메뉴 건너뛰기




Volumn 2016, Issue , 2016, Pages

Enigma of IL-17 and Th17 cells in rheumatoid arthritis and in autoimmune animal models of arthritis

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 17; PROTEOGLYCAN;

EID: 84958781295     PISSN: 09629351     EISSN: 14661861     Source Type: Journal    
DOI: 10.1155/2016/6145810     Document Type: Article
Times cited : (79)

References (88)
  • 1
    • 77957196913 scopus 로고    scopus 로고
    • Rheumatoid arthritis
    • D. L. Scott, F. Wolfe, and T. W. J. Huizinga, "Rheumatoid arthritis, " The Lancet, vol. 376, no. 9746, pp. 1094-1108, 2010.
    • (2010) The Lancet , vol.376 , Issue.9746 , pp. 1094-1108
    • Scott, D.L.1    Wolfe, F.2    Huizinga, T.W.J.3
  • 2
    • 0035071010 scopus 로고    scopus 로고
    • The first description of rheumatoid arthritis. Unabridged text of the doctoral dissertation presented in 1800
    • A. J. Landré-Beauvais, "The first description of rheumatoid arthritis. Unabridged text of the doctoral dissertation presented in 1800, " Joint Bone Spine, vol. 68, no. 2, pp. 130-143, 2001.
    • (2001) Joint Bone Spine , vol.68 , Issue.2 , pp. 130-143
    • Landré-Beauvais, A.J.1
  • 4
    • 79952026221 scopus 로고    scopus 로고
    • Abatacept treatment for rheumatoid arthritis
    • M. Schiff, "Abatacept treatment for rheumatoid arthritis, " Rheumatology, vol. 50, no. 3, pp. 437-449, 2011.
    • (2011) Rheumatology , vol.50 , Issue.3 , pp. 437-449
    • Schiff, M.1
  • 5
    • 40449141770 scopus 로고    scopus 로고
    • Human T cells that are able to produce IL-17 express the chemokine receptor CCR6
    • S. P. Singh, H. H. Zhang, J. F. Foley, M. N. Hedrick, and J. M. Farber, "Human T cells that are able to produce IL-17 express the chemokine receptor CCR6, " Journal of Immunology, vol. 180, no. 1, pp. 214-221, 2008.
    • (2008) Journal of Immunology , vol.180 , Issue.1 , pp. 214-221
    • Singh, S.P.1    Zhang, H.H.2    Foley, J.F.3    Hedrick, M.N.4    Farber, J.M.5
  • 6
    • 34548125305 scopus 로고    scopus 로고
    • Interleukins 1β and 6 but not transforming growth factor-β are essential for the differentiation of interleukin 17-producing human T helper cells
    • E. V. Acosta-Rodriguez, G. Napolitani, A. Lanzavecchia, and F. Sallusto, "Interleukins 1β and 6 but not transforming growth factor-β are essential for the differentiation of interleukin 17-producing human T helper cells, " Nature Immunology, vol. 8, no. 9, pp. 942-949, 2007.
    • (2007) Nature Immunology , vol.8 , Issue.9 , pp. 942-949
    • Acosta-Rodriguez, E.V.1    Napolitani, G.2    Lanzavecchia, A.3    Sallusto, F.4
  • 7
    • 84874234535 scopus 로고    scopus 로고
    • Human inflammatory dendritic cells induce Th17 cell differentiation
    • E. Segura, M. Touzot, A. Bohineust et al., "Human inflammatory dendritic cells induce Th17 cell differentiation, " Immunity, vol. 38, no. 2, pp. 336-348, 2013.
    • (2013) Immunity , vol.38 , Issue.2 , pp. 336-348
    • Segura, E.1    Touzot, M.2    Bohineust, A.3
  • 8
    • 78650764391 scopus 로고    scopus 로고
    • Th17 cells, but not Th1 cells, from patients with early rheumatoid arthritis are potent inducers of matrix metalloproteinases and proinflammatory cytokines upon synovial fibroblast interaction, including autocrine interleukin-17A production
    • J. P. van Hamburg, P. S. Asmawidjaja, N. Davelaar et al., "Th17 cells, but not Th1 cells, from patients with early rheumatoid arthritis are potent inducers of matrix metalloproteinases and proinflammatory cytokines upon synovial fibroblast interaction, including autocrine interleukin-17A production, " Arthritis & Rheumatism, vol. 63, no. 1, pp. 73-83, 2011.
    • (2011) Arthritis & Rheumatism , vol.63 , Issue.1 , pp. 73-83
    • Van Hamburg, J.P.1    Asmawidjaja, P.S.2    Davelaar, N.3
  • 9
    • 84930181101 scopus 로고    scopus 로고
    • The role and modulation of CCR6+ Th17 cell populations in rheumatoid arthritis
    • S. M. J. Paulissen, J. P. van Hamburg, W. Dankers, and E. Lubberts, "The role and modulation of CCR6+ Th17 cell populations in rheumatoid arthritis, " Cytokine, vol. 74, no. 1, pp. 43-53, 2015.
    • (2015) Cytokine , vol.74 , Issue.1 , pp. 43-53
    • Paulissen, S.M.J.1    Van Hamburg, J.P.2    Dankers, W.3    Lubberts, E.4
  • 10
    • 84908134702 scopus 로고    scopus 로고
    • Heterogeneous expression pattern of interleukin 17A (IL-17A), IL-17F and their receptors in synovium of rheumatoid arthritis, psoriatic arthritis and osteoarthritis: Possible explanation for nonresponse to anti-IL-17 therapy?
    • article 426
    • L. G. M. van Baarsen, M. C. Lebre, D. van der Coelen et al., "Heterogeneous expression pattern of interleukin 17A (IL-17A), IL-17F and their receptors in synovium of rheumatoid arthritis, psoriatic arthritis and osteoarthritis: possible explanation for nonresponse to anti-IL-17 therapy?" Arthritis Research & Therapy, vol. 16, no. 4, article 426, 2014.
    • (2014) Arthritis Research & Therapy , vol.16 , Issue.4
    • Van Baarsen, L.G.M.1    Lebre, M.C.2    Coelen Der D.Van3
  • 11
    • 78651371338 scopus 로고    scopus 로고
    • Synovial fluidderived T helper 17 cells correlate with inflammatory activity in arthritis, irrespectively of diagnosis
    • G. Zizzo, M. De Santis, S. L. Bosello et al., "Synovial fluidderived T helper 17 cells correlate with inflammatory activity in arthritis, irrespectively of diagnosis, " Clinical Immunology, vol. 138, no. 1, pp. 107-116, 2011.
