    • + precursor vitamins in human nutrition
    • + precursor vitamins in human nutrition. Annu. Rev. Nutr. 2008, 28:115-130.
    • (2008) Annu. Rev. Nutr. , vol.28 , pp. 115-130
    • Bogan, K.L.1    Brenner, C.2
  • 5
    • 84883491871 scopus 로고    scopus 로고
    • The importance of NAMPT/NAD/SIRT1 in the systemic regulation of metabolism and ageing
    • Imai S., Yoshino J. The importance of NAMPT/NAD/SIRT1 in the systemic regulation of metabolism and ageing. Diabetes Obes. Metab. 2013, 15(Suppl. 3):26-33.
    • (2013) Diabetes Obes. Metab. , vol.15 , pp. 26-33
    • Imai, S.1    Yoshino, J.2
  • 6
    • 62149150332 scopus 로고    scopus 로고
    • Niacin status, NAD distribution and ADP-ribose metabolism
    • Kirkland J.B. Niacin status, NAD distribution and ADP-ribose metabolism. Curr. Pharm. Des. 2009, 15:3-11.
    • (2009) Curr. Pharm. Des. , vol.15 , pp. 3-11
    • Kirkland, J.B.1
  • 7
    • 84874635096 scopus 로고    scopus 로고
    • +/NADH balance regulate breast cancer progression
    • +/NADH balance regulate breast cancer progression. J. Clin. Invest. 2013, 3.
    • (2013) J. Clin. Invest. , vol.3
    • Santidrian, A.F.1
  • 8
    • 34247520466 scopus 로고    scopus 로고
    • + synthesis
    • + synthesis. Cell 2007, 129:453-454.
    • (2007) Cell , vol.129 , pp. 453-454
    • Denu, J.M.1
  • 10
    • 75149160970 scopus 로고    scopus 로고
    • The nicotinamide phosphoribosyltransferase: a molecular link between metabolism, inflammation, and cancer
    • Gallí M., Van Gool F., Rongvaux A., Andris F., Leo O. The nicotinamide phosphoribosyltransferase: a molecular link between metabolism, inflammation, and cancer. Cancer Res. 2010, 70:8-11.
    • (2010) Cancer Res. , vol.70 , pp. 8-11
    • Gallí, M.1    Van Gool, F.2    Rongvaux, A.3    Andris, F.4    Leo, O.5
  • 11
    • 84881367747 scopus 로고    scopus 로고
    • Medicinal chemistry of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors
    • Galli U., et al. Medicinal chemistry of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors. J. Med. Chem. 2013, 56:6279-6296.
    • (2013) J. Med. Chem. , vol.56 , pp. 6279-6296
    • Galli, U.1
  • 13
    • 33748939380 scopus 로고    scopus 로고
    • Distinct patterns of DNA copy number alteration are associated with different clinicopathological features and gene-expression subtypes of breast cancer
    • Bergamaschi A., et al. Distinct patterns of DNA copy number alteration are associated with different clinicopathological features and gene-expression subtypes of breast cancer. Genes. Chromosomes Cancer 2006, 45:1033-1040.
    • (2006) Genes. Chromosomes Cancer , vol.45 , pp. 1033-1040
    • Bergamaschi, A.1
  • 14
    • 0026335799 scopus 로고
    • Accumulation of genetic alterations and progression of primary breast cancer
    • Sato T., Akiyama F., Sakamoto G., Kasumi F., Nakamura Y. Accumulation of genetic alterations and progression of primary breast cancer. Cancer Res. 1991, 51:5794-5799.
    • (1991) Cancer Res. , vol.51 , pp. 5794-5799
    • Sato, T.1    Akiyama, F.2    Sakamoto, G.3    Kasumi, F.4    Nakamura, Y.5
  • 15
    • 79955497591 scopus 로고    scopus 로고
    • Genomic differences between estrogen receptor (ER)-positive and ER-negative human breast carcinoma identified by single nucleotide polymorphism array comparative genome hybridization analysis
    • Fang M., et al. Genomic differences between estrogen receptor (ER)-positive and ER-negative human breast carcinoma identified by single nucleotide polymorphism array comparative genome hybridization analysis. Cancer 2011, 117:2024-2034.
