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Volumn 87, Issue 3, 2017, Pages 221-227

IL-17 for therapy

Author keywords

Autoimmunity; IL 17; IL 17 neutralizing monoclonal antibodies; IL 17 receptor; Psoriasis

Indexed keywords

ADALIMUMAB; ADAMTS LIKE PROTEIN 5; ADAMTS PROTEIN; BRODALUMAB; COSYNTEX; ETANERCEPT; INTERLEUKIN 17; INTERLEUKIN 17F; INTERLEUKIN 23; IXEKIZUMAB; SECUKINUMAB; TALZ; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; IL17A PROTEIN, HUMAN; IL17A PROTEIN, MOUSE; MONOCLONAL ANTIBODY;

EID: 85020518169     PISSN: 09231811     EISSN: 1873569X     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2017.06.010     Document Type: Review
Times cited : (47)

References (102)
  • 1
    • 0027215897 scopus 로고
    • CTLA-8, cloned from an activated T cell, bearing AU-rich messenger RNA instability sequences, and homologous to a herpesvirus saimiri gene
    • Rouvier, E., Luciani, M.F., Mattei, M.G., Denizot, F., Golstein, P., CTLA-8, cloned from an activated T cell, bearing AU-rich messenger RNA instability sequences, and homologous to a herpesvirus saimiri gene. J. Immunol. 150:12 (1993), 5445–5456.
    • (1993) J. Immunol. , vol.150 , Issue.12 , pp. 5445-5456
    • Rouvier, E.1    Luciani, M.F.2    Mattei, M.G.3    Denizot, F.4    Golstein, P.5
  • 3
    • 80053600391 scopus 로고    scopus 로고
    • Recent advances in the IL-17 cytokine family
    • Gaffen, S.L., Recent advances in the IL-17 cytokine family. Curr. Opin. Immunol. 23:5 (2011), 613–619.
    • (2011) Curr. Opin. Immunol. , vol.23 , Issue.5 , pp. 613-619
    • Gaffen, S.L.1
  • 5
    • 70449718758 scopus 로고    scopus 로고
    • Structural basis of receptor sharing by interleukin 17 cytokines
    • Ely, L.K., Fischer, S., Garcia, K.C., Structural basis of receptor sharing by interleukin 17 cytokines. Nat. Immunol. 10:12 (2009), 1245–1251.
    • (2009) Nat. Immunol. , vol.10 , Issue.12 , pp. 1245-1251
    • Ely, L.K.1    Fischer, S.2    Garcia, K.C.3
  • 7
    • 33749138039 scopus 로고    scopus 로고
    • IL-17 production is dominated by gammadelta T cells rather than CD4T cells during Mycobacterium tuberculosis infection
    • Lockhart, E., Green, A.M., Flynn, J.L., IL-17 production is dominated by gammadelta T cells rather than CD4T cells during Mycobacterium tuberculosis infection. J. Immunol. 177:7 (2006), 4662–4669.
    • (2006) J. Immunol. , vol.177 , Issue.7 , pp. 4662-4669
    • Lockhart, E.1    Green, A.M.2    Flynn, J.L.3
  • 10
    • 42649110747 scopus 로고    scopus 로고
    • Cutting edge: NKT cells constitutively express IL-23 receptor and RORgammat and rapidly produce IL-17 upon receptor ligation in an IL-6-independent fashion
    • Rachitskaya, A.V., Hansen, A.M., Horai, R., Li, Z., Villasmil, R., Luger, D., Nussenblatt, R.B., Caspi, R.R., Cutting edge: NKT cells constitutively express IL-23 receptor and RORgammat and rapidly produce IL-17 upon receptor ligation in an IL-6-independent fashion. J. Immunol. 180:8 (2008), 5167–5171.
    • (2008) J. Immunol. , vol.180 , Issue.8 , pp. 5167-5171
    • Rachitskaya, A.V.1    Hansen, A.M.2    Horai, R.3    Li, Z.4    Villasmil, R.5    Luger, D.6    Nussenblatt, R.B.7    Caspi, R.R.8
  • 12
    • 84892827750 scopus 로고    scopus 로고
    • Activation of neutrophils by autocrine IL-17A-IL-17RC interactions during fungal infection is regulated by IL-6, IL-23, RORgammat and dectin-2
    • Taylor, P.R., Roy, S., Leal, S.M. Jr., Sun, Y., Howell, S.J., Cobb, B.A., Li, X., Pearlman, E., Activation of neutrophils by autocrine IL-17A-IL-17RC interactions during fungal infection is regulated by IL-6, IL-23, RORgammat and dectin-2. Nat. Immunol. 15:2 (2014), 143–151.