    • (2011) Clinical Immunology , vol.138 , Issue.1 , pp. 107-116
    • Zizzo, G.1    De Santis, M.2    Bosello, S.L.3
  • 12
    • 84929305989 scopus 로고    scopus 로고
    • Involvement of RORγt overexpressing T cells in the development of autoimmune arthritis in mice
    • Y. Kondo, Z. Yao, M. Tahara et al., "Involvement of RORγt overexpressing T cells in the development of autoimmune arthritis in mice, " Arthritis Research & Therapy, vol. 17, no. 1, 2015.
    • (2015) Arthritis Research & Therapy , vol.17 , Issue.1
    • Kondo, Y.1    Yao, Z.2    Tahara, M.3
  • 13
    • 36549019912 scopus 로고    scopus 로고
    • Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model
    • K. Hirota, H. Yoshitomi, M. Hashimoto et al., "Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model, " Journal of Experimental Medicine, vol. 204, no. 12, pp. 2803-2812, 2007.
    • (2007) Journal of Experimental Medicine , vol.204 , Issue.12 , pp. 2803-2812
    • Hirota, K.1    Yoshitomi, H.2    Hashimoto, M.3
  • 14
    • 0027215897 scopus 로고
    • CTLA-8, cloned from an activated T cell, bearing AUrich messenger RNA instability sequences, and homologous to a herpesvirus Saimiri gene
    • E. Rouvier, M.-F. Luciani, M.-G. Mattei, F. Denizot, and P. Golstein, "CTLA-8, cloned from an activated T cell, bearing AUrich messenger RNA instability sequences, and homologous to a herpesvirus Saimiri gene, "The Journal of Immunology, vol. 150, no. 12, pp. 5445-5456, 1993.
    • (1993) The Journal of Immunology , vol.150 , Issue.12 , pp. 5445-5456
    • Rouvier, E.1    Luciani, M.-F.2    Mattei, M.-G.3    Denizot, F.4    Golstein, P.5
  • 15
    • 0029555301 scopus 로고
    • Herpesvirus Saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor
    • Z. Yao, W. C. Fanslow, M. F. Seldin et al., "Herpesvirus Saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor, " Immunity, vol. 3, no. 6, pp. 811-821, 1995.
    • (1995) Immunity , vol.3 , Issue.6 , pp. 811-821
    • Yao, Z.1    Fanslow, W.C.2    Seldin, M.F.3
  • 16
    • 15844402155 scopus 로고    scopus 로고
    • T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines
    • F. Fossiez, O. Djossou, P. Chomarat et al., "T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines, " Journal of Experimental Medicine, vol. 183, no. 6, pp. 2593-2603, 1996.
    • (1996) Journal of Experimental Medicine , vol.183 , Issue.6 , pp. 2593-2603
    • Fossiez, F.1    Djossou, O.2    Chomarat, P.3
  • 17
    • 0029838420 scopus 로고    scopus 로고
    • Mouse IL-17: A cytokine preferentially expressed by αβTCR+CD4-CD8-T cells
    • J. Kennedy, D. L. Rossi, S. M. Zurawski et al., "Mouse IL-17: a cytokine preferentially expressed by αβTCR+CD4-CD8-T cells, " Journal of Interferon & Cytokine Research, vol. 16, no. 8, pp. 611-617, 1996.
    • (1996) Journal of Interferon & Cytokine Research , vol.16 , Issue.8 , pp. 611-617
    • Kennedy, J.1    Rossi, D.L.2    Zurawski, S.M.3
  • 18
    • 0022640843 scopus 로고
    • Two types ofmurine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins
    • T. R. Mosmann, H. Cherwinski, M. W. Bond, M. A. Giedlin, and R. L. Coffman, "Two types ofmurine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins, " The Journal of Immunology, vol. 136, no. 7, pp. 2348-2357, 1986.
    • (1986) The Journal of Immunology , vol.136 , Issue.7 , pp. 2348-2357
    • Mosmann, T.R.1    Cherwinski, H.2    Bond, M.W.3    Giedlin, M.A.4    Coffman, R.L.5
  • 19
    • 0034661356 scopus 로고    scopus 로고
    • Lineage commitment in the immune system: The T helper lymphocyte grows up
    • L. H. Glimcher and K. M. Murphy, "Lineage commitment in the immune system: the T helper lymphocyte grows up, " Genes and Development, vol. 14, no. 14, pp. 1693-1711, 2000.
    • (2000) Genes and Development , vol.14 , Issue.14 , pp. 1693-1711
    • Glimcher, L.H.1    Murphy, K.M.2
  • 20
    • 33846966636 scopus 로고    scopus 로고
    • A brief history of TH17, the first major revision in the TH1/TH2 hypothesis of T cell-mediated tissue damage
    • L. Steinman, "A brief history of TH17, the first major revision in the TH1/TH2 hypothesis of T cell-mediated tissue damage, " Nature Medicine, vol. 13, no. 2, pp. 139-145, 2007.
    • (2007) Nature Medicine , vol.13 , Issue.2 , pp. 139-145
    • Steinman, L.1
  • 21
    • 0034541221 scopus 로고    scopus 로고
    • Microbial lipopeptides induce the production of IL-17 in Th cells
    • C. Infante-Duarte, H. F. Horton, M. C. Byrne, and T. Kamradt, "Microbial lipopeptides induce the production of IL-17 in Th cells, " Journal of Immunology, vol. 165, no. 11, pp. 6107-6115, 2000.
    • (2000) Journal of Immunology , vol.165 , Issue.11 , pp. 6107-6115
    • Infante-Duarte, C.1    Horton, H.F.2    Byrne, M.C.3    Kamradt, T.4
  • 23
    • 84885179192 scopus 로고    scopus 로고
    • IL-17 family: Cytokines, receptors and signaling
    • C. Gu, L. Wu, and X. Li, "IL-17 family: cytokines, receptors and signaling, " Cytokine, vol. 64, no. 2, pp. 477-485, 2013.