    • (2011) Cancer , vol.117 , pp. 2024-2034
    • Fang, M.1
  • 16
    • 9244248684 scopus 로고    scopus 로고
    • Array comparative genomic hybridization analysis of genomic alterations in breast cancer subtypes
    • Loo L.W.M., et al. Array comparative genomic hybridization analysis of genomic alterations in breast cancer subtypes. Cancer Res. 2004, 64:8541-8549.
    • (2004) Cancer Res. , vol.64 , pp. 8541-8549
    • Loo, L.W.M.1
  • 17
    • 0003186859 scopus 로고
    • Enzymic synthesis of coenzyme I in relation to chemical control of cell growth
    • Morton R.K. Enzymic synthesis of coenzyme I in relation to chemical control of cell growth. Nature 1958, 181:540-542.
    • (1958) Nature , vol.181 , pp. 540-542
    • Morton, R.K.1
  • 18
    • 0037915696 scopus 로고
    • Comparative rates of synthesis in diphosphopyridine nucleotide by normal and tumour tissue from mouse mammary gland: studies with isolated nuclei
    • Branster M.V., Morton R. Comparative rates of synthesis in diphosphopyridine nucleotide by normal and tumour tissue from mouse mammary gland: studies with isolated nuclei. Biochem. J. 1956, 63:640.
    • (1956) Biochem. J. , vol.63 , pp. 640
    • Branster, M.V.1    Morton, R.2
  • 19
    • 77954274504 scopus 로고    scopus 로고
    • The PARP side of the nucleus: molecular actions, physiological outcomes, and clinical targets
    • Krishnakumar R., Kraus W.L. The PARP side of the nucleus: molecular actions, physiological outcomes, and clinical targets. Mol. Cell 2010, 39:8-24.
    • (2010) Mol. Cell , vol.39 , pp. 8-24
    • Krishnakumar, R.1    Kraus, W.L.2
  • 20
    • 84867085097 scopus 로고    scopus 로고
    • Synthetic lethality of PARP and NAMPT inhibition in triple-negative breast cancer cells
    • Bajrami I., et al. Synthetic lethality of PARP and NAMPT inhibition in triple-negative breast cancer cells. EMBO Mol. Med. 2012, 4:1087-1096.
    • (2012) EMBO Mol. Med. , vol.4 , pp. 1087-1096
    • Bajrami, I.1
  • 21
    • 73449133720 scopus 로고    scopus 로고
    • Nicotinamide phosphoribosyltransferase regulates cell survival through autophagy in cardiomyocytes
    • Hsu C.P., Hariharan N., Alcendor R.R., Oka S., Sadoshima J. Nicotinamide phosphoribosyltransferase regulates cell survival through autophagy in cardiomyocytes. Autophagy 2009, 5:1229-1231.
    • (2009) Autophagy , vol.5 , pp. 1229-1231
    • Hsu, C.P.1    Hariharan, N.2    Alcendor, R.R.3    Oka, S.4    Sadoshima, J.5
  • 22
    • 0242526050 scopus 로고    scopus 로고
    • A highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis
    • Hasmann M., Schemainda I.F.K866 a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis. Cancer Res. 2003, 63:7436-7442.
    • (2003) Cancer Res. , vol.63 , pp. 7436-7442
    • Hasmann, M.1    Schemainda, I.F.K.2
  • 23
    • 79952007931 scopus 로고    scopus 로고
    • NAMPT overexpression in prostate cancer and its contribution to tumor cell survival and stress response
    • Wang B., et al. NAMPT overexpression in prostate cancer and its contribution to tumor cell survival and stress response. Oncogene 2011, 30:907-921.
    • (2011) Oncogene , vol.30 , pp. 907-921
    • Wang, B.1
  • 24
    • 0037278885 scopus 로고    scopus 로고
    • Integrin adhesion receptors in tumor metastasis
    • Felding-Habermann B. Integrin adhesion receptors in tumor metastasis. Clin. Exp. Metastasis 2003, 20:203-213.
    • (2003) Clin. Exp. Metastasis , vol.20 , pp. 203-213
    • Felding-Habermann, B.1
  • 25
    • 7944230540 scopus 로고    scopus 로고
    • The emergence of integrins: a personal and historical perspective
    • Hynes R.O. The emergence of integrins: a personal and historical perspective. Matrix Biol. 2004, 23:333-340.