    • (2014) Nat. Immunol. , vol.15 , Issue.2 , pp. 143-151
    • Taylor, P.R.1    Roy, S.2    Leal, S.M.3    Sun, Y.4    Howell, S.J.5    Cobb, B.A.6    Li, X.7    Pearlman, E.8
  • 13
    • 34248574863 scopus 로고    scopus 로고
    • A novel heterodimeric cytokine consisting of IL-17 and IL-17F regulates inflammatory responses
    • Chang, S.H., Dong, C., A novel heterodimeric cytokine consisting of IL-17 and IL-17F regulates inflammatory responses. Cell Res. 17:5 (2007), 435–440.
    • (2007) Cell Res. , vol.17 , Issue.5 , pp. 435-440
    • Chang, S.H.1    Dong, C.2
  • 16
    • 77952763410 scopus 로고    scopus 로고
    • IL-17RC is required for IL-17A- and IL-17F-dependent signaling and the pathogenesis of experimental autoimmune encephalomyelitis
    • Hu, Y., Ota, N., Peng, I., Refino, C.J., Danilenko, D.M., Caplazi, P., Ouyang, W., IL-17RC is required for IL-17A- and IL-17F-dependent signaling and the pathogenesis of experimental autoimmune encephalomyelitis. J. Immunol. 184:8 (2010), 4307–4316.
    • (2010) J. Immunol. , vol.184 , Issue.8 , pp. 4307-4316
    • Hu, Y.1    Ota, N.2    Peng, I.3    Refino, C.J.4    Danilenko, D.M.5    Caplazi, P.6    Ouyang, W.7
  • 20
    • 0037040251 scopus 로고    scopus 로고
    • Soluble and transmembrane isoforms of novel interleukin-17 receptor-like protein by RNA splicing and expression in prostate cancer
    • Haudenschild, D., Moseley, T., Rose, L., Reddi, A.H., Soluble and transmembrane isoforms of novel interleukin-17 receptor-like protein by RNA splicing and expression in prostate cancer. J. Biol. Chem. 277:6 (2002), 4309–4316.
    • (2002) J. Biol. Chem. , vol.277 , Issue.6 , pp. 4309-4316
    • Haudenschild, D.1    Moseley, T.2    Rose, L.3    Reddi, A.H.4
  • 21
    • 71849108118 scopus 로고    scopus 로고
    • Requirement of IL-17RA in Con A induced hepatitis and negative regulation of IL-17 production in mouse T cells
    • Nagata, T., McKinley, L., Peschon, J.J., Alcorn, J.F., Aujla, S.J., Kolls, J.K., Requirement of IL-17RA in Con A induced hepatitis and negative regulation of IL-17 production in mouse T cells. J. Immunol. 181:11 (2008), 7473–7479.
    • (2008) J. Immunol. , vol.181 , Issue.11 , pp. 7473-7479
    • Nagata, T.1    McKinley, L.2    Peschon, J.J.3    Alcorn, J.F.4    Aujla, S.J.5    Kolls, J.K.6
  • 24
    • 33846022750 scopus 로고    scopus 로고
    • Act1 adaptor protein is an immediate and essential signaling component of interleukin-17 receptor
    • Chang, S.H., Park, H., Dong, C., Act1 adaptor protein is an immediate and essential signaling component of interleukin-17 receptor. J. Biol. Chem. 281:47 (2006), 35603–35607.
    • (2006) J. Biol. Chem. , vol.281 , Issue.47 , pp. 35603-35607
    • Chang, S.H.1    Park, H.2    Dong, C.3
  • 25
    • 0033136695 scopus 로고    scopus 로고
    • NF-kappa B-inducing kinase is a common mediator of IL-17-, TNF-alpha-, and IL-1 beta-induced chemokine promoter activation in intestinal epithelial cells
    • Awane, M., Andres, P.G., Li, D.J., Reinecker, H.C., NF-kappa B-inducing kinase is a common mediator of IL-17-, TNF-alpha-, and IL-1 beta-induced chemokine promoter activation in intestinal epithelial cells. J. Immunol. 162:9 (1999), 5337–5344.
    • (1999) J. Immunol. , vol.162 , Issue.9 , pp. 5337-5344
    • Awane, M.1    Andres, P.G.2    Li, D.J.3    Reinecker, H.C.4
  • 26
    • 79955636935 scopus 로고    scopus 로고
    • IL-17 receptor signaling and T helper 17-mediated autoimmune demyelinating disease
    • Zepp, J., Wu, L., Li, X., IL-17 receptor signaling and T helper 17-mediated autoimmune demyelinating disease. Trends Immunol. 32:5 (2011), 232–239.