    • (2013) Cytokine , vol.64 , Issue.2 , pp. 477-485
    • Gu, C.1    Wu, L.2    Li, X.3
  • 24
    • 41549135632 scopus 로고    scopus 로고
    • The biological functions of T helper 17 cell effector cytokines in inflammation
    • W. Ouyang, J. K. Kolls, and Y. Zheng, "The biological functions of T helper 17 cell effector cytokines in inflammation, " Immunity, vol. 28, no. 4, pp. 454-467, 2008.
    • (2008) Immunity , vol.28 , Issue.4 , pp. 454-467
    • Ouyang, W.1    Kolls, J.K.2    Zheng, Y.3
  • 25
    • 0032939156 scopus 로고    scopus 로고
    • Human interleukin-17: A T cell-derived proinflammatory cytokine produced by the rheumatoid synovium
    • M. Chabaud, J. M. Durand, N. Buchs et al., "Human interleukin-17: a T cell-derived proinflammatory cytokine produced by the rheumatoid synovium, " Arthritis and Rheumatism, vol. 42, no. 5, pp. 963-970, 1999.
    • (1999) Arthritis and Rheumatism , vol.42 , Issue.5 , pp. 963-970
    • Chabaud, M.1    Durand, J.M.2    Buchs, N.3
  • 27
    • 84923336314 scopus 로고    scopus 로고
    • Cytokine-mediated bone destruction in rheumatoid arthritis
    • Article ID263625, 15 pages
    • S. M. Jung, K. W. Kim, C.-W. Yang, S.-H. Park, and J. H. Ju, "Cytokine-mediated bone destruction in rheumatoid arthritis, " Journal of Immunology Research, vol. 2014, Article ID263625, 15 pages, 2014.
    • (2014) Journal of Immunology Research , vol.2014
    • Jung, S.M.1    Kim, K.W.2    Yang, C.-W.3    Park, S.-H.4    Ju, J.H.5
  • 28
    • 84880596502 scopus 로고    scopus 로고
    • Biologic therapies and systemic bone loss in rheumatoid arthritis
    • T. Dimitroulas, S. N. Nikas, P. Trontzas, and G. D. Kitas, "Biologic therapies and systemic bone loss in rheumatoid arthritis, " Autoimmunity Reviews, vol. 12, no. 10, pp. 958-966, 2013.
    • (2013) Autoimmunity Reviews , vol.12 , Issue.10 , pp. 958-966
    • Dimitroulas, T.1    Nikas, S.N.2    Trontzas, P.3    Kitas, G.D.4
  • 29
  • 30
    • 0033134608 scopus 로고    scopus 로고
    • IL-17 in synovial fluids frompatients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis
    • S. Kotake, N. Udagawa, N. Takahashi et al., "IL-17 in synovial fluids frompatients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis, "The Journal of Clinical Investigation, vol. 103, no. 9, pp. 1345-1352, 1999.
    • (1999) The Journal of Clinical Investigation , vol.103 , Issue.9 , pp. 1345-1352
    • Kotake, S.1    Udagawa, N.2    Takahashi, N.3
  • 31
    • 0035048597 scopus 로고    scopus 로고
    • IL-17 derived from juxta-articular bone and synoviumcontributes to joint degradation in rheumatoid arthritis
    • M. Chabaud, E. Lubberts, L. Joosten, W. van Den Berg, and P. Miossec, "IL-17 derived from juxta-articular bone and synoviumcontributes to joint degradation in rheumatoid arthritis, " Arthritis Research, vol. 3, no. 3, pp. 168-177, 2001.
    • (2001) Arthritis Research , vol.3 , Issue.3 , pp. 168-177
    • Chabaud, M.1    Lubberts, E.2    Joosten, L.3    Berg Den W.Van4    Miossec, P.5
  • 32
    • 77949454280 scopus 로고    scopus 로고
    • Interleukin-17A upregulates receptor activator of NF-κB on osteoclast precursors
    • article R29
    • I. E. Adamopoulos, C.-C. Chao, R. Geissler et al., "Interleukin-17A upregulates receptor activator of NF-κB on osteoclast precursors, " Arthritis Research and Therapy, vol. 12, no. 1, article R29, 2010.
    • (2010) Arthritis Research and Therapy , vol.12 , Issue.1
    • Adamopoulos, I.E.1    Chao, C.-C.2    Geissler, R.3
  • 33
    • 79960119130 scopus 로고    scopus 로고
    • Differentiation, phenotype, and function of interleukin-17-producing human Vγ9Vδ2 T cells
    • N. Caccamo, C. LaMendola, V. Orlando et al., "Differentiation, phenotype, and function of interleukin-17-producing human Vγ9Vδ2 T cells, " Blood, vol. 118, no. 1, pp. 129-138, 2011.
    • (2011) Blood , vol.118 , Issue.1 , pp. 129-138
    • Caccamo, N.1    LaMendola, C.2    Orlando, V.3
  • 34
    • 0025828573 scopus 로고
    • Elevation of a gamma deltaTcell subset inperipheral bloodand synovial fluid of patients with rheumatoid arthritis
    • E. C. Keystone, C. Rittershaus, N. Wood et al., "Elevation of a gamma deltaTcell subset inperipheral bloodand synovial fluid of patients with rheumatoid arthritis, " Clinical and Experimental Immunology, vol. 84, no. 1, pp. 78-82, 1991.
    • (1991) Clinical and Experimental Immunology , vol.84 , Issue.1 , pp. 78-82
    • Keystone, E.C.1    Rittershaus, C.2    Wood, N.3
  • 35
    • 68049097199 scopus 로고    scopus 로고
    • Gamma/delta T cells are the predominant source of interleukin-17 in affected joints in collagen-induced arthritis, but not in rheumatoid arthritis
    • Y. Ito, T. Usui, S. Kobayashi et al., "Gamma/delta T cells are the predominant source of interleukin-17 in affected joints in collagen-induced arthritis, but not in rheumatoid arthritis, " Arthritis & Rheumatism, vol. 60, no. 8, pp. 2294-2303, 2009.
    • (2009) Arthritis & Rheumatism , vol.60 , Issue.8 , pp. 2294-2303
    • Ito, Y.1    Usui, T.2    Kobayashi, S.3
  • 36
    • 84885157712 scopus 로고    scopus 로고
    • Activated γδ T cells inhibit osteoclast differentiation and resorptive activity in vitro
    • A. Pappalardo and K. Thompson, "Activated γδ T cells inhibit osteoclast differentiation and resorptive activity in vitro, " Clinical and Experimental Immunology, vol. 174, no. 2, pp. 281-291, 2013.
