-
1
-
-
84855357959
-
Taste receptor signalling—From tongues to lungs
-
[CrossRef] [PubMed]
-
Kinnamon, S.C. Taste receptor signalling—From tongues to lungs. Acta Physiol. 2012, 204, 158–168. [CrossRef] [PubMed]
-
(2012)
Acta Physiol
, vol.204
, pp. 158-168
-
-
Kinnamon, S.C.1
-
2
-
-
0034677655
-
T2Rs function as bitter taste receptors
-
[CrossRef]
-
Chandrashekar, J.; Mueller, K.L.; Hoon, M.A.; Adler, E.; Feng, L.; Guo, W.; Zuker, C.S.; Ryba, N.J. T2Rs function as bitter taste receptors. Cell 2000, 100, 703–711. [CrossRef]
-
(2000)
Cell
, vol.100
, pp. 703-711
-
-
Chandrashekar, J.1
Mueller, K.L.2
Hoon, M.A.3
Adler, E.4
Feng, L.5
Guo, W.6
Zuker, C.S.7
Ryba, N.J.8
-
3
-
-
0034677653
-
A novel family of mammalian taste receptors
-
[CrossRef]
-
Adler, E.; Hoon, M.A.; Mueller, K.L.; Chandrashekar, J.; Ryba, N.J.; Zuker, C.S. A novel family of mammalian taste receptors. Cell 2000, 100, 693–702. [CrossRef]
-
(2000)
Cell
, vol.100
, pp. 693-702
-
-
Adler, E.1
Hoon, M.A.2
Mueller, K.L.3
Chandrashekar, J.4
Ryba, N.J.5
Zuker, C.S.6
-
4
-
-
0033582645
-
Putative mammalian taste receptors: A class of taste-specific gpcrs with distinct topographic selectivity
-
[CrossRef]
-
Hoon, M.A.; Adler, E.; Lindemeier, J.; Battey, J.F.; Ryba, N.J.P.; Zuker, C.S. Putative mammalian taste receptors: A class of taste-specific gpcrs with distinct topographic selectivity. Cell 1999, 96, 541–551. [CrossRef]
-
(1999)
Cell
, vol.96
, pp. 541-551
-
-
Hoon, M.A.1
Adler, E.2
Lindemeier, J.3
Battey, J.F.4
Ryba, N.J.P.5
Zuker, C.S.6
-
5
-
-
84870314938
-
Extraoral bitter taste receptors as mediators of off-target drug effects
-
[CrossRef] [PubMed]
-
Clark, A.A.; Liggett, S.B.; Munger, S.D. Extraoral bitter taste receptors as mediators of off-target drug effects. FASEB J. 2012, 26, 4827–4831. [CrossRef] [PubMed]
-
(2012)
FASEB J
, vol.26
, pp. 4827-4831
-
-
Clark, A.A.1
Liggett, S.B.2
Munger, S.D.3
-
6
-
-
84902271945
-
Functional roles of the sweet taste receptor in oral and extraoral tissues
-
[CrossRef] [PubMed]
-
Laffitte, A.; Neiers, F.; Briand, L. Functional roles of the sweet taste receptor in oral and extraoral tissues. Curr. Opin. Clin. Nutr. Metab. Care 2014, 17, 379–385. [CrossRef] [PubMed]
-
(2014)
Curr. Opin. Clin. Nutr. Metab. Care
, vol.17
, pp. 379-385
-
-
Laffitte, A.1
Neiers, F.2
Briand, L.3
-
7
-
-
84936098219
-
Tas2r bitter taste receptors regulate thyroid function
-
[CrossRef] [PubMed]
-
Clark, A.A.; Dotson, C.D.; Elson, A.E.; Voigt, A.; Boehm, U.; Meyerhof, W.; Steinle, N.I.; Munger, S.D. Tas2r bitter taste receptors regulate thyroid function. FASEB J. 2015, 29, 164–172. [CrossRef] [PubMed]
-
(2015)
FASEB J
, vol.29
, pp. 164-172
-
-
Clark, A.A.1
Dotson, C.D.2
Elson, A.E.3
Voigt, A.4
Boehm, U.5
Meyerhof, W.6
Steinle, N.I.7
Munger, S.D.8
-
8
-
-
15044353688
-
The receptors and coding logic for bitter taste
-
[CrossRef] [PubMed]
-
Mueller, K.L.; Hoon, M.A.; Erlenbach, I.; Chandrashekar, J.; Zuker, C.S.; Ryba, N.J.P. The receptors and coding logic for bitter taste. Nature 2005, 434, 225–229. [CrossRef] [PubMed]
-
(2005)
Nature
, vol.434
, pp. 225-229
-
-
Mueller, K.L.1
Hoon, M.A.2
Erlenbach, I.3
Chandrashekar, J.4
Zuker, C.S.5
Ryba, N.J.P.6
-
9
-
-
84920845080
-
Expression and functional activity of the bitter taste receptors TAS2R1 and TAS2R38 in human keratinocytes
-
[CrossRef] [PubMed]
-
Wölfle, U.; Elsholz, F.A.; Kersten, A.; Haarhaus, B.; Müller, W.E.; Schempp, C.M. Expression and functional activity of the bitter taste receptors TAS2R1 and TAS2R38 in human keratinocytes. Skin Pharmacol. Physiol. 2015, 28, 137–146. [CrossRef] [PubMed]
-
(2015)
Skin Pharmacol. Physiol
, vol.28
, pp. 137-146
-
-
Wölfle, U.1
Elsholz, F.A.2
Kersten, A.3
Haarhaus, B.4
Müller, W.E.5
Schempp, C.M.6
-
10
-
-
84871129066
-
Functional characterization of bitter-taste receptors expressed in mammalian testis
-
[CrossRef] [PubMed]
-
Xu, J.; Cao, J.; Iguchi, N.; Riethmacher, D.; Huang, L. Functional characterization of bitter-taste receptors expressed in mammalian testis. Mol. Hum. Reprod. 2013, 19, 17–28. [CrossRef] [PubMed]
-
(2013)
Mol. Hum. Reprod
, vol.19
, pp. 17-28
-
-
Xu, J.1
Cao, J.2
Iguchi, N.3
Riethmacher, D.4
Huang, L.5
-
11
-
-
84868610108
-
T2R38 taste receptor polymorphisms underlie susceptibility to upper respiratory infection
-
[CrossRef] [PubMed]
-