    • (2004) Matrix Biol. , vol.23 , pp. 333-340
    • Hynes, R.O.1
  • 26
    • 10344232014 scopus 로고    scopus 로고
    • Combinatorial antibody libraries from cancer patients yield ligand-mimetic Arg-Gly-Asp-containing immunoglobulins that inhibit breast cancer metastasis
    • Felding-Habermann B., et al. Combinatorial antibody libraries from cancer patients yield ligand-mimetic Arg-Gly-Asp-containing immunoglobulins that inhibit breast cancer metastasis. Proc. Natl. Acad. Sci. U. S. A. 2004, 101:17210-17215.
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 17210-17215
    • Felding-Habermann, B.1
  • 27
    • 0020443979 scopus 로고
    • Surface antigens of melanocytes and melanomas. Markers of melanocyte differentiation and melanoma subsets
    • Houghton A.N., Eisinger M., Albino A.P., Cairncross J.G., Old L.J. Surface antigens of melanocytes and melanomas. Markers of melanocyte differentiation and melanoma subsets. J. Exp. Med. 1982, 156:1755-1766.
    • (1982) J. Exp. Med. , vol.156 , pp. 1755-1766
    • Houghton, A.N.1    Eisinger, M.2    Albino, A.P.3    Cairncross, J.G.4    Old, L.J.5
  • 28
    • 0028245615 scopus 로고
    • Identification of a novel integrin binding site in fibronectin. Differential utilization by beta 3 integrins
    • Bowditch R.D., et al. Identification of a novel integrin binding site in fibronectin. Differential utilization by beta 3 integrins. J. Biol. Chem. 1994, 269:10856-10863.
    • (1994) J. Biol. Chem. , vol.269 , pp. 10856-10863
    • Bowditch, R.D.1
  • 29
    • 0025895086 scopus 로고
    • Integrins alpha v beta 3 and alpha v beta 5 contribute to cell attachment to vitronectin but differentially distribute on the cell surface
    • Wayner E.A., Orlando R.A., Cheresh D.A. Integrins alpha v beta 3 and alpha v beta 5 contribute to cell attachment to vitronectin but differentially distribute on the cell surface. J. Cell Biol. 1991, 113:919-929.
    • (1991) J. Cell Biol. , vol.113 , pp. 919-929
    • Wayner, E.A.1    Orlando, R.A.2    Cheresh, D.A.3
  • 30
    • 0028876461 scopus 로고
    • A new adhesion assay using buoyancy to remove non-adherent cells
    • Goodwin A.E., Pauli B.U. A new adhesion assay using buoyancy to remove non-adherent cells. J. Immunol. Methods 1995, 187:213-219.
    • (1995) J. Immunol. Methods , vol.187 , pp. 213-219
    • Goodwin, A.E.1    Pauli, B.U.2
  • 31
    • 0037077225 scopus 로고    scopus 로고
    • Unique ability of integrin alpha(v)beta 3 to support tumor cell arrest under dynamic flow conditions
    • Pilch J., Habermann R., Felding-Habermann B. Unique ability of integrin alpha(v)beta 3 to support tumor cell arrest under dynamic flow conditions. J. Biol. Chem. 2002, 277:21930-21938.
    • (2002) J. Biol. Chem. , vol.277 , pp. 21930-21938
    • Pilch, J.1    Habermann, R.2    Felding-Habermann, B.3
  • 32
    • 0031594601 scopus 로고    scopus 로고
    • Alphav integrins mediate adhesion and migration of breast carcinoma cell lines
    • Wong N.C., et al. Alphav integrins mediate adhesion and migration of breast carcinoma cell lines. Clin. Exp. Metastasis 1998, 16:50-61.
    • (1998) Clin. Exp. Metastasis , vol.16 , pp. 50-61
    • Wong, N.C.1
  • 33
    • 0032578360 scopus 로고    scopus 로고
    • The role of alpha2 beta1 and alpha3 beta1 integrin receptors in the initial anchoring of MDA-MB-231 human breast cancer cells to cortical bone matrix
    • Lundström A., Holmbom J., Lindqvist C., Nordström T. The role of alpha2 beta1 and alpha3 beta1 integrin receptors in the initial anchoring of MDA-MB-231 human breast cancer cells to cortical bone matrix. Biochem. Biophys. Res. Commun. 1998, 250:735-740.