    • (2011) Trends Immunol. , vol.32 , Issue.5 , pp. 232-239
    • Zepp, J.1    Wu, L.2    Li, X.3
  • 28
    • 4544388059 scopus 로고    scopus 로고
    • Extracellular signal-regulated protein kinase mediates interleukin 17 (IL-17)-induced IL-8 secretion in Helicobacter pylori-infected human gastric epithelial cells
    • Sebkova, L., Pellicano, A., Monteleone, G., Grazioli, B., Guarnieri, G., Imeneo, M., Pallone, F., Luzza, F., Extracellular signal-regulated protein kinase mediates interleukin 17 (IL-17)-induced IL-8 secretion in Helicobacter pylori-infected human gastric epithelial cells. Infect. Immun. 72:9 (2004), 5019–5026.
    • (2004) Infect. Immun. , vol.72 , Issue.9 , pp. 5019-5026
    • Sebkova, L.1    Pellicano, A.2    Monteleone, G.3    Grazioli, B.4    Guarnieri, G.5    Imeneo, M.6    Pallone, F.7    Luzza, F.8
  • 29
    • 84906535154 scopus 로고    scopus 로고
    • The IL-23-IL-17 immune axis: from mechanisms to therapeutic testing
    • Gaffen, S.L., Jain, R., Garg, A.V., Cua, D.J., The IL-23-IL-17 immune axis: from mechanisms to therapeutic testing. Nat. Rev. Immunol. 14:9 (2014), 585–600.
    • (2014) Nat. Rev. Immunol. , vol.14 , Issue.9 , pp. 585-600
    • Gaffen, S.L.1    Jain, R.2    Garg, A.V.3    Cua, D.J.4
  • 30
    • 77649111732 scopus 로고    scopus 로고
    • IL-17A and IL-17F stimulate chemokines via MAPK pathways (ERK1/2 and p38 but not JNK) in mouse cultured mesangial cells: synergy with TNF-alpha and IL-1beta
    • Iyoda, M., Shibata, T., Kawaguchi, M., Hizawa, N., Yamaoka, T., Kokubu, F., Akizawa, T., IL-17A and IL-17F stimulate chemokines via MAPK pathways (ERK1/2 and p38 but not JNK) in mouse cultured mesangial cells: synergy with TNF-alpha and IL-1beta. Am. J. Physiol. Renal Physiol. 298:3 (2010), F779–F787.
    • (2010) Am. J. Physiol. Renal Physiol. , vol.298 , Issue.3 , pp. F779-F787
    • Iyoda, M.1    Shibata, T.2    Kawaguchi, M.3    Hizawa, N.4    Yamaoka, T.5    Kokubu, F.6    Akizawa, T.7
  • 31
    • 84977610573 scopus 로고    scopus 로고
    • IL-17 mediates inflammatory reactions via p38/c-Fos and JNK/c-Jun activation in an AP-1-dependent manner in human nucleus pulposus cells
    • Li, J.K., Nie, L., Zhao, Y.P., Zhang, Y.Q., Wang, X., Wang, S.S., Liu, Y., Zhao, H., Cheng, L., IL-17 mediates inflammatory reactions via p38/c-Fos and JNK/c-Jun activation in an AP-1-dependent manner in human nucleus pulposus cells. J. Transl. Med., 14, 2016, 77.
    • (2016) J. Transl. Med. , vol.14 , pp. 77
    • Li, J.K.1    Nie, L.2    Zhao, Y.P.3    Zhang, Y.Q.4    Wang, X.5    Wang, S.S.6    Liu, Y.7    Zhao, H.8    Cheng, L.9
  • 32
    • 84957593363 scopus 로고    scopus 로고
    • IL-17A increases TNF-alpha-induced COX-2 protein stability and augments PGE2 secretion from airway smooth muscle cells: impact on beta2-adrenergic receptor desensitization
    • Rumzhum, N.N., Patel, B.S., Prabhala, P., Gelissen, I.C., Oliver, B.G., Ammit, A.J., IL-17A increases TNF-alpha-induced COX-2 protein stability and augments PGE2 secretion from airway smooth muscle cells: impact on beta2-adrenergic receptor desensitization. Allergy 71:3 (2016), 387–396.
    • (2016) Allergy , vol.71 , Issue.3 , pp. 387-396
    • Rumzhum, N.N.1    Patel, B.S.2    Prabhala, P.3    Gelissen, I.C.4    Oliver, B.G.5    Ammit, A.J.6
  • 34
    • 79954414473 scopus 로고    scopus 로고
    • Signaling of interleukin-17 family cytokines in immunity and inflammation
    • Chang, S.H., Dong, C., Signaling of interleukin-17 family cytokines in immunity and inflammation. Cell. Signal. 23:7 (2011), 1069–1075.