Lee, R.J.; Xiong, G.; Kofonow, J.M.; Chen, B.; Lysenko, A.; Jiang, P.; Abraham, V.; Doghramji, L.; Adappa, N.D.; Palmer, J.N.; et al. T2R38 taste receptor polymorphisms underlie susceptibility to upper respiratory infection. J. Clin. Investig. 2012, 122, 4145–4159. [CrossRef] [PubMed]
-
(2012)
J. Clin. Investig
, vol.122
, pp. 4145-4159
-
-
Lee, R.J.1
Xiong, G.2
Kofonow, J.M.3
Chen, B.4
Lysenko, A.5
Jiang, P.6
Abraham, V.7
Doghramji, L.8
Adappa, N.D.9
Palmer, J.N.10
-
12
-
-
69549084858
-
Motile cilia of human airway epithelia are chemosensory
-
[CrossRef] [PubMed]
-
Shah, A.S.; Ben-Shahar, Y.; Moninger, T.O.; Kline, J.N.; Welsh, M.J. Motile cilia of human airway epithelia are chemosensory. Science 2009, 325, 1131–1134. [CrossRef] [PubMed]
-
(2009)
Science
, vol.325
, pp. 1131-1134
-
-
Shah, A.S.1
Ben-Shahar, Y.2
Moninger, T.O.3
Kline, J.N.4
Welsh, M.J.5
-
13
-
-
85006725999
-
The genetics of the bitter taste receptor T2R38 in upper airway innate immunity and implications for chronic rhinosinusitis
-
[CrossRef] [PubMed]
-
Cohen, N.A. The genetics of the bitter taste receptor T2R38 in upper airway innate immunity and implications for chronic rhinosinusitis. Laryngoscope 2016, 127, 44–51. [CrossRef] [PubMed]
-
(2016)
Laryngoscope
, vol.127
, pp. 44-51
-
-
Cohen, N.A.1
-
14
-
-
84896770768
-
Bitter and sweet taste receptors regulate human upper respiratory innate immunity
-
[CrossRef] [PubMed]
-
Lee, R.J.; Kofonow, J.M.; Rosen, P.L.; Siebert, A.P.; Chen, B.; Doghramji, L.; Xiong, G.; Adappa, N.D.; Palmer, J.N.; Kennedy, D.W.; et al. Bitter and sweet taste receptors regulate human upper respiratory innate immunity. J. Clin. Investig. 2014, 124, 1393–1405. [CrossRef] [PubMed]
-
(2014)
J. Clin. Investig
, vol.124
, pp. 1393-1405
-
-
Lee, R.J.1
Kofonow, J.M.2
Rosen, P.L.3
Siebert, A.P.4
Chen, B.5
Doghramji, L.6
Xiong, G.7
Adappa, N.D.8
Palmer, J.N.9
Kennedy, D.W.10
-
15
-
-
84882909947
-
The bad taste of medicines: Overview of basic research on bitter taste
-
[CrossRef] [PubMed]
-
Mennella, J.A.; Spector, A.C.; Reed, D.R.; Coldwell, S.E. The bad taste of medicines: Overview of basic research on bitter taste. Clin. Ther. 2013, 35, 1225–1246. [CrossRef] [PubMed]
-
(2013)
Clin. Ther
, vol.35
, pp. 1225-1246
-
-
Mennella, J.A.1
Spector, A.C.2
Reed, D.R.3
Coldwell, S.E.4
-
16
-
-
84875635849
-
Oral and extra-oral taste perception
-
[CrossRef] [PubMed]
-
Yamamoto, K.; Ishimaru, Y. Oral and extra-oral taste perception. Semin. Cell Dev. Biol. 2013, 24, 240–246. [CrossRef] [PubMed]
-
(2013)
Semin. Cell Dev. Biol
, vol.24
, pp. 240-246
-
-
Yamamoto, K.1
Ishimaru, Y.2
-
17
-
-
84874956365
-
CALHM1 ion channel mediates purinergic neurotransmission of sweet, bitter and umami tastes
-
[CrossRef] [PubMed]
-
Taruno, A.; Vingtdeux, V.; Ohmoto, M.; Ma, Z.; Dvoryanchikov, G.; Li, A.; Adrien, L.; Zhao, H.; Leung, S.; Abernethy, M.; et al. CALHM1 ion channel mediates purinergic neurotransmission of sweet, bitter and umami tastes. Nature 2013, 495, 223–226. [CrossRef] [PubMed]
-
(2013)
Nature
, vol.495
, pp. 223-226
-
-
Taruno, A.1
Vingtdeux, V.2
Ohmoto, M.3
Ma, Z.4
Dvoryanchikov, G.5
Li, A.6
Adrien, L.7
Zhao, H.8
Leung, S.9
Abernethy, M.10
-
18
-
-
84920646924
-
Mendelian genetics of human susceptibility to fungal infection
-
[CrossRef] [PubMed]
-
Lionakis, M.S.; Netea, M.G.; Holland, S.M. Mendelian genetics of human susceptibility to fungal infection. Cold Spring Harb. Perspect. Med. 2014, 4, a019638. [CrossRef] [PubMed]
-
(2014)
Cold Spring Harb. Perspect. Med
, vol.4
, pp. a019638
-
-
Lionakis, M.S.1
Netea, M.G.2
Holland, S.M.3
-
19
-
-
77953892833
-
Oligomerization of TAS2R bitter taste receptors
-
[CrossRef] [PubMed]
-
Kuhn, C.; Bufe, B.; Batram, C.; Meyerhof, W. Oligomerization of TAS2R bitter taste receptors. Chem. Sens. 2010, 35, 395–406. [CrossRef] [PubMed]
-
(2010)
Chem. Sens
, vol.35
, pp. 395-406
-
-
Kuhn, C.1
Bufe, B.2
Batram, C.3
Meyerhof, W.4
-
20
-
-
13944250257
-
The molecular basis of individual differences in phenylthiocarbamide and propylthiouracil bitterness perception
-
[CrossRef] [PubMed]
-
Bufe, B.; Breslin, P.A.S.; Kuhn, C.; Reed, D.R.; Tharp, C.D.; Slack, J.P.; Kim, U.-K.; Drayna, D.; Meyerhof, W. The molecular basis of individual differences in phenylthiocarbamide and propylthiouracil bitterness perception. Curr. Biol. 2005, 15, 322–327. [CrossRef] [PubMed]
-