    • (1998) Biochem. Biophys. Res. Commun. , vol.250 , pp. 735-740
    • Lundström, A.1    Holmbom, J.2    Lindqvist, C.3    Nordström, T.4
  • 34
    • 0345215170 scopus 로고    scopus 로고
    • Utilization of a soluble integrin-alkaline phosphatase chimera to characterize integrin alpha 8 beta 1 receptor interactions with tenascin: murine alpha 8 beta 1 binds to the RGD site in tenascin-C fragments, but not to native tenascin-C
    • Denda S., Müller U., Crossin K.L., Erickson H.P., Reichardt L.F. Utilization of a soluble integrin-alkaline phosphatase chimera to characterize integrin alpha 8 beta 1 receptor interactions with tenascin: murine alpha 8 beta 1 binds to the RGD site in tenascin-C fragments, but not to native tenascin-C. Biochemistry 1998, 37:5464-5474.
    • (1998) Biochemistry , vol.37 , pp. 5464-5474
    • Denda, S.1    Müller, U.2    Crossin, K.L.3    Erickson, H.P.4    Reichardt, L.F.5
  • 37
    • 84882997830 scopus 로고    scopus 로고
    • Integrin activation states and eosinophil recruitment in asthma
    • Johansson M.W., Mosher D.F. Integrin activation states and eosinophil recruitment in asthma. Front. Pharmacol. 2013, 4:33.
    • (2013) Front. Pharmacol. , vol.4 , pp. 33
    • Johansson, M.W.1    Mosher, D.F.2
  • 38
    • 0035852648 scopus 로고    scopus 로고
    • Integrin activation controls metastasis in human breast cancer
    • Felding-Habermann B., et al. Integrin activation controls metastasis in human breast cancer. Proc. Natl. Acad. Sci. U. S. A. 2001, 98:1853-1858.
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , pp. 1853-1858
    • Felding-Habermann, B.1
  • 39
    • 0023944337 scopus 로고
    • Cell-surface anchoring of proteins via glycosyl-phosphatidylinositol structures
    • Ferguson M.A., Williams A.F. Cell-surface anchoring of proteins via glycosyl-phosphatidylinositol structures. Annu. Rev. Biochem. 1988, 57:285-320.
    • (1988) Annu. Rev. Biochem. , vol.57 , pp. 285-320
    • Ferguson, M.A.1    Williams, A.F.2
  • 41
    • 85047697499 scopus 로고    scopus 로고
    • PARP-1 modifies the effectiveness of p53-mediated DNA damage response
    • Valenzuela M.T., et al. PARP-1 modifies the effectiveness of p53-mediated DNA damage response. Oncogene 2002, 21:1108-1116.
    • (2002) Oncogene , vol.21 , pp. 1108-1116
    • Valenzuela, M.T.1
  • 42
    • 0035913903 scopus 로고    scopus 로고
    • HSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase
    • Vaziri H., et al. hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase. Cell 2001, 107:149-159.
    • (2001) Cell , vol.107 , pp. 149-159
    • Vaziri, H.1
  • 43
    • 84872268055 scopus 로고    scopus 로고
    • Sirtuins: NAD(+)-dependent deacetylase mechanism and regulation
    • Sauve A.A., Youn D.Y. Sirtuins: NAD(+)-dependent deacetylase mechanism and regulation. Curr. Opin. Chem. Biol. 2012, 16:535-543.
    • (2012) Curr. Opin. Chem. Biol. , vol.16 , pp. 535-543
    • Sauve, A.A.1    Youn, D.Y.2
  • 45
    • 78650308691 scopus 로고    scopus 로고
    • Redox-dependent Brca1 transcriptional regulation by an NADH-sensor CtBP1
    • Deng Y., et al. Redox-dependent Brca1 transcriptional regulation by an NADH-sensor CtBP1. Oncogene 2010, 29:6603-6608.
    • (2010) Oncogene , vol.29 , pp. 6603-6608
    • Deng, Y.1
  • 47
    • 20444469625 scopus 로고    scopus 로고
    • Regulation of BRCA2 gene expression by the SLUG repressor protein in human breast cells
    • Tripathi M.K., et al. Regulation of BRCA2 gene expression by the SLUG repressor protein in human breast cells. J. Biol. Chem. 2005, 280:17163-17171.