    • (2013) Clinical and Experimental Immunology , vol.174 , Issue.2 , pp. 281-291
    • Pappalardo, A.1    Thompson, K.2
  • 37
    • 79951846831 scopus 로고    scopus 로고
    • + γδ T cells, drive arthritic bone destruction in mice and humans
    • + γδ T cells, drive arthritic bone destruction in mice and humans, " The Journal of Immunology, vol. 186, no. 4, pp. 2602-2612, 2011.
    • (2011) The Journal of Immunology , vol.186 , Issue.4 , pp. 2602-2612
    • Pöllinger, B.1    Junt, T.2    Metzler, B.3
  • 38
    • 33846456970 scopus 로고    scopus 로고
    • T cell selfreactivity forms a cytokine milieu for spontaneous development of IL-17+ Th cells that cause autoimmune arthritis
    • K. Hirota, M. Hashimoto, H. Yoshitomi et al., "T cell selfreactivity forms a cytokine milieu for spontaneous development of IL-17+ Th cells that cause autoimmune arthritis, " Journal of Experimental Medicine, vol. 204, no. 1, pp. 41-47, 2007.
    • (2007) Journal of Experimental Medicine , vol.204 , Issue.1 , pp. 41-47
    • Hirota, K.1    Hashimoto, M.2    Yoshitomi, H.3
  • 39
    • 77956413981 scopus 로고    scopus 로고
    • Modulation of IL-17 and Foxp3 expression in the prevention of autoimmune arthritis in mice
    • Article IDe10558
    • J. Duarte, A. Agua-Doce, V. G. Oliveira, J. E. Fonseca, and L. Grac, "Modulation of IL-17 and Foxp3 expression in the prevention of autoimmune arthritis in mice, " PLoS ONE, vol. 5, no. 5, Article IDe10558, 2010.
    • (2010) PLoS ONE , vol.5 , Issue.5
    • Duarte, J.1    Agua-Doce, A.2    Oliveira, V.G.3    Fonseca, J.E.4    Grac, L.5
  • 40
    • 84904266329 scopus 로고    scopus 로고
    • GM-CSF but not IL-17 is critical for the development of severe interstitial lung disease in SKG mice
    • A. Shiomi, T. Usui, Y. Ishikawa, M. Shimizu, K. Murakami, and T. Mimori, "GM-CSF but not IL-17 is critical for the development of severe interstitial lung disease in SKG mice, " Journal of Immunology, vol. 193, no. 2, pp. 849-859, 2014.
    • (2014) Journal of Immunology , vol.193 , Issue.2 , pp. 849-859
    • Shiomi, A.1    Usui, T.2    Ishikawa, Y.3    Shimizu, M.4    Murakami, K.5    Mimori, T.6
  • 41
    • 77953913586 scopus 로고    scopus 로고
    • Gut-residing segmented filamentous bacteria drive autoimmune arthritis via T helper 17 cells
    • H.-J. Wu, I. I. Ivanov, J. Darce et al., "Gut-residing segmented filamentous bacteria drive autoimmune arthritis via T helper 17 cells, " Immunity, vol. 32, no. 6, pp. 815-827, 2010.
    • (2010) Immunity , vol.32 , Issue.6 , pp. 815-827
    • Wu, H.-J.1    Ivanov, I.I.2    Darce, J.3
  • 42
    • 84877089880 scopus 로고    scopus 로고
    • Neutrophils are essential as a source of IL-17 in the effector phase of arthritis
    • Article ID e62231
    • M. Katayama, K. Ohmura, N. Yukawa et al., "Neutrophils are essential as a source of IL-17 in the effector phase of arthritis, " PLoS ONE, vol. 8, no. 5, Article ID e62231, 2013.
    • (2013) PLoS ONE , vol.8 , Issue.5
    • Katayama, M.1    Ohmura, K.2    Yukawa, N.3
  • 43
    • 80054787419 scopus 로고    scopus 로고
    • Il-17RA signaling amplifies antibody-induced arthritis
    • Article ID e26342
    • C. D. Sadik, N. D. Kim, E. Alekseeva, and A. D. Luster, "Il-17RA signaling amplifies antibody-induced arthritis, " PLoS ONE, vol. 6, no. 10, Article ID e26342, 2011.
    • (2011) PLoS ONE , vol.6 , Issue.10
    • Sadik, C.D.1    Kim, N.D.2    Alekseeva, E.3    Luster, A.D.4
  • 45
    • 0038623916 scopus 로고    scopus 로고
    • IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist
    • S. Nakae, S. Saijo, R. Horai, K. Sudo, S. Mori, and Y. Iwakura, "IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist, " Proceedings of the National Academy of Sciences of the United States of America, vol. 100, no. 10, pp. 5986-5990, 2003.
    • (2003) Proceedings of the National Academy of Sciences of the United States of America , vol.100 , Issue.10 , pp. 5986-5990
    • Nakae, S.1    Saijo, S.2    Horai, R.3    Sudo, K.4    Mori, S.5    Iwakura, Y.6
  • 46
    • 84870030730 scopus 로고    scopus 로고
    • IL-17-deficient allogeneic bone marrow transplantation prevents the induction of collagen-induced arthritis in DBA/1J mice
    • M.-J. Park, H.-S. Park, H.-J. Oh et al., "IL-17-deficient allogeneic bone marrow transplantation prevents the induction of collagen-induced arthritis in DBA/1J mice, " Experimental and Molecular Medicine, vol. 44, no. 11, pp. 694-705, 2012.
    • (2012) Experimental and Molecular Medicine , vol.44 , Issue.11 , pp. 694-705
    • Park, M.-J.1    Park, H.-S.2    Oh, H.-J.3
  • 47
    • 1042267236 scopus 로고    scopus 로고
    • Treatment with a neutralizing anti-murine interleukin-17 antibody after the onset of collagen-induced arthritis reduces joint inflammation, cartilage destruction, and bone erosion
    • E. Lubberts, M. I. Koenders, B. Oppers-Walgreen et al., "Treatment with a neutralizing anti-murine interleukin-17 antibody after the onset of collagen-induced arthritis reduces joint inflammation, cartilage destruction, and bone erosion, " Arthritis and Rheumatism, vol. 50, no. 2, pp. 650-659, 2004.