(2005)
Curr. Biol
, vol.15
, pp. 322-327
-
-
Bufe, B.1
Breslin, P.A.S.2
Kuhn, C.3
Reed, D.R.4
Tharp, C.D.5
Slack, J.P.6
Kim, U.-K.7
Drayna, D.8
Meyerhof, W.9
-
21
-
-
77950114281
-
The molecular receptive ranges of human TAS2R bitter taste receptors
-
[CrossRef] [PubMed]
-
Meyerhof, W.; Batram, C.; Kuhn, C.; Brockhoff, A.; Chudoba, E.; Bufe, B.; Appendino, G.; Behrens, M. The molecular receptive ranges of human TAS2R bitter taste receptors. Chem. Sens. 2010, 35, 157–170. [CrossRef] [PubMed]
-
(2010)
Chem. Sens
, vol.35
, pp. 157-170
-
-
Meyerhof, W.1
Batram, C.2
Kuhn, C.3
Brockhoff, A.4
Chudoba, E.5
Bufe, B.6
Appendino, G.7
Behrens, M.8
-
22
-
-
84884872511
-
Human bitter perception correlates with bitter receptor messenger rna expression in taste cells
-
[CrossRef] [PubMed]
-
Lipchock, S.V.; Mennella, J.A.; Spielman, A.I.; Reed, D.R. Human bitter perception correlates with bitter receptor messenger rna expression in taste cells. Am. J. Clin. Nutr. 2013, 98, 1136–1143. [CrossRef] [PubMed]
-
(2013)
Am. J. Clin. Nutr
, vol.98
, pp. 1136-1143
-
-
Lipchock, S.V.1
Mennella, J.A.2
Spielman, A.I.3
Reed, D.R.4
-
23
-
-
84891595945
-
The bitter taste receptor T2R38 is an independent risk factor for chronic rhinosinusitis requiring sinus surgery
-
[CrossRef] [PubMed]
-
Adappa, N.D.; Zhang, Z.; Palmer, J.N.; Kennedy, D.W.; Doghramji, L.; Lysenko, A.; Reed, D.R.; Scott, T.; Zhao, N.W.; Owens, D.; et al. The bitter taste receptor T2R38 is an independent risk factor for chronic rhinosinusitis requiring sinus surgery. Int. Forum Allergy Rhinol. 2014, 4, 3–7. [CrossRef] [PubMed]
-
(2014)
Int. Forum Allergy Rhinol
, vol.4
, pp. 3-7
-
-
Adappa, N.D.1
Zhang, Z.2
Palmer, J.N.3
Kennedy, D.W.4
Doghramji, L.5
Lysenko, A.6
Reed, D.R.7
Scott, T.8
Zhao, N.W.9
Owens, D.10
-
24
-
-
0035079664
-
The genetics of phenylthiocarbamide perception
-
[PubMed]
-
Guo, S.W.; Reed, D.R. The genetics of phenylthiocarbamide perception. Ann. Hum. Biol. 2001, 28, 111–142. [PubMed]
-
(2001)
Ann. Hum. Biol
, vol.28
, pp. 111-142
-
-
Guo, S.W.1
Reed, D.R.2
-
25
-
-
84880004311
-
Genetic, functional, and phenotypic diversity in TAS2R38-mediated bitter taste perception
-
[CrossRef] [PubMed]
-
Behrens, M.; Gunn, H.C.; Ramos, P.C.M.; Meyerhof, W.; Wooding, S.P. Genetic, functional, and phenotypic diversity in TAS2R38-mediated bitter taste perception. Chem. Senses 2013, 38, 475–484. [CrossRef] [PubMed]
-
(2013)
Chem. Senses
, vol.38
, pp. 475-484
-
-
Behrens, M.1
Gunn, H.C.2
Ramos, P.C.M.3
Meyerhof, W.4
Wooding, S.P.5
-
26
-
-
33748923448
-
Sinonasal mucociliary clearance in health and disease
-
[CrossRef]
-
Cohen, N.A. Sinonasal mucociliary clearance in health and disease. Ann. Otol. Rhinol. Laryngol. Suppl. 2006, 115, 20–26. [CrossRef]
-
(2006)
Ann. Otol. Rhinol. Laryngol. Suppl
, vol.115
, pp. 20-26
-
-
Cohen, N.A.1
-
27
-
-
84857734855
-
Acquired cilia dysfunction in chronic rhinosinusitis
-
[CrossRef] [PubMed]
-
Gudis, D.; Zhao, K.Q.; Cohen, N.A. Acquired cilia dysfunction in chronic rhinosinusitis. Am. J. Rhinol. Allergy 2012, 26, 1–6. [CrossRef] [PubMed]
-
(2012)
Am. J. Rhinol. Allergy
, vol.26
, pp. 1-6
-
-
Gudis, D.1
Zhao, K.Q.2
Cohen, N.A.3
-
28
-
-
70350352914
-
Epithelium, cilia, and mucus: Their importance in chronic rhinosinusitis
-
[CrossRef] [PubMed]
-
Antunes, M.B.; Gudis, D.A.; Cohen, N.A. Epithelium, cilia, and mucus: Their importance in chronic rhinosinusitis. Immunol. Allergy Clin. N. Am. 2009, 29, 631–643. [CrossRef] [PubMed]
-
(2009)
Immunol. Allergy Clin. N. Am
, vol.29
, pp. 631-643
-
-
Antunes, M.B.1
Gudis, D.A.2
Cohen, N.A.3
-
29
-
-
0014816714
-
The role of mucus in transport by cilia
-
[PubMed]
-
Eliezer, N.; Sade, J.; Silberberg, A.; Nevo, A.C. The role of mucus in transport by cilia. Am. Rev. Respir. Dis. 1970, 102, 48–52. [PubMed]
-
(1970)
Am. Rev. Respir. Dis
, vol.102
, pp. 48-52
-
-
Eliezer, N.1
Sade, J.2
Silberberg, A.3
Nevo, A.C.4
-
30
-
-
0036194724
-
Mucus clearance as a primary innate defense mechanism for mammalian airways
-
[CrossRef] [PubMed]
-
Knowles, M.R.; Boucher, R.C. Mucus clearance as a primary innate defense mechanism for mammalian airways. J. Clin. Investig. 2002, 109, 571–577. [CrossRef] [PubMed]
-
(2002)
J. Clin. Investig
, vol.109
, pp. 571-577
-
-
Knowles, M.R.1
Boucher, R.C.2
-
31
-
-
84860539275
-
The multiple signaling systems regulating virulence in Pseudomonas aeruginosa