    • (2011) Cell. Signal. , vol.23 , Issue.7 , pp. 1069-1075
    • Chang, S.H.1    Dong, C.2
  • 35
    • 1642576088 scopus 로고    scopus 로고
    • Functional cooperation between interleukin-17 and tumor necrosis factor-alpha is mediated by CCAAT/enhancer-binding protein family members
    • Ruddy, M.J., Wong, G.C., Liu, X.K., Yamamoto, H., Kasayama, S., Kirkwood, K.L., Gaffen, S.L., Functional cooperation between interleukin-17 and tumor necrosis factor-alpha is mediated by CCAAT/enhancer-binding protein family members. J. Biol. Chem. 279:4 (2004), 2559–2567.
    • (2004) J. Biol. Chem. , vol.279 , Issue.4 , pp. 2559-2567
    • Ruddy, M.J.1    Wong, G.C.2    Liu, X.K.3    Yamamoto, H.4    Kasayama, S.5    Kirkwood, K.L.6    Gaffen, S.L.7
  • 36
    • 33749318470 scopus 로고    scopus 로고
    • Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides
    • Liang, S.C., Tan, X.Y., Luxenberg, D.P., Karim, R., Dunussi-Joannopoulos, K., Collins, M., Fouser, L.A., Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides. J. Exp. Med. 203:10 (2006), 2271–2279.
    • (2006) J. Exp. Med. , vol.203 , Issue.10 , pp. 2271-2279
    • Liang, S.C.1    Tan, X.Y.2    Luxenberg, D.P.3    Karim, R.4    Dunussi-Joannopoulos, K.5    Collins, M.6    Fouser, L.A.7
  • 37
    • 77953495368 scopus 로고    scopus 로고
    • Pathological versus protective functions of IL-22 in airway inflammation are regulated by IL-17A
    • Sonnenberg, G.F., Nair, M.G., Kirn, T.J., Zaph, C., Fouser, L.A., Artis, D., Pathological versus protective functions of IL-22 in airway inflammation are regulated by IL-17A. J. Exp. Med. 207:6 (2010), 1293–1305.
    • (2010) J. Exp. Med. , vol.207 , Issue.6 , pp. 1293-1305
    • Sonnenberg, G.F.1    Nair, M.G.2    Kirn, T.J.3    Zaph, C.4    Fouser, L.A.5    Artis, D.6
  • 38
    • 35748973565 scopus 로고    scopus 로고
    • IL-17 enhances chemokine gene expression through mRNA stabilization
    • Hartupee, J., Liu, C., Novotny, M., Li, X., Hamilton, T., IL-17 enhances chemokine gene expression through mRNA stabilization. J. Immunol. 179:6 (2007), 4135–4141.
    • (2007) J. Immunol. , vol.179 , Issue.6 , pp. 4135-4141
    • Hartupee, J.1    Liu, C.2    Novotny, M.3    Li, X.4    Hamilton, T.5
  • 39
    • 84904872147 scopus 로고    scopus 로고
    • Early tissue responses in psoriasis to the antitumour necrosis factor-alpha biologic etanercept suggest reduced interleukin-17 receptor expression and signalling
    • Johnston, A., Guzman, A.M., Swindell, W.R., Wang, F., Kang, S., Gudjonsson, J.E., Early tissue responses in psoriasis to the antitumour necrosis factor-alpha biologic etanercept suggest reduced interleukin-17 receptor expression and signalling. Br. J. Dermatol. 171:1 (2014), 97–107.
    • (2014) Br. J. Dermatol. , vol.171 , Issue.1 , pp. 97-107
    • Johnston, A.1    Guzman, A.M.2    Swindell, W.R.3    Wang, F.4    Kang, S.5    Gudjonsson, J.E.6
  • 43
    • 84939533280 scopus 로고    scopus 로고
    • Immune requirements for protective Th17 recall responses to Mycobacterium tuberculosis challenge
    • Monin, L., Griffiths, K.L., Slight, S., Lin, Y., Rangel-Moreno, J., Khader, S.A., Immune requirements for protective Th17 recall responses to Mycobacterium tuberculosis challenge. Mucosal. Immunol. 8:5 (2015), 1099–1109.
    • (2015) Mucosal. Immunol. , vol.8 , Issue.5 , pp. 1099-1109
    • Monin, L.1    Griffiths, K.L.2    Slight, S.3    Lin, Y.4    Rangel-Moreno, J.5    Khader, S.A.6
  • 46
    • 85046362411 scopus 로고    scopus 로고
    • Chronic mucocutaneous candidiasis disease associated with inborn errors of IL-17 immunity
    • Okada, S., Puel, A., Casanova, J.L., Kobayashi, M., Chronic mucocutaneous candidiasis disease associated with inborn errors of IL-17 immunity. Clin. Transl. Immunol., 5(12), 2016, e114.