    • (2004) Arthritis and Rheumatism , vol.50 , Issue.2 , pp. 650-659
    • Lubberts, E.1    Koenders, M.I.2    Oppers-Walgreen, B.3
  • 48
    • 84868564380 scopus 로고    scopus 로고
    • A bispecific antibody against IL-1β and IL-17A is beneficial for experimental rheumatoid arthritis
    • J. Qi, F. Kan, X. Ye et al., "A bispecific antibody against IL-1β and IL-17A is beneficial for experimental rheumatoid arthritis, " International Immunopharmacology, vol. 14, no. 4, pp. 770-778, 2012.
    • (2012) International Immunopharmacology , vol.14 , Issue.4 , pp. 770-778
    • Qi, J.1    Kan, F.2    Ye, X.3
  • 49
    • 84872805719 scopus 로고    scopus 로고
    • Synergistic effects of interleukin-1β and interleukin-17A antibodies on collagen-induced arthritis mouse model
    • Y. Zhang, G. Ren, M. Guo et al., "Synergistic effects of interleukin-1β and interleukin-17A antibodies on collagen-induced arthritis mouse model, " International Immunopharmacology, vol. 15, no. 2, pp. 199-205, 2013.
    • (2013) International Immunopharmacology , vol.15 , Issue.2 , pp. 199-205
    • Zhang, Y.1    Ren, G.2    Guo, M.3
  • 50
    • 84900988387 scopus 로고    scopus 로고
    • Therapeutic efficacy of three bispecific antibodies on collagen-induced arthritis mouse model
    • Q. Li, G. Ren, L. Xu et al., "Therapeutic efficacy of three bispecific antibodies on collagen-induced arthritis mouse model, " International Immunopharmacology, vol. 21, no. 1, pp. 119-127, 2014.
    • (2014) International Immunopharmacology , vol.21 , Issue.1 , pp. 119-127
    • Li, Q.1    Ren, G.2    Xu, L.3
  • 51
    • 84936743560 scopus 로고    scopus 로고
    • Complementary action of granulocytemacrophage colonystimulating factor and interleukin-17A induces interleukin-23, receptor activator of nuclear factor-κB ligand, and matrix metalloproteinases and drives bone and cartilage pathology in experimental arthritis: Rationale for combination therapy in rheumatoid arthritis
    • article 163
    • A. E. M. van Nieuwenhuijze, F. A. van de Loo, B. Walgreen et al., "Complementary action of granulocytemacrophage colonystimulating factor and interleukin-17A induces interleukin-23, receptor activator of nuclear factor-κB ligand, and matrix metalloproteinases and drives bone and cartilage pathology in experimental arthritis: rationale for combination therapy in rheumatoid arthritis, " Arthritis Research & Therapy, vol. 17, article 163, no. 1, 2015.
    • (2015) Arthritis Research & Therapy , vol.17 , Issue.1
    • Van Nieuwenhuijze, A.E.M.1    Van De Loo, F.A.2    Walgreen, B.3
  • 52
    • 38449102562 scopus 로고    scopus 로고
    • IL-17B and IL-17C are associated with TNF-α production and contribute to the exacerbation of inflammatory arthritis
    • Y. Yamaguchi, K. Fujio, H. Shoda et al., "IL-17B and IL-17C are associated with TNF-α production and contribute to the exacerbation of inflammatory arthritis, " The Journal of Immunology, vol. 179, no. 10, pp. 7128-7136, 2007.
    • (2007) The Journal of Immunology , vol.179 , Issue.10 , pp. 7128-7136
    • Yamaguchi, Y.1    Fujio, K.2    Shoda, H.3
  • 53
    • 84876713573 scopus 로고    scopus 로고
    • A canonical Vγ4Vδ4+ γδ T cell population with distinct stimulation requirements which promotes theTh17 response
    • C. L. Roark, Y. Huang, N. Jin et al., "A canonical Vγ4Vδ4+ γδ T cell population with distinct stimulation requirements which promotes theTh17 response, " Immunologic Research, vol. 55, no. 1-3, pp. 217-230, 2013.
    • (2013) Immunologic Research , vol.55 , Issue.1-3 , pp. 217-230
    • Roark, C.L.1    Huang, Y.2    Jin, N.3
  • 54
    • 55049118394 scopus 로고    scopus 로고
    • Interleukin-17 promotes autoimmunity by triggering a positive-feedback loop via interleukin-6 induction
    • H. Ogura, M. Murakami, Y. Okuyama et al., "Interleukin-17 promotes autoimmunity by triggering a positive-feedback loop via interleukin-6 induction, " Immunity, vol. 29, no. 4, pp. 628-636, 2008.
    • (2008) Immunity , vol.29 , Issue.4 , pp. 628-636
    • Ogura, H.1    Murakami, M.2    Okuyama, Y.3
  • 55
    • 57349083145 scopus 로고    scopus 로고
    • Interleukin-6 blockade suppresses autoimmune arthritis in mice by the inhibition of inflammatory Th17 responses
    • M. Fujimoto, S. Serada, M. Mihara et al., "Interleukin-6 blockade suppresses autoimmune arthritis in mice by the inhibition of inflammatory Th17 responses, " Arthritis and Rheumatism, vol. 58, no. 12, pp. 3710-3719, 2008.
    • (2008) Arthritis and Rheumatism , vol.58 , Issue.12 , pp. 3710-3719
    • Fujimoto, M.1    Serada, S.2    Mihara, M.3
  • 56
    • 33751521013 scopus 로고    scopus 로고
    • Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction
    • K. Sato, A. Suematsu, K. Okamoto et al., "Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction, " The Journal of Experimental Medicine, vol. 203, no. 12, pp. 2673-2682, 2006.
    • (2006) The Journal of Experimental Medicine , vol.203 , Issue.12 , pp. 2673-2682
    • Sato, K.1    Suematsu, A.2    Okamoto, K.3
  • 57
    • 0033933776 scopus 로고    scopus 로고
    • IL-4 gene therapy for collagen arthritis suppresses synovial IL-17 and osteoprotegerin ligand and prevents bone erosion
    • E. Lubberts, L. A. B. Joosten, M. Chabaud et al., "IL-4 gene therapy for collagen arthritis suppresses synovial IL-17 and osteoprotegerin ligand and prevents bone erosion, " Journal of Clinical Investigation, vol. 105, no. 12, pp. 1697-1710, 2000.