-
[CrossRef] [PubMed]
-
Jimenez, P.N.; Koch, G.; Thompson, J.A.; Xavier, K.B.; Cool, R.H.; Quax, W.J. The multiple signaling systems regulating virulence in Pseudomonas aeruginosa. Microbiol. Mol. Biol. Rev. 2012, 76, 46–65. [CrossRef] [PubMed]
-
(2012)
Microbiol. Mol. Biol. Rev
, vol.76
, pp. 46-65
-
-
Jimenez, P.N.1
Koch, G.2
Thompson, J.A.3
Xavier, K.B.4
Cool, R.H.5
Quax, W.J.6
-
32
-
-
84987842258
-
Fungal aflatoxins reduce respiratory mucosal ciliary function
-
[CrossRef] [PubMed]
-
Lee, R.J.; Workman, A.D.; Carey, R.M.; Chen, B.; Rosen, P.L.; Doghramji, L.; Adappa, N.D.; Palmer, J.N.; Kennedy, D.W.; Cohen, N.A. Fungal aflatoxins reduce respiratory mucosal ciliary function. Sci. Rep. 2016, 6, 33221. [CrossRef] [PubMed]
-
(2016)
Sci. Rep
, vol.6
, pp. 33221
-
-
Lee, R.J.1
Workman, A.D.2
Carey, R.M.3
Chen, B.4
Rosen, P.L.5
Doghramji, L.6
Adappa, N.D.7
Palmer, J.N.8
Kennedy, D.W.9
Cohen, N.A.10
-
33
-
-
0019890088
-
Structural identification of autoinducer of photobacterium fischeri luciferase
-
[CrossRef] [PubMed]
-
Eberhard, A.; Burlingame, A.L.; Eberhard, C.; Kenyon, G.L.; Nealson, K.H.; Oppenheimer, N.J. Structural identification of autoinducer of photobacterium fischeri luciferase. Biochemistry 1981, 20, 2444–2449. [CrossRef] [PubMed]
-
(1981)
Biochemistry
, vol.20
, pp. 2444-2449
-
-
Eberhard, A.1
Burlingame, A.L.2
Eberhard, C.3
Kenyon, G.L.4
Nealson, K.H.5
Oppenheimer, N.J.6
-
34
-
-
79751509768
-
Microbial linguistics: Perspectives and applications of microbial cell-to-cell communication
-
[CrossRef] [PubMed]
-
Mitchell, R.J.; Lee, S.K.; Kim, T.; Ghim, C.M. Microbial linguistics: Perspectives and applications of microbial cell-to-cell communication. BMB Rep. 2011, 44, 1–10. [CrossRef] [PubMed]
-
(2011)
BMB Rep
, vol.44
, pp. 1-10
-
-
Mitchell, R.J.1
Lee, S.K.2
Kim, T.3
Ghim, C.M.4
-
35
-
-
0033591467
-
Bacterial biofilms: A common cause of persistent infections
-
[CrossRef] [PubMed]
-
Costerton, J.W.; Stewart, P.S.; Greenberg, E.P. Bacterial biofilms: A common cause of persistent infections. Science 1999, 284, 1318–1322. [CrossRef] [PubMed]
-
(1999)
Science
, vol.284
, pp. 1318-1322
-
-
Costerton, J.W.1
Stewart, P.S.2
Greenberg, E.P.3
-
36
-
-
27944501527
-
Demonstration of biofilm in human bacterial chronic rhinosinusitis
-
[PubMed]
-
Ferguson, B.J.; Stolz, D.B. Demonstration of biofilm in human bacterial chronic rhinosinusitis. Am. J. Rhinol. 2005, 19, 452–457. [PubMed]
-
(2005)
Am. J. Rhinol
, vol.19
, pp. 452-457
-
-
Ferguson, B.J.1
Stolz, D.B.2
-
37
-
-
33646795659
-
Biofilm formation by Staphylococcus aureus and Pseudomonas aeruginosa is associated with an unfavorable evolution after surgery for chronic sinusitis and nasal polyposis
-
[CrossRef] [PubMed]
-
Bendouah, Z.; Barbeau, J.; Hamad, W.A.; Desrosiers, M. Biofilm formation by Staphylococcus aureus and Pseudomonas aeruginosa is associated with an unfavorable evolution after surgery for chronic sinusitis and nasal polyposis. Otolaryngol. Head Neck Surg. 2006, 134, 991–996. [CrossRef] [PubMed]
-
(2006)
Otolaryngol. Head Neck Surg
, vol.134
, pp. 991-996
-
-
Bendouah, Z.1
Barbeau, J.2
Hamad, W.A.3
Desrosiers, M.4
-
38
-
-
77649260272
-
Nasal chemosensory cells use bitter taste signaling to detect irritants and bacterial signals
-
[CrossRef] [PubMed]
-
Tizzano, M.; Gulbransen, B.D.; Vandenbeuch, A.; Clapp, T.R.; Herman, J.P.; Sibhatu, H.M.; Churchill, M.E.A.; Silver, W.L.; Kinnamon, S.C.; Finger, T.E. Nasal chemosensory cells use bitter taste signaling to detect irritants and bacterial signals. Proc. Natl. Acad. Sci. USA 2010, 107, 3210–3215. [CrossRef] [PubMed]
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 3210-3215
-
-
Tizzano, M.1
Gulbransen, B.D.2
Vandenbeuch, A.3
Clapp, T.R.4
Herman, J.P.5
Sibhatu, H.M.6
Churchill, M.E.A.7
Silver, W.L.8
Kinnamon, S.C.9
Finger, T.E.10
-
39
-
-
34347253610
-
A comparison of experimental methods in molecular chronic rhinosinusitis research
-
[CrossRef] [PubMed]
-
Ramanathan, M., Jr.; Lane, A.P. A comparison of experimental methods in molecular chronic rhinosinusitis research. Am. J. Rhinol. 2007, 21, 373–377. [CrossRef] [PubMed]
-
(2007)
Am. J. Rhinol
, vol.21
, pp. 373-377
-
-
Ramanathan, M.1
Lane, A.P.2
-
40
-
-
9944256233
-
The use of human nasal in vitro cell systems during drug discovery and development