    • (2016) Clin. Transl. Immunol. , vol.5 , Issue.12 , pp. e114
    • Okada, S.1    Puel, A.2    Casanova, J.L.3    Kobayashi, M.4
  • 48
    • 85020111766 scopus 로고    scopus 로고
    • Candida infections in psoriasis and psoriatic arthritis patients treated with IL-17 inhibitors and their practical management
    • Saunte, D.M., Mrowietz, U., Puig, L., Zachariae, C., Candida infections in psoriasis and psoriatic arthritis patients treated with IL-17 inhibitors and their practical management. Br. J. Dermatol, 2016, 10.1111/bjd.15015.
    • (2016) Br. J. Dermatol
    • Saunte, D.M.1    Mrowietz, U.2    Puig, L.3    Zachariae, C.4
  • 53
    • 84883325367 scopus 로고    scopus 로고
    • IL-17 family cytokines mediated signaling in the pathogenesis of inflammatory diseases
    • Song, X., Qian, Y., IL-17 family cytokines mediated signaling in the pathogenesis of inflammatory diseases. Cell. Signal. 25:12 (2013), 2335–2347.
    • (2013) Cell. Signal. , vol.25 , Issue.12 , pp. 2335-2347
    • Song, X.1    Qian, Y.2
  • 54
    • 84959447961 scopus 로고    scopus 로고
    • The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring
    • Choi, G.B., Yim, Y.S., Wong, H., Kim, S., Kim, H., Kim, S.V., Hoeffer, C.A., Littman, D.R., Huh, J.R., The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring. Science 351:6276 (2016), 933–939.
    • (2016) Science , vol.351 , Issue.6276 , pp. 933-939
    • Choi, G.B.1    Yim, Y.S.2    Wong, H.3    Kim, S.4    Kim, H.5    Kim, S.V.6    Hoeffer, C.A.7    Littman, D.R.8    Huh, J.R.9
  • 57
    • 84891740105 scopus 로고    scopus 로고
    • Efficacy and safety of secukinumab, a fully human anti-interleukin-17A monoclonal antibody, in patients with moderate-to-severe psoriatic arthritis: a 24-week, randomised, double-blind, placebo-controlled, phase II proof-of-concept trial
    • McInnes, I.B., Sieper, J., Braun, J., Emery, P., vanderHeijde, D., Isaacs, J.D., Dahmen, G., Wollenhaupt, J., Schulze-Koops, H., Kogan, J., Ma, S., Schumacher, M.M., Bertolino, A.P., Hueber, W., Tak, P.P., Efficacy and safety of secukinumab, a fully human anti-interleukin-17A monoclonal antibody, in patients with moderate-to-severe psoriatic arthritis: a 24-week, randomised, double-blind, placebo-controlled, phase II proof-of-concept trial. Ann. Rheum. Dis. 73:2 (2014), 349–356.
    • (2014) Ann. Rheum. Dis. , vol.73 , Issue.2 , pp. 349-356
    • McInnes, I.B.1    Sieper, J.2    Braun, J.3    Emery, P.4    vanderHeijde, D.5    Isaacs, J.D.6    Dahmen, G.7    Wollenhaupt, J.8    Schulze-Koops, H.9    Kogan, J.10    Ma, S.11    Schumacher, M.M.12    Bertolino, A.P.13    Hueber, W.14    Tak, P.P.15
  • 58
    • 84902177664 scopus 로고    scopus 로고
    • Efficacy and safety of secukinumab in chronic plaque psoriasis and psoriatic arthritis therapy
    • Gisondi, P., Dalle Vedove, C., Girolomoni, G., Efficacy and safety of secukinumab in chronic plaque psoriasis and psoriatic arthritis therapy. Dermatol. Ther. 4:1 (2014), 1–9.
    • (2014) Dermatol. Ther. , vol.4 , Issue.1 , pp. 1-9
    • Gisondi, P.1    Dalle Vedove, C.2    Girolomoni, G.3
  • 60
    • 85006307134 scopus 로고    scopus 로고
    • IL-17 blockade in psoriasis
    • Burkett, P.R., Kuchroo, V.K., IL-17 blockade in psoriasis. Cell, 167(7), 2016, 1669.