    • (2000) Journal of Clinical Investigation , vol.105 , Issue.12 , pp. 1697-1710
    • Lubberts, E.1    Joosten, L.A.B.2    Chabaud, M.3
  • 58
    • 0346962972 scopus 로고    scopus 로고
    • Divergent pro-and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation
    • C. A. Murphy, C. L. Langrish, Y. Chen et al., "Divergent pro-and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation, " Journal of Experimental Medicine, vol. 198, no. 12, pp. 1951-1957, 2003.
    • (2003) Journal of Experimental Medicine , vol.198 , Issue.12 , pp. 1951-1957
    • Murphy, C.A.1    Langrish, C.L.2    Chen, Y.3
  • 59
    • 79961115376 scopus 로고    scopus 로고
    • Local expression of interleukin-27 ameliorates collagen-induced arthritis
    • S. R. Pickens, N. D. Chamberlain, M. V. Volin et al., "Local expression of interleukin-27 ameliorates collagen-induced arthritis, " Arthritis and Rheumatism, vol. 63, no. 8, pp. 2289-2298, 2011.
    • (2011) Arthritis and Rheumatism , vol.63 , Issue.8 , pp. 2289-2298
    • Pickens, S.R.1    Chamberlain, N.D.2    Volin, M.V.3
  • 60
    • 84929650379 scopus 로고    scopus 로고
    • IL-37 alleviates rheumatoid arthritis by suppressing IL-17 and IL-17-triggering cytokine production and limiting Th17 cell proliferation
    • L. Ye, B. Jiang, J. Deng et al., "IL-37 alleviates rheumatoid arthritis by suppressing IL-17 and IL-17-triggering cytokine production and limiting Th17 cell proliferation, " The Journal of Immunology, vol. 194, no. 11, pp. 5110-5119, 2015.
    • (2015) The Journal of Immunology , vol.194 , Issue.11 , pp. 5110-5119
    • Ye, L.1    Jiang, B.2    Deng, J.3
  • 61
    • 51849147995 scopus 로고    scopus 로고
    • Natural killer cell degeneration exacerbates experimental arthritis in mice via enhanced interleukin-17 production
    • C. K. C. Lo, Q. L. K. Lam, L. Sun et al., "Natural killer cell degeneration exacerbates experimental arthritis in mice via enhanced interleukin-17 production, " Arthritis and Rheumatism, vol. 58, no. 9, pp. 2700-2711, 2008.
    • (2008) Arthritis and Rheumatism , vol.58 , Issue.9 , pp. 2700-2711
    • Lo, C.K.C.1    Lam, Q.L.K.2    Sun, L.3
  • 62
    • 84856616941 scopus 로고    scopus 로고
    • Interleukin-10 produced by B cells is crucial for the suppression of Th17/Th1 responses, induction of T regulatory type 1 cells and reduction of collagen-induced arthritis
    • article R32
    • N. A. Carter, E. C. Rosser, and C. Mauri, "Interleukin-10 produced by B cells is crucial for the suppression of Th17/Th1 responses, induction of T regulatory type 1 cells and reduction of collagen-induced arthritis, " Arthritis Research and Therapy, vol. 14, no. 1, article R32, 2012.
    • (2012) Arthritis Research and Therapy , vol.14 , Issue.1
    • Carter, N.A.1    Rosser, E.C.2    Mauri, C.3
  • 63
    • 84055178107 scopus 로고    scopus 로고
    • IL-10 signaling in CD4+ T cells is critical for the pathogenesis of collagen-induced arthritis
    • article R212
    • J. Tao, M. Kamanaka, J. Hao et al., "IL-10 signaling in CD4+ T cells is critical for the pathogenesis of collagen-induced arthritis, " Arthritis Research and Therapy, vol. 13, no. 6, article R212, 2011.
    • (2011) Arthritis Research and Therapy , vol.13 , Issue.6
    • Tao, J.1    Kamanaka, M.2    Hao, J.3
  • 64
    • 80855131595 scopus 로고    scopus 로고
    • Active immunization against IL-23p19 improves experimental arthritis
    • R. A. Ratsimandresy, E. Duvallet, E. Assier et al., "Active immunization against IL-23p19 improves experimental arthritis, " Vaccine, vol. 29, no. 50, pp. 9329-9336, 2011.
    • (2011) Vaccine , vol.29 , Issue.50 , pp. 9329-9336
    • Ratsimandresy, R.A.1    Duvallet, E.2    Assier, E.3
  • 66
    • 69849090650 scopus 로고    scopus 로고
    • Effector mechanisms of interleukin-17 in collagen-induced arthritis in the absence of interferon-γ and counteraction by interferon-γ
    • article R122
    • H. Kelchtermans, E. Schurgers, L. Geboes et al., "Effector mechanisms of interleukin-17 in collagen-induced arthritis in the absence of interferon-γ and counteraction by interferon-γ, " Arthritis Research and Therapy, vol. 11, no. 4, article R122, 2009.
    • (2009) Arthritis Research and Therapy , vol.11 , Issue.4
    • Kelchtermans, H.1    Schurgers, E.2    Geboes, L.3
  • 67
    • 0037105475 scopus 로고    scopus 로고
    • IL-4 and IL-12 regulate proteoglycan-induced arthritis through stat-dependent mechanisms
    • A. Finnegan, M. J. Grusby, C. D. Kaplan et al., "IL-4 and IL-12 regulate proteoglycan-induced arthritis through stat-dependent mechanisms, " Journal of Immunology, vol. 169, no. 6, pp. 3345-3352, 2002.
    • (2002) Journal of Immunology , vol.169 , Issue.6 , pp. 3345-3352
    • Finnegan, A.1    Grusby, M.J.2    Kaplan, C.D.3
  • 68
    • 47949090745 scopus 로고    scopus 로고
    • Development of proteoglycan-induced arthritis is independent of IL-17
    • P. D. Doodes, Y. Cao, K. M. Hamel et al., "Development of proteoglycan-induced arthritis is independent of IL-17, "TheJournal of Immunology, vol. 181, no. 1, pp. 329-337, 2008.