-
[CrossRef] [PubMed]
-
Dimova, S.; Brewster, M.E.; Noppe, M.; Jorissen, M.; Augustijns, P. The use of human nasal in vitro cell systems during drug discovery and development. Toxicol. In Vitro 2005, 19, 107–122. [CrossRef] [PubMed]
-
(2005)
Toxicol. In Vitro
, vol.19
, pp. 107-122
-
-
Dimova, S.1
Brewster, M.E.2
Noppe, M.3
Jorissen, M.4
Augustijns, P.5
-
41
-
-
84907058830
-
Mouse nasal epithelial innate immune responses to Pseudomonas aeruginosa quorum-sensing molecules require taste signaling components
-
[CrossRef] [PubMed]
-
Lee, R.J.; Chen, B.; Redding, K.M.; Margolskee, R.F.; Cohen, N.A. Mouse nasal epithelial innate immune responses to Pseudomonas aeruginosa quorum-sensing molecules require taste signaling components. Innate Immun. 2013, 20, 606–617. [CrossRef] [PubMed]
-
(2013)
Innate Immun
, vol.20
, pp. 606-617
-
-
Lee, R.J.1
Chen, B.2
Redding, K.M.3
Margolskee, R.F.4
Cohen, N.A.5
-
42
-
-
0031570501
-
Perspectives series: Host/pathogen interactions. Mechanisms of nitric oxide-related antimicrobial activity
-
[CrossRef] [PubMed]
-
Fang, F.C. Perspectives series: Host/pathogen interactions. Mechanisms of nitric oxide-related antimicrobial activity. J. Clin. Investig. 1997, 99, 2818–2825. [CrossRef] [PubMed]
-
(1997)
J. Clin. Investig
, vol.99
, pp. 2818-2825
-
-
Fang, F.C.1
-
43
-
-
0030739789
-
Nitric oxide and antimicrobial activity of reactive oxygen intermediates
-
[CrossRef]
-
Marcinkiewicz, J. Nitric oxide and antimicrobial activity of reactive oxygen intermediates. Immunopharmacology 1997, 37, 35–41. [CrossRef]
-
(1997)
Immunopharmacology
, vol.37
, pp. 35-41
-
-
Marcinkiewicz, J.1
-
44
-
-
77956231162
-
Antimicrobial properties of nitric oxide and its application in antimicrobial formulations and medical devices
-
[CrossRef] [PubMed]
-
Jones, M.L.; Ganopolsky, J.G.; Labbé, A.; Wahl, C.; Prakash, S. Antimicrobial properties of nitric oxide and its application in antimicrobial formulations and medical devices. Appl. Microbiol. Biotechnol. 2010, 88, 401–407. [CrossRef] [PubMed]
-
(2010)
Appl. Microbiol. Biotechnol
, vol.88
, pp. 401-407
-
-
Jones, M.L.1
Ganopolsky, J.G.2
Labbé, A.3
Wahl, C.4
Prakash, S.5
-
45
-
-
84862852281
-
The potential of nitric oxide releasing therapies as antimicrobial agents
-
[CrossRef] [PubMed]
-
Schairer, D.O.; Chouake, J.S.; Nosanchuk, J.D.; Friedman, A.J. The potential of nitric oxide releasing therapies as antimicrobial agents. Virulence 2012, 3, 271–279. [CrossRef] [PubMed]
-
(2012)
Virulence
, vol.3
, pp. 271-279
-
-
Schairer, D.O.1
Chouake, J.S.2
Nosanchuk, J.D.3
Friedman, A.J.4
-
46
-
-
33947367829
-
Regulation of mammalian ciliary beating
-
[CrossRef] [PubMed]
-
Salathe, M. Regulation of mammalian ciliary beating. Annu. Rev. Physiol. 2007, 69, 401–422. [CrossRef] [PubMed]
-
(2007)
Annu. Rev. Physiol
, vol.69
, pp. 401-422
-
-
Salathe, M.1
-
47
-
-
0027291291
-
Modulation of airway epithelial cell ciliary beat frequency by nitric oxide
-
[CrossRef] [PubMed]
-
Jain, B.; Rubinstein, I.; Robbins, R.A.; Leise, K.L.; Sisson, J.H. Modulation of airway epithelial cell ciliary beat frequency by nitric oxide. Biochem. Biophys. Res. Commun. 1993, 191, 83–88. [CrossRef] [PubMed]
-
(1993)
Biochem. Biophys. Res. Commun
, vol.191
, pp. 83-88
-
-
Jain, B.1
Rubinstein, I.2
Robbins, R.A.3
Leise, K.L.4
Sisson, J.H.5
-
48
-
-
0038650737
-
Making sense with trp channels: Store-operated calcium entry and the ion channel TRPM5 in taste receptor cells
-
[CrossRef]
-
Perez, C.A.; Margolskee, R.F.; Kinnamon, S.C.; Ogura, T. Making sense with trp channels: Store-operated calcium entry and the ion channel TRPM5 in taste receptor cells. Cell Calcium 2003, 33, 541–549. [CrossRef]
-
(2003)
Cell Calcium
, vol.33
, pp. 541-549
-
-
Perez, C.A.1
Margolskee, R.F.2
Kinnamon, S.C.3
Ogura, T.4
-
49
-
-
84871889643
-
Chemosensors in the nose: Guardians of the airways
-
[CrossRef] [PubMed]
-
Tizzano, M.; Finger, T.E. Chemosensors in the nose: Guardians of the airways. Physiology 2013, 28, 51–60. [CrossRef] [PubMed]
-
(2013)
Physiology
, vol.28
, pp. 51-60
-
-
Tizzano, M.1
Finger, T.E.2
-
50
-
-
84899050450
-
Cholinergic neurotransmission links solitary chemosensory cells to nasal inflammation
-
[CrossRef] [PubMed]
-