    • (2016) Cell , vol.167 , Issue.7 , pp. 1669
    • Burkett, P.R.1    Kuchroo, V.K.2
  • 61
    • 85033664735 scopus 로고    scopus 로고
    • Secukinumab for the treatment of psoriatic arthritis: comparative effectiveness versus adalimumab using a matching-adjusted indirect comparison
    • Nash, P., McInnes, I.B., Mease, P.J., Choy, E.H., Thom, H., Kalyvas, C., Gandhi, K., Mpofu, S., Jugl, S., Secukinumab for the treatment of psoriatic arthritis: comparative effectiveness versus adalimumab using a matching-adjusted indirect comparison. Arthritis Rheumatol., 68(Suppl. 10), 2016.
    • (2016) Arthritis Rheumatol. , vol.68
    • Nash, P.1    McInnes, I.B.2    Mease, P.J.3    Choy, E.H.4    Thom, H.5    Kalyvas, C.6    Gandhi, K.7    Mpofu, S.8    Jugl, S.9
  • 62
    • 84939463415 scopus 로고    scopus 로고
    • Secukinumab is superior to ustekinumab in clearing skin of subjects with moderate to severe plaque psoriasis: CLEAR, a randomized controlled trial
    • Thaci, D., Blauvelt, A., Reich, K., Tsai, T.F., Vanaclocha, F., Kingo, K., Ziv, M., Pinter, A., Hugot, S., You, R., Milutinovic, M., Secukinumab is superior to ustekinumab in clearing skin of subjects with moderate to severe plaque psoriasis: CLEAR, a randomized controlled trial. J. Am. Acad. Dermatol. 73:3 (2015), 400–409.
    • (2015) J. Am. Acad. Dermatol. , vol.73 , Issue.3 , pp. 400-409
    • Thaci, D.1    Blauvelt, A.2    Reich, K.3    Tsai, T.F.4    Vanaclocha, F.5    Kingo, K.6    Ziv, M.7    Pinter, A.8    Hugot, S.9    You, R.10    Milutinovic, M.11
  • 64
    • 81255158786 scopus 로고    scopus 로고
    • IL-17RE is the functional receptor for IL-17C and mediates mucosal immunity to infection with intestinal pathogens
    • Song, X., Zhu, S., Shi, P., Liu, Y., Shi, Y., Levin, S.D., Qian, Y., IL-17RE is the functional receptor for IL-17C and mediates mucosal immunity to infection with intestinal pathogens. Nat. Immunol. 12:12 (2011), 1151–1158.
    • (2011) Nat. Immunol. , vol.12 , Issue.12 , pp. 1151-1158
    • Song, X.1    Zhu, S.2    Shi, P.3    Liu, Y.4    Shi, Y.5    Levin, S.D.6    Qian, Y.7
  • 68
    • 84953408338 scopus 로고    scopus 로고
    • Brodalumab and suicidal ideation in the context of a recent economic crisis in the United States
    • Danesh, M.J., Kimball, A.B., Brodalumab and suicidal ideation in the context of a recent economic crisis in the United States. J. Am. Acad. Dermatol. 74:1 (2016), 190–192.
    • (2016) J. Am. Acad. Dermatol. , vol.74 , Issue.1 , pp. 190-192
    • Danesh, M.J.1    Kimball, A.B.2
  • 69
    • 84996479960 scopus 로고    scopus 로고
    • No meaningful association between suicidal behavior and the use of IL-17A-neutralizing or IL-17RA-blocking agents
    • Chiricozzi, A., Romanelli, M., Saraceno, R., Torres, T., No meaningful association between suicidal behavior and the use of IL-17A-neutralizing or IL-17RA-blocking agents. Expert Opin. Drug Saf. 15:12 (2016), 1653–1659.
    • (2016) Expert Opin. Drug Saf. , vol.15 , Issue.12 , pp. 1653-1659
    • Chiricozzi, A.1    Romanelli, M.2    Saraceno, R.3    Torres, T.4
  • 71
    • 84964301265 scopus 로고    scopus 로고
    • Anti-IL-17 therapy in treatment of rheumatoid arthritis: a systematic literature review and meta-analysis of randomized controlled trials
    • Kunwar, S., Dahal, K., Sharma, S., Anti-IL-17 therapy in treatment of rheumatoid arthritis: a systematic literature review and meta-analysis of randomized controlled trials. Rheumatol. Int. 36:8 (2016), 1065–1075.
    • (2016) Rheumatol. Int. , vol.36 , Issue.8 , pp. 1065-1075
    • Kunwar, S.1    Dahal, K.2    Sharma, S.3
  • 72
    • 84958781295 scopus 로고    scopus 로고
    • Enigma of IL-17 and Th17Cells in rheumatoid arthritis and in autoimmune animal models of arthritis
    • Kugyelka, R., Kohl, Z., Olasz, K., Mikecz, K., Rauch, T.A., Glant, T.T., Boldizsar, F., Enigma of IL-17 and Th17Cells in rheumatoid arthritis and in autoimmune animal models of arthritis. Mediators Inflamm., 2016, 2016, 6145810.