    • (2008) TheJournal of Immunology , vol.181 , Issue.1 , pp. 329-337
    • Doodes, P.D.1    Cao, Y.2    Hamel, K.M.3
  • 69
    • 77949314815 scopus 로고    scopus 로고
    • IFN-γ regulates the requirement for IL-17 in proteoglycan-induced arthritis
    • P. D. Doodes, Y. Cao, K. M. Hamel et al., "IFN-γ regulates the requirement for IL-17 in proteoglycan-induced arthritis, " Journal of Immunology, vol. 184, no. 3, pp. 1552-1559, 2010.
    • (2010) Journal of Immunology , vol.184 , Issue.3 , pp. 1552-1559
    • Doodes, P.D.1    Cao, Y.2    Hamel, K.M.3
  • 70
    • 77958072084 scopus 로고    scopus 로고
    • Effects of AIN457, a fully human antibody to interleukin-17A, on psoriasis, rheumatoid arthritis, and uveitis
    • Article ID 52ra72
    • W. Hueber, D. D. Patel, T. Dryja et al., "Effects of AIN457, a fully human antibody to interleukin-17A, on psoriasis, rheumatoid arthritis, and uveitis, " Science Translational Medicine, vol. 2, no. 52, Article ID 52ra72, 2010.
    • (2010) Science Translational Medicine , vol.2 , Issue.52
    • Hueber, W.1    Patel, D.D.2    Dryja, T.3
  • 71
    • 84877603562 scopus 로고    scopus 로고
    • Efficacy and safety of secukinumab in patients with rheumatoid arthritis: A phase II, dose-finding, double-blind, randomised, placebo controlled study
    • M. C. Genovese, P. Durez, H. B. Richards et al., "Efficacy and safety of secukinumab in patients with rheumatoid arthritis: a phase II, dose-finding, double-blind, randomised, placebo controlled study, " Annals of the Rheumatic Diseases, vol. 72, no. 6, pp. 863-869, 2013.
    • (2013) Annals of the Rheumatic Diseases , vol.72 , Issue.6 , pp. 863-869
    • Genovese, M.C.1    Durez, P.2    Richards, H.B.3
  • 72
    • 84895465850 scopus 로고    scopus 로고
    • One-year efficacy and safety results of secukinumab in patientswith rheumatoid arthritis: Phase II, dose-finding, double-blind, randomized, placebo-controlled study
    • M. C. Genovese, P. Durez, H. B. Richards et al., "One-year efficacy and safety results of secukinumab in patientswith rheumatoid arthritis: phase II, dose-finding, double-blind, randomized, placebo-controlled study, " Journal of Rheumatology, vol. 41, no. 3, pp. 414-421, 2014.
    • (2014) Journal of Rheumatology , vol.41 , Issue.3 , pp. 414-421
    • Genovese, M.C.1    Durez, P.2    Richards, H.B.3
  • 73
    • 77950535421 scopus 로고    scopus 로고
    • LY2439821, a humanized anti-interleukin-17 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A phase i randomized, double-blind, placebo-controlled, proofof-concept study
    • M. C. Genovese, F. Van den Bosch, S. A. Roberson et al., "LY2439821, a humanized anti-interleukin-17 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: a phase I randomized, double-blind, placebo-controlled, proofof-concept study, " Arthritis and Rheumatism, vol. 62, no. 4, pp. 929-939, 2010.
    • (2010) Arthritis and Rheumatism , vol.62 , Issue.4 , pp. 929-939
    • Genovese, M.C.1    Bosch Den F.Van2    Roberson, S.A.3
  • 74
    • 84903478179 scopus 로고    scopus 로고
    • A phase II randomized study of subcutaneous ixekizumab, an anti-interleukin-17monoclonal antibody, in rheumatoid arthritis patients who were naive to biologic agents or had an inadequate response to tumor necrosis factor inhibitors
    • M. C. Genovese, M. Greenwald, C.-S. Cho et al., "A phase II randomized study of subcutaneous ixekizumab, an anti-interleukin-17monoclonal antibody, in rheumatoid arthritis patients who were naive to biologic agents or had an inadequate response to tumor necrosis factor inhibitors, " Arthritis & Rheumatology, vol. 66, no. 7, pp. 1693-1704, 2014.
    • (2014) Arthritis & Rheumatology , vol.66 , Issue.7 , pp. 1693-1704
    • Genovese, M.C.1    Greenwald, M.2    Cho, C.-S.3
  • 75
    • 84886226230 scopus 로고    scopus 로고
    • A phase Ib multiple ascending dose study evaluating safety, pharmacokinetics, and early clinical response of brodalumab, a human anti-IL-17R antibody, in methotrexate-resistant rheumatoid arthritis
    • article R164
    • D. A. Martin, M. Churchill, L. F. Flores-Suarez et al., "A phase Ib multiple ascending dose study evaluating safety, pharmacokinetics, and early clinical response of brodalumab, a human anti-IL-17R antibody, in methotrexate-resistant rheumatoid arthritis, " Arthritis Research and Therapy, vol. 15, no. 5, article R164, 2013.
    • (2013) Arthritis Research and Therapy , vol.15 , Issue.5
    • Martin, D.A.1    Churchill, M.2    Flores-Suarez, L.F.3
  • 76
    • 84940478173 scopus 로고    scopus 로고
    • A study to evaluate the safety, tolerability, and efficacy of brodalumab in subjects with rheumatoid arthritis and an inadequate response to methotrexate
    • K. Pavelka, Y. Chon, R. Newmark, S.-L. Lin, S. Baumgartner, and N. Erondu, "A study to evaluate the safety, tolerability, and efficacy of brodalumab in subjects with rheumatoid arthritis and an inadequate response to methotrexate, " The Journal of Rheumatology, vol. 42, no. 6, pp. 912-919, 2015.
    • (2015) The Journal of Rheumatology , vol.42 , Issue.6 , pp. 912-919
    • Pavelka, K.1    Chon, Y.2    Newmark, R.3    Lin, S.-L.4    Baumgartner, S.5    Erondu, N.6
  • 77
    • 0345414139 scopus 로고    scopus 로고
    • Altered thymic Tcell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice
    • N. Sakaguchi, T. Takahashi, H. Hata et al., "Altered thymic Tcell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice, " Nature, vol. 426, no. 6965, pp. 454-460, 2003.
    • (2003) Nature , vol.426 , Issue.6965 , pp. 454-460
    • Sakaguchi, N.1    Takahashi, T.2    Hata, H.3
  • 79
    • 53349173070 scopus 로고    scopus 로고
    • Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine
    • I. I. Ivanov, R. D. L. Frutos, N. Manel et al., "Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine, " Cell Host and Microbe, vol. 4, no. 4, pp. 337-349, 2008.