Saunders, C.J.; Christensen, M.; Finger, T.E.; Tizzano, M. Cholinergic neurotransmission links solitary chemosensory cells to nasal inflammation. Proc. Natl. Acad. Sci. USA 2014, 111, 6075–6080. [CrossRef] [PubMed]
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. 6075-6080
-
-
Saunders, C.J.1
Christensen, M.2
Finger, T.E.3
Tizzano, M.4
-
51
-
-
59849094422
-
Glucose homeostasis across human airway epithelial cell monolayers: Role of diffusion, transport and metabolism
-
[CrossRef] [PubMed]
-
Kalsi, K.K.; Baker, E.H.; Fraser, O.; Chung, Y.L.; Mace, O.J.; Tarelli, E.; Philips, B.J.; Baines, D.L. Glucose homeostasis across human airway epithelial cell monolayers: Role of diffusion, transport and metabolism. Pflug. Arch. 2009, 457, 1061–1070. [CrossRef] [PubMed]
-
(2009)
Pflug. Arch
, vol.457
, pp. 1061-1070
-
-
Kalsi, K.K.1
Baker, E.H.2
Fraser, O.3
Chung, Y.L.4
Mace, O.J.5
Tarelli, E.6
Philips, B.J.7
Baines, D.L.8
-
52
-
-
17644389240
-
Lactisole interacts with the transmembrane domains of human T1R3 to inhibit sweet taste
-
[CrossRef] [PubMed]
-
Jiang, P.; Cui, M.; Zhao, B.; Liu, Z.; Snyder, L.A.; Benard, L.M.; Osman, R.; Margolskee, R.F.; Max, M. Lactisole interacts with the transmembrane domains of human T1R3 to inhibit sweet taste. J. Biol. Chem. 2005, 280, 15238–15246. [CrossRef] [PubMed]
-
(2005)
J. Biol. Chem
, vol.280
, pp. 15238-15246
-
-
Jiang, P.1
Cui, M.2
Zhao, B.3
Liu, Z.4
Snyder, L.A.5
Benard, L.M.6
Osman, R.7
Margolskee, R.F.8
Max, M.9
-
53
-
-
26644458124
-
Identification of the cyclamate interaction site within the transmembrane domain of the human sweet taste receptor subunit T1R3
-
[CrossRef] [PubMed]
-
Jiang, P.; Cui, M.; Zhao, B.; Snyder, L.A.; Benard, L.M.; Osman, R.; Max, M.; Margolskee, R.F. Identification of the cyclamate interaction site within the transmembrane domain of the human sweet taste receptor subunit T1R3. J. Biol. Chem. 2005, 280, 34296–34305. [CrossRef] [PubMed]
-
(2005)
J. Biol. Chem
, vol.280
, pp. 34296-34305
-
-
Jiang, P.1
Cui, M.2
Zhao, B.3
Snyder, L.A.4
Benard, L.M.5
Osman, R.6
Max, M.7
Margolskee, R.F.8
-
54
-
-
84868513768
-
Sweet talk: Insights into the nature and importance of glucose transport in lung epithelium
-
[CrossRef] [PubMed]
-
Garnett, J.P.; Baker, E.H.; Baines, D.L. Sweet talk: Insights into the nature and importance of glucose transport in lung epithelium. Eur. Respir. J. 2012, 40, 1269–1276. [CrossRef] [PubMed]
-
(2012)
Eur. Respir. J
, vol.40
, pp. 1269-1276
-
-
Garnett, J.P.1
Baker, E.H.2
Baines, D.L.3
-
56
-
-
84897379111
-
The effect of diabetes mellitus on chronic rhinosinusitis and sinus surgery outcome
-
[CrossRef] [PubMed]
-
Zhang, Z.; Adappa, N.D.; Lautenbach, E.; Chiu, A.G.; Doghramji, L.; Howland, T.J.; Cohen, N.A.; Palmer, J.N. The effect of diabetes mellitus on chronic rhinosinusitis and sinus surgery outcome. Int. Forum Allergy Rhinol. 2014, 4, 315–320. [CrossRef] [PubMed]
-
(2014)
Int. Forum Allergy Rhinol
, vol.4
, pp. 315-320
-
-
Zhang, Z.1
Adappa, N.D.2
Lautenbach, E.3
Chiu, A.G.4
Doghramji, L.5
Howland, T.J.6
Cohen, N.A.7
Palmer, J.N.8
-
57
-
-
0029059455
-
The health impact of chronic sinusitis in patients seeking otolaryngologic care
-
[CrossRef]
-
Gliklich, R.E.; Metson, R. The health impact of chronic sinusitis in patients seeking otolaryngologic care. Otolaryngol. Head Neck Surg. 1995, 113, 104–109. [CrossRef]
-
(1995)
Otolaryngol. Head Neck Surg
, vol.113
, pp. 104-109
-
-
Gliklich, R.E.1
Metson, R.2
-
58
-
-
70349513480
-
Psychometric validity of the 22-item sinonasal outcome test
-
[CrossRef] [PubMed]
-
Hopkins, C.; Gillett, S.; Slack, R.; Lund, V.J.; Browne, J.P. Psychometric validity of the 22-item sinonasal outcome test. Clin. Otolaryngol. 2009, 34, 447–454. [CrossRef] [PubMed]
-
(2009)
Clin. Otolaryngol
, vol.34
, pp. 447-454
-
-
Hopkins, C.1
Gillett, S.2
Slack, R.3
Lund, V.J.4
Browne, J.P.5
-
59
-
-
84875042411
-
Genetics of the taste receptor T2R38 correlates with chronic rhinosinusitis necessitating surgical intervention
-
[CrossRef] [PubMed]
-
Adappa, N.D.; Howland, T.J.; Palmer, J.N.; Kennedy, D.W.; Doghramji, L.; Lysenko, A.; Reed, D.R.; Lee, R.J.; Cohen, N.A. Genetics of the taste receptor T2R38 correlates with chronic rhinosinusitis necessitating surgical intervention. Int. Forum Allergy Rhinol. 2013, 3, 184–187. [CrossRef] [PubMed]
-
(2013)
Int. Forum Allergy Rhinol
, vol.3
, pp. 184-187
-
-
Adappa, N.D.1
Howland, T.J.2
Palmer, J.N.3
Kennedy, D.W.4