    • (2016) Mediators Inflamm. , vol.2016 , pp. 6145810
    • Kugyelka, R.1    Kohl, Z.2    Olasz, K.3    Mikecz, K.4    Rauch, T.A.5    Glant, T.T.6    Boldizsar, F.7
  • 73
    • 84965036792 scopus 로고    scopus 로고
    • Activity of secukinumab, an anti-IL-17A antibody, on brain lesions in RRMS: results from a randomized, proof-of-concept study
    • Havrdova, E., Belova, A., Goloborodko, A., Tisserant, A., Wright, A., Wallstroem, E., Garren, H., Maguire, R.P., Johns, D.R., Activity of secukinumab, an anti-IL-17A antibody, on brain lesions in RRMS: results from a randomized, proof-of-concept study. J. Neurol. 263:7 (2016), 1287–1295.
    • (2016) J. Neurol. , vol.263 , Issue.7 , pp. 1287-1295
    • Havrdova, E.1    Belova, A.2    Goloborodko, A.3    Tisserant, A.4    Wright, A.5    Wallstroem, E.6    Garren, H.7    Maguire, R.P.8    Johns, D.R.9
  • 76
    • 84963607000 scopus 로고    scopus 로고
    • Th17 cell pathway in human immunity: lessons from genetics and therapeutic interventions
    • Patel, D.D., Kuchroo, V.K., Th17 cell pathway in human immunity: lessons from genetics and therapeutic interventions. Immunity 43:6 (2015), 1040–1051.
    • (2015) Immunity , vol.43 , Issue.6 , pp. 1040-1051
    • Patel, D.D.1    Kuchroo, V.K.2
  • 77
    • 84969759480 scopus 로고    scopus 로고
    • A revolutionary therapeutic approach for psoriasis: bispecific biological agents
    • Torres, T., Romanelli, M., Chiricozzi, A., A revolutionary therapeutic approach for psoriasis: bispecific biological agents. Expert Opin. Investig. Drugs 25:7 (2016), 751–754.
    • (2016) Expert Opin. Investig. Drugs , vol.25 , Issue.7 , pp. 751-754
    • Torres, T.1    Romanelli, M.2    Chiricozzi, A.3
  • 78
  • 79
    • 84906316949 scopus 로고    scopus 로고
    • Inhibiting RORgammat/Th17 axis for autoimmune disorders
    • Isono, F., Fujita-Sato, S., Ito, S., Inhibiting RORgammat/Th17 axis for autoimmune disorders. Drug Discov. Today 19:8 (2014), 1205–1211.
    • (2014) Drug Discov. Today , vol.19 , Issue.8 , pp. 1205-1211
    • Isono, F.1    Fujita-Sato, S.2    Ito, S.3
  • 80
    • 85004168918 scopus 로고    scopus 로고
    • RORgamma antagonists and inverse agonists: a patent review
    • Bronner, S.M., Zbieg, J.R., Crawford, J.J., RORgamma antagonists and inverse agonists: a patent review. Expert Opin. Ther. Patents 27:1 (2017), 101–112.
    • (2017) Expert Opin. Ther. Patents , vol.27 , Issue.1 , pp. 101-112
    • Bronner, S.M.1    Zbieg, J.R.2    Crawford, J.J.3
  • 82
    • 10344256237 scopus 로고    scopus 로고
    • Psoriasis triggered by toll-like receptor 7 agonist imiquimod in the presence of dermal plasmacytoid dendritic cell precursors
    • Gilliet, M., Conrad, C., Geiges, M., Cozzio, A., Thurlimann, W., Burg, G., Nestle, F.O., Dummer, R., Psoriasis triggered by toll-like receptor 7 agonist imiquimod in the presence of dermal plasmacytoid dendritic cell precursors. Arch. Dermatol. 140:12 (2004), 1490–1495.
    • (2004) Arch. Dermatol. , vol.140 , Issue.12 , pp. 1490-1495
    • Gilliet, M.1    Conrad, C.2    Geiges, M.3    Cozzio, A.4    Thurlimann, W.5    Burg, G.6    Nestle, F.O.7    Dummer, R.8
  • 83
    • 84937945349 scopus 로고    scopus 로고
    • Inflammation induces dermal Vgamma4+ gammadeltaT17 memory-like cells that travel to distant skin and accelerate secondary IL-17-driven responses
    • Ramirez-Valle, F., Gray, E.E., Cyster, J.G., Inflammation induces dermal Vgamma4+ gammadeltaT17 memory-like cells that travel to distant skin and accelerate secondary IL-17-driven responses. Proc. Natl. Acad. Sci. U. S. A. 112:26 (2015), 8046–8051.