    • (2008) Cell Host and Microbe , vol.4 , Issue.4 , pp. 337-349
    • Ivanov, I.I.1    Frutos, R.D.L.2    Manel, N.3
  • 80
    • 0344585384 scopus 로고    scopus 로고
    • Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice
    • S. Nakae, A. Nambu, K. Sudo, and Y. Iwakura, "Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice, " Journal of Immunology, vol. 171, no. 11, pp. 6173-6177, 2003.
    • (2003) Journal of Immunology , vol.171 , Issue.11 , pp. 6173-6177
    • Nakae, S.1    Nambu, A.2    Sudo, K.3    Iwakura, Y.4
  • 81
    • 33846249233 scopus 로고    scopus 로고
    • Interleukin-17 as a molecular target in immune-mediated arthritis: Immunoregulatory properties of genetically modified murine dendritic cells that secrete interleukin-4
    • S. Sarkar, L. A. Tesmer, V. Hindnavis, J. L. Endres, and D. A. Fox, "Interleukin-17 as a molecular target in immune-mediated arthritis: immunoregulatory properties of genetically modified murine dendritic cells that secrete interleukin-4, " Arthritis and Rheumatism, vol. 56, no. 1, pp. 89-100, 2007.
    • (2007) Arthritis and Rheumatism , vol.56 , Issue.1 , pp. 89-100
    • Sarkar, S.1    Tesmer, L.A.2    Hindnavis, V.3    Endres, J.L.4    Fox, D.A.5
  • 82
    • 65549089043 scopus 로고    scopus 로고
    • Th1/Th17 polarization and acquisition of an arthritogenic phenotype in arthritis-susceptible BALB/c, but not in MHCmatched, arthritis-resistant DBA/2 mice
    • F. Boldizsar, O. Tarjanyi, P. Nemeth, K. Mikecz, and T. T. Glant, "Th1/Th17 polarization and acquisition of an arthritogenic phenotype in arthritis-susceptible BALB/c, but not in MHCmatched, arthritis-resistant DBA/2 mice, " International Immunology, vol. 21, no. 5, pp. 511-522, 2009.
    • (2009) International Immunology , vol.21 , Issue.5 , pp. 511-522
    • Boldizsar, F.1    Tarjanyi, O.2    Nemeth, P.3    Mikecz, K.4    Glant, T.T.5
  • 83
    • 0023254937 scopus 로고
    • Proteogly can-induced arthritis in BALB/c mice. Clinical features and histopathology
    • T. T. Glant, K. Mikecz, A. Arzoumanian, and A. R. Poole, "Proteogly can-induced arthritis in BALB/c mice. Clinical features and histopathology, " Arthritis and Rheumatism, vol. 30, no. 2, pp. 201-212, 1987.
    • (1987) Arthritis and Rheumatism , vol.30 , Issue.2 , pp. 201-212
    • Glant, T.T.1    Mikecz, K.2    Arzoumanian, A.3    Poole, A.R.4
  • 84
    • 0141564778 scopus 로고    scopus 로고
    • Proteoglycan-induced arthritis: Immune regulation, cellular mechanisms, and genetics
    • T. T. Glant, A. Finnegan, and K. Mikecz, "Proteoglycan-induced arthritis: immune regulation, cellular mechanisms, and genetics, " Critical Reviews in Immunology, vol. 23, no. 3, pp. 199-250, 2003.
    • (2003) Critical Reviews in Immunology , vol.23 , Issue.3 , pp. 199-250
    • Glant, T.T.1    Finnegan, A.2    Mikecz, K.3
  • 85
    • 0033571645 scopus 로고    scopus 로고
    • Proteoglycan (aggrecan)-induced arthritis in BALB/c mice is a Th1-type disease regulated byTh2cytokines
    • A. Finnegan, K. Mikecz, P. Tao, and T. T. Glant, "Proteoglycan (aggrecan)-induced arthritis in BALB/c mice is a Th1-type disease regulated byTh2cytokines, " The Journal of Immunology, vol. 163, no. 10, pp. 5383-5390, 1999.
    • (1999) The Journal of Immunology , vol.163 , Issue.10 , pp. 5383-5390
    • Finnegan, A.1    Mikecz, K.2    Tao, P.3    Glant, T.T.4
  • 86
    • 84925226246 scopus 로고    scopus 로고
    • Safety and efficacy of brodalumab for psoriasis after 120 weeks of treatment
    • K. Papp, C. Leonardi, A. Menter et al., "Safety and efficacy of brodalumab for psoriasis after 120 weeks of treatment, " Journal of the American Academy of Dermatology, vol. 71, no. 6, pp. 1183-1190. e3, 2014.
    • (2014) Journal of the American Academy of Dermatology , vol.71 , Issue.6 , pp. 1183-1190e3
    • Papp, K.1    Leonardi, C.2    Menter, A.3
  • 87
    • 84866934694 scopus 로고    scopus 로고
    • Targeting IL-17 and TH17 cells in chronic inflammation
    • P. Miossec and J. K. Kolls, "Targeting IL-17 and TH17 cells in chronic inflammation, " Nature Reviews Drug Discovery, vol. 11, no. 10, pp. 763-776, 2012.
    • (2012) Nature Reviews Drug Discovery , vol.11 , Issue.10 , pp. 763-776
    • Miossec, P.1    Kolls, J.K.2
  • 88
    • 84891740105 scopus 로고    scopus 로고
    • Efficacy and safety of secukinumab, a fully human anti-interleukin-17A monoclonal antibody, in patients with moderate-to-severe psoriatic arthritis: A 24-week, randomised, double-blind, placebo-controlled, phase II proof-of-concept trial
    • I. B. McInnes, J. Sieper, J. Braun et al., "Efficacy and safety of secukinumab, a fully human anti-interleukin-17A monoclonal antibody, in patients with moderate-to-severe psoriatic arthritis: a 24-week, randomised, double-blind, placebo-controlled, phase ii proof-of-concept trial, " Annals of the Rheumatic Diseases, vol. 73, no. 2, pp. 349-356, 2014.
    • (2014) Annals of the Rheumatic Diseases , vol.73 , Issue.2 , pp. 349-356
    • McInnes, I.B.1    Sieper, J.2    Braun, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.