    • (2005) J. Biol. Chem. , vol.280 , pp. 17163-17171
    • Tripathi, M.K.1
  • 48
    • 80052524202 scopus 로고    scopus 로고
    • High visfatin expression in breast cancer tissue is associated with poor survival
    • Lee Y.-C., et al. High visfatin expression in breast cancer tissue is associated with poor survival. Cancer Epidemiol. Biomarkers Prev. 2011, 20:1892-1901.
    • (2011) Cancer Epidemiol. Biomarkers Prev. , vol.20 , pp. 1892-1901
    • Lee, Y.-C.1
  • 50
    • 27144459430 scopus 로고    scopus 로고
    • Gene expression profile associated with response to doxorubicin-based therapy in breast cancer
    • Folgueira M.A.A.K., et al. Gene expression profile associated with response to doxorubicin-based therapy in breast cancer. Clin. Cancer Res. 2005, 11:7434-7443.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 7434-7443
    • Folgueira, M.A.A.K.1
  • 51
    • 33746563570 scopus 로고    scopus 로고
    • Integrin-mediated transcriptional activation of inhibitor of apoptosis proteins protects smooth muscle cells against apoptosis induced by degraded collagen
    • Von Wnuck Lipinski K., et al. Integrin-mediated transcriptional activation of inhibitor of apoptosis proteins protects smooth muscle cells against apoptosis induced by degraded collagen. Circ. Res. 2006, 98:1490-1497.
    • (2006) Circ. Res. , vol.98 , pp. 1490-1497
    • Von Wnuck Lipinski, K.1
  • 52
    • 34548173742 scopus 로고    scopus 로고
    • Kininostatin associates with membrane rafts and inhibits alpha(v)beta3 integrin activation in human umbilical vein endothelial cells
    • Wu Y., et al. Kininostatin associates with membrane rafts and inhibits alpha(v)beta3 integrin activation in human umbilical vein endothelial cells. Arterioscler. Thromb. Vasc. Biol. 2007, 27:1968-1975.
    • (2007) Arterioscler. Thromb. Vasc. Biol. , vol.27 , pp. 1968-1975
    • Wu, Y.1
  • 53
    • 84904258144 scopus 로고    scopus 로고
    • The receptor for urokinase-plasminogen activator (uPAR) controls plasticity of cancer cell movement in mesenchymal and amoeboid migration style
    • Margheri F., et al. The receptor for urokinase-plasminogen activator (uPAR) controls plasticity of cancer cell movement in mesenchymal and amoeboid migration style. Oncotarget 2014, 5:1538-1553.
    • (2014) Oncotarget , vol.5 , pp. 1538-1553
    • Margheri, F.1
  • 54
    • 84878548018 scopus 로고    scopus 로고
    • Intracellular NAD(H) levels control motility and invasion of glioma cells
    • Van Horssen R., et al. Intracellular NAD(H) levels control motility and invasion of glioma cells. Cell. Mol. Life Sci. 2013, 70:2175-2190.
    • (2013) Cell. Mol. Life Sci. , vol.70 , pp. 2175-2190
    • Van Horssen, R.1
  • 56
  • 57
    • 79251478398 scopus 로고    scopus 로고
    • Contribution of platelets to tumour metastasis
    • Gay L.J., Felding-Habermann B. Contribution of platelets to tumour metastasis. Nat. Rev. Cancer 2011, 11:123-134.
    • (2011) Nat. Rev. Cancer , vol.11 , pp. 123-134
    • Gay, L.J.1    Felding-Habermann, B.2
  • 58
    • 77953242479 scopus 로고    scopus 로고
    • Targeting activated integrin alphavbeta3 with patient-derived antibodies impacts late-stage multiorgan metastasis
    • Staflin K., et al. Targeting activated integrin alphavbeta3 with patient-derived antibodies impacts late-stage multiorgan metastasis. Clin. Exp. Metastasis 2010, 27:217-231.
    • (2010) Clin. Exp. Metastasis , vol.27 , pp. 217-231
    • Staflin, K.1
  • 59
    • 12744271879 scopus 로고    scopus 로고
    • ADP-ribosylation of integrin alpha7 modulates the binding of integrin alpha7beta1 to laminin
    • Zhao Z., Gruszczynska-Biegala J., Zolkiewska A. ADP-ribosylation of integrin alpha7 modulates the binding of integrin alpha7beta1 to laminin. Biochem. J. 2005, 385:309-317.
    • (2005) Biochem. J. , vol.385 , pp. 309-317
    • Zhao, Z.1    Gruszczynska-Biegala, J.2    Zolkiewska, A.3
  • 60
    • 77955443309 scopus 로고    scopus 로고
    • Nampt/PBEF/visfatin and cancer
    • Bi T., Che X. Nampt/PBEF/visfatin and cancer. Cancer Biol. Ther. 2010, 10:119-125.
    • (2010) Cancer Biol. Ther. , vol.10 , pp. 119-125
    • Bi, T.1    Che, X.2
  • 61
    • 33846527541 scopus 로고    scopus 로고
    • Visfatin, an adipocytokine with proinflammatory and immunomodulating properties
    • Moschen A.R., et al. Visfatin, an adipocytokine with proinflammatory and immunomodulating properties. J. Immunol. 2007, 178:1748-1758.
    • (2007) J. Immunol. , vol.178 , pp. 1748-1758
    • Moschen, A.R.1
  • 62
    • 84868588684 scopus 로고    scopus 로고
    • + salvage pathway induces autophagy in multiple myeloma cells via mTORC1 and extracellular signal-regulated kinase (ERK1/2) inhibition
    • + salvage pathway induces autophagy in multiple myeloma cells via mTORC1 and extracellular signal-regulated kinase (ERK1/2) inhibition. Blood 2012, 120:3519-3529.
    • (2012) Blood , vol.120 , pp. 3519-3529
    • Cea, M.1
  • 63
    • 42349084337 scopus 로고    scopus 로고
    • Visfatin induces human endothelial VEGF and MMP-2/9 production via MAPK and PI3K/Akt signalling pathways: novel insights into visfatin-induced angiogenesis
    • Adya R., Tan B.K., Punn A., Chen J., Randeva H.S. Visfatin induces human endothelial VEGF and MMP-2/9 production via MAPK and PI3K/Akt signalling pathways: novel insights into visfatin-induced angiogenesis. Cardiovasc. Res. 2008, 78:356-365.
    • (2008) Cardiovasc. Res. , vol.78 , pp. 356-365
    • Adya, R.1    Tan, B.K.2    Punn, A.3    Chen, J.4    Randeva, H.S.5
  • 64
    • 58049200121 scopus 로고    scopus 로고
    • Extracellular Nampt promotes macrophage survival via a nonenzymatic interleukin-6/STAT3 signaling mechanism
    • Li Y., et al. Extracellular Nampt promotes macrophage survival via a nonenzymatic interleukin-6/STAT3 signaling mechanism. J. Biol. Chem. 2008, 283:34833-34843.
    • (2008) J. Biol. Chem. , vol.283 , pp. 34833-34843
    • Li, Y.1
  • 65
    • 33846211375 scopus 로고    scopus 로고
    • Inflammation, cancer and chemoresistance: taking advantage of the toll-like receptor signaling pathway
    • Chen R., Alvero A.B., Silasi D.-A., Mor G. Inflammation, cancer and chemoresistance: taking advantage of the toll-like receptor signaling pathway. Am. J. Reprod. Immunol. 2007, 57:93-107.
    • (2007) Am. J. Reprod. Immunol. , vol.57 , pp. 93-107
    • Chen, R.1    Alvero, A.B.2    Silasi, D.-A.3    Mor, G.4
  • 66
    • 84860356619 scopus 로고    scopus 로고
    • Proinflammatory actions of visfatin/nicotinamide phosphoribosyltransferase (Nampt) involve regulation of insulin signaling pathway and Nampt enzymatic activity
    • Jacques C., et al. Proinflammatory actions of visfatin/nicotinamide phosphoribosyltransferase (Nampt) involve regulation of insulin signaling pathway and Nampt enzymatic activity. J. Biol. Chem. 2012, 287:15100-15108.
    • (2012) J. Biol. Chem. , vol.287 , pp. 15100-15108
    • Jacques, C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.