    • (2015) Proc. Natl. Acad. Sci. U. S. A. , vol.112 , Issue.26 , pp. 8046-8051
    • Ramirez-Valle, F.1    Gray, E.E.2    Cyster, J.G.3
  • 84
    • 84861801523 scopus 로고    scopus 로고
    • Rorgammat+ innate lymphocytes and gammadelta T cells initiate psoriasiform plaque formation in mice
    • Pantelyushin, S., Haak, S., Ingold, B., Kulig, P., Heppner, F.L., Navarini, A.A., Becher, B., Rorgammat+ innate lymphocytes and gammadelta T cells initiate psoriasiform plaque formation in mice. J. Clin. Invest. 122:6 (2012), 2252–2256.
    • (2012) J. Clin. Invest. , vol.122 , Issue.6 , pp. 2252-2256
    • Pantelyushin, S.1    Haak, S.2    Ingold, B.3    Kulig, P.4    Heppner, F.L.5    Navarini, A.A.6    Becher, B.7
  • 87
    • 81455141962 scopus 로고    scopus 로고
    • Epidermal CCR6+ {gamma}{delta} T cells are major producers of IL-22 and IL-17 in a murine model of psoriasiform dermatitis
    • Mabuchi, T., Takekoshi, T., Hwang, S.T., Epidermal CCR6+ {gamma}{delta} T cells are major producers of IL-22 and IL-17 in a murine model of psoriasiform dermatitis. J. Immunol. 187:10 (2011), 5026–5031.
    • (2011) J. Immunol. , vol.187 , Issue.10 , pp. 5026-5031
    • Mabuchi, T.1    Takekoshi, T.2    Hwang, S.T.3
  • 90
    • 77954520794 scopus 로고    scopus 로고
    • Ezrin, maspin, peroxiredoxin 2, and heat shock protein 27: potential targets of a streptococcal-induced autoimmune response in psoriasis
    • Besgen, P., Trommler, P., Vollmer, S., Prinz, J.C., Ezrin, maspin, peroxiredoxin 2, and heat shock protein 27: potential targets of a streptococcal-induced autoimmune response in psoriasis. J. Immunol. 184:9 (2010), 5392–5402.
    • (2010) J. Immunol. , vol.184 , Issue.9 , pp. 5392-5402
    • Besgen, P.1    Trommler, P.2    Vollmer, S.3    Prinz, J.C.4
  • 93
    • 69449095507 scopus 로고    scopus 로고
    • IL-17-producing CD8+ T lymphocytes from psoriasis skin plaques are cytotoxic effector cells that secrete Th17-related cytokines
    • Ortega, C., Fernandez, A.S., Carrillo, J.M., Romero, P., Molina, I.J., Moreno, J.C., Santamaria, M., IL-17-producing CD8+ T lymphocytes from psoriasis skin plaques are cytotoxic effector cells that secrete Th17-related cytokines. J. Leukoc. Biol. 86:2 (2009), 435–443.
    • (2009) J. Leukoc. Biol. , vol.86 , Issue.2 , pp. 435-443
    • Ortega, C.1    Fernandez, A.S.2    Carrillo, J.M.3    Romero, P.4    Molina, I.J.5    Moreno, J.C.6    Santamaria, M.7
  • 95
    • 84897495287 scopus 로고    scopus 로고
    • Epidermal Th22 and Tc17 cells form a localized disease memory in clinically healed psoriasis
    • Cheuk, S., Wiken, M., Blomqvist, L., Nylen, S., Talme, T., Stahle, M., Eidsmo, L., Epidermal Th22 and Tc17 cells form a localized disease memory in clinically healed psoriasis. J. Immunol. 192:7 (2014), 3111–3120.
    • (2014) J. Immunol. , vol.192 , Issue.7 , pp. 3111-3120
    • Cheuk, S.1    Wiken, M.2    Blomqvist, L.3    Nylen, S.4    Talme, T.5    Stahle, M.6    Eidsmo, L.7
  • 96
    • 18044377011 scopus 로고    scopus 로고
    • Interleukin-17 enhances bFGF-, HGF- and VEGF-induced growth of vascular endothelial cells
    • Takahashi, H., Numasaki, M., Lotze, M.T., Sasaki, H., Interleukin-17 enhances bFGF-, HGF- and VEGF-induced growth of vascular endothelial cells. Immunol. Lett. 98:2 (2005), 189–193.
    • (2005) Immunol. Lett. , vol.98 , Issue.2 , pp. 189-193
    • Takahashi, H.1    Numasaki, M.2    Lotze, M.T.3    Sasaki, H.4


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