Doghramji, L.5
Lysenko, A.6
Reed, D.R.7
Lee, R.J.8
Cohen, N.A.9
-
60
-
-
84953786087
-
TAS2R38 genotype predicts surgical outcome in nonpolypoid chronic rhinosinusitis
-
[CrossRef] [PubMed]
-
Adappa, N.D.; Farquhar, D.; Palmer, J.N.; Kennedy, D.W.; Doghramji, L.; Morris, S.A.; Owens, D.; Mansfield, C.; Lysenko, A.; Lee, R.J.; et al. TAS2R38 genotype predicts surgical outcome in nonpolypoid chronic rhinosinusitis. Int. Forum Allergy Rhinol. 2016, 6, 25–33. [CrossRef] [PubMed]
-
(2016)
Int. Forum Allergy Rhinol
, vol.6
, pp. 25-33
-
-
Adappa, N.D.1
Farquhar, D.2
Palmer, J.N.3
Kennedy, D.W.4
Doghramji, L.5
Morris, S.A.6
Owens, D.7
Mansfield, C.8
Lysenko, A.9
Lee, R.J.10
-
61
-
-
84895452125
-
Genetic variations in taste receptors are associated with chronic rhinosinusitis: A replication study
-
[CrossRef] [PubMed]
-
Mfuna Endam, L.; Filali-Mouhim, A.; Boisvert, P.; Boulet, L.P.; Bosse, Y.; Desrosiers, M. Genetic variations in taste receptors are associated with chronic rhinosinusitis: A replication study. Int. Forum Allergy Rhinol. 2014, 4, 200–206. [CrossRef] [PubMed]
-
(2014)
Int. Forum Allergy Rhinol
, vol.4
, pp. 200-206
-
-
Mfuna Endam, L.1
Filali-Mouhim, A.2
Boisvert, P.3
Boulet, L.P.4
Bosse, Y.5
Desrosiers, M.6
-
62
-
-
84994681089
-
The correlation of TAS2R38 gene variants with higher risk for chronic rhinosinusitis in polish patients
-
[CrossRef] [PubMed]
-
Dżaman, K.; Zagor, M.; Sarnowska, E.; Krzeski, A.; Kantor, I. The correlation of TAS2R38 gene variants with higher risk for chronic rhinosinusitis in polish patients. Otolaryngol. Pol. 2016, 70, 13–18. [CrossRef] [PubMed]
-
(2016)
Otolaryngol. Pol
, vol.70
, pp. 13-18
-
-
Dżaman, K.1
Zagor, M.2
Sarnowska, E.3
Krzeski, A.4
Kantor, I.5
-
63
-
-
84991783869
-
TAS2R38 taste receptor gene and chronic rhinosinusitis: New data from an Italian population
-
[CrossRef] [PubMed]
-
Gallo, S.; Grossi, S.; Montrasio, G.; Binelli, G.; Cinquetti, R.; Simmen, D.; Castelnuovo, P.; Campomenosi, P. TAS2R38 taste receptor gene and chronic rhinosinusitis: New data from an Italian population. BMC Med. Genet. 2016, 17, 54. [CrossRef] [PubMed]
-
(2016)
BMC Med. Genet
, vol.17
, pp. 54
-
-
Gallo, S.1
Grossi, S.2
Montrasio, G.3
Binelli, G.4
Cinquetti, R.5
Simmen, D.6
Castelnuovo, P.7
Campomenosi, P.8
-
64
-
-
84933499734
-
Comparison of radiographic and clinical characteristics of low-risk and high-risk cystic fibrosis genotypes
-
[CrossRef] [PubMed]
-
Ferril, G.R.; Nick, J.A.; Getz, A.E.; Barham, H.P.; Saavedra, M.T.; Taylor-Cousar, J.L.; Nichols, D.P.; Curran-Everett, D.; Kingdom, T.T.; Ramakrishnan, V.R. Comparison of radiographic and clinical characteristics of low-risk and high-risk cystic fibrosis genotypes. Int. Forum Allergy Rhinol. 2014, 4, 915–920. [CrossRef] [PubMed]
-
(2014)
Int. Forum Allergy Rhinol
, vol.4
, pp. 915-920
-
-
Ferril, G.R.1
Nick, J.A.2
Getz, A.E.3
Barham, H.P.4
Saavedra, M.T.5
Taylor-Cousar, J.L.6
Nichols, D.P.7
Curran-Everett, D.8
Kingdom, T.T.9
Ramakrishnan, V.R.10
-
65
-
-
0026019534
-
Severity of cystic fibrosis in patients homozygous and heterozygous for ∆F508 mutation
-
[CrossRef]
-
Johansen, H.K.; Nir, M.; Høiby, N.; Koch, C.; Schwartz, M. Severity of cystic fibrosis in patients homozygous and heterozygous for ∆F508 mutation. Lancet 1991, 337, 631–634. [CrossRef]
-
(1991)
Lancet
, vol.337
, pp. 631-634
-
-
Johansen, H.K.1
Nir, M.2
Høiby, N.3
Koch, C.4
Schwartz, M.5
-
66
-
-
0032963915
-
Genotype-phenotype correlations for the paranasal sinuses in cystic fibrosis
-
[CrossRef] [PubMed]
-
Jorissen, M.B.; de Boeck, K.; Cuppens, H. Genotype-phenotype correlations for the paranasal sinuses in cystic fibrosis. Am. J. Respir. Crit. Care Med. 1999, 159, 1412–1416. [CrossRef] [PubMed]
-
(1999)
Am. J. Respir. Crit. Care Med
, vol.159
, pp. 1412-1416
-
-
Jorissen, M.B.1
de Boeck, K.2
Cuppens, H.3
-
67
-
-
0026760116
-
Impact of sinusitis in cystic fibrosis
-
[CrossRef]
-
Ramsey, B.; Richardson, M.A. Impact of sinusitis in cystic fibrosis. J. Allergy Clin. Immunol. 1992, 90, 547–552. [CrossRef]
-
(1992)
J. Allergy Clin. Immunol
, vol.90
, pp. 547-552
-
-
Ramsey, B.1
Richardson, M.A.2
-
68
-
-
0030637676
-
Management of sinusitis in adult cystic fibrosis
-
[CrossRef] [PubMed]
-
Marks, S.C.; Kissner, D.G. Management of sinusitis in adult cystic fibrosis. Am. J. Rhinol. 1997, 11, 11–14. [CrossRef] [PubMed]
-
(1997)
Am. J. Rhinol
, vol.11
, pp. 11-14
-
-
Marks, S.C.1
Kissner, D.G.2
-
69
-
-
67249105561
-
Management of chronic rhinosinusitis in CF
-
[CrossRef]
-
Mainz, J.G.; Koitschev, A. Management of chronic rhinosinusitis in CF. J. Cyst. Fibros. 2009, 8, S10–S14. [CrossRef]
-
(2009)
J. Cyst. Fibros
, vol.8
, pp. S10-S14
-
-
Mainz, J.G.1
Koitschev, A.2
-
70
-
-
84951755876
-
T2R38 genotype is correlated with sinonasal quality of life in homozygous ∆F508 cystic fibrosis patients
-
[CrossRef] [PubMed]
-
Adappa, N.D.; Workman, A.D.; Hadjiliadis, D.; Dorgan, D.J.; Frame, D.; Brooks, S.; Doghramji, L.; Palmer, J.N.; Mansfield, C.; Reed, D.R.; et al. T2R38 genotype is correlated with sinonasal quality of life in homozygous ∆F508 cystic fibrosis patients. Int. Forum Allergy Rhinol. 2016, 6, 356–361. [CrossRef] [PubMed]
-
(2016)
Int. Forum Allergy Rhinol
, vol.6
, pp. 356-361
-
-
Adappa, N.D.1
Workman, A.D.2
Hadjiliadis, D.3
Dorgan, D.J.4
Frame, D.5
Brooks, S.6
Doghramji, L.7
Palmer, J.N.8
Mansfield, C.9
Reed, D.R.10
-
71
-
-
78650181025
-
Pseudomonas aeruginosa biofilms in cystic fibrosis
-
[CrossRef] [PubMed]
-
Høiby, N.; Ciofu, O.; Bjarnsholt, T. Pseudomonas aeruginosa biofilms in cystic fibrosis. Future Microbiol. 2010, 5, 1663–1674. [CrossRef] [PubMed]
-
(2010)
Future Microbiol
, vol.5
, pp. 1663-1674
-
-
Høiby, N.1
Ciofu, O.2
Bjarnsholt, T.3
-
72
-
-
84980332255
-
Correlation of T2R38 taste phenotype and in vitro biofilm formation from nonpolypoid chronic rhinosinusitis patients
-
[CrossRef] [PubMed]
-
Adappa, N.D.; Truesdale, C.M.; Workman, A.D.; Doghramji, L.; Mansfield, C.; Kennedy, D.W.; Palmer, J.N.; Cowart, B.J.; Cohen, N.A. Correlation of T2R38 taste phenotype and in vitro biofilm formation from nonpolypoid chronic rhinosinusitis patients. Int. Forum Allergy Rhinol. 2016, 6, 783–791. [CrossRef] [PubMed]
-
(2016)
Int. Forum Allergy Rhinol
, vol.6
, pp. 783-791
-
-
Adappa, N.D.1
Truesdale, C.M.2
Workman, A.D.3
Doghramji, L.4
Mansfield, C.5
Kennedy, D.W.6
Palmer, J.N.7
Cowart, B.J.8
Cohen, N.A.9
-
73
-
-
85122319909
-
Large scale gene expression profiling reveals distinct type 2 inflammatory patterns in chronic rhinosinusitis subtypes
-
[CrossRef] [PubMed]
-
Tyler, M.A.; Russell, C.B.; Smith, D.E.; Rottman, J.B.; Padro Dietz, C.J.; Hu, X.; Citardi, M.J.; Fakhri, S.; Assassi, S.; Luong, A. Large scale gene expression profiling reveals distinct type 2 inflammatory patterns in chronic rhinosinusitis subtypes. J. Allergy Clin. Immunol. 2016. [CrossRef] [PubMed]
-
(2016)
J. Allergy Clin. Immunol
-
-
Tyler, M.A.1
Russell, C.B.2
Smith, D.E.3
Rottman, J.B.4
Padro Dietz, C.J.5
Hu, X.6
Citardi, M.J.7
Fakhri, S.8
Assassi, S.9
Luong, A.10
-
74
-
-
79955443509
-
Pathogen yield and antimicrobial resistance patterns of chronic rhinosinusitis patients presenting to a tertiary rhinology centre
-
[PubMed]
-
Genoway, K.A.; Philpott, C.M.; Javer, A.R. Pathogen yield and antimicrobial resistance patterns of chronic rhinosinusitis patients presenting to a tertiary rhinology centre. J. Otolaryngol. Head Neck Surg. 2011, 40, 232–237. [PubMed]
-
(2011)
J. Otolaryngol. Head Neck Surg
, vol.40
, pp. 232-237
-
-
Genoway, K.A.1
Philpott, C.M.2
Javer, A.R.3
-
75
-
-
84940787490
-
Staphylococcus aureus triggers nitric oxide production in human upper airway epithelium
-
[CrossRef] [PubMed]
-
Carey, R.M.; Workman, A.D.; Chen, B.; Adappa, N.D.; Palmer, J.N.; Kennedy, D.W.; Lee, R.J.; Cohen, N.A. Staphylococcus aureus triggers nitric oxide production in human upper airway epithelium. Int. Forum Allergy Rhinol. 2015, 5, 808–813. [CrossRef] [PubMed]
-
(2015)
Int. Forum Allergy Rhinol
, vol.5
, pp. 808-813
-
-
Carey, R.M.1
Workman, A.D.2
Chen, B.3
Adappa, N.D.4
Palmer, J.N.5
Kennedy, D.W.6
Lee, R.J.7
Cohen, N.A.8
-
76
-
-
84943564180
-
Receptor polymorphism and genomic structure interact to shape bitter taste perception
-
[CrossRef] [PubMed]
-
Roudnitzky, N.; Behrens, M.; Engel, A.; Kohl, S.; Thalmann, S.; Hübner, S.; Lossow, K.; Wooding, S.P.; Meyerhof, W. Receptor polymorphism and genomic structure interact to shape bitter taste perception. PLoS Genet. 2015, 11, e1005530. [CrossRef] [PubMed]
-
(2015)
PLoS Genet
, vol.11
, pp. e1005530
-
-
Roudnitzky, N.1
Behrens, M.2
Engel, A.3
Kohl, S.4
Thalmann, S.5
Hübner, S.6
Lossow, K.7
Wooding, S.P.8
Meyerhof, W.